ES2117390T3 - Sales de un acido graso poliinsaturado y formulaciones farmaceuticas que las contienen. - Google Patents

Sales de un acido graso poliinsaturado y formulaciones farmaceuticas que las contienen.

Info

Publication number
ES2117390T3
ES2117390T3 ES95903298T ES95903298T ES2117390T3 ES 2117390 T3 ES2117390 T3 ES 2117390T3 ES 95903298 T ES95903298 T ES 95903298T ES 95903298 T ES95903298 T ES 95903298T ES 2117390 T3 ES2117390 T3 ES 2117390T3
Authority
ES
Spain
Prior art keywords
salts
fatty acid
pharmaceutical formulations
formulations containing
polyinsaturated fatty
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95903298T
Other languages
English (en)
Inventor
Tiberio Bruzzese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prospa NV
Original Assignee
Prospa NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prospa NV filed Critical Prospa NV
Application granted granted Critical
Publication of ES2117390T3 publication Critical patent/ES2117390T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/16—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

SALES DE ACIDO 4,7,10,13,16,19 - CIS - DOCOSAHEXAENOICO (DHA) CON AMINOACIDOS BASICOS, EN PARTICULAR ARGININA Y LISINA, TIENEN CARACTERISTICAS TERAPEUTICAS Y TECNOLOGICAS FAVORABLES (SOLUBILIDAD EN AGUA) COMPARADAS CON EL ACIDO DE INICIO.
ES95903298T 1993-12-14 1994-11-28 Sales de un acido graso poliinsaturado y formulaciones farmaceuticas que las contienen. Expired - Lifetime ES2117390T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI002612A IT1264987B1 (it) 1993-12-14 1993-12-14 Sali di un acido grasso poliinsaturo e formulazioni farmaceutiche che li contengono

Publications (1)

Publication Number Publication Date
ES2117390T3 true ES2117390T3 (es) 1998-08-01

Family

ID=11367322

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95903298T Expired - Lifetime ES2117390T3 (es) 1993-12-14 1994-11-28 Sales de un acido graso poliinsaturado y formulaciones farmaceuticas que las contienen.

Country Status (8)

Country Link
US (1) US5750572A (es)
EP (1) EP0734373B1 (es)
JP (1) JPH09508619A (es)
AU (1) AU1241295A (es)
DE (1) DE69409969T2 (es)
ES (1) ES2117390T3 (es)
IT (1) IT1264987B1 (es)
WO (1) WO1995016661A1 (es)

Families Citing this family (43)

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Publication number Priority date Publication date Assignee Title
US6107499A (en) * 1988-02-26 2000-08-22 Neuromedica, Inc. Dopamine analog amide
AUPM906594A0 (en) * 1994-10-26 1994-11-17 Peptide Technology Limited Synthetic polyunsaturated fatty acid analogues
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6576636B2 (en) * 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US5955459A (en) * 1997-11-26 1999-09-21 Neuromedica, Inc. Fatty acid-antipsychotic compositions and uses thereof
US6197764B1 (en) 1997-11-26 2001-03-06 Protarga, Inc. Clozapine compositions and uses thereof
FR2781371B1 (fr) * 1998-07-21 2001-04-27 Oreal Composition cosmetique aqueuse transparente a une seule phase
US7235583B1 (en) * 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
AU2002303164A1 (en) 2001-03-23 2002-10-08 Protarga, Inc. Fatty amine drug conjugates
ES2387562T3 (es) * 2001-03-23 2012-09-26 Luitpold Pharmaceuticals, Inc. Conjugados alcohol graso-medicamento
GB0210212D0 (en) * 2002-05-03 2002-06-12 Univ Southampton Effects of dietary N-3 and N-6 pufa intake on atheromatous plaque stability
US8729124B2 (en) 2002-03-05 2014-05-20 Pronova Biopharma Norge As Use of EPA and DHA in secondary prevention
JP2003261456A (ja) * 2002-03-08 2003-09-16 Howaizu:Kk 脳の老化予防剤
US7935365B2 (en) 2003-10-22 2011-05-03 Enzymotec, Ltd. Glycerophospholipids for the improvement of cognitive functions
US20050130937A1 (en) * 2003-10-22 2005-06-16 Enzymotec Ltd. Lipids containing omega-3 and omega-6 fatty acids
US8052992B2 (en) * 2003-10-22 2011-11-08 Enzymotec Ltd. Glycerophospholipids containing omega-3 and omega-6 fatty acids and their use in the treatment and improvement of cognitive functions
HU227588B1 (hu) * 2004-12-03 2011-09-28 Sinnex Mueszaki Fejlesztoe Es Tanacsado Kft Többszörösen telítetlen zsírsavak észtereit tartalmazó vírusellenes és immunstimuláns gyógyászati készítmény
ITMI20072142A1 (it) * 2007-11-08 2009-05-09 Yervant Zarmanian Composizioni farmaceutiche contenenti statine e derivati di acidi grassi omega-3
CN105267969A (zh) * 2008-01-04 2016-01-27 雀巢产品技术援助有限公司 包含不饱和脂肪酸和一氧化氮释放化合物的组合物及其用于增强认知和相关功能的用途
CN102316865B (zh) 2008-12-12 2017-04-19 科耐特有限公司 用于改善正常的认知功能的l‑赖氨酸
UA114615C2 (uk) 2012-01-06 2017-07-10 Омтера Фармасьютікалз, Інк. Збагачена дпк композиція омега-3 поліненасичених жирних кислот у формі вільної кислоти
US9999626B2 (en) * 2014-06-18 2018-06-19 Thetis Pharmaceuticals Llc Mineral amino-acid complexes of active agents
RU2706072C2 (ru) * 2014-12-23 2019-11-13 Эвоник Дегусса Гмбх Способ повышения устойчивости композиции, содержащей омега-6 полиненасыщенные жирные кислоты
SG11201704396XA (en) * 2014-12-23 2017-07-28 Evonik Degussa Gmbh Process for increasing the stability of a composition comprising polyunsaturated omega-3 fatty acids
FR3031451B1 (fr) * 2015-01-13 2018-03-23 Greentech Sel d'un triglyceride, preparation et utilisations
AU2017270134B2 (en) * 2016-05-25 2022-09-01 Evonik Operations Gmbh Tablets with high active ingredient content of omega-3 fatty acid amino acid salts
EP3248467A1 (de) * 2016-05-25 2017-11-29 Evonik Technochemie GmbH Verfahren zur herstellung einer zusammensetzung enthaltend omega-3-fettsäure-l-lysin-salze
EP3454907B1 (en) 2016-06-03 2020-07-22 Thetis Pharmaceuticals LLC Compositions and methods relating to salts of specialized pro-resolving mediators of inflammation
WO2019008101A1 (en) 2017-07-06 2019-01-10 Evonik Technochemie Gmbh ENTERICALLY COATED SOLID DOSAGE FORM COMPRISING AMINO ACIDS SALTS OF OMEGA-3 FATTY ACIDS
WO2019034698A1 (en) 2017-08-15 2019-02-21 Evonik Technochemie Gmbh TABLET WITH HIGH ACTIVE INGREDIENT CONTENT OF OMEGA-3 FATTY ACID AMINO ACID SALTS
WO2019093708A1 (ko) * 2017-11-08 2019-05-16 김승수 악취 억제형 불포화오일 및 아르기닌 함유 조성물의 제조 방법
KR102172036B1 (ko) * 2017-11-08 2020-10-30 주식회사 오스테온 악취 억제형 불포화오일 및 아르기닌 함유 조성물의 제조 방법
CA3121055C (en) * 2018-11-30 2024-04-16 Evonik Operations Gmbh Preparation comprising a dispersion of phospholipids and fatty acid salts
WO2020225068A1 (en) 2019-05-06 2020-11-12 Evonik Operations Gmbh Preparation for use in weight management comprising omega-3 fatty acid salts and basic amino acids
US20220287345A1 (en) 2019-08-08 2022-09-15 Evonik Operations Gmbh Solubility enhancement of poorly soluble actives
US20220280388A1 (en) 2019-08-08 2022-09-08 Evonik Operations Gmbh Method of preparing a solid dosage form and a binder
JP2022543283A (ja) 2019-08-08 2022-10-11 エボニック オペレーションズ ゲーエムベーハー 多価不飽和脂肪酸塩を製造するための下流処理
EP3804699A1 (en) 2019-10-10 2021-04-14 Evonik Operations GmbH Method of preparing a solid dosage form and a binder
MX2022001568A (es) 2019-08-08 2022-03-02 Evonik Operations Gmbh Procedimiento de preparacion de una forma de dosificacion solida y un lubricante.
AU2021213077A1 (en) * 2020-01-30 2022-09-08 Silicycle Inc. Process for preparing a solid form of basic amino acid salts of polyunsaturated fatty acids
US20230037453A1 (en) 2020-04-01 2023-02-09 Evonik Operations Gmbh Preparation for use as vasorelaxant
US20230149336A1 (en) 2020-04-01 2023-05-18 Evonik Operations Gmbh Preparation for use as antioxidant
DE102022003441A1 (de) 2022-09-17 2024-03-28 Jutta Ibrahim Nahrungsergänzungsmittel Omega3 und essentielle Aminosäure(n)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7405325A (es) * 1973-04-25 1974-10-29
HU209973B (en) * 1988-03-09 1995-01-30 Biorex Kutato Fejlesztoe Kft Process for production of antiviral and immunstimular pharmaceutical composition
GB8819110D0 (en) * 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production

Also Published As

Publication number Publication date
WO1995016661A1 (en) 1995-06-22
ITMI932612A0 (it) 1993-12-14
IT1264987B1 (it) 1996-10-17
US5750572A (en) 1998-05-12
EP0734373B1 (en) 1998-04-29
ITMI932612A1 (it) 1995-06-14
JPH09508619A (ja) 1997-09-02
AU1241295A (en) 1995-07-03
EP0734373A1 (en) 1996-10-02
DE69409969T2 (de) 1998-12-10
DE69409969D1 (de) 1998-06-04

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