IS4350A - Trísýklísk 5,6-díhýdró-9H-pýrazóló[3,4c]-1,2,4-tríazóló[4,3a]pýridín, notkun þeirra og lyfjablanda - Google Patents

Trísýklísk 5,6-díhýdró-9H-pýrazóló[3,4c]-1,2,4-tríazóló[4,3a]pýridín, notkun þeirra og lyfjablanda

Info

Publication number
IS4350A
IS4350A IS4350A IS4350A IS4350A IS 4350 A IS4350 A IS 4350A IS 4350 A IS4350 A IS 4350A IS 4350 A IS4350 A IS 4350A IS 4350 A IS4350 A IS 4350A
Authority
IS
Iceland
Prior art keywords
triazolo
pyrazolo
tricyclic
dihydro
pyridine
Prior art date
Application number
IS4350A
Other languages
English (en)
Other versions
IS1913B (is
Inventor
Jacob Duplantier Allen
Cooper Kelvin
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of IS4350A publication Critical patent/IS4350A/is
Publication of IS1913B publication Critical patent/IS1913B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IS4350A 1995-06-06 1996-06-03 Trísýklísk 5,6-díhýdró-9H-pýrazóló[3,4c]-1,2,4-tríazóló[4,3a]pýridín, notkun þeirra og lyfjablanda IS1913B (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002223624A CA2223624C (en) 1995-06-06 1995-06-06 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-.alpha.]pyridines
PCT/IB1995/000429 WO1996039408A1 (en) 1995-06-06 1995-06-06 TRICYCLIC 5,6-DIHYDRO-9H-PYRAZOLO[3,4-c]-1,2,4-TRIAZOLO[4,3-α]PYRIDINES
HU9601541A HUP9601541A3 (en) 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
IS4350A true IS4350A (is) 1996-12-07
IS1913B IS1913B (is) 2004-02-03

Family

ID=89994031

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4350A IS1913B (is) 1995-06-06 1996-06-03 Trísýklísk 5,6-díhýdró-9H-pýrazóló[3,4c]-1,2,4-tríazóló[4,3a]pýridín, notkun þeirra og lyfjablanda

Country Status (43)

Country Link
US (1) US6004974A (is)
EP (1) EP0837860B1 (is)
JP (1) JP3107827B2 (is)
KR (2) KR100191972B1 (is)
CN (1) CN1061044C (is)
AP (1) AP609A (is)
AR (1) AR002745A1 (is)
AT (1) ATE214700T1 (is)
AU (1) AU694871B2 (is)
BG (1) BG62568B1 (is)
BR (1) BR9602627A (is)
CA (1) CA2223624C (is)
CO (1) CO4700460A1 (is)
CZ (1) CZ287251B6 (is)
DE (1) DE69525978T2 (is)
DK (1) DK0837860T3 (is)
DZ (1) DZ2044A1 (is)
ES (1) ES2172583T3 (is)
FI (1) FI114097B (is)
HR (1) HRP960268B1 (is)
HU (1) HUP9601541A3 (is)
IL (1) IL118485A (is)
IS (1) IS1913B (is)
LV (1) LV11620B (is)
MA (1) MA23893A1 (is)
MX (1) MX9709897A (is)
MY (1) MY116527A (is)
NO (1) NO306256B1 (is)
NZ (1) NZ286734A (is)
OA (1) OA10458A (is)
PL (1) PL184195B1 (is)
PT (1) PT837860E (is)
RO (1) RO115881B1 (is)
RU (1) RU2161158C2 (is)
SA (1) SA96170065B1 (is)
SG (1) SG54341A1 (is)
SI (1) SI9600186A (is)
SK (1) SK282167B6 (is)
TN (1) TNSN96083A1 (is)
TR (1) TR199600482A1 (is)
TW (1) TW460469B (is)
WO (1) WO1996039408A1 (is)
YU (1) YU49346B (is)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2792938B1 (fr) 1999-04-28 2001-07-06 Warner Lambert Co NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
EP1380585B1 (en) * 1999-04-30 2004-11-10 Pfizer Products Inc. Pyrazolopyridinone as intermediate
US6326495B2 (en) * 1999-04-30 2001-12-04 Pfizer Inc. Process for preparing 8-cyclopentyl-6-ethyl-3-[substituted]-5,8-dihydro-4H-1,2,3a,7,8-pentaaza-as-indacenes and intermediates useful therein
TR200201317T2 (tr) 1999-08-21 2002-11-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Sinerjistik kombinasyon.
US6555572B2 (en) 2000-03-16 2003-04-29 Inflazyme Pharmaceuticals Ltd. Benzylated PDE4 inhibitors
JP2004530705A (ja) * 2001-05-25 2004-10-07 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト 閉塞性気道疾患及びその他の炎症性疾患を治療するためのｐｄｅ４インヒビター及びチオトロピウム又はその誘導体の組み合わせ
KR20040007605A (ko) * 2001-05-25 2004-01-24 화이자 인코포레이티드 폐색성 기도 질환을 치료하기 위한 ｐｄｅ4 억제제 및항콜린제의 복합물
GB0122031D0 (en) * 2001-09-12 2001-10-31 Pfizer Ltd Use of pde4 inhibitors in a dry powder inhaler
GB0129395D0 (en) * 2001-12-07 2002-01-30 Pfizer Ltd Pharmaceutical combination
US20050107420A1 (en) * 2002-05-23 2005-05-19 Boehringe Ingelheim Pharma Gmbh & Co. Kg Combination of a PDE4 inhibitor and tiotropium or derivative thereof for treating obstructive airways and other inflammatory diseases
US7153824B2 (en) 2003-04-01 2006-12-26 Applied Research Systems Ars Holding N.V. Inhibitors of phosphodiesterases in infertility
WO2006075748A1 (ja) * 2005-01-17 2006-07-20 Santen Pharmaceutical Co., Ltd. アレルギー性結膜疾患治療剤
DK1898903T3 (da) * 2005-06-10 2013-07-01 Merck Sharp & Dohme Inhibitorer af Akt-aktivitet
JP2009512676A (ja) 2005-10-19 2009-03-26 ランバクシー ラボラトリーズ リミテッド ムスカリン性受容体アンタゴニストの医薬組成物
CN102764440A (zh) 2006-07-05 2012-11-07 奈科明有限责任公司 用于治疗炎症性肺部疾病的HMG-CoA还原酶抑制剂与磷酸二酯酶4抑制剂的组合
CA2739148A1 (en) * 2008-10-17 2010-04-22 Boehringer Ingelheim International Gmbh Tetra-aza-heterocycles as phosphatidylinositol-3-kinases (pi3-kinases) inhibitor
ES2527363T3 (es) 2009-12-04 2015-01-22 Nerviano Medical Sciences S.R.L. Derivados de triciclopirazol
WO2013084182A1 (en) 2011-12-08 2013-06-13 Glenmark Pharmaceuticals S.A. Pharmaceutical composition that includes a pde4 enzyme inhibitor and an analgesic agent

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697532A (en) * 1970-08-12 1972-10-10 Squibb & Sons Inc 5-methyldipyrazolo {8 3,4-b;3{40 ,4{40 -d{9 {0 pyridin-3(2h)-ones
SU1048746A1 (ru) * 1982-01-29 1987-12-30 Институт физико-органической химии и углехимии АН УССР Гидробромид 8-адамантил-1,з-диметилимидазо 4,5-с имидазо 1,2-а пиридин-2-она,обладающий спазмолитическим действием
FR2579208B1 (fr) * 1985-03-22 1987-05-07 Sanofi Sa Nouveaux derives de le 5-h pyrido (3', 4' : 4,5) pyrrolo (3,2-c) pyridine, leur procede de preparation et leur activite antitumorale
US4940715A (en) * 1988-05-17 1990-07-10 Kissei Pharmaceutical Co., Ltd. 5H-pyrazolo[4,3-A] quinolizin-5-one compounds exhibiting therapeutic activities
CA2030056C (en) * 1989-11-17 1995-10-17 Karl D. Hargrave 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines and their use in the prevention or treatment of hiv infection
BR9406946A (pt) * 1993-07-06 1996-08-06 Pfizer Tetra-hidro-pirazolpiridinas bicíclicas
CA2143143A1 (en) * 1994-03-08 1995-09-09 Toshihiko Tanaka 3-phenylpyrrolidine derivatives

Also Published As

Publication number Publication date
SI9600186A (en) 1997-04-30
KR970003440A (ko) 1997-01-28
JP3107827B2 (ja) 2000-11-13
FI114097B (fi) 2004-08-13
PL314459A1 (en) 1996-12-09
TNSN96083A1 (fr) 2005-03-15
DZ2044A1 (fr) 2002-07-21
WO1996039408A1 (en) 1996-12-12
KR100191972B1 (ko) 1999-06-15
YU49346B (sh) 2005-07-19
AU5477396A (en) 1996-12-19
ES2172583T3 (es) 2002-10-01
KR100225719B1 (en) 1999-10-15
AU694871B2 (en) 1998-07-30
IL118485A0 (en) 1996-09-12
LV11620B (en) 1997-04-20
BG62568B1 (bg) 2000-02-29
BG100640A (bg) 1997-03-31
DE69525978T2 (de) 2002-12-19
AP609A (en) 1997-09-03
SG54341A1 (en) 1998-11-16
PL184195B1 (pl) 2002-09-30
MA23893A1 (fr) 1996-12-31
DK0837860T3 (da) 2002-05-27
NO306256B1 (no) 1999-10-11
CO4700460A1 (es) 1998-12-29
CN1142499A (zh) 1997-02-12
IS1913B (is) 2004-02-03
HUP9601541A3 (en) 1997-05-28
MX9709897A (es) 1998-03-31
NO962320L (no) 1996-12-09
JPH10510242A (ja) 1998-10-06
CZ162696A3 (en) 1997-01-15
EP0837860B1 (en) 2002-03-20
SK71896A3 (en) 1997-05-07
DE69525978D1 (de) 2002-04-25
TW460469B (en) 2001-10-21
HUP9601541A2 (en) 1997-02-28
AP9600806A0 (en) 1996-07-31
RO115881B1 (ro) 2000-07-28
TR199600482A1 (tr) 1997-03-21
AR002745A1 (es) 1998-04-29
OA10458A (en) 2002-03-27
CN1061044C (zh) 2001-01-24
CZ287251B6 (en) 2000-10-11
SK282167B6 (sk) 2001-11-06
PT837860E (pt) 2002-07-31
SA96170065B1 (ar) 2005-12-21
MY116527A (en) 2004-02-28
FI974434A0 (fi) 1997-12-05
BR9602627A (pt) 1998-09-01
HRP960268B1 (en) 2002-12-31
IL118485A (en) 2000-02-17
CA2223624C (en) 2001-02-20
EP0837860A1 (en) 1998-04-29
CA2223624A1 (en) 1996-12-12
FI974434L (fi) 1997-12-05
RU2161158C2 (ru) 2000-12-27
HRP960268A2 (en) 1997-08-31
HU9601541D0 (en) 1996-07-29
NO962320D0 (no) 1996-06-05
ATE214700T1 (de) 2002-04-15
LV11620A (lv) 1996-12-20
US6004974A (en) 1999-12-21
YU34696A (sh) 1999-07-28
NZ286734A (en) 1998-02-26

Similar Documents

Publication Publication Date Title
HUP9900616A3 (en) Tricyclic compounds, their production, pharmaceutical compositions and use
IL118825A (en) Substituted 6-dimethylaminomethyl-1-phenyl-cyclohexane derivatives their preparation and use
IL116774A (en) Tricyclic pyrrolobenzo diazepines and similar compounds their preparation and pharmaceutical compositions containing them
IS4350A (is) Trísýklísk 5,6-díhýdró-9H-pýrazóló[3,4c]-1,2,4-tríazóló[4,3a]pýridín, notkun þeirra og lyfjablanda
IL116851A0 (en) 3-arylidene-2-oxindole derivatives their preparation and use
HUP0000474A3 (en) Arylethenesulfonamide derivatives and drug composition containing the same
IL112384A0 (en) Tetracyclic derivatives, their preparation and pharmaceutical compositions containing them
NZ281404A (en) Tricyclic pyrimidine derivatives and medicaments
GB9205051D0 (en) Pyrrolobenzodiazepine derivatives,their preparation,and compositions containing them
IS4839A (is) Nýjar bensazepín afleiður, læknislyf sem innihalda þær og notkun þeirra við að útbúa læknislyf
HU228234B1 (en) Rapamycin derivatives, pharmaceutical compositions containing them and their use
IS4570A (is) Imidazó[1,2-a]pýridín afleiður
IL118380A0 (en) Substituted pyridine derivatives their preparation and use
IL116773A0 (en) Tricyclic benzazepine compounds and their preparation
FI960867A7 (fi) Bentsatsepiinijohdannainen, sen farmaseuttinen seos ja välituote
NZ235270A (en) Diazepinone derivatives and pharmaceutical compositions
FI960160A7 (fi) Imidatso/1,2-a/pyratsin-4-onijohdannaiset, niiden valmistus ja niitä sisältävät lääkkeet
NZ241943A (en) PYRROLO [2,3-b] PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS
IL118443A0 (en) Cycloalkane-benzylidene derivatives their preparation and use
IL108343A0 (en) 9H-imidazo [1,2-a] benzimidazole-3-acetamide derivatives, their preparation and their therapeutic application
EE9800174A (et) 1,4-dihüdro-1,4-diokso-1H-naftaleeni tritsükliliste derivaatide kasutamine, uued ühendid ja nende kasutamine teraapias
IL123092A0 (en) Pyrazol-4-ylbenzoyl derivatives their preparation and use
HRP960117B1 (en) Bicyclic compounds, their preparation and use in pharmaceutical preparations
IL110782A0 (en) Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them
HUP0002659A3 (en) Benzo-5,6-cyclohepta[1,2-b]pyridine derivatives, pharmaceutical compositions containing them and their use