JPS5159863A - Shinkina 2 66 jichikan 22 fueniruimino imidazorijin oyobi sonosanfukaenno seizohoho - Google Patents

Shinkina 2 66 jichikan 22 fueniruimino imidazorijin oyobi sonosanfukaenno seizohoho

Info

Publication number
JPS5159863A
JPS5159863A JP50118196A JP11819675A JPS5159863A JP S5159863 A JPS5159863 A JP S5159863A JP 50118196 A JP50118196 A JP 50118196A JP 11819675 A JP11819675 A JP 11819675A JP S5159863 A JPS5159863 A JP S5159863A
Authority
JP
Japan
Prior art keywords
sonosanfukaenno
shinkina
jichikan
imidazorijin
fueniruimino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP50118196A
Other languages
Japanese (ja)
Other versions
JPS6018653B2 (en
Inventor
Shutaare Herumuuto
Koope Heruberuto
Kunmeru Beruneku
Hoefuke Borufuganku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of JPS5159863A publication Critical patent/JPS5159863A/en
Publication of JPS6018653B2 publication Critical patent/JPS6018653B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP50118196A 1974-10-01 1975-09-30 Process for producing novel 2,6-disubstituted 2-phenylimino-imidazolidine and its acid addition salt Expired JPS6018653B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2446758A DE2446758C3 (en) 1974-10-01 1974-10-01 2- (2-Fluoro-6-trifluoromethylphenylimino) -imidazolidine, its acid addition salts, processes for the preparation of these compounds and their use in combating hypertension
DE2446758.1 1974-10-01

Publications (2)

Publication Number Publication Date
JPS5159863A true JPS5159863A (en) 1976-05-25
JPS6018653B2 JPS6018653B2 (en) 1985-05-11

Family

ID=5927202

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50118196A Expired JPS6018653B2 (en) 1974-10-01 1975-09-30 Process for producing novel 2,6-disubstituted 2-phenylimino-imidazolidine and its acid addition salt

Country Status (27)

Country Link
JP (1) JPS6018653B2 (en)
AT (1) AT344159B (en)
BE (1) BE834051A (en)
BG (2) BG25221A3 (en)
CA (1) CA1056836A (en)
CH (5) CH620682A5 (en)
CS (1) CS193524B2 (en)
DD (1) DD123602A5 (en)
DE (1) DE2446758C3 (en)
DK (1) DK441875A (en)
ES (4) ES441385A1 (en)
FI (1) FI61883C (en)
FR (1) FR2286649A1 (en)
GB (1) GB1515019A (en)
HU (1) HU178469B (en)
IE (1) IE42130B1 (en)
IL (1) IL48214A (en)
LU (1) LU73472A1 (en)
NL (1) NL7511490A (en)
NO (1) NO143459C (en)
NZ (1) NZ178810A (en)
PH (1) PH13653A (en)
PL (2) PL98984B1 (en)
SE (1) SE418497B (en)
SU (1) SU575026A3 (en)
YU (1) YU230281A (en)
ZA (1) ZA756185B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55136266A (en) * 1979-04-03 1980-10-23 Fujisawa Pharmaceut Co Ltd Derivatives of 2-imidazoline
JPS60255773A (en) * 1984-05-23 1985-12-17 エジス　ジヨジセルジヤール Preparation of imidazolidine derivative
JP2009524619A (en) * 2006-01-27 2009-07-02 エフ．ホフマン−ラ ロシュ アーゲー Use of 2-imidazole for the treatment of CNS disorders

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2630060C2 (en) * 1976-07-03 1984-04-19 C.H. Boehringer Sohn, 6507 Ingelheim 2- (2-Bromo-6-fluoro-phenylimino) -imidazolidine, its acid addition salts, medicaments containing them and processes for their preparation
DE2806811A1 (en) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim NEW SUBSTITUTED 2-PHENYLIMINO-IMIDAZOLIDINE, THEIR ACID-ADDITIONAL SALTS, THESE MEDICINAL PRODUCTS AND METHOD FOR MANUFACTURING THE SAME
DE2806775A1 (en) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim NEW SUBSTITUTED 2-PHENYLIMINO IMIDAZOLIDINE THEIR ACID ADDITION SALTS, MEDICINAL PRODUCTS CONTAINING THEM AND METHOD FOR THE PRODUCTION THEREOF
RU2473545C2 (en) 2007-02-02 2013-01-27 Ф.Хоффманн-Ля Рош Аг New 2-aminooxazolines as taar1 ligands for cns diseases
MX2009008465A (en) 2007-02-15 2009-08-20 Hoffmann La Roche 2-aminooxazolines as taar1 ligands.
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
CR20180443A (en) 2016-03-17 2018-11-21 Hoffmann La Roche MORPHOLINE DERIVATIVE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE1670807A1 (en) * 1967-02-17 1971-03-11 Bayer Ag Process for the preparation of cyclic guanidines
DE1670918A1 (en) * 1967-09-07 1971-04-08 Bayer Ag Process for the preparation of 2-aryl-amino-substituted nitrogen-containing heterocycles
BE787683A (en) * 1971-08-20 1973-02-19 Boehringer Sohn Ingelheim 2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ADDITIONAL SALTS WITH ACIDS AND METHODS FOR MAKING THEM

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55136266A (en) * 1979-04-03 1980-10-23 Fujisawa Pharmaceut Co Ltd Derivatives of 2-imidazoline
JPH0210830B2 (en) * 1979-04-03 1990-03-09 Fujisawa Pharmaceutical Co
JPS60255773A (en) * 1984-05-23 1985-12-17 エジス　ジヨジセルジヤール Preparation of imidazolidine derivative
JP2009524619A (en) * 2006-01-27 2009-07-02 エフ．ホフマン−ラ ロシュ アーゲー Use of 2-imidazole for the treatment of CNS disorders

Also Published As

Publication number Publication date
BG25220A3 (en) 1978-08-10
NO143459C (en) 1981-02-18
CH627453A5 (en) 1982-01-15
NL7511490A (en) 1976-04-05
DD123602A5 (en) 1977-01-05
BG25221A3 (en) 1978-08-10
CA1056836A (en) 1979-06-19
CH627452A5 (en) 1982-01-15
DE2446758C3 (en) 1979-01-04
YU230281A (en) 1982-02-28
FR2286649A1 (en) 1976-04-30
IL48214A0 (en) 1975-11-25
SE418497B (en) 1981-06-09
ZA756185B (en) 1977-06-29
ES444901A1 (en) 1977-04-16
NZ178810A (en) 1978-04-03
ES444898A1 (en) 1977-05-16
NO143459B (en) 1980-11-10
FI61883C (en) 1982-10-11
CS193524B2 (en) 1979-10-31
LU73472A1 (en) 1977-05-16
SU575026A3 (en) 1977-09-30
NO753314L (en) 1976-04-02
IE42130B1 (en) 1980-06-04
ATA722875A (en) 1977-11-15
IL48214A (en) 1979-10-31
FI61883B (en) 1982-06-30
JPS6018653B2 (en) 1985-05-11
IE42130L (en) 1976-04-01
DK441875A (en) 1976-04-02
CH627454A5 (en) 1982-01-15
DE2446758B2 (en) 1978-05-18
PH13653A (en) 1980-08-21
FI752728A (en) 1976-04-02
AT344159B (en) 1978-07-10
CH620682A5 (en) 1980-12-15
CH626352A5 (en) 1981-11-13
AU8529875A (en) 1977-04-07
PL97003B1 (en) 1978-01-31
GB1515019A (en) 1978-06-21
DE2446758A1 (en) 1976-04-22
BE834051A (en) 1976-03-30
FR2286649B1 (en) 1979-09-14
SE7511028L (en) 1976-04-02
PL98984B1 (en) 1978-06-30
ES444900A1 (en) 1977-04-16
ES441385A1 (en) 1977-08-01
HU178469B (en) 1982-05-28

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