IE56763B1 - Improvements in or relating to the synthesis of nizatidine - Google Patents

Improvements in or relating to the synthesis of nizatidine

Info

Publication number
IE56763B1
IE56763B1 IE274/84A IE27484A IE56763B1 IE 56763 B1 IE56763 B1 IE 56763B1 IE 274/84 A IE274/84 A IE 274/84A IE 27484 A IE27484 A IE 27484A IE 56763 B1 IE56763 B1 IE 56763B1
Authority
IE
Ireland
Prior art keywords
acid
methyl
nizatidine
isothiourea
product
Prior art date
Application number
IE274/84A
Other languages
English (en)
Other versions
IE840274L (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23843341&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE56763(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IE840274L publication Critical patent/IE840274L/en
Publication of IE56763B1 publication Critical patent/IE56763B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Credit Cards Or The Like (AREA)
IE274/84A 1983-02-07 1984-02-06 Improvements in or relating to the synthesis of nizatidine IE56763B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46429683A 1983-02-07 1983-02-07

Publications (2)

Publication Number Publication Date
IE840274L IE840274L (en) 1984-08-07
IE56763B1 true IE56763B1 (en) 1991-12-04

Family

ID=23843341

Family Applications (1)

Application Number Title Priority Date Filing Date
IE274/84A IE56763B1 (en) 1983-02-07 1984-02-06 Improvements in or relating to the synthesis of nizatidine

Country Status (27)

Country Link
EP (1) EP0116452B1 (US06380249-20020430-C00197.png)
JP (1) JPS59152378A (US06380249-20020430-C00197.png)
KR (1) KR860000767B1 (US06380249-20020430-C00197.png)
AT (1) ATE84530T1 (US06380249-20020430-C00197.png)
AU (1) AU559639B2 (US06380249-20020430-C00197.png)
BG (1) BG45216A3 (US06380249-20020430-C00197.png)
CA (1) CA1221369A (US06380249-20020430-C00197.png)
CS (1) CS240994B2 (US06380249-20020430-C00197.png)
DD (1) DD216459A5 (US06380249-20020430-C00197.png)
DE (1) DE3486032T2 (US06380249-20020430-C00197.png)
DK (2) DK164501C (US06380249-20020430-C00197.png)
EG (1) EG17702A (US06380249-20020430-C00197.png)
ES (1) ES8601941A1 (US06380249-20020430-C00197.png)
FI (1) FI840474A (US06380249-20020430-C00197.png)
GB (1) GB2134521B (US06380249-20020430-C00197.png)
GR (1) GR81755B (US06380249-20020430-C00197.png)
HU (2) HU194198B (US06380249-20020430-C00197.png)
IE (1) IE56763B1 (US06380249-20020430-C00197.png)
IL (1) IL70880A (US06380249-20020430-C00197.png)
NZ (1) NZ207046A (US06380249-20020430-C00197.png)
PH (1) PH19941A (US06380249-20020430-C00197.png)
PL (1) PL138793B1 (US06380249-20020430-C00197.png)
PT (1) PT78063A (US06380249-20020430-C00197.png)
RO (1) RO87706A (US06380249-20020430-C00197.png)
SU (1) SU1303028A3 (US06380249-20020430-C00197.png)
UA (1) UA6020A1 (US06380249-20020430-C00197.png)
ZA (1) ZA84869B (US06380249-20020430-C00197.png)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL80961A0 (en) * 1985-12-18 1987-03-31 Lilly Co Eli Synthesis of nizatidine
ES2038922B1 (es) * 1991-12-30 1994-04-16 Fermentaciones Y Sintesis Espa Procedimiento para la obtencion de nizatidina.
US5470865A (en) * 1994-08-30 1995-11-28 Eli Lilly And Company Pharmaceutical composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200578A (en) * 1978-12-18 1980-04-29 Bristol-Myers Company Thiazole derivatives
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine

Also Published As

Publication number Publication date
KR840007591A (ko) 1984-12-08
GR81755B (US06380249-20020430-C00197.png) 1984-12-12
DD216459A5 (de) 1984-12-12
RO87706B (ro) 1985-10-01
SU1303028A3 (ru) 1987-04-07
IL70880A (en) 1987-01-30
CS81284A2 (en) 1985-06-13
JPS59152378A (ja) 1984-08-31
KR860000767B1 (ko) 1986-06-23
EP0116452A3 (en) 1987-04-29
DK164906B (da) 1992-09-07
FI840474A (fi) 1984-08-08
ES529492A0 (es) 1985-11-01
CS240994B2 (en) 1986-03-13
GB2134521A (en) 1984-08-15
EP0116452B1 (en) 1993-01-13
UA6020A1 (uk) 1994-12-29
IE840274L (en) 1984-08-07
BG45216A3 (US06380249-20020430-C00197.png) 1989-04-14
PT78063A (en) 1984-03-01
DK164501B (da) 1992-07-06
IL70880A0 (en) 1984-05-31
PH19941A (en) 1986-08-14
HU194198B (en) 1988-01-28
AU559639B2 (en) 1987-03-19
RO87706A (ro) 1985-10-31
ES8601941A1 (es) 1985-11-01
ATE84530T1 (de) 1993-01-15
DE3486032D1 (de) 1993-02-25
PL246097A1 (en) 1985-06-04
HU190527B (en) 1986-09-29
DK164906C (da) 1993-01-25
DK21292A (da) 1992-02-19
GB2134521B (en) 1986-10-01
PL138793B1 (en) 1986-11-29
DK51984D0 (da) 1984-02-06
ZA84869B (en) 1985-09-25
JPH0576473B2 (US06380249-20020430-C00197.png) 1993-10-22
AU2421584A (en) 1984-08-16
EP0116452A2 (en) 1984-08-22
DK21292D0 (da) 1992-02-19
DK51984A (da) 1984-08-08
NZ207046A (en) 1986-06-11
CA1221369A (en) 1987-05-05
DK164501C (da) 1992-11-23
GB8403109D0 (en) 1984-03-07
EG17702A (en) 1991-03-30
FI840474A0 (fi) 1984-02-06
DE3486032T2 (de) 1993-05-19

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