CO4340619A1 - Derivados cristalinos del acido n-acetil neuramico y procesos para su preparacion - Google Patents

Derivados cristalinos del acido n-acetil neuramico y procesos para su preparacion

Info

Publication number
CO4340619A1
CO4340619A1 CO94056728A CO94056728A CO4340619A1 CO 4340619 A1 CO4340619 A1 CO 4340619A1 CO 94056728 A CO94056728 A CO 94056728A CO 94056728 A CO94056728 A CO 94056728A CO 4340619 A1 CO4340619 A1 CO 4340619A1
Authority
CO
Colombia
Prior art keywords
tetradesoxi
galacto
guanidino
acid
glicero
Prior art date
Application number
CO94056728A
Other languages
English (en)
Inventor
Christopher Williamson
William James White
Patel Vipulkumar
Original Assignee
Biota Scient Management
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scient Management filed Critical Biota Scient Management
Publication of CO4340619A1 publication Critical patent/CO4340619A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

REIVINDICACION NUMERO ACIDO 5-ACETAMIDO-2,3,4,5-TETRADESOXI-4-GUANIDINO- D-GLICERO-D-GALACTO-NON-2-ENOPIRANOSONICO, CARAC- TERIZADO PORQUE ESTA EN FORMA CRISTALINA". REIVINDICACION NUMERO ACIDO 5-ACETAMIDO-2,3,4,5-TETRADESOXI-4-GUANIDINO- D-GLICERO-D-GALACTO-NON2-ENOPIRANOSONICO, CARAC- TERIZADO PORQUE ESTA EN LA FORMA DE CRISTALES QUE TIENEN UNA BAJA RELACION ENTRE DIMENSIONES". REIVINDICACION NUMERO ACODP 5-ACETAMIDO-2,3,4,5-TETRADESOXI-4-GUANIDINO- D-GLICERO-D-GALACTO-NON-2-ENOPIRANOSONICO, CARAC- TERIZADO PORQUE ESTA EN LA FORMA DE CRISTALES QUE TIENEN UNA ALTA RELACION ENTRE DIMENSIONES". REIVINDICACION NUMERO 1UN METODO PARA LA PREPARACION DEL ACIDO 5-ACETA- MIDO-2,3,4,5-TETRADESOXI-4-GUANIDINO-D-GLICERO-D- GALACTO-NON-2-ENOPIRANOSONICOEN FORMA CRISTALINA, EL METODO ESTA CARACTERIZADO PORQUE COMPRENDE LA CRISTALIZACION DEL ACIDO 5-ACETAMIDO-2,3,4,5- TETRADESOXI-4-GUANIDINO-D-GLICERO-D-GALACTO-NON-2 ENOPIRANOSONICO A PARTIR DE LA SOLUCION ACUOSA". REIVINDICACION NUMERO UNA FORMULACION FARMACEUTICA CARACTERIZADA PORQUE COMPRENDE ACIDO 5-ACETAMIDO-2,3,4,5-TETRADESOXI-4- GUANIDINO-D-GLICERO-D-GALACTO-NON-2-ENOPIRANOSONI- CO EN FORMA CRISTALINA Y UN PORTADOR FARMACEUTI- CAMENTE ACEPTABLE PARA EL MISMO".
CO94056728A 1993-12-17 1994-12-15 Derivados cristalinos del acido n-acetil neuramico y procesos para su preparacion CO4340619A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939325841A GB9325841D0 (en) 1993-12-17 1993-12-17 Chemical compounds

Publications (1)

Publication Number Publication Date
CO4340619A1 true CO4340619A1 (es) 1996-07-30

Family

ID=10746778

Family Applications (1)

Application Number Title Priority Date Filing Date
CO94056728A CO4340619A1 (es) 1993-12-17 1994-12-15 Derivados cristalinos del acido n-acetil neuramico y procesos para su preparacion

Country Status (44)

Country Link
US (2) US6294572B1 (es)
EP (1) EP0734382B1 (es)
JP (1) JP3317972B2 (es)
KR (1) KR100403256B1 (es)
CN (2) CN1502621A (es)
AP (2) AP9600810A0 (es)
AT (1) ATE199255T1 (es)
BG (1) BG63338B1 (es)
BR (2) BR9408340A (es)
CA (1) CA2177990C (es)
CO (1) CO4340619A1 (es)
CZ (1) CZ289234B6 (es)
DE (1) DE69426726T2 (es)
DK (1) DK0734382T3 (es)
EE (1) EE03353B1 (es)
EG (1) EG20597A (es)
ES (1) ES2155517T3 (es)
FI (1) FI120453B (es)
GB (1) GB9325841D0 (es)
GR (1) GR3035681T3 (es)
HK (1) HK1014187A1 (es)
HR (1) HRP941001B1 (es)
HU (1) HU221971B1 (es)
IL (1) IL112011A (es)
IS (1) IS4240A (es)
MA (1) MA23396A1 (es)
MY (1) MY116221A (es)
NO (1) NO314759B1 (es)
NZ (1) NZ277789A (es)
OA (2) OA10325A (es)
PE (1) PE31095A1 (es)
PL (1) PL186384B1 (es)
PT (1) PT734382E (es)
RO (1) RO114792B1 (es)
RU (1) RU2134690C1 (es)
SA (1) SA94150417B1 (es)
SG (1) SG46669A1 (es)
SI (1) SI0734382T1 (es)
SK (1) SK282972B6 (es)
SV (1) SV1994000076A (es)
TW (1) TW452577B (es)
UA (1) UA46723C2 (es)
WO (1) WO1995016680A1 (es)
ZA (1) ZA9410003B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9325841D0 (en) * 1993-12-17 1994-02-23 Glaxo Group Ltd Chemical compounds
US5866601A (en) * 1995-02-27 1999-02-02 Gilead Sciences, Inc. Carbocyclic compounds
DE69607704T2 (de) 1995-02-27 2000-12-28 Gilead Sciences, Inc. Neue selektive inhibitoren viraler oder bakterieller neuraminidasen
US5763483A (en) * 1995-12-29 1998-06-09 Gilead Sciences, Inc. Carbocyclic compounds
US6340702B1 (en) 1996-07-22 2002-01-22 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
PT823428E (pt) * 1996-07-22 2002-04-29 Sankyo Co Derivados do acido neuraminico sua preparacao e sua utilizacao em medicina
US6451766B1 (en) 1996-07-22 2002-09-17 Sankyo Company, Limited Neuraminic acid derivatives, their preparation and their medical use
US6518438B2 (en) 1996-08-23 2003-02-11 Gilead Sciences, Inc. Preparation of cyclohexene carboxylate derivatives
US5859284A (en) * 1996-08-23 1999-01-12 Gilead Sciences, Inc. Preparation of carbocyclic compounds
US5994377A (en) * 1996-10-21 1999-11-30 Gilead Sciences, Inc. Piperidine compounds
US5886213A (en) * 1997-08-22 1999-03-23 Gilead Sciences, Inc. Preparation of carbocyclic compounds
TW480247B (en) * 1997-12-12 2002-03-21 Gilead Sciences Inc Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
TWI291462B (en) 2000-04-25 2007-12-21 Daiichi Sankyo Co Ltd Hydrate crystal of neuraminic acid compound
US20080063722A1 (en) * 2006-09-08 2008-03-13 Advanced Inhalation Research, Inc. Composition of a Spray-Dried Powder for Pulmonary Delivery of a Long Acting Neuraminidase Inhibitor (LANI)
CA2859296C (en) * 2011-12-16 2016-10-11 Daiichi Sankyo Company, Limited Method for manufacturing neuraminic acid derivatives
CN109232677B (zh) * 2018-10-18 2021-12-28 中国科学院合肥物质科学研究院 一种使n-乙酰神经氨酸水合物转化为n-乙酰神经氨酸的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP249A (en) * 1990-04-24 1993-03-17 Biota Scient Management Pty Ltd Anti-viral compounds.
AU659501B2 (en) * 1991-10-23 1995-05-18 Biota Scientific Management Pty Ltd Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-D-neuraminic acid
US5639786A (en) 1992-12-04 1997-06-17 Biota Scientific Management, Pty., Ltd. Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of α-D-neuraninic acid
GB9325841D0 (en) * 1993-12-17 1994-02-23 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
CZ169396A3 (en) 1996-11-13
NZ277789A (en) 1999-04-29
EP0734382A1 (en) 1996-10-02
SI0734382T1 (en) 2001-08-31
PT734382E (pt) 2001-06-29
BR1100548KB1 (pt) 2011-11-01
ATE199255T1 (de) 2001-03-15
FI962464A0 (fi) 1996-06-13
GR3035681T3 (en) 2001-06-29
HU221971B1 (hu) 2003-03-28
US6294572B1 (en) 2001-09-25
EP0734382B1 (en) 2001-02-21
IL112011A (en) 1998-08-16
HU9601642D0 (en) 1996-08-28
NO962545L (no) 1996-06-14
AU689185B2 (en) 1998-03-26
PE31095A1 (es) 1995-10-18
AP9400705A0 (en) 1995-01-31
CN1142820A (zh) 1997-02-12
HUT74938A (en) 1997-03-28
OA10325A (en) 1997-10-07
DK0734382T3 (da) 2001-03-19
FI962464A (fi) 1996-06-13
HRP941001A2 (en) 1997-06-30
NO314759B1 (no) 2003-05-19
SV1994000076A (es) 1995-10-26
HK1014187A1 (en) 1999-09-24
BR9408340A (pt) 1997-08-19
BG100709A (bg) 1997-01-31
TW452577B (en) 2001-09-01
BG63338B1 (bg) 2001-10-31
HRP941001B1 (en) 2001-06-30
CN1502621A (zh) 2004-06-09
DE69426726D1 (de) 2001-03-29
SK78596A3 (en) 1997-03-05
DE69426726T2 (de) 2001-06-21
SG46669A1 (en) 1998-02-20
NO962545D0 (no) 1996-06-14
EE03353B1 (et) 2001-02-15
EG20597A (en) 1999-09-30
IS4240A (is) 1995-06-18
SK282972B6 (sk) 2003-01-09
FI120453B (fi) 2009-10-30
ZA9410003B (en) 1995-07-25
OA11275A (en) 2002-11-20
RU2134690C1 (ru) 1999-08-20
AU1314495A (en) 1995-07-03
CZ289234B6 (cs) 2001-12-12
JP3317972B2 (ja) 2002-08-26
CA2177990C (en) 2000-04-25
PL315055A1 (en) 1996-09-30
AP9600810A0 (en) 1996-07-31
ES2155517T3 (es) 2001-05-16
IL112011A0 (en) 1995-03-15
AP541A (en) 1996-10-01
US20020037865A1 (en) 2002-03-28
KR100403256B1 (ko) 2004-04-30
SA94150417B1 (ar) 2005-12-18
CN1132829C (zh) 2003-12-31
PL186384B1 (pl) 2004-01-30
GB9325841D0 (en) 1994-02-23
MY116221A (en) 2003-12-31
RO114792B1 (ro) 1999-07-30
JPH09506601A (ja) 1997-06-30
CA2177990A1 (en) 1995-06-22
MA23396A1 (fr) 1995-07-01
UA46723C2 (uk) 2002-06-17
WO1995016680A1 (en) 1995-06-22

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