ZA756185B - Improvements relating to 2,6-disubstituted 2-phenylimino imidazolidines - Google Patents

Improvements relating to 2,6-disubstituted 2-phenylimino imidazolidines

Info

Publication number
ZA756185B
ZA756185B ZA756185A ZA756185A ZA756185B ZA 756185 B ZA756185 B ZA 756185B ZA 756185 A ZA756185 A ZA 756185A ZA 756185 A ZA756185 A ZA 756185A ZA 756185 B ZA756185 B ZA 756185B
Authority
ZA
South Africa
Prior art keywords
imidazolidines
phenylimino
disubstituted
improvements relating
relating
Prior art date
Application number
ZA756185A
Inventor
H Staehle
W Hoefke
H Koeppe
W Kummer
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of ZA756185B publication Critical patent/ZA756185B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA756185A 1974-10-01 1975-09-30 Improvements relating to 2,6-disubstituted 2-phenylimino imidazolidines ZA756185B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2446758A DE2446758C3 (en) 1974-10-01 1974-10-01 2- (2-Fluoro-6-trifluoromethylphenylimino) -imidazolidine, its acid addition salts, processes for the preparation of these compounds and their use in combating hypertension

Publications (1)

Publication Number Publication Date
ZA756185B true ZA756185B (en) 1977-06-29

Family

ID=5927202

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA756185A ZA756185B (en) 1974-10-01 1975-09-30 Improvements relating to 2,6-disubstituted 2-phenylimino imidazolidines

Country Status (27)

Country Link
JP (1) JPS6018653B2 (en)
AT (1) AT344159B (en)
BE (1) BE834051A (en)
BG (2) BG25220A3 (en)
CA (1) CA1056836A (en)
CH (5) CH620682A5 (en)
CS (1) CS193524B2 (en)
DD (1) DD123602A5 (en)
DE (1) DE2446758C3 (en)
DK (1) DK441875A (en)
ES (4) ES441385A1 (en)
FI (1) FI61883C (en)
FR (1) FR2286649A1 (en)
GB (1) GB1515019A (en)
HU (1) HU178469B (en)
IE (1) IE42130B1 (en)
IL (1) IL48214A (en)
LU (1) LU73472A1 (en)
NL (1) NL7511490A (en)
NO (1) NO143459C (en)
NZ (1) NZ178810A (en)
PH (1) PH13653A (en)
PL (2) PL98984B1 (en)
SE (1) SE418497B (en)
SU (1) SU575026A3 (en)
YU (1) YU230281A (en)
ZA (1) ZA756185B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2630060C2 (en) * 1976-07-03 1984-04-19 C.H. Boehringer Sohn, 6507 Ingelheim 2- (2-Bromo-6-fluoro-phenylimino) -imidazolidine, its acid addition salts, medicaments containing them and processes for their preparation
DE2806811A1 (en) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim NEW SUBSTITUTED 2-PHENYLIMINO-IMIDAZOLIDINE, THEIR ACID-ADDITIONAL SALTS, THESE MEDICINAL PRODUCTS AND METHOD FOR MANUFACTURING THE SAME
DE2806775A1 (en) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim NEW SUBSTITUTED 2-PHENYLIMINO IMIDAZOLIDINE THEIR ACID ADDITION SALTS, MEDICINAL PRODUCTS CONTAINING THEM AND METHOD FOR THE PRODUCTION THEREOF
ZA801680B (en) * 1979-04-03 1981-03-25 Fujisawa Pharmaceutical Co 2-imidazoline derivatives,process for the preparation thereof and the pharmaceutical composition of the same
HU192986B (en) 1984-05-23 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of imidasodiline derivatives
JP2009524619A (en) * 2006-01-27 2009-07-02 エフ．ホフマン−ラ ロシュ アーゲー Use of 2-imidazole for the treatment of CNS disorders
KR101174191B1 (en) 2007-02-02 2012-08-14 에프. 호프만-라 로슈 아게 Novel 2-aminooxazolines as taar1 ligands for cns disorders
WO2008098857A1 (en) 2007-02-15 2008-08-21 F. Hoffmann-La Roche Ag 2-aminooxazolines as taar1 ligands
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
WO2017157873A1 (en) 2016-03-17 2017-09-21 F. Hoffmann-La Roche Ag 5-ethyl-4-methyl-pyrazole-3-carboxamide derivative having activity as agonist of taar

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE1670807A1 (en) * 1967-02-17 1971-03-11 Bayer Ag Process for the preparation of cyclic guanidines
DE1670918A1 (en) * 1967-09-07 1971-04-08 Bayer Ag Process for the preparation of 2-aryl-amino-substituted nitrogen-containing heterocycles
BE787683A (en) * 1971-08-20 1973-02-19 Boehringer Sohn Ingelheim 2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ADDITIONAL SALTS WITH ACIDS AND METHODS FOR MAKING THEM

Also Published As

Publication number Publication date
FR2286649B1 (en) 1979-09-14
CH626352A5 (en) 1981-11-13
ES441385A1 (en) 1977-08-01
DK441875A (en) 1976-04-02
PL97003B1 (en) 1978-01-31
IE42130L (en) 1976-04-01
CH627453A5 (en) 1982-01-15
CH620682A5 (en) 1980-12-15
PL98984B1 (en) 1978-06-30
NO753314L (en) 1976-04-02
GB1515019A (en) 1978-06-21
CA1056836A (en) 1979-06-19
ES444900A1 (en) 1977-04-16
NO143459C (en) 1981-02-18
JPS5159863A (en) 1976-05-25
ES444898A1 (en) 1977-05-16
AT344159B (en) 1978-07-10
FI752728A (en) 1976-04-02
AU8529875A (en) 1977-04-07
FR2286649A1 (en) 1976-04-30
YU230281A (en) 1982-02-28
ATA722875A (en) 1977-11-15
BG25221A3 (en) 1978-08-10
BE834051A (en) 1976-03-30
IE42130B1 (en) 1980-06-04
LU73472A1 (en) 1977-05-16
BG25220A3 (en) 1978-08-10
NZ178810A (en) 1978-04-03
IL48214A0 (en) 1975-11-25
DE2446758A1 (en) 1976-04-22
CH627454A5 (en) 1982-01-15
NO143459B (en) 1980-11-10
CH627452A5 (en) 1982-01-15
DE2446758C3 (en) 1979-01-04
DD123602A5 (en) 1977-01-05
DE2446758B2 (en) 1978-05-18
CS193524B2 (en) 1979-10-31
FI61883C (en) 1982-10-11
FI61883B (en) 1982-06-30
NL7511490A (en) 1976-04-05
SU575026A3 (en) 1977-09-30
IL48214A (en) 1979-10-31
SE7511028L (en) 1976-04-02
JPS6018653B2 (en) 1985-05-11
SE418497B (en) 1981-06-09
HU178469B (en) 1982-05-28
ES444901A1 (en) 1977-04-16
PH13653A (en) 1980-08-21

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