IL107758A - 4-substituted catechol diethers as selective phosphodiesterase iv inhibitors - Google Patents

4-substituted catechol diethers as selective phosphodiesterase iv inhibitors

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Publication number
IL107758A
IL107758A IL107758A IL10775893A IL107758A IL 107758 A IL107758 A IL 107758A IL 107758 A IL107758 A IL 107758A IL 10775893 A IL10775893 A IL 10775893A IL 107758 A IL107758 A IL 107758A
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IL
Israel
Prior art keywords
inhibitors
substituted catechol
compounds
selective phosphodiesterase
relates
Prior art date
Application number
IL107758A
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English (en)
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IL107758A0 (en
Original Assignee
Pfizer
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Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL107758A0 publication Critical patent/IL107758A0/xx
Publication of IL107758A publication Critical patent/IL107758A/xx

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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
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    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
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    • C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
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    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/18—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
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    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
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IL107758A 1992-12-02 1993-11-25 4-substituted catechol diethers as selective phosphodiesterase iv inhibitors IL107758A (en)

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PL309257A1 (en) 1995-10-02
ATE234270T1 (de) 2003-03-15
NZ257955A (en) 1996-05-28
RU95113454A (ru) 1997-06-10
FI935379A0 (fi) 1993-12-01
HUT65928A (en) 1994-07-28
NO952178D0 (no) 1995-06-01
EP0672031A1 (en) 1995-09-20
AU5539694A (en) 1994-06-22
BR9307570A (pt) 1999-05-25
ES2192192T3 (es) 2003-10-01
CA2150812C (en) 2002-12-24
JP3100984B2 (ja) 2000-10-23
IL107758A0 (en) 1994-02-27
CA2400368A1 (en) 1994-06-09
FI935379A (fi) 1994-06-03
WO1994012461A1 (en) 1994-06-09
ZA938978B (en) 1995-06-01
HU9303423D0 (en) 1994-04-28
DK0672031T3 (da) 2003-06-10
JPH08501318A (ja) 1996-02-13
DE69332762T2 (de) 2003-08-14
AU673569B2 (en) 1996-11-14
CZ141795A3 (en) 1995-11-15
NO952178L (no) 1995-08-01
KR950704228A (ko) 1995-11-17
DE69332762D1 (de) 2003-04-17
CN1094028A (zh) 1994-10-26
EP0672031B1 (en) 2003-03-12
CA2150812A1 (en) 1994-06-09
PT672031E (pt) 2003-06-30

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