DE69409969D1 - Salze der mehrfach ungesättigten fettsäuren und diese enthaltende pharmazeutischen zusammensetzungen - Google Patents

Salze der mehrfach ungesättigten fettsäuren und diese enthaltende pharmazeutischen zusammensetzungen

Info

Publication number
DE69409969D1
DE69409969D1 DE69409969T DE69409969T DE69409969D1 DE 69409969 D1 DE69409969 D1 DE 69409969D1 DE 69409969 T DE69409969 T DE 69409969T DE 69409969 T DE69409969 T DE 69409969T DE 69409969 D1 DE69409969 D1 DE 69409969D1
Authority
DE
Germany
Prior art keywords
fatty acid
pharmaceutical compositions
compositions containing
unsaturated fatty
acid salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69409969T
Other languages
English (en)
Other versions
DE69409969T2 (de
Inventor
Tiberio Bruzzese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prospa NV
Original Assignee
Prospa NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prospa NV filed Critical Prospa NV
Application granted granted Critical
Publication of DE69409969D1 publication Critical patent/DE69409969D1/de
Publication of DE69409969T2 publication Critical patent/DE69409969T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/16—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DE69409969T 1993-12-14 1994-11-28 Salze der mehrfach ungesättigten fettsäuren und diese enthaltende pharmazeutischen zusammensetzungen Expired - Lifetime DE69409969T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT93MI002612A IT1264987B1 (it) 1993-12-14 1993-12-14 Sali di un acido grasso poliinsaturo e formulazioni farmaceutiche che li contengono
PCT/EP1994/003943 WO1995016661A1 (en) 1993-12-14 1994-11-28 Salts of a polyunsaturated fatty acid and pharmaceutical formulations containing them

Publications (2)

Publication Number Publication Date
DE69409969D1 true DE69409969D1 (de) 1998-06-04
DE69409969T2 DE69409969T2 (de) 1998-12-10

Family

ID=11367322

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69409969T Expired - Lifetime DE69409969T2 (de) 1993-12-14 1994-11-28 Salze der mehrfach ungesättigten fettsäuren und diese enthaltende pharmazeutischen zusammensetzungen

Country Status (8)

Country Link
US (1) US5750572A (de)
EP (1) EP0734373B1 (de)
JP (1) JPH09508619A (de)
AU (1) AU1241295A (de)
DE (1) DE69409969T2 (de)
ES (1) ES2117390T3 (de)
IT (1) IT1264987B1 (de)
WO (1) WO1995016661A1 (de)

Families Citing this family (44)

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US6107499A (en) * 1988-02-26 2000-08-22 Neuromedica, Inc. Dopamine analog amide
AUPM906594A0 (en) * 1994-10-26 1994-11-17 Peptide Technology Limited Synthetic polyunsaturated fatty acid analogues
US5795909A (en) 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6576636B2 (en) 1996-05-22 2003-06-10 Protarga, Inc. Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US5955459A (en) * 1997-11-26 1999-09-21 Neuromedica, Inc. Fatty acid-antipsychotic compositions and uses thereof
US6197764B1 (en) 1997-11-26 2001-03-06 Protarga, Inc. Clozapine compositions and uses thereof
FR2781371B1 (fr) * 1998-07-21 2001-04-27 Oreal Composition cosmetique aqueuse transparente a une seule phase
US7235583B1 (en) * 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
US8552054B2 (en) 2001-03-23 2013-10-08 Luitpold Pharmaceuticals, Inc. Fatty amine drug conjugates
EP1423107B1 (de) * 2001-03-23 2012-05-09 Luitpold Pharmaceuticals, Inc. Fettalkohol-arzneimittel-konjugate
US8729124B2 (en) 2002-03-05 2014-05-20 Pronova Biopharma Norge As Use of EPA and DHA in secondary prevention
GB0210212D0 (en) * 2002-05-03 2002-06-12 Univ Southampton Effects of dietary N-3 and N-6 pufa intake on atheromatous plaque stability
JP2003261456A (ja) * 2002-03-08 2003-09-16 Howaizu:Kk 脳の老化予防剤
US20050130937A1 (en) * 2003-10-22 2005-06-16 Enzymotec Ltd. Lipids containing omega-3 and omega-6 fatty acids
US7935365B2 (en) 2003-10-22 2011-05-03 Enzymotec, Ltd. Glycerophospholipids for the improvement of cognitive functions
US8052992B2 (en) * 2003-10-22 2011-11-08 Enzymotec Ltd. Glycerophospholipids containing omega-3 and omega-6 fatty acids and their use in the treatment and improvement of cognitive functions
HU227588B1 (hu) * 2004-12-03 2011-09-28 Sinnex Mueszaki Fejlesztoe Es Tanacsado Kft Többszörösen telítetlen zsírsavak észtereit tartalmazó vírusellenes és immunstimuláns gyógyászati készítmény
ITMI20072142A1 (it) * 2007-11-08 2009-05-09 Yervant Zarmanian Composizioni farmaceutiche contenenti statine e derivati di acidi grassi omega-3
ES2773928T5 (es) 2008-01-04 2023-06-28 Nestle Sa Composiciones que comprenden ácidos grasos insaturados y compuestos de liberación de óxido nítrico y uso de las mismas para la intensificación de las funciones cognitivas y relacionadas
WO2010068173A1 (en) 2008-12-12 2010-06-17 Daniel Klamer L-lysine for improving normal cognitive functions
KR102153143B1 (ko) 2012-01-06 2020-09-08 옴테라 파마슈티칼스, 인크. 유리 산 형태의 오메가-3 다중불포화 지방산의 ｄｐａ-농축 조성물
WO2015195491A1 (en) * 2014-06-18 2015-12-23 Thetis Pharmaceuticals Llc Mineral amino-acid complexes of active agents
MX2017008274A (es) * 2014-12-23 2017-10-02 Evonik Degussa Gmbh Proceso para aumentar la estabilidad de una composicion que comprende acidos grasos omega-6 poliinsaturados.
KR102584130B1 (ko) 2014-12-23 2023-10-04 에보니크 오퍼레이션즈 게엠베하 다중불포화 오메가-3 지방산을 포함하는 조성물의 안정성을 증가시키는 방법
FR3031451B1 (fr) * 2015-01-13 2018-03-23 Greentech Sel d'un triglyceride, preparation et utilisations
EP3248467A1 (de) 2016-05-25 2017-11-29 Evonik Technochemie GmbH Verfahren zur herstellung einer zusammensetzung enthaltend omega-3-fettsäure-l-lysin-salze
EP3463310B1 (de) * 2016-05-25 2023-07-05 Evonik Operations GmbH Tabletten mit hohem wirkstoffgehalt von omega-3-fettsäure-aminosäuresalzen
EP3454907B1 (de) 2016-06-03 2020-07-22 Thetis Pharmaceuticals LLC Zusammensetzungen und verfahren in zusammenhang mit salzen von specialised pro-resolving mediatoren von entzündung
WO2019008101A1 (en) 2017-07-06 2019-01-10 Evonik Technochemie Gmbh ENTERICALLY COATED SOLID DOSAGE FORM COMPRISING AMINO ACIDS SALTS OF OMEGA-3 FATTY ACIDS
KR102628351B1 (ko) * 2017-08-15 2024-01-25 에보니크 오퍼레이션즈 게엠베하 오메가-3 지방산 아미노산 염의 높은 활성 성분 함량을 갖는 정제
KR102172036B1 (ko) * 2017-11-08 2020-10-30 주식회사 오스테온 악취 억제형 불포화오일 및 아르기닌 함유 조성물의 제조 방법
WO2019093708A1 (ko) * 2017-11-08 2019-05-16 김승수 악취 억제형 불포화오일 및 아르기닌 함유 조성물의 제조 방법
JP7438216B2 (ja) * 2018-11-30 2024-02-26 エボニック オペレーションズ ゲーエムベーハー リン脂質と脂肪酸塩の分散体を含む調製物
EP3965755A1 (de) 2019-05-06 2022-03-16 Evonik Operations GmbH Präparat zur verwendung in der gewichtskontrolle mit omega-3-fettsäuresalzen und basischen aminosäuren
WO2020234221A1 (en) * 2019-05-23 2020-11-26 Evonik Operations Gmbh Prebiotic compositions
EP4009960A1 (de) 2019-08-08 2022-06-15 Evonik Operations GmbH Verfahren zur herstellung einer festen darreichungsform und eines bindemittels
MX2022001570A (es) 2019-08-08 2022-03-02 Evonik Operations Gmbh Proceso de flujo descendente para la produccion de sales de acidos grasos poliinsaturados.
EP3804699A1 (de) 2019-10-10 2021-04-14 Evonik Operations GmbH Verfahren zur herstellung einer festen darreichungsform und eines bindemittels
US20220287979A1 (en) 2019-08-08 2022-09-15 Evonik Operations Gmbh Method of preparing a solid dosage form and a lubricant
US20220287345A1 (en) 2019-08-08 2022-09-15 Evonik Operations Gmbh Solubility enhancement of poorly soluble actives
WO2021151199A1 (en) * 2020-01-30 2021-08-05 Silicycle Inc. Process for preparing a solid form of basic amino acid salts of polyunsaturated fatty acids
WO2021197969A1 (en) 2020-04-01 2021-10-07 Evonik Operations Gmbh Preparation for use as vasorelaxant
WO2021197971A1 (en) 2020-04-01 2021-10-07 Evonik Operations Gmbh Preparation for use as antioxidant
DE102022003441A1 (de) 2022-09-17 2024-03-28 Jutta Ibrahim Nahrungsergänzungsmittel Omega3 und essentielle Aminosäure(n)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7405325A (de) * 1973-04-25 1974-10-29
HU209973B (en) * 1988-03-09 1995-01-30 Biorex Kutato Fejlesztoe Kft Process for production of antiviral and immunstimular pharmaceutical composition
GB8819110D0 (en) * 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production

Also Published As

Publication number Publication date
EP0734373A1 (de) 1996-10-02
ITMI932612A0 (it) 1993-12-14
WO1995016661A1 (en) 1995-06-22
IT1264987B1 (it) 1996-10-17
DE69409969T2 (de) 1998-12-10
ITMI932612A1 (it) 1995-06-14
ES2117390T3 (es) 1998-08-01
US5750572A (en) 1998-05-12
EP0734373B1 (de) 1998-04-29
JPH09508619A (ja) 1997-09-02
AU1241295A (en) 1995-07-03

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Legal Events

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