MX171861B - Composiciones medicinales acuosas que contienen un factor de crecimiento poli-peptidico y el metodo para estabilizar las mismas - Google Patents

Composiciones medicinales acuosas que contienen un factor de crecimiento poli-peptidico y el metodo para estabilizar las mismas

Info

Publication number
MX171861B
MX171861B MX915187A MX915187A MX171861B MX 171861 B MX171861 B MX 171861B MX 915187 A MX915187 A MX 915187A MX 915187 A MX915187 A MX 915187A MX 171861 B MX171861 B MX 171861B
Authority
MX
Mexico
Prior art keywords
stabilize
poly
growth factor
compositions containing
medicinal compositions
Prior art date
Application number
MX915187A
Other languages
English (en)
Inventor
Amy L Finkenaur
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/927,627 external-priority patent/US4717717A/en
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of MX171861B publication Critical patent/MX171861B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/20Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A23C9/206Colostrum; Human milk
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1808Epidermal growth factor [EGF] urogastrone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/005Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Immunology (AREA)
  • Polymers & Plastics (AREA)
  • Vascular Medicine (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Dairy Products (AREA)
MX915187A 1986-11-05 1987-11-05 Composiciones medicinales acuosas que contienen un factor de crecimiento poli-peptidico y el metodo para estabilizar las mismas MX171861B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/927,627 US4717717A (en) 1986-11-05 1986-11-05 Stabilized compositions containing epidermal growth factor
US9645587A 1987-09-18 1987-09-18

Publications (1)

Publication Number Publication Date
MX171861B true MX171861B (es) 1993-11-22

Family

ID=26791728

Family Applications (1)

Application Number Title Priority Date Filing Date
MX915187A MX171861B (es) 1986-11-05 1987-11-05 Composiciones medicinales acuosas que contienen un factor de crecimiento poli-peptidico y el metodo para estabilizar las mismas

Country Status (13)

Country Link
EP (1) EP0267015B1 (es)
JP (2) JP2942227B2 (es)
KR (1) KR880005935A (es)
AU (1) AU614941B2 (es)
CA (1) CA1322328C (es)
DE (1) DE3781509T2 (es)
DK (1) DK579787A (es)
ES (1) ES2044952T3 (es)
GR (1) GR871700B (es)
MX (1) MX171861B (es)
NZ (2) NZ222413A (es)
PT (1) PT86075B (es)
SG (1) SG104292G (es)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019559A (en) * 1986-11-14 1991-05-28 President And Fellows Of Harvard College Wound healing using PDGF and IGF-II
US5226912A (en) 1987-08-26 1993-07-13 United States Surgical Corporation Combined surgical needle-braided suture device
US5366081A (en) 1987-08-26 1994-11-22 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5472702A (en) * 1987-08-26 1995-12-05 United States Surgical Corporation Sterilization of growth factors
US5306289A (en) * 1987-08-26 1994-04-26 United States Surgical Corporation Braided suture of improved characteristics
US5222978A (en) 1987-08-26 1993-06-29 United States Surgical Corporation Packaged synthetic absorbable surgical elements
US5705485A (en) * 1987-09-18 1998-01-06 Ethicon, Inc. Gel formulations containing growth factors
US4983581A (en) * 1988-05-20 1991-01-08 Institute Of Molecular Biology, Inc. Wound healing composition of IGF-I and TGF-β
AU614137B2 (en) * 1988-06-06 1991-08-22 Takeda Chemical Industries Ltd. Stabilized fgf composition and production thereof
CA1330391C (en) * 1988-07-19 1994-06-28 Matthew E. Hermes Method for improving the storage stability of a polymeric article susceptible to hydrolic degradation and resulting article
US5034375A (en) * 1988-08-10 1991-07-23 Institute Of Molecular Biology, Inc. Process of wound healing using PDGF and EGF
GB8823649D0 (en) * 1988-10-07 1988-11-16 Geistlich Soehne Ag Chemical compounds
US5013714A (en) * 1988-12-15 1991-05-07 Lindstrom Richard L Viscoelastic solution
US5693625A (en) * 1989-03-09 1997-12-02 Therapeutiques Substitutives Method of regenerating cells and tissues using functionalized dextrans
FR2644066B1 (fr) * 1989-03-09 1994-05-13 Therapeutiques Substitutives Compositions stabilisees comprenant des fgfs, leur procede d'obtention et leurs applications therapeutiques, chirurgicales et cosmetologiques
CA2020654A1 (en) * 1989-07-07 1991-01-08 Yohko Akiyama Stabilized fgf composition and production thereof
US5246104A (en) * 1989-08-01 1993-09-21 United States Surgical Corporation Molded suture retainer
US5359831A (en) 1989-08-01 1994-11-01 United States Surgical Corporation Molded suture retainer
US5422340A (en) * 1989-09-01 1995-06-06 Ammann; Arthur J. TGF-βformulation for inducing bone growth
IT1240683B (it) * 1990-04-26 1993-12-17 Zambon Spa Composizione farmaceutica contenente egf
DE69133087T2 (de) * 1990-05-30 2003-04-03 Inst Molecular Biology Inc Kombination aus IGF-I und TGF-beta zur Knochenregenerierung
US5681814A (en) * 1990-06-07 1997-10-28 Genentech, Inc. Formulated IGF-I Composition
US5374620A (en) * 1990-06-07 1994-12-20 Genentech, Inc. Growth-promoting composition and its use
GB9014871D0 (en) * 1990-07-05 1990-08-22 Erba Carlo Spa Drug delivery system for administering growth factor
NZ234439A (en) * 1990-07-10 1997-08-22 Pharmacia & Upjohn Ab Use of igf-1 to reduce fetal growth retardation in non human mammals
US5714458A (en) * 1990-07-18 1998-02-03 Farmitalia Carlo Erba S.R.L. Stable pharmaceutical compositions containing a fibroblast growth factor
GB9015824D0 (en) * 1990-07-18 1990-09-05 Erba Carlo Spa Stable pharmaceutical compositions containing a fibroblast growth factor
CA2055811A1 (en) * 1991-01-11 1992-07-12 Ross R. Muth Sterilization of growth factors
CA2059245C (en) * 1991-02-08 2004-07-06 Michael P. Chesterfield Method and apparatus for calendering and coating/filling sutures
US5605938A (en) * 1991-05-31 1997-02-25 Gliatech, Inc. Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate
US5705178A (en) * 1991-05-31 1998-01-06 Gliatech, Inc. Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers
AU3062392A (en) * 1991-11-04 1993-06-07 Novo Nordisk A/S Pdgf gel formulation
US5192743A (en) * 1992-01-16 1993-03-09 Genentech, Inc. Reconstitutable lyophilized protein formulation
US5348941A (en) * 1992-04-01 1994-09-20 Merck & Co., Inc. Stabilizers for fibroblast growth factors
GB9210574D0 (en) * 1992-05-18 1992-07-01 Ca Nat Research Council Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications
CA2104418A1 (en) * 1992-08-24 1994-02-25 Miguel A. Maestro Method of preparing hydrindane compounds and hydrindane-related compounds
CU22405A1 (es) * 1993-07-05 1996-01-31 Cigb Composicion cosmetica para el cuidado de la piel
US6277828B1 (en) * 1993-08-20 2001-08-21 Syntex (U.S.A.) Inc. Pharmaceutical formulations of nerve growth factor
DE4438015A1 (de) * 1994-10-25 1996-05-02 Boehringer Mannheim Gmbh Epithelzellenhaltiges Biomaterial und dessen Verwendung als Transplantat
US5904716A (en) * 1995-04-26 1999-05-18 Gendler; El Method for reconstituting cartilage tissue using demineralized bone and product thereof
US6572820B2 (en) 1996-02-05 2003-06-03 Asahi Medical Co., Ltd. Sterilization-protecting agent and sterilization method
AU2063197A (en) * 1996-03-04 1997-09-22 Massachusetts Institute Of Technology Materials and methods for enhancing cellular internalization
EP0950663B1 (en) * 1997-08-01 2007-11-07 Toray Industries, Inc. Method for stabilizing useful proteins and useful protein compositions
IT1298758B1 (it) * 1998-03-19 2000-02-02 Angelini Ricerche Spa Soluzione umettante e lubrificante per uso oftalmico
NZ511072A (en) 1998-10-05 2004-03-26 Penn State Res Found Method for enhancing receptor-mediated cellular internalization using a composition of an active agent and a viscous material and an enhancer
GB2344519B (en) * 1998-12-07 2004-05-19 Johnson & Johnson Medical Ltd Sterile therapeutic compositions
US20030228288A1 (en) 1999-10-15 2003-12-11 Scarborough Nelson L. Volume maintaining osteoinductive/osteoconductive compositions
KR100366439B1 (ko) * 2000-02-21 2003-01-09 주식회사 대웅 상피세포 성장인자를 유효성분으로 하는 안정한 약제학적조성물
US6309454B1 (en) 2000-05-12 2001-10-30 Johnson & Johnson Medical Limited Freeze-dried composite materials and processes for the production thereof
US9387094B2 (en) 2000-07-19 2016-07-12 Warsaw Orthopedic, Inc. Osteoimplant and method of making same
KR100426223B1 (ko) * 2000-10-27 2004-04-08 한건 수용성 펩타이드 약물의 건조 리포좀 조성물 및 그의 제조방법
US7323193B2 (en) 2001-12-14 2008-01-29 Osteotech, Inc. Method of making demineralized bone particles
WO2002060315A2 (en) 2001-01-30 2002-08-08 Orthogene, Inc. Compositions and methods for the treatment and repair of defects or lesions in articular cartilage using synovial-derived tissue or cells
EP2213308A1 (en) * 2001-08-10 2010-08-04 Toray Industries Inc. Eyedrop comprising agar
JP2005505351A (ja) 2001-10-12 2005-02-24 オステオテック インコーポレーテッド 改善された骨移植片
CN1582167A (zh) * 2001-11-02 2005-02-16 积水化学工业株式会社 细胞因子诱导材料和细胞因子诱导装置
US20030109820A1 (en) * 2001-12-07 2003-06-12 Gross T. Daniel Hemostatic agent delivery system
CA2528086C (en) 2003-06-11 2013-01-08 Osteotech, Inc. Osteoimplants and methods for their manufacture
AU2005235800B2 (en) * 2004-04-23 2011-08-04 Expedeon Limited Methods and kits for stabilising, protecting and solubilising proteins
JP2008543877A (ja) 2005-06-17 2008-12-04 リジェナークス・バイオファーマスーティカルズ・インコーポレイテッド Lkktetおよび/またはlkktnt組成物および組織の悪化、傷害または損傷を処置または予防するための方法
KR20080028942A (ko) * 2005-07-20 2008-04-02 교와 메덱스 가부시키가이샤 생체 시료 중의 펩티드의 안정화 방법
WO2007056671A1 (en) 2005-11-02 2007-05-18 Osteotech, Inc. Hemostatic bone graft
KR100748390B1 (ko) * 2005-11-14 2007-08-10 주식회사 대웅 상피세포성장인자를 포함하는 상처치료용 서방성 필름 제형
KR100784134B1 (ko) * 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
JP2008200195A (ja) * 2007-02-19 2008-09-04 Daitaro Fukuoka 形成施術用糸およびこれを用いた形成施術方法
US20090192554A1 (en) 2008-01-29 2009-07-30 Confluent Surgical, Inc. Bioabsorbable block copolymer
AU2009308191A1 (en) 2008-10-24 2010-04-29 Warsaw Orthopedic, Inc. Compositions and methods for promoting bone formation
CN102389392B (zh) * 2011-11-02 2012-10-24 珠海亿胜生物制药有限公司 重组牛碱性成纤维细胞生长因子眼用凝胶
WO2013131040A1 (en) 2012-03-01 2013-09-06 Firststring Research, Inc. Topical gels containing alpha connexin c-terminal (act) peptides
CN104740677B (zh) * 2015-04-23 2017-06-06 广西达庆生物科技股份有限公司 一种皮肤医用修复敷料及其制备方法
CN106720379A (zh) * 2016-12-05 2017-05-31 中国科学院兰州化学物理研究所 一种驼血多肽奶片及其制备方法
US11241480B2 (en) * 2017-01-26 2022-02-08 Washington University Methods for modulation of dietary and microbial exposure with compositions comprising an EGFR ligand
EP3902573A4 (en) * 2018-12-28 2022-08-24 Excel Med, LLC BIOLOGICAL SCAFFOLDING AND PROCESS FOR THE PRODUCTION THEREOF
CN110075054A (zh) * 2019-06-06 2019-08-02 山东天源人乳库科技发展有限公司 一种来源于人乳的人源性生长因子修复制剂及其制备方法
US20230031385A1 (en) * 2021-07-20 2023-02-02 National Health Research Institutes Storage media for preservation of corneal tissue

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179497A (en) * 1973-12-17 1979-12-18 Merck & Co., Inc. Solid state ophthalmic medication
DE3380839D1 (en) * 1983-11-02 1989-12-21 J C R Kabushiki Kaisha Also Kn Ophthalmic preparations
JPS60258125A (ja) * 1984-06-06 1985-12-20 Hayashibara Biochem Lab Inc 蛋白性生理活性物質を含有する水溶性乾燥物
EP0193917A3 (en) * 1985-03-06 1987-09-23 American Cyanamid Company Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration

Also Published As

Publication number Publication date
EP0267015A3 (en) 1990-01-17
JPH11255663A (ja) 1999-09-21
SG104292G (en) 1992-12-24
DE3781509T2 (de) 1993-01-07
KR880005935A (ko) 1988-07-21
GR871700B (en) 1988-03-04
DE3781509D1 (de) 1992-10-08
PT86075A (en) 1987-12-01
AU8064187A (en) 1988-05-12
AU614941B2 (en) 1991-09-19
JP2988925B2 (ja) 1999-12-13
DK579787A (da) 1988-05-06
NZ235556A (en) 1991-06-25
DK579787D0 (da) 1987-11-04
JP2942227B2 (ja) 1999-08-30
NZ222413A (en) 1991-06-25
PT86075B (pt) 1990-11-07
EP0267015A2 (en) 1988-05-11
CA1322328C (en) 1993-09-21
EP0267015B1 (en) 1992-09-02
JPS63152324A (ja) 1988-06-24
ES2044952T3 (es) 1994-01-16
JPH10167980A (ja) 1998-06-23

Similar Documents

Publication Publication Date Title
MX171861B (es) Composiciones medicinales acuosas que contienen un factor de crecimiento poli-peptidico y el metodo para estabilizar las mismas
PT83013B (pt) Processo para a preparacao de hidroxialquilxantinas terciarias, e de composicoes farmaceuticas que as contem
PT83143B (pt) Processo para a preparacao de 1,4-dihidro-piridinas 2-substituidas com tiometilo e de composicoes farmaceuticas que as contem
PT84078B (pt) Processo para a preparacao de alquilaminas diarilalquil-substituidas e de medicamentos que as contem
PT89094A (pt) Processo para a preparacao de 1-aril-3-quinolina-e 1-aril-3-isoquinolina-carboxamidas e de composicoes farmaceuticas que as contem
PT80231B (pt) Processo para a preparacao de derivados de nitrometileno com efeito insecticida
ES549639A0 (es) Dispositivo osmotico para la administracion controlada de unagente benefico a un ambiente de utilizacion
BR8800694A (pt) Metodo para produzir engrenagens anulares
BR8602579A (pt) Metodo para produzir uma linha de irrigacao por gotejamento e emissor para linha de irrigacao por gotejamento
AR240896A1 (es) Articulo de vidro-ceramica altamente cristalino y metodo para prepa-rarlo.
PT86801A (pt) Utilizacao de n-cianoisotioureias para preparar composicoes uteis no combate a pragas
PT88203A (pt) Processo para a preparacao de quinolonas e de composicoes farmaceuticas que as contem
BR8901146A (pt) Pa para helice carenada
PT83397B (pt) Processo para a preparacao de aril-piridinas e de composicoes insecticidas que as contem
ES551439A0 (es) Procedimiento para preparar 4h-1-benzopiran-4-onas
BR8603942A (pt) Processo para aumentar a estabilidade de uma formulacao aquosa de um inseticida piretroide
BR8903911A (pt) Processo para a preparacao de uma emulsao transparente inseticida
PT84358B (pt) Processo para a preparacao de naftotiazepinonas e de composicoes farmaceuticas que as contem
PT81531B (pt) Processo para a preparacao de silibinina isenta de isosilibina e de composicoes farmaceuticas contendo silibinina
PT84478B (pt) Processo para a preparacao de derivados de pirazolo-{3,4-d}-pirimidina e de composicoes farmaceuticas que os contem
PT82585B (pt) Processo para a preparacao de composicoes funcigidas e algicidas contendo derivados de piridazinio
BR8904400A (pt) Processo para a preparacao de uma formulacao pesticida
IT1191639B (it) Composizione farmaceutica contenente fosfocreatina e metodo per preparla
BR8604778A (pt) Desodorizador de ar e processo para produzir um desodorizador de ar
PT82352B (pt) Processo para a preparacao de uma composicao praguicida, nomeadamente insecticida e acaricida contendo esteres de acidos vinilciclopropanocarboxilicos