ES2136142T3 - Cristales de un compuesto antimicrobiano. - Google Patents

Cristales de un compuesto antimicrobiano.

Info

Publication number
ES2136142T3
ES2136142T3 ES94114235T ES94114235T ES2136142T3 ES 2136142 T3 ES2136142 T3 ES 2136142T3 ES 94114235 T ES94114235 T ES 94114235T ES 94114235 T ES94114235 T ES 94114235T ES 2136142 T3 ES2136142 T3 ES 2136142T3
Authority
ES
Spain
Prior art keywords
crystals
hydrate
antimicrobial compound
compound
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94114235T
Other languages
English (en)
Inventor
Youichi Kimura
Katsuhiro Kawakami
Norimasa Mikata
Keiji Uchiyama
Tazuo Uemura
Yusuke Yukimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2136142T3 publication Critical patent/ES2136142T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SE PRESENTA UN METODO PARA OBTENER SELECTIVAMENTE BIEN: 1/2 HIDRATO, UN HIDRATO, O 3/2 HIDRATO DEL ACIDO 7-[7-(S)-AMINO-5AZASPIRO[2.4]HEPTAN-5-IL]-8-CLORO-6-FLUORO-1-[(1R,2S)-2FLUOROCICLOPROPIL]-4-OXO-1,4-DIHIDROQUINOLINA-3-CARBOXILICO, QUE COMPRENDE EL TRATAMIENTO DEL COMPUESTO EN UN SOLVENTE ACUOSO O AGUA O LA RECRISTALIZACION DEL COMPUESTO DESDE UN SOLVENTE ACUOSO O AGUA.
ES94114235T 1993-09-10 1994-09-09 Cristales de un compuesto antimicrobiano. Expired - Lifetime ES2136142T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22538093 1993-09-10

Publications (1)

Publication Number Publication Date
ES2136142T3 true ES2136142T3 (es) 1999-11-16

Family

ID=16828452

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94114235T Expired - Lifetime ES2136142T3 (es) 1993-09-10 1994-09-09 Cristales de un compuesto antimicrobiano.

Country Status (32)

Country Link
US (1) US5693814A (es)
EP (1) EP0643058B1 (es)
JP (1) JP3793583B2 (es)
KR (1) KR100336247B1 (es)
CN (1) CN1057297C (es)
AT (1) ATE181069T1 (es)
AU (1) AU679094B2 (es)
BG (1) BG61767B1 (es)
CA (1) CA2131761C (es)
CZ (3) CZ21598A3 (es)
DE (1) DE69418953T2 (es)
DK (1) DK0643058T3 (es)
ES (1) ES2136142T3 (es)
FI (1) FI110777B (es)
GE (1) GEP19981355B (es)
GR (1) GR3031012T3 (es)
HR (1) HRP940506B1 (es)
HU (1) HU224970B1 (es)
IL (2) IL123910A (es)
LV (1) LV11322B (es)
MY (1) MY112574A (es)
NO (2) NO307419B1 (es)
NZ (1) NZ264422A (es)
PL (1) PL180163B1 (es)
RU (1) RU2126402C1 (es)
SG (1) SG50492A1 (es)
SI (1) SI9400349B (es)
SK (3) SK283189B6 (es)
TW (1) TW393481B (es)
UA (1) UA41312C2 (es)
YU (1) YU49132B (es)
ZA (1) ZA946853B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
JP3280388B2 (ja) * 1997-06-26 2002-05-13 ドング ホワ ファーマシューチカル インダストリアル カンパニー，リミテッド キノロンカルボン酸誘導体
JP2001300293A (ja) * 2000-04-25 2001-10-30 Nipro Corp 無機無水物または有機無水物の製造法
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
CN102718746B (zh) * 2012-06-18 2014-10-29 南京优科生物医药研究有限公司 西他沙星富马酸盐晶型a和其制药用途
CN103539776B (zh) * 2012-07-16 2016-06-08 深圳信立泰药业股份有限公司 一种西他沙星晶型及其制备方法
CN106749174B (zh) * 2016-12-06 2019-06-18 山东裕欣药业有限公司 一种西他沙星二水合物晶型、制备方法及其组合物片剂

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE203719C (es) * 1907-11-02 1908-10-20
NO166131C (no) * 1985-06-20 1991-06-05 Daiichi Seiyaku Co Analogifremgangsmaate for fremstilling av s(-)-pyridobenzoksazinforbindelser.
MY105136A (en) * 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
TW208013B (es) * 1990-03-01 1993-06-21 Daiichi Co Ltd
US4994809A (en) * 1990-03-07 1991-02-19 Hughes Aircraft Company Polystatic correlating radar
MY109714A (en) * 1990-10-18 1997-04-30 Daiichi Seiyaku Co Process for preparing 8-chloroquinolone derivatives
CN1065206A (zh) * 1991-04-01 1992-10-14 战永胜 天然中草药防治早泄、淋病双效药液制法
WO1993025545A1 (en) * 1992-06-09 1993-12-23 Korea Research Institute Of Chemical Technology Novel quinoline derivatives and processes for preparing the same

Also Published As

Publication number Publication date
US5693814A (en) 1997-12-02
GR3031012T3 (en) 1999-12-31
UA41312C2 (uk) 2001-09-17
FI110777B (fi) 2003-03-31
NO943313D0 (no) 1994-09-08
SK283188B6 (sk) 2003-03-04
PL304989A1 (en) 1995-03-20
HRP940506B1 (en) 2000-10-31
MY112574A (en) 2001-07-31
HU9402597D0 (en) 1994-11-28
DK0643058T3 (da) 1999-11-15
EP0643058A1 (en) 1995-03-15
NO992513D0 (no) 1999-05-25
JPH07126266A (ja) 1995-05-16
ZA946853B (en) 1995-04-24
HRP940506A2 (en) 1997-04-30
CZ284837B6 (cs) 1999-03-17
BG99035A (bg) 1995-05-31
YU49132B (sh) 2004-03-12
RU2126402C1 (ru) 1999-02-20
CN1057297C (zh) 2000-10-11
NO943313L (no) 1995-03-13
CZ217694A3 (en) 1995-03-15
HUT68541A (en) 1995-06-28
DE69418953D1 (de) 1999-07-15
SI9400349A (en) 1995-04-30
TW393481B (en) 2000-06-11
IL110909A0 (en) 1994-11-28
CA2131761A1 (en) 1995-03-11
SK283190B6 (sk) 2003-03-04
DE69418953T2 (de) 2000-01-13
FI944174A0 (fi) 1994-09-09
LV11322A (lv) 1996-06-20
KR100336247B1 (ko) 2005-08-11
AU679094B2 (en) 1997-06-19
KR950008506A (ko) 1995-04-17
CN1106006A (zh) 1995-08-02
NO307753B1 (no) 2000-05-22
NO307419B1 (no) 2000-04-03
IL110909A (en) 1998-12-06
BG61767B1 (bg) 1998-05-29
RU94032286A (ru) 1996-08-10
CZ21498A3 (cs) 1999-02-17
CZ284737B6 (cs) 1999-02-17
CZ284738B6 (cs) 1999-02-17
SI9400349B (sl) 2000-08-31
FI944174L (fi) 1995-03-11
NO992513L (no) 1995-03-13
EP0643058B1 (en) 1999-06-09
CZ21598A3 (cs) 1999-02-17
PL180163B1 (pl) 2000-12-29
GEP19981355B (en) 1998-08-25
SK107694A3 (en) 1995-05-10
AU7286294A (en) 1995-03-23
SG50492A1 (en) 1998-07-20
YU53694A (sh) 1997-03-07
SK283189B6 (sk) 2003-03-04
IL123910A (en) 1999-06-20
ATE181069T1 (de) 1999-06-15
JP3793583B2 (ja) 2006-07-05
LV11322B (en) 1996-10-20
HU224970B1 (en) 2006-04-28
NZ264422A (en) 1995-07-26
CA2131761C (en) 2002-04-30

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