IL111071A - Process for the preparation of N-methyl-3-) 1-methyl-4-piperidinyl (- H1 indole-5-ethanesulfonamide and the new intermediate compound N methyl 2] 3) 1,2,3,6 tetrahydro - Google Patents

Process for the preparation of N-methyl-3-) 1-methyl-4-piperidinyl (- H1 indole-5-ethanesulfonamide and the new intermediate compound N methyl 2] 3) 1,2,3,6 tetrahydro

Info

Publication number
IL111071A
IL111071A IL11107194A IL11107194A IL111071A IL 111071 A IL111071 A IL 111071A IL 11107194 A IL11107194 A IL 11107194A IL 11107194 A IL11107194 A IL 11107194A IL 111071 A IL111071 A IL 111071A
Authority
IL
Israel
Prior art keywords
methyl
formula
compound
broad
hydrogen
Prior art date
Application number
IL11107194A
Other languages
English (en)
Hebrew (he)
Other versions
IL111071A0 (en
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IL111071A0 publication Critical patent/IL111071A0/xx
Publication of IL111071A publication Critical patent/IL111071A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL11107194A 1993-09-29 1994-09-28 Process for the preparation of N-methyl-3-) 1-methyl-4-piperidinyl (- H1 indole-5-ethanesulfonamide and the new intermediate compound N methyl 2] 3) 1,2,3,6 tetrahydro IL111071A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939320115A GB9320115D0 (en) 1993-09-29 1993-09-29 Process

Publications (2)

Publication Number Publication Date
IL111071A0 IL111071A0 (en) 1994-11-28
IL111071A true IL111071A (en) 1998-10-30

Family

ID=10742727

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11107194A IL111071A (en) 1993-09-29 1994-09-28 Process for the preparation of N-methyl-3-) 1-methyl-4-piperidinyl (- H1 indole-5-ethanesulfonamide and the new intermediate compound N methyl 2] 3) 1,2,3,6 tetrahydro

Country Status (32)

Country Link
US (2) US5659040A (cs)
EP (1) EP0721453B1 (cs)
JP (1) JP3411284B2 (cs)
CN (2) CN1132509A (cs)
AP (1) AP529A (cs)
AT (1) ATE228124T1 (cs)
AU (1) AU682219B2 (cs)
CA (1) CA2170645C (cs)
CO (1) CO4290351A1 (cs)
CZ (1) CZ287581B6 (cs)
DE (1) DE69431759T2 (cs)
DK (1) DK0721453T3 (cs)
ES (1) ES2187534T3 (cs)
FI (1) FI111162B (cs)
GB (1) GB9320115D0 (cs)
HK (1) HK1004218A1 (cs)
HR (1) HRP940613B1 (cs)
HU (1) HU226828B1 (cs)
IL (1) IL111071A (cs)
IS (1) IS1877B (cs)
MY (1) MY117934A (cs)
NO (1) NO309324B1 (cs)
NZ (1) NZ274159A (cs)
PE (1) PE18195A1 (cs)
PL (1) PL178456B1 (cs)
PT (1) PT721453E (cs)
RU (1) RU2143428C1 (cs)
SG (1) SG49322A1 (cs)
SI (1) SI0721453T1 (cs)
SK (1) SK282234B6 (cs)
WO (1) WO1995009166A1 (cs)
ZA (1) ZA947516B (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002509149A (ja) 1998-01-14 2002-03-26 ザ ユーエイビー リサーチ ファウンデイション 細菌nadシンテターゼ酵素の阻害剤の合成およびスクリーニング方法、その化合物、ならびに細菌nadシンテターゼ酵素の阻害剤を用いる細菌および微生物感染の治療方法
US6673827B1 (en) 1999-06-29 2004-01-06 The Uab Research Foundation Methods of treating fungal infections with inhibitors of NAD synthetase enzyme
US6861448B2 (en) * 1998-01-14 2005-03-01 Virtual Drug Development, Inc. NAD synthetase inhibitors and uses thereof
WO2006010079A2 (en) * 2004-07-08 2006-01-26 Dr. Reddy's Laboratories Ltd. Process for preparing naratriptan hydrochloride
WO2006010078A2 (en) * 2004-07-08 2006-01-26 Dr. Reddy's Laboratories Ltd. Polymorphic form of naratriptan hydrochloride
CN1315821C (zh) * 2004-12-16 2007-05-16 上海美通生物科技有限公司 制备n-甲基-3-(1-甲基-4-哌啶基)-1,4-吲哚-5-乙硫胺的改进法
US20080015214A1 (en) * 2005-10-24 2008-01-17 Bignan Gilles C 3-piperidin-4-yl-indole orl-1 receptor modulators
WO2009118753A2 (en) * 2008-03-07 2009-10-01 Usv Limited Process for preparation of naratriptan hydrochloride
CN101676283A (zh) * 2008-09-17 2010-03-24 北京德众万全药物技术开发有限公司 一种那拉曲坦的制备方法
JP2013502401A (ja) 2009-08-20 2013-01-24 シプラ・リミテッド ナラトリプタンの合成方法
CN101792411B (zh) * 2010-03-26 2012-05-30 常州晟永光电材料有限公司 一种合成乙磺酰胺的方法
CN103073484B (zh) * 2013-01-28 2014-10-22 山东诚创医药技术开发有限公司 一种甲哌卡因及其光学对映体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE92057T1 (de) * 1987-08-13 1993-08-15 Glaxo Group Ltd Indol-derivate.
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8903036D0 (en) * 1989-02-10 1989-03-30 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
IS1877B (is) 2003-06-20
DE69431759D1 (de) 2003-01-02
HUT75642A (en) 1997-05-28
IS4212A (is) 1995-03-30
US5786473A (en) 1998-07-28
FI961378A0 (fi) 1996-03-26
ZA947516B (en) 1995-06-12
PL313740A1 (en) 1996-07-22
FI961378A (fi) 1996-03-26
DE69431759T2 (de) 2003-07-03
CA2170645A1 (en) 1995-04-06
AU7810194A (en) 1995-04-18
HU9600814D0 (en) 1996-05-28
SK40696A3 (en) 1996-10-02
AP529A (en) 1996-09-09
CA2170645C (en) 2005-11-15
AP9400676A0 (en) 1994-10-31
WO1995009166A1 (en) 1995-04-06
CZ76896A3 (en) 1996-06-12
FI111162B (fi) 2003-06-13
SI0721453T1 (en) 2003-04-30
CN1132509A (zh) 1996-10-02
AU682219B2 (en) 1997-09-25
NO309324B1 (no) 2001-01-15
US5659040A (en) 1997-08-19
DK0721453T3 (da) 2003-03-17
NO961252L (no) 1996-03-28
ES2187534T3 (es) 2003-06-16
EP0721453B1 (en) 2002-11-20
JPH09502991A (ja) 1997-03-25
MY117934A (en) 2004-08-30
PE18195A1 (es) 1995-07-27
PT721453E (pt) 2003-03-31
CN1332166A (zh) 2002-01-23
EP0721453A1 (en) 1996-07-17
PL178456B1 (pl) 2000-05-31
IL111071A0 (en) 1994-11-28
CZ287581B6 (en) 2000-12-13
HU226828B1 (en) 2009-11-30
RU2143428C1 (ru) 1999-12-27
HRP940613A2 (en) 1997-06-30
GB9320115D0 (en) 1993-11-17
HRP940613B1 (en) 2003-10-31
NO961252D0 (no) 1996-03-28
JP3411284B2 (ja) 2003-05-26
CO4290351A1 (es) 1996-04-17
SK282234B6 (sk) 2001-12-03
NZ274159A (en) 1997-09-22
ATE228124T1 (de) 2002-12-15
SG49322A1 (en) 1998-05-18
HK1004218A1 (en) 1998-11-20

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