IE42208B1 - 3-amino-indazlecarboxylic acid derivatives,process for their preparation and their use as medicaments - Google Patents

3-amino-indazlecarboxylic acid derivatives,process for their preparation and their use as medicaments

Info

Publication number
IE42208B1
IE42208B1 IE2714/75A IE271475A IE42208B1 IE 42208 B1 IE42208 B1 IE 42208B1 IE 2714/75 A IE2714/75 A IE 2714/75A IE 271475 A IE271475 A IE 271475A IE 42208 B1 IE42208 B1 IE 42208B1
Authority
IE
Ireland
Prior art keywords
amino
compound
indazole
formula
salt
Prior art date
Application number
IE2714/75A
Other languages
English (en)
Other versions
IE42208L (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IE42208L publication Critical patent/IE42208L/xx
Publication of IE42208B1 publication Critical patent/IE42208B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IE2714/75A 1974-12-13 1975-12-12 3-amino-indazlecarboxylic acid derivatives,process for their preparation and their use as medicaments IE42208B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2458965A DE2458965C3 (de) 1974-12-13 1974-12-13 3-Amino-indazol-N-carbonsäure-Derivate, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
IE42208L IE42208L (en) 1976-06-13
IE42208B1 true IE42208B1 (en) 1980-06-18

Family

ID=5933305

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2714/75A IE42208B1 (en) 1974-12-13 1975-12-12 3-amino-indazlecarboxylic acid derivatives,process for their preparation and their use as medicaments

Country Status (27)

Country Link
US (1) US4051252A (enExample)
JP (1) JPS5182266A (enExample)
AT (1) AT343653B (enExample)
BE (1) BE836528A (enExample)
CA (1) CA1059523A (enExample)
CH (1) CH622250A5 (enExample)
CS (1) CS189731B2 (enExample)
DD (1) DD125484A5 (enExample)
DE (1) DE2458965C3 (enExample)
DK (1) DK137082C (enExample)
ES (1) ES443429A1 (enExample)
FI (1) FI753493A7 (enExample)
FR (1) FR2293928A1 (enExample)
GB (1) GB1490306A (enExample)
HK (1) HK52580A (enExample)
HU (1) HU173557B (enExample)
IE (1) IE42208B1 (enExample)
IL (1) IL48642A (enExample)
KE (1) KE3078A (enExample)
LU (1) LU73993A1 (enExample)
NL (1) NL7514521A (enExample)
NO (1) NO145382C (enExample)
PL (1) PL99858B1 (enExample)
SE (1) SE419645B (enExample)
SU (1) SU604487A3 (enExample)
YU (1) YU315275A (enExample)
ZA (1) ZA757777B (enExample)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431657A (en) * 1982-05-24 1984-02-14 Ayerst, Mckenna & Harrison Inc. Analgesic compositions consisting of 2H-benzothieno[3,2-c]pyrazol-3-amine derivatives
KR20010086657A (ko) * 2000-03-02 2001-09-15 성재갑 아미노인다졸 유도체 및 이를 함유하는 싸이클린 의존키나아제 저해제 조성물
ZA200301701B (en) * 2000-09-15 2004-03-01 Vertex Pharma Pyrazole compounds useful as protein kinase inhibitors.
US6660731B2 (en) 2000-09-15 2003-12-09 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
WO2002022605A1 (en) 2000-09-15 2002-03-21 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
SI1318997T1 (sl) * 2000-09-15 2006-12-31 Vertex Pharma Pirazolne spojine, uporabne kot inhibitorji protein-kinaze
US7473691B2 (en) * 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6989385B2 (en) 2000-12-21 2006-01-24 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
KR100406634B1 (ko) * 2001-03-12 2003-11-20 주식회사 엘지생명과학 3,5-디아미노인다졸 유도체, 그의 제조방법 및 사이클린의존성 키나아제 저해제로서의 그의 용도
BR0212841A (pt) 2001-09-26 2004-08-03 Pharmacia Italia Spa Derivado ativo de aminoindazole como inibidores de cinase, processo para sua preparação e composições farmacêuticas que os contém
WO2003066629A2 (en) * 2002-02-06 2003-08-14 Vertex Pharmaceuticals Incorporated Heteroaryl compounds useful as inhibitors of gsk-3
FR2836915B1 (fr) * 2002-03-11 2008-01-11 Aventis Pharma Sa Derives d'aminoindazoles, procede de preparation et intermediaires de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
US20040009981A1 (en) 2002-03-15 2004-01-15 David Bebbington Compositions useful as inhibitors of protein kinases
MXPA04011417A (es) 2002-05-17 2005-02-14 Pharmacia Italia Spa Derivados de aminoindazol activos como inhibidores de cinasa, procedimiento para su preparacion y composiciones farmaceuticas que los comprenden.
MY141867A (en) 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
CN1319968C (zh) 2002-08-02 2007-06-06 沃泰克斯药物股份有限公司 用作gsk－3的抑制剂的吡唑组合物
WO2004041285A1 (en) * 2002-10-31 2004-05-21 Amgen Inc. Antiinflammation agents
US7601718B2 (en) 2003-02-06 2009-10-13 Vertex Pharmaceuticals Incorporated Compositions useful as inhibitors of protein kinases
US7592340B2 (en) * 2003-12-04 2009-09-22 Vertex Pharmaceuticals Incorporated Quinoxalines useful as inhibitors of protein kinases
DE102004005172A1 (de) * 2004-02-02 2005-08-18 Aventis Pharma Deutschland Gmbh Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
ATE542814T1 (de) 2005-08-18 2012-02-15 Vertex Pharma Pyrazinkinaseinhibitoren
MX2008005814A (es) * 2005-11-03 2008-10-15 Vertex Pharma Aminopirimidinas utiles como inhibidores de cinasa.
ES2385404T3 (es) * 2006-04-14 2012-07-24 Abbott Laboratories Procedimiento para la preparación de ureas de indazolilo que inhiben los receptores vaniloides de subtipo 1 (VR1)
CA2668429A1 (en) 2006-11-02 2008-05-15 Vertex Pharmaceuticals Incorporated Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases
ES2347721T3 (es) 2006-12-19 2010-11-03 Vertex Pharmaceuticals, Inc. Aminopirimidinas utiles como inhibidores de proteina quinasas.
AU2008226457B2 (en) 2007-03-09 2014-03-20 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as inhibitors of protein kinases
EP2137183B1 (en) 2007-03-09 2011-09-28 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as inhibitors of protein kinases
EP2134709A1 (en) 2007-03-09 2009-12-23 Vertex Pharmaceuticals, Inc. Aminopyridines useful as inhibitors of protein kinases
NZ580343A (en) 2007-04-13 2012-03-30 Vertex Pharma Aminopyrimidines useful as kinase inhibitors
JP5389785B2 (ja) 2007-05-02 2014-01-15 バーテックス ファーマシューティカルズ インコーポレイテッド キナーゼ阻害剤として有用なチアゾールおよびピラゾール
MX2009011811A (es) * 2007-05-02 2010-01-14 Vertex Pharma Aminopirimidinas utiles como inhibidores de cinasa.
CA2694381A1 (en) 2007-05-02 2008-11-13 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
EP2164842A2 (en) * 2007-05-24 2010-03-24 Vertex Pharmaceuticals Incorporated Thiazoles and pyrazoles useful as kinase inhibitors
NZ582879A (en) * 2007-07-31 2012-03-30 Vertex Pharma Process for preparing 5-fluoro-1h-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof
MX2011002312A (es) * 2008-09-03 2011-04-26 Vertex Pharma Co-cristales y formulaciones farmaceuticas que comprenden los mismos.
DE102009004245A1 (de) 2009-01-09 2010-07-15 Bayer Schering Pharma Aktiengesellschaft Neue anellierte, Heteroatom-verbrückte Pyrazol- und Imidazol-Derivate und ihre Verwendung
WO2014017936A2 (en) 2012-07-24 2014-01-30 Bial- Portela & Ca, S.A. Urea compounds and their use as enzyme inhibitors
JP2015528013A (ja) * 2012-07-27 2015-09-24 ビアル−ポルテラ エ コンパニア，ソシエダッド アノニマ 置換ウレア化合物の合成方法
AU2014293731B2 (en) 2013-07-24 2018-03-08 Bial - Portela & Ca, S.A. Imidazolecarboxamides and their use as FAAH inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3133081A (en) * 1964-05-12 J-aminoindazole derivatives
CH397698A (de) * 1961-09-08 1965-08-31 Siegfried Ag Verfahren zur Herstellung neuer 1-Carbamyl-indazole
US3277100A (en) * 1963-05-31 1966-10-04 Du Pont Novel substituted pyrazoles
NL6707299A (enExample) * 1966-07-16 1968-01-17
DE1770649A1 (de) * 1968-06-15 1971-11-11 Bayer Ag Substituierte 3-Amino-indazole

Also Published As

Publication number Publication date
AT343653B (de) 1978-06-12
IE42208L (en) 1976-06-13
SU604487A3 (ru) 1978-04-25
AU8717075A (en) 1977-06-09
NO145382C (no) 1982-03-10
ATA939775A (de) 1977-10-15
DD125484A5 (enExample) 1977-04-20
IL48642A0 (en) 1976-02-29
FR2293928A1 (fr) 1976-07-09
HK52580A (en) 1980-09-26
YU315275A (en) 1982-02-28
CA1059523A (en) 1979-07-31
DE2458965A1 (de) 1976-06-16
GB1490306A (en) 1977-11-02
FI753493A7 (enExample) 1976-06-14
SE7513990L (sv) 1976-06-14
NL7514521A (nl) 1976-06-15
DE2458965C3 (de) 1979-10-11
SE419645B (sv) 1981-08-17
ES443429A1 (es) 1977-04-16
NO754024L (enExample) 1976-06-15
LU73993A1 (enExample) 1976-11-11
CH622250A5 (enExample) 1981-03-31
FR2293928B1 (enExample) 1979-09-21
DK137082B (da) 1978-01-16
DE2458965B2 (de) 1979-02-22
JPS5182266A (en) 1976-07-19
US4051252A (en) 1977-09-27
PL99858B1 (pl) 1978-08-31
IL48642A (en) 1979-12-30
DK137082C (da) 1978-06-19
NO145382B (no) 1981-11-30
DK567275A (da) 1976-06-14
ZA757777B (en) 1976-11-24
KE3078A (en) 1980-10-03
CS189731B2 (en) 1979-04-30
BE836528A (fr) 1976-06-11
HU173557B (hu) 1979-06-28

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