IL102946A0 - Pyrazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

Pyrazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
IL102946A0
IL102946A0 IL102946A IL10294692A IL102946A0 IL 102946 A0 IL102946 A0 IL 102946A0 IL 102946 A IL102946 A IL 102946A IL 10294692 A IL10294692 A IL 10294692A IL 102946 A0 IL102946 A0 IL 102946A0
Authority
IL
Israel
Prior art keywords
processes
preparation
same
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL102946A
Other languages
English (en)
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919119267A external-priority patent/GB9119267D0/en
Priority claimed from GB929204464A external-priority patent/GB9204464D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of IL102946A0 publication Critical patent/IL102946A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL102946A 1991-09-09 1992-08-25 Pyrazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same IL102946A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919119267A GB9119267D0 (en) 1991-09-09 1991-09-09 Pyrazole derivatives
GB929204464A GB9204464D0 (en) 1992-03-02 1992-03-02 New heterocyclic derivatives

Publications (1)

Publication Number Publication Date
IL102946A0 true IL102946A0 (en) 1993-01-31

Family

ID=26299519

Family Applications (1)

Application Number Title Priority Date Filing Date
IL102946A IL102946A0 (en) 1991-09-09 1992-08-25 Pyrazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same

Country Status (10)

Country Link
US (3) US5356897A (index.php)
EP (1) EP0531901A3 (index.php)
JP (2) JPH0788386B2 (index.php)
CN (1) CN1070404A (index.php)
AU (1) AU2280592A (index.php)
CA (1) CA2077732A1 (index.php)
HU (1) HUT65204A (index.php)
IL (1) IL102946A0 (index.php)
MX (1) MX9205145A (index.php)
TW (1) TW257763B (index.php)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
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US6277969B1 (en) * 1991-03-18 2001-08-21 New York University Anti-TNF antibodies and peptides of human tumor necrosis factor
US5356897A (en) * 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines
GB9303993D0 (en) * 1993-02-26 1993-04-14 Fujisawa Pharmaceutical Co New heterocyclic derivatives
EP0621036B1 (en) * 1993-04-22 1999-03-17 Senju Pharmaceutical Co., Ltd. Aqueous compositions comprising argatroban and cyclodextrin or caffeine
CA2166721C (en) * 1993-07-06 1999-07-27 Allen Jacob Duplantier Bicyclic tetrahydro pyrazolopyridines
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
US6228871B1 (en) 1995-07-10 2001-05-08 Merck & Co., Inc. Angiogenesis inhibitors
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WO1998002430A1 (en) 1996-07-11 1998-01-22 Pfizer Pharmaceuticals Inc. Pyridylpyrrole compounds useful as interleukin- and tnf antagonists
US6060478A (en) * 1996-07-24 2000-05-09 Dupont Pharmaceuticals Azolo triazines and pyrimidines
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US7094782B1 (en) 1996-07-24 2006-08-22 Bristol-Myers Squibb Company Azolo triazines and pyrimidines
US6313124B1 (en) 1997-07-23 2001-11-06 Dupont Pharmaceuticals Company Tetrazine bicyclic compounds
US6191131B1 (en) 1997-07-23 2001-02-20 Dupont Pharmaceuticals Company Azolo triazines and pyrimidines
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US6124289A (en) * 1996-07-24 2000-09-26 Dupont Pharmaceuticals Co. Azolo triazines and pyrimidines
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US6087496A (en) 1998-05-22 2000-07-11 G. D. Searle & Co. Substituted pyrazoles suitable as p38 kinase inhibitors
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US6979686B1 (en) 2001-12-07 2005-12-27 Pharmacia Corporation Substituted pyrazoles as p38 kinase inhibitors
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US6380203B1 (en) * 1998-01-14 2002-04-30 Merck & Co., Inc. Angiogenesis inhibitors
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NZ512534A (en) 1998-12-23 2003-11-28 G Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications
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DK1140190T3 (da) 1998-12-23 2002-12-23 Searle Llc Kombinationer af ileumgaldesyretransport-inhibitorer og galdesyre-sekvestreringsmidler til cardiovaskulære indikatorer
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WO2000059907A2 (en) 1999-04-06 2000-10-12 Du Pont Pharmaceuticals Company Pyrazolotriazines as crf antagonists
AU2006203676B2 (en) * 1999-08-13 2010-04-22 Vertex Pharmaceuticals Incorporated Inhibitors of c-JUN N-Terminal Kinases (JNK) and Other Protein Kinases
AR032130A1 (es) 1999-08-13 2003-10-29 Vertex Pharma Un compuesto inhibidor de quinasas proteicas, una composicion farmaceutica que lo incluye, y un metodo para tratar afecciones con dicho compuesto
US6472416B1 (en) 1999-08-27 2002-10-29 Abbott Laboratories Sulfonylphenylpyrazole compounds useful as COX-2 inhibitors
ATE267830T1 (de) * 1999-08-27 2004-06-15 Abbott Lab Als cox-hemmer verwendbare sulfonylphenylpyrazol- verbindungen
EP1208748A4 (en) * 1999-08-31 2002-11-20 Fujisawa Pharmaceutical Co PRESERVATIVES FOR ORGANS
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US6630476B2 (en) 2000-07-07 2003-10-07 Bristol-Myers Squibb Pharma Company Pyrrolo [3,4-d] pyrimidines as corticotropin releasing factor (CRF) antagonists
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DK1397364T3 (da) * 2001-05-24 2007-11-26 Lilly Co Eli Hidtil ukendte pyrrolderivater som farmaceutiske midler
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US6852753B2 (en) 2002-01-17 2005-02-08 Pharmacia Corporation Alkyl/aryl hydroxy or keto thiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake
JP2005529919A (ja) * 2002-05-10 2005-10-06 スミスクライン ビーチャム コーポレーション 治療用化合物
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DE10332487A1 (de) * 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung von chronisch nozizeptiven Schmerzen
US7511065B2 (en) 2003-11-12 2009-03-31 Eli Lilly And Company Mixed lineage kinase modulators
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
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KR20080049758A (ko) * 2005-09-01 2008-06-04 아스텔라스세이야쿠 가부시키가이샤 통증 치료용으로 사용되는 피리다지논 유도체
WO2007129195A2 (en) * 2006-05-04 2007-11-15 Pfizer Products Inc. 4-pyrimidine-5-amino-pyrazole compounds
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CN101889012A (zh) * 2007-12-12 2010-11-17 杜邦公司 杀真菌二环吡唑
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RU2543386C2 (ru) 2010-02-26 2015-02-27 Мицубиси Танабе Фарма Коропорейшн Производные пиразолопиримидина и их применение в качестве ингибиторов pde10
WO2011133520A1 (en) 2010-04-19 2011-10-27 Synta Pharmaceuticals Corp. Cancer therapy using a combination of a hsp90 inhibitory compounds and a egfr inhibitor
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CN105188694B (zh) 2013-03-15 2018-07-31 卓莫赛尔公司 用于治疗疼痛的钠通道调节剂
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CN105611923B (zh) 2013-09-10 2019-08-23 卓莫赛尔公司 用于治疗疼痛和糖尿病的钠通道调节剂
EA031639B1 (ru) * 2014-03-27 2019-01-31 Янссен Фармацевтика Нв ЗАМЕЩЕННЫЕ 4,5,6,7-ТЕТРАГИДРОПИРАЗОЛО[1,5-а]ПИРИМИДИНОВЫЕ ПРОИЗВОДНЫЕ И 2,3-ДИГИДРО-1H-ИМИДАЗО[1,2-b]ПИРАЗОЛЬНЫЕ ПРОИЗВОДНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ ROS1
JP6522646B2 (ja) 2014-03-27 2019-05-29 ヤンセン ファーマシューティカ エヌ．ベー． ＲＯＳ１阻害剤としての置換４，５，６，７−テトラヒドロ−ピラゾロ［１，５−α］ピラジン誘導体および５，６，７，８−テトラヒドロ−４Ｈ−ピラゾロ［１，５−α］［１，４］ジアゼピン誘導体
CN104140427A (zh) * 2014-07-05 2014-11-12 湖南华腾制药有限公司 一种四氢吡唑并[1,5-a]嘧啶的制备方法
JP2017527573A (ja) * 2014-09-09 2017-09-21 クロモセル コーポレーション 糖尿病の治療用の選択的ＮａＶ１．７阻害剤
KR102384652B1 (ko) * 2015-02-03 2022-04-27 솔루스첨단소재 주식회사 유기 화합물 및 이를 포함하는 유기 전계 발광 소자
CA3034705C (en) 2016-08-31 2021-08-03 Agios Pharmaceuticals, Inc. Inhibitors of cellular metabolic processes
US12479816B2 (en) 2019-02-08 2025-11-25 University of Pittsburgh—of the Commonwealth System of Higher Education 20-HETE formation inhibitors
BR112022010924A2 (pt) 2019-12-06 2022-09-06 Vertex Pharma Tetra-hidrofuranos substituídos como moduladores de canais de sódio
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CA3188730A1 (en) 2020-08-12 2022-02-17 Christopher Barnes Methods and compositions for treating polycystic ovary syndrome
KR20240031300A (ko) 2021-06-04 2024-03-07 버텍스 파마슈티칼스 인코포레이티드 나트륨 채널 조절제로서의 n-(하이드록시알킬 (헤테로)아릴) 테트라하이드로푸란 카르복스아미드
TW202404969A (zh) 2022-04-22 2024-02-01 美商維泰克斯製藥公司 用於治療疼痛之雜芳基化合物

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US5356897A (en) * 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines

Also Published As

Publication number Publication date
HU9202877D0 (en) 1992-11-30
EP0531901A3 (en) 1993-05-05
US5478827A (en) 1995-12-26
JPH07252256A (ja) 1995-10-03
JPH0788386B2 (ja) 1995-09-27
TW257763B (index.php) 1995-09-21
US5356897A (en) 1994-10-18
JPH06287188A (ja) 1994-10-11
EP0531901A2 (en) 1993-03-17
HUT65204A (en) 1994-05-02
MX9205145A (es) 1993-04-01
CA2077732A1 (en) 1993-03-10
US5624931A (en) 1997-04-29
CN1070404A (zh) 1993-03-31
AU2280592A (en) 1993-03-11

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Legal Events

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HC Change of name of proprietor(s)