AU4298997A - Thiazole derivatives useful as selective inhibitors of pde-iv - Google Patents

Thiazole derivatives useful as selective inhibitors of pde-iv

Info

Publication number
AU4298997A
AU4298997A AU42989/97A AU4298997A AU4298997A AU 4298997 A AU4298997 A AU 4298997A AU 42989/97 A AU42989/97 A AU 42989/97A AU 4298997 A AU4298997 A AU 4298997A AU 4298997 A AU4298997 A AU 4298997A
Authority
AU
Australia
Prior art keywords
pde
selective inhibitors
derivatives useful
thiazole derivatives
thiazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU42989/97A
Inventor
Hermann Amschler
Thomas Bar
Rolf Beume
Hildegard Boss
Dieter Flockerzi
Beate Gutterer
Dietrich Hafner
Armin Hatzelmann
Hans-Peter Kley
Thomas Martin
Ulrich Thibaut
Wolf-Rudiger Ulrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Publication of AU4298997A publication Critical patent/AU4298997A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU42989/97A 1996-08-26 1997-08-13 Thiazole derivatives useful as selective inhibitors of pde-iv Abandoned AU4298997A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19634409 1996-08-26
DE19634409 1996-08-26
EP96113738 1996-08-28
EP96113738 1996-08-28
PCT/EP1997/004397 WO1998008844A1 (en) 1996-08-26 1997-08-13 Thiazole derivatives useful as selective inhibitors of pde-iv

Publications (1)

Publication Number Publication Date
AU4298997A true AU4298997A (en) 1998-03-19

Family

ID=26028745

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42989/97A Abandoned AU4298997A (en) 1996-08-26 1997-08-13 Thiazole derivatives useful as selective inhibitors of pde-iv

Country Status (2)

Country Link
AU (1) AU4298997A (en)
WO (1) WO1998008844A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK287231B6 (en) 1999-08-21 2010-04-07 Nycomed Gmbh Medicament comprising a PDE inhibitor and a beta2 adrenoreceptor agonist
DE60139639D1 (en) * 2000-12-08 2009-10-01 Takeda Pharmaceutical SUBSTITUTED THIAZONE DERIVATIVES WITH 3-PYRIDYL GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR USE
EP1348701A1 (en) * 2002-03-28 2003-10-01 Warner-Lambert Company LLC (2,4-disubstituted-thiazol-5-yl) amine compounds as PDE7 inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1248070A (en) * 1968-12-16 1971-09-29 Science Union & Cie Thiazolyl-benzoic acid derivatives and process for preparing them
US4528291A (en) * 1982-06-22 1985-07-09 Schering Corporation 2-(4'-Pyridinyl)-thiazole compounds and their use in increasing cardiac contractility
GB8917849D0 (en) * 1989-08-04 1989-09-20 Shell Int Research Thiazole derivatives,their preparation and their use as fungicides
CA2074933C (en) * 1990-11-30 2002-12-03 Masatoshi Chihiro Thiazole derivatives as active superoxide radical inhibitors
WO1993024472A1 (en) * 1992-05-29 1993-12-09 Otsuka Pharmaceutical Co., Ltd. Thiazole derivative
CA2400368A1 (en) * 1992-12-02 1994-06-09 Allen J. Duplantier Catechol diethers as selective pde iv inhibitors
JPH07215952A (en) * 1993-12-06 1995-08-15 Otsuka Pharmaceut Factory Inc Catechol derivative

Also Published As

Publication number Publication date
WO1998008844A1 (en) 1998-03-05

Similar Documents

Publication Publication Date Title
AU4791797A (en) 6-phenylpyridyl-2-amine derivatives useful as nos inhibitors
AU6178894A (en) Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
AU3343097A (en) Phenylalamine derivatives as integrin inhibitors
AU6718494A (en) 2-substituted-3,4-diarylthiophene derivatives as inhibitors of cyclooxygenase
AU8875798A (en) Meta-benzamidine derivatives as serin protease inhibitors
PL329639A1 (en) Urea derivatives as inhibitors of impdh enzyme
AU4015497A (en) Thiazole derivatives useful as selective inhibitors of pde-iv
AU3379097A (en) Aromatic heterocyclic derivatives as enzyme inhibitors
AU3039995A (en) Heterocyclic derivatives of N-phenylamides
PL329153A1 (en) Derivatives of pyrrolopyrolone as inhibitors of neutropil elastase
AU1605699A (en) Substituted 3-amino-2-hydroxyphenylacetamide derivatives as enzyme inhibitors (ii)
AU3827897A (en) 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase
PL333925A1 (en) Method of obtaining derivatives of thiazole
AU3075595A (en) Anti-helicobacter heterocyclic derivatives of azolones
AU2277597A (en) New inhibitors of sh2-mediated processes
AU1766997A (en) Beta-thiopropionyl-aminoacid derivatives and their use as beta-lactamase inhibitors
AU1817700A (en) 1-carboxymethyl-2-oxo-azepan derivatives useful as selective inhibitors of mmp-12
AU6292998A (en) Process for the preparation of thiazole derivatives
AU5737498A (en) Method for the preparation of alpha-bromo-lactam derivatives
AU4298997A (en) Thiazole derivatives useful as selective inhibitors of pde-iv
AU2408995A (en) Short chain 2-hydroxycarboxylic acid-based derivatives of ceramides
AU2595297A (en) Use of aminoalkylcarboxylic derivatives
AU2063397A (en) Mercapto derivatives as inhibitors of cyclooxygenases
AU3708997A (en) P-toluenesulfonate hydrate of thiazoline compound
AU2230897A (en) Thiazolidine derivatives