IL110909A - הכת ה 2\3 הידרט של חומצה s) - 7] - 7( - אמינו - אזאספירו ]4.2[ הפטאן - 5 איל[ - 8 - כלורו - 6 פלואורו - r1, s)] - 21( - 2 - פלואורוציק - Google Patents

הכת ה 2\3 הידרט של חומצה s) - 7] - 7( - אמינו - אזאספירו ]4.2[ הפטאן - 5 איל[ - 8 - כלורו - 6 פלואורו - r1, s)] - 21( - 2 - פלואורוציק

Info

Publication number
IL110909A
IL110909A IL11090994A IL11090994A IL110909A IL 110909 A IL110909 A IL 110909A IL 11090994 A IL11090994 A IL 11090994A IL 11090994 A IL11090994 A IL 11090994A IL 110909 A IL110909 A IL 110909A
Authority
IL
Israel
Prior art keywords
weak
hydrate
heptan
oxo
fluoro
Prior art date
Application number
IL11090994A
Other languages
English (en)
Other versions
IL110909A0 (en
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Priority to IL12391094A priority Critical patent/IL123910A/xx
Publication of IL110909A0 publication Critical patent/IL110909A0/xx
Publication of IL110909A publication Critical patent/IL110909A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Quinoline Compounds (AREA)
IL11090994A 1993-09-10 1994-09-09 הכת ה 2\3 הידרט של חומצה s) - 7] - 7( - אמינו - אזאספירו ]4.2[ הפטאן - 5 איל[ - 8 - כלורו - 6 פלואורו - r1, s)] - 21( - 2 - פלואורוציק IL110909A (he)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL12391094A IL123910A (en) 1993-09-10 1994-09-09 Anhydrate of 7-[7-(s)-amino-5-azaspiro [2.4] heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2s)-2-fluoro-cyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22538093 1993-09-10

Publications (2)

Publication Number Publication Date
IL110909A0 IL110909A0 (en) 1994-11-28
IL110909A true IL110909A (he) 1998-12-06

Family

ID=16828452

Family Applications (2)

Application Number Title Priority Date Filing Date
IL12391094A IL123910A (en) 1993-09-10 1994-09-09 Anhydrate of 7-[7-(s)-amino-5-azaspiro [2.4] heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2s)-2-fluoro-cyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
IL11090994A IL110909A (he) 1993-09-10 1994-09-09 הכת ה 2\3 הידרט של חומצה s) - 7] - 7( - אמינו - אזאספירו ]4.2[ הפטאן - 5 איל[ - 8 - כלורו - 6 פלואורו - r1, s)] - 21( - 2 - פלואורוציק

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL12391094A IL123910A (en) 1993-09-10 1994-09-09 Anhydrate of 7-[7-(s)-amino-5-azaspiro [2.4] heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2s)-2-fluoro-cyclopropyl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Country Status (32)

Country Link
US (1) US5693814A (he)
EP (1) EP0643058B1 (he)
JP (1) JP3793583B2 (he)
KR (1) KR100336247B1 (he)
CN (1) CN1057297C (he)
AT (1) ATE181069T1 (he)
AU (1) AU679094B2 (he)
BG (1) BG61767B1 (he)
CA (1) CA2131761C (he)
CZ (3) CZ284837B6 (he)
DE (1) DE69418953T2 (he)
DK (1) DK0643058T3 (he)
ES (1) ES2136142T3 (he)
FI (1) FI110777B (he)
GE (1) GEP19981355B (he)
GR (1) GR3031012T3 (he)
HR (1) HRP940506B1 (he)
HU (1) HU224970B1 (he)
IL (2) IL123910A (he)
LV (1) LV11322B (he)
MY (1) MY112574A (he)
NO (2) NO307419B1 (he)
NZ (1) NZ264422A (he)
PL (1) PL180163B1 (he)
RU (1) RU2126402C1 (he)
SG (1) SG50492A1 (he)
SI (1) SI9400349B (he)
SK (3) SK283190B6 (he)
TW (1) TW393481B (he)
UA (1) UA41312C2 (he)
YU (1) YU49132B (he)
ZA (1) ZA946853B (he)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE69802692D1 (de) * 1997-06-26 2002-01-10 Dong Wha Pharm Ind Co Ltd Derivate der chinoloncarbonsäure
JP2001300293A (ja) * 2000-04-25 2001-10-30 Nipro Corp 無機無水物または有機無水物の製造法
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
CN102718746B (zh) * 2012-06-18 2014-10-29 南京优科生物医药研究有限公司 西他沙星富马酸盐晶型a和其制药用途
CN103539776B (zh) * 2012-07-16 2016-06-08 深圳信立泰药业股份有限公司 一种西他沙星晶型及其制备方法
CN106749174B (zh) * 2016-12-06 2019-06-18 山东裕欣药业有限公司 一种西他沙星二水合物晶型、制备方法及其组合物片剂

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE203719C (he) * 1907-11-02 1908-10-20
DK170473B1 (da) * 1985-06-20 1995-09-11 Daiichi Seiyaku Co S(-)-pyridobenzoxazinforbindelser
IL90062A (he) * 1988-04-27 1994-10-07 Daiichi Seiyaku Co תולדות החומצה פירידונקרבוקסילית, הכנתן ותכשירי רוקחות המכילים אותן
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
TW208013B (he) * 1990-03-01 1993-06-21 Daiichi Co Ltd
US4994809A (en) * 1990-03-07 1991-02-19 Hughes Aircraft Company Polystatic correlating radar
MY109714A (en) * 1990-10-18 1997-04-30 Daiichi Seiyaku Co Process for preparing 8-chloroquinolone derivatives
CN1065206A (zh) * 1991-04-01 1992-10-14 战永胜 天然中草药防治早泄、淋病双效药液制法
WO1993025545A1 (en) * 1992-06-09 1993-12-23 Korea Research Institute Of Chemical Technology Novel quinoline derivatives and processes for preparing the same

Also Published As

Publication number Publication date
NO992513L (no) 1995-03-13
FI110777B (fi) 2003-03-31
IL123910A (en) 1999-06-20
SK283189B6 (sk) 2003-03-04
BG99035A (bg) 1995-05-31
SI9400349B (sl) 2000-08-31
IL110909A0 (en) 1994-11-28
TW393481B (en) 2000-06-11
CZ21598A3 (cs) 1999-02-17
DE69418953D1 (de) 1999-07-15
HUT68541A (en) 1995-06-28
NO943313D0 (no) 1994-09-08
CN1106006A (zh) 1995-08-02
AU7286294A (en) 1995-03-23
JP3793583B2 (ja) 2006-07-05
SK283188B6 (sk) 2003-03-04
NO943313L (no) 1995-03-13
HU9402597D0 (en) 1994-11-28
NO307419B1 (no) 2000-04-03
KR100336247B1 (ko) 2005-08-11
CZ284837B6 (cs) 1999-03-17
MY112574A (en) 2001-07-31
NO992513D0 (no) 1999-05-25
JPH07126266A (ja) 1995-05-16
CZ217694A3 (en) 1995-03-15
YU49132B (sh) 2004-03-12
SK107694A3 (en) 1995-05-10
CZ284737B6 (cs) 1999-02-17
EP0643058A1 (en) 1995-03-15
RU94032286A (ru) 1996-08-10
ATE181069T1 (de) 1999-06-15
CA2131761C (en) 2002-04-30
FI944174A (fi) 1995-03-11
US5693814A (en) 1997-12-02
EP0643058B1 (en) 1999-06-09
GR3031012T3 (en) 1999-12-31
NZ264422A (en) 1995-07-26
KR950008506A (ko) 1995-04-17
FI944174A0 (fi) 1994-09-09
CA2131761A1 (en) 1995-03-11
CZ284738B6 (cs) 1999-02-17
HU224970B1 (en) 2006-04-28
GEP19981355B (en) 1998-08-25
ZA946853B (en) 1995-04-24
SK283190B6 (sk) 2003-03-04
SI9400349A (en) 1995-04-30
HRP940506B1 (en) 2000-10-31
AU679094B2 (en) 1997-06-19
RU2126402C1 (ru) 1999-02-20
SG50492A1 (en) 1998-07-20
PL180163B1 (pl) 2000-12-29
ES2136142T3 (es) 1999-11-16
DK0643058T3 (da) 1999-11-15
BG61767B1 (bg) 1998-05-29
HRP940506A2 (en) 1997-04-30
PL304989A1 (en) 1995-03-20
LV11322B (en) 1996-10-20
DE69418953T2 (de) 2000-01-13
CN1057297C (zh) 2000-10-11
NO307753B1 (no) 2000-05-22
CZ21498A3 (cs) 1999-02-17
UA41312C2 (uk) 2001-09-17
LV11322A (lv) 1996-06-20
YU53694A (sh) 1997-03-07

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MM9K Patent not in force due to non-payment of renewal fees