IE45877B1 - New derivatives of 9-chloroprednisolone - Google Patents

New derivatives of 9-chloroprednisolone

Info

Publication number
IE45877B1
IE45877B1 IE2011/77A IE201177A IE45877B1 IE 45877 B1 IE45877 B1 IE 45877B1 IE 2011/77 A IE2011/77 A IE 2011/77A IE 201177 A IE201177 A IE 201177A IE 45877 B1 IE45877 B1 IE 45877B1
Authority
IE
Ireland
Prior art keywords
dione
pregnadiene
lip
hydroxy
chloro
Prior art date
Application number
IE2011/77A
Other languages
English (en)
Other versions
IE45877L (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2645105A external-priority patent/DE2645105C2/de
Priority claimed from DE19772742982 external-priority patent/DE2742982C2/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of IE45877L publication Critical patent/IE45877L/xx
Publication of IE45877B1 publication Critical patent/IE45877B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IE2011/77A 1976-10-04 1977-10-03 New derivatives of 9-chloroprednisolone IE45877B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2645105A DE2645105C2 (de) 1976-10-04 1976-10-04 Derivate des 9-Chlorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Präparat
DE19772742982 DE2742982C2 (de) 1977-09-21 1977-09-21 9-Chlorprednisolon-Derivate, Verfahren zu deren Herstellung und diese enthaltendes pharmazeutisches Präparat

Publications (2)

Publication Number Publication Date
IE45877L IE45877L (en) 1978-04-04
IE45877B1 true IE45877B1 (en) 1982-12-15

Family

ID=25770978

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2011/77A IE45877B1 (en) 1976-10-04 1977-10-03 New derivatives of 9-chloroprednisolone

Country Status (21)

Country Link
JP (1) JPS5359654A (cg-RX-API-DMAC10.html)
AT (1) AT358202B (cg-RX-API-DMAC10.html)
CH (4) CH630098A5 (cg-RX-API-DMAC10.html)
DK (1) DK438277A (cg-RX-API-DMAC10.html)
ES (1) ES462887A1 (cg-RX-API-DMAC10.html)
FI (1) FI58645C (cg-RX-API-DMAC10.html)
FR (1) FR2366313A1 (cg-RX-API-DMAC10.html)
GB (1) GB1594852A (cg-RX-API-DMAC10.html)
GR (1) GR73041B (cg-RX-API-DMAC10.html)
HU (1) HU179593B (cg-RX-API-DMAC10.html)
IE (1) IE45877B1 (cg-RX-API-DMAC10.html)
IL (1) IL53030A (cg-RX-API-DMAC10.html)
IT (1) IT1113623B (cg-RX-API-DMAC10.html)
LU (1) LU78223A1 (cg-RX-API-DMAC10.html)
NL (1) NL7710869A (cg-RX-API-DMAC10.html)
NO (1) NO148597C (cg-RX-API-DMAC10.html)
NZ (1) NZ185295A (cg-RX-API-DMAC10.html)
PL (1) PL110392B1 (cg-RX-API-DMAC10.html)
PT (1) PT67109B (cg-RX-API-DMAC10.html)
SE (1) SE431655B (cg-RX-API-DMAC10.html)
SU (2) SU743581A3 (cg-RX-API-DMAC10.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (de) * 1978-12-11 1980-06-19 Schering Ag Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung
JPH0374245A (ja) * 1989-08-12 1991-03-28 Mk Seiko Co Ltd 洗車機
KR20150055082A (ko) 2010-03-26 2015-05-20 갈데르마 리써어치 앤드 디벨로프먼트 홍반의 유효하고 안전한 치료를 위한 개선된 방법 및 조성물
KR20140091543A (ko) 2011-10-19 2014-07-21 갈데르마 소시에떼아노님 전신용인 포스포디에스터레이즈타입-5-억제제에 의한 안면홍조를 경감시키는 방법
CN106632561A (zh) * 2016-12-16 2017-05-10 广州仁恒医药科技股份有限公司 一种二氟泼尼酯的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1195748B (de) * 1961-06-24 1965-07-01 Vismara Francesco Spa Verfahren zur Herstellung von 1'-substituierten 17alpha, 21-(1'-Alkoxy)-methylendioxysterioden
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

Also Published As

Publication number Publication date
FI58645C (fi) 1981-03-10
NO148597B (no) 1983-08-01
HU179593B (en) 1982-11-29
SU743581A3 (ru) 1980-06-25
JPS6129960B2 (cg-RX-API-DMAC10.html) 1986-07-10
SE431655B (sv) 1984-02-20
CH632772A5 (en) 1982-10-29
IL53030A0 (en) 1977-11-30
NL7710869A (nl) 1978-04-06
DK438277A (da) 1978-04-05
NZ185295A (en) 1980-04-28
IE45877L (en) 1978-04-04
GB1594852A (en) 1981-08-05
FI772922A7 (fi) 1978-04-05
ATA703577A (de) 1980-01-15
FI58645B (fi) 1980-11-28
SU751327A3 (ru) 1980-07-23
GR73041B (cg-RX-API-DMAC10.html) 1984-01-26
FR2366313A1 (fr) 1978-04-28
JPS5359654A (en) 1978-05-29
SE7711039L (sv) 1978-04-05
CH631997A5 (en) 1982-09-15
AT358202B (de) 1980-08-25
CH632278A5 (en) 1982-09-30
PL201161A1 (pl) 1979-01-29
PT67109A (de) 1977-11-01
FR2366313B1 (cg-RX-API-DMAC10.html) 1980-02-01
IT1113623B (it) 1986-01-20
IL53030A (en) 1982-11-30
NO773362L (no) 1978-04-05
NO148597C (no) 1983-11-09
CH630098A5 (en) 1982-05-28
PL110392B1 (en) 1980-07-31
ES462887A1 (es) 1978-12-16
LU78223A1 (cg-RX-API-DMAC10.html) 1978-02-01
PT67109B (de) 1979-03-14

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