ES2192192T3 - Dieteres de catecol como inhibidores selectivos de pde iv. - Google Patents

Dieteres de catecol como inhibidores selectivos de pde iv.

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Publication number
ES2192192T3
ES2192192T3 ES94900390T ES94900390T ES2192192T3 ES 2192192 T3 ES2192192 T3 ES 2192192T3 ES 94900390 T ES94900390 T ES 94900390T ES 94900390 T ES94900390 T ES 94900390T ES 2192192 T3 ES2192192 T3 ES 2192192T3
Authority
ES
Spain
Prior art keywords
catecol
compounds
diets
pde inhibitors
selective pde
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94900390T
Other languages
English (en)
Inventor
Allen J Duplantier
James F Eggler
Anthony Marfat
Hiroko Masamune
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
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Filing date
Publication date
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Publication of ES2192192T3 publication Critical patent/ES2192192T3/es
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    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
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Abstract

ESTA INVENCION SE REFIERE A COMPUESTOS DE DIETER DE CATECOL DE 4-SUSTITUIDO QUE SON INHIBIDORES SELECTIVOS DE FOSFODIESTERASA (PDE) TIPO IV. LOS COMPUESTOS DE LA PRESENTE INVENCION SON UTILES EN LA INHIBICION DE PDEIV Y EN EL TRATAMIENTO DEL SIDA, ASMA, ARTRITIS, BRONQUITIS, ENFERMEDAD DE LAS VIAS RESPIRATORIAS CRONICAS, PSORIASIS, RINITIS ALERGICA, DERMATITIS Y OTRAS ENFERMEDADES INFLAMATORIAS. ESTA INVENCION TAMBIEN SE REFIERE A LAS COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN ESTOS COMPUESTOS.
ES94900390T 1992-12-02 1993-10-29 Dieteres de catecol como inhibidores selectivos de pde iv. Expired - Lifetime ES2192192T3 (es)

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IL107758A0 (en) 1994-02-27
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