IE42130B1 - Substituted imidazolidines and pharmaceutical uses thereof - Google Patents
Substituted imidazolidines and pharmaceutical uses thereofInfo
- Publication number
- IE42130B1 IE42130B1 IE2150/75A IE215075A IE42130B1 IE 42130 B1 IE42130 B1 IE 42130B1 IE 2150/75 A IE2150/75 A IE 2150/75A IE 215075 A IE215075 A IE 215075A IE 42130 B1 IE42130 B1 IE 42130B1
- Authority
- IE
- Ireland
- Prior art keywords
- compound
- formula
- acid addition
- effected
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2446758A DE2446758C3 (de) | 1974-10-01 | 1974-10-01 | 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE42130L IE42130L (en) | 1976-04-01 |
| IE42130B1 true IE42130B1 (en) | 1980-06-04 |
Family
ID=5927202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2150/75A IE42130B1 (en) | 1974-10-01 | 1975-10-01 | Substituted imidazolidines and pharmaceutical uses thereof |
Country Status (27)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2630060C2 (de) * | 1976-07-03 | 1984-04-19 | C.H. Boehringer Sohn, 6507 Ingelheim | 2-(2-Brom-6-fluor-phenylimino)-imidazolidin, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung |
| DE2806811A1 (de) * | 1978-02-17 | 1979-08-23 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben |
| DE2806775A1 (de) * | 1978-02-17 | 1979-08-30 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
| ZA801680B (en) * | 1979-04-03 | 1981-03-25 | Fujisawa Pharmaceutical Co | 2-imidazoline derivatives,process for the preparation thereof and the pharmaceutical composition of the same |
| HU192986B (en) * | 1984-05-23 | 1987-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for production of imidasodiline derivatives |
| JP2009524619A (ja) * | 2006-01-27 | 2009-07-02 | エフ．ホフマン−ラ ロシュ アーゲー | Ｃｎｓ障害の処置のための２−イミダゾールの使用 |
| KR101275405B1 (ko) | 2007-02-02 | 2013-06-17 | 에프. 호프만-라 로슈 아게 | 중추 신경계 장애의 치료용 ｔａａｒ1 리간드로서 2-아미노옥사졸린 |
| KR101335845B1 (ko) | 2007-02-15 | 2013-12-02 | 에프. 호프만-라 로슈 아게 | Ｔａａｒ1 리간드로서의 2-아미노옥사졸린 |
| US8242153B2 (en) | 2008-07-24 | 2012-08-14 | Hoffmann-La Roche Inc. | 4,5-dihydro-oxazol-2YL derivatives |
| US8354441B2 (en) | 2009-11-11 | 2013-01-15 | Hoffmann-La Roche Inc. | Oxazoline derivatives |
| US9452980B2 (en) | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
| HUE050986T2 (hu) | 2016-03-17 | 2021-01-28 | Hoffmann La Roche | 5-etil-4-metil-pirazol-3-karboxamid származék, amely TAAR-agonista aktivitású |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3236857A (en) * | 1961-10-09 | 1966-02-22 | Boehringer Sohn Ingelheim | 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products |
| DE1670807A1 (de) * | 1967-02-17 | 1971-03-11 | Bayer Ag | Verfahren zur Herstellung von cyclischen Guanidinen |
| DE1670918A1 (de) * | 1967-09-07 | 1971-04-08 | Bayer Ag | Verfahren zur Herstellung von 2-Aryl-amino-substituierten stickstoffhaltigen Heterocyclen |
| BE787683A (fr) * | 1971-08-20 | 1973-02-19 | Boehringer Sohn Ingelheim | 2-phenylimino-imidazolidines, leurs sels d'addition avec des acides et procedes pour les fabriquer |
-
1974
- 1974-10-01 DE DE2446758A patent/DE2446758C3/de not_active Expired
-
1975
- 1975-09-22 AT AT722875A patent/AT344159B/de not_active IP Right Cessation
- 1975-09-23 SU SU7502174605A patent/SU575026A3/ru active
- 1975-09-26 PH PH17613A patent/PH13653A/en unknown
- 1975-09-29 BG BG7500032014A patent/BG25221A3/xx unknown
- 1975-09-29 LU LU73472A patent/LU73472A1/xx unknown
- 1975-09-29 CS CS756573A patent/CS193524B2/cs unknown
- 1975-09-29 DD DD188613A patent/DD123602A5/xx unknown
- 1975-09-29 BG BG7500031110A patent/BG25220A3/xx unknown
- 1975-09-30 NO NO753314A patent/NO143459C/no unknown
- 1975-09-30 NL NL7511490A patent/NL7511490A/xx not_active Application Discontinuation
- 1975-09-30 FI FI752728A patent/FI61883C/fi not_active IP Right Cessation
- 1975-09-30 ZA ZA756185A patent/ZA756185B/xx unknown
- 1975-09-30 CA CA236,670A patent/CA1056836A/en not_active Expired
- 1975-09-30 IL IL48214A patent/IL48214A/xx unknown
- 1975-09-30 JP JP50118196A patent/JPS6018653B2/ja not_active Expired
- 1975-09-30 PL PL1975197816A patent/PL98984B1/pl unknown
- 1975-09-30 CH CH1267875A patent/CH620682A5/de not_active IP Right Cessation
- 1975-09-30 ES ES441385A patent/ES441385A1/es not_active Expired
- 1975-09-30 HU HU75BO1573A patent/HU178469B/hu unknown
- 1975-09-30 GB GB40012/75A patent/GB1515019A/en not_active Expired
- 1975-09-30 NZ NZ178810A patent/NZ178810A/xx unknown
- 1975-09-30 BE BE160578A patent/BE834051A/xx not_active IP Right Cessation
- 1975-09-30 PL PL1975183670A patent/PL97003B1/pl unknown
- 1975-09-30 DK DK441875A patent/DK441875A/da not_active Application Discontinuation
- 1975-10-01 IE IE2150/75A patent/IE42130B1/en unknown
- 1975-10-01 FR FR7530117A patent/FR2286649A1/fr active Granted
- 1975-10-01 SE SE7511028A patent/SE418497B/xx not_active IP Right Cessation
-
1976
- 1976-02-04 ES ES444901A patent/ES444901A1/es not_active Expired
- 1976-02-04 ES ES444900A patent/ES444900A1/es not_active Expired
- 1976-02-04 ES ES444898A patent/ES444898A1/es not_active Expired
-
1980
- 1980-07-01 CH CH506580A patent/CH627454A5/de not_active IP Right Cessation
- 1980-07-01 CH CH506380A patent/CH627453A5/de not_active IP Right Cessation
- 1980-07-01 CH CH506280A patent/CH627452A5/de not_active IP Right Cessation
- 1980-07-01 CH CH506480A patent/CH626352A5/de not_active IP Right Cessation
-
1981
- 1981-09-24 YU YU02302/81A patent/YU230281A/xx unknown
Also Published As
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