IL101394A - תרכובות חדשים, המכונות " ליוסטרודוצינים" , הכנתן ושימושן התרופתי - Google Patents
תרכובות חדשים, המכונות " ליוסטרודוצינים" , הכנתן ושימושן התרופתיInfo
- Publication number
- IL101394A IL101394A IL10139492A IL10139492A IL101394A IL 101394 A IL101394 A IL 101394A IL 10139492 A IL10139492 A IL 10139492A IL 10139492 A IL10139492 A IL 10139492A IL 101394 A IL101394 A IL 101394A
- Authority
- IL
- Israel
- Prior art keywords
- doublet
- leustroducsins
- cells
- triplet
- culture
- Prior art date
Links
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- 229920002223 polystyrene Polymers 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000002953 preparative HPLC Methods 0.000 description 1
- 238000004262 preparative liquid chromatography Methods 0.000 description 1
- 208000019585 progressive encephalomyelitis with rigidity and myoclonus Diseases 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
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- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
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- 229920006395 saturated elastomer Polymers 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 239000004317 sodium nitrate Substances 0.000 description 1
- 235000010344 sodium nitrate Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000000707 stereoselective effect Effects 0.000 description 1
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- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
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- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- FKHIFSZMMVMEQY-UHFFFAOYSA-N talc Chemical compound [Mg+2].[O-][Si]([O-])=O FKHIFSZMMVMEQY-UHFFFAOYSA-N 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- ITMCEJHCFYSIIV-UHFFFAOYSA-N triflic acid Chemical compound OS(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-N 0.000 description 1
- 229910052722 tritium Inorganic materials 0.000 description 1
- 102000003390 tumor necrosis factor Human genes 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 235000015099 wheat brans Nutrition 0.000 description 1
- 229940075420 xanthine Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/903—Streptomyces platensis
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6308791 | 1991-03-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL101394A0 IL101394A0 (en) | 1992-11-15 |
| IL101394A true IL101394A (he) | 1996-05-14 |
Family
ID=13219198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10139492A IL101394A (he) | 1991-03-27 | 1992-03-27 | תרכובות חדשים, המכונות " ליוסטרודוצינים" , הכנתן ושימושן התרופתי |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US5334587A (he) |
| EP (1) | EP0506463B1 (he) |
| JP (1) | JPH05123179A (he) |
| KR (1) | KR0145680B1 (he) |
| CN (1) | CN1058294C (he) |
| AT (1) | ATE134640T1 (he) |
| AU (1) | AU649116B2 (he) |
| CA (1) | CA2064126A1 (he) |
| CZ (1) | CZ279299B6 (he) |
| DE (1) | DE69208494T2 (he) |
| DK (1) | DK0506463T3 (he) |
| ES (1) | ES2086651T3 (he) |
| FI (1) | FI101978B (he) |
| GR (1) | GR3019996T3 (he) |
| HK (1) | HK117696A (he) |
| HU (1) | HU216875B (he) |
| IE (1) | IE74389B1 (he) |
| IL (1) | IL101394A (he) |
| IS (1) | IS1604B (he) |
| NO (1) | NO304600B1 (he) |
| NZ (1) | NZ242155A (he) |
| RU (1) | RU2082760C1 (he) |
| TW (1) | TW212182B (he) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU649116B2 (en) * | 1991-03-27 | 1994-05-12 | Sankyo Company Limited | New compounds, named the "Leustroducins", their preparation and their therapeutic uses |
| ATE166058T1 (de) * | 1993-04-23 | 1998-05-15 | Sankyo Co | Neue verbindung, leustroducsin h, ihre herstellung und therapeutische verwendung |
| WO1997014704A1 (fr) * | 1995-10-17 | 1997-04-24 | Suntory Limited | Medicament contre la thrombopenie |
| US9861346B2 (en) | 2003-07-14 | 2018-01-09 | W. L. Gore & Associates, Inc. | Patent foramen ovale (PFO) closure device with linearly elongating petals |
| JP2007519609A (ja) * | 2003-09-17 | 2007-07-19 | アイコス コーポレイション | 細胞増殖を制御するためのｃｈｋ１インヒビターの使用 |
| US9005242B2 (en) | 2007-04-05 | 2015-04-14 | W.L. Gore & Associates, Inc. | Septal closure device with centering mechanism |
| US20130165967A1 (en) | 2008-03-07 | 2013-06-27 | W.L. Gore & Associates, Inc. | Heart occlusion devices |
| US20120029556A1 (en) | 2009-06-22 | 2012-02-02 | Masters Steven J | Sealing device and delivery system |
| US8956389B2 (en) | 2009-06-22 | 2015-02-17 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
| US10828019B2 (en) | 2013-01-18 | 2020-11-10 | W.L. Gore & Associates, Inc. | Sealing device and delivery system |
| US9808230B2 (en) | 2014-06-06 | 2017-11-07 | W. L. Gore & Associates, Inc. | Sealing device and delivery system |
| CN113262293B (zh) * | 2020-02-17 | 2022-11-08 | 中国医学科学院医药生物技术研究所 | 一组具有抗病毒活性的肽类化合物奥米克欣及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3592925A (en) * | 1969-04-21 | 1971-07-13 | American Cyanamid Co | Antibiotics ah272alpha2 and ah272beta2 and process for producing same |
| US3907779A (en) * | 1974-05-20 | 1975-09-23 | Upjohn Co | 5,6 Dihydro-5-azathymidine and derivatives |
| AU574713B2 (en) * | 1983-09-12 | 1988-07-14 | Warner-Lambert Company | Cl-1957a antibiotic compound and its production |
| US4575500A (en) * | 1984-03-26 | 1986-03-11 | Merck & Co., Inc. | Antifungal substances and process for their production |
| JPH02186A (ja) * | 1987-05-07 | 1990-01-05 | Sumitomo Chem Co Ltd | 新規化合物およびそれを有効成分とする農工業用殺菌剤 |
| EP0329361B1 (en) * | 1988-02-13 | 1995-12-06 | Suntory Limited | 2-pyranone derivatives and process for production thereof |
| JP2865302B2 (ja) * | 1988-02-13 | 1999-03-08 | サントリー株式会社 | ２―ピラノン誘導体及びその製造法並びにそれを含む抗菌剤 |
| AU649116B2 (en) * | 1991-03-27 | 1994-05-12 | Sankyo Company Limited | New compounds, named the "Leustroducins", their preparation and their therapeutic uses |
-
1992
- 1992-03-24 AU AU13123/92A patent/AU649116B2/en not_active Ceased
- 1992-03-25 US US07/857,162 patent/US5334587A/en not_active Expired - Fee Related
- 1992-03-25 JP JP4066630A patent/JPH05123179A/ja active Pending
- 1992-03-25 HU HU9201005A patent/HU216875B/hu not_active IP Right Cessation
- 1992-03-25 NO NO921158A patent/NO304600B1/no not_active IP Right Cessation
- 1992-03-26 CA CA002064126A patent/CA2064126A1/en not_active Abandoned
- 1992-03-26 IS IS3829A patent/IS1604B/is unknown
- 1992-03-26 IE IE920965A patent/IE74389B1/en not_active IP Right Cessation
- 1992-03-26 CZ CS92915A patent/CZ279299B6/cs unknown
- 1992-03-26 FI FI921339A patent/FI101978B/fi active
- 1992-03-26 RU SU925011385A patent/RU2082760C1/ru active
- 1992-03-27 KR KR1019920005088A patent/KR0145680B1/ko not_active IP Right Cessation
- 1992-03-27 IL IL10139492A patent/IL101394A/he not_active IP Right Cessation
- 1992-03-27 CN CN92103126A patent/CN1058294C/zh not_active Expired - Lifetime
- 1992-03-27 TW TW081102373A patent/TW212182B/zh active
- 1992-03-27 AT AT92302718T patent/ATE134640T1/de not_active IP Right Cessation
- 1992-03-27 ES ES92302718T patent/ES2086651T3/es not_active Expired - Lifetime
- 1992-03-27 DE DE69208494T patent/DE69208494T2/de not_active Expired - Fee Related
- 1992-03-27 DK DK92302718.9T patent/DK0506463T3/da active
- 1992-03-27 NZ NZ242155A patent/NZ242155A/xx unknown
- 1992-03-27 EP EP92302718A patent/EP0506463B1/en not_active Expired - Lifetime
-
1994
- 1994-05-06 US US08/239,284 patent/US5443972A/en not_active Expired - Fee Related
-
1996
- 1996-05-20 GR GR960401371T patent/GR3019996T3/el unknown
- 1996-07-04 HK HK117696A patent/HK117696A/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
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| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |