YU230281A - Process for preparing new 2,6-disubstituted 2-phenylimino -imidazolidines and acid addition salts thereof - Google Patents

Process for preparing new 2,6-disubstituted 2-phenylimino -imidazolidines and acid addition salts thereof

Info

Publication number
YU230281A
YU230281A YU02302/81A YU230281A YU230281A YU 230281 A YU230281 A YU 230281A YU 02302/81 A YU02302/81 A YU 02302/81A YU 230281 A YU230281 A YU 230281A YU 230281 A YU230281 A YU 230281A
Authority
YU
Yugoslavia
Prior art keywords
imidazolidines
phenylimino
disubstituted
acid addition
addition salts
Prior art date
Application number
YU02302/81A
Inventor
H Staehle
H Koeppe
W Kummer
W Hoefke
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of YU230281A publication Critical patent/YU230281A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/50Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
YU02302/81A 1974-10-01 1981-09-24 Process for preparing new 2,6-disubstituted 2-phenylimino -imidazolidines and acid addition salts thereof YU230281A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2446758A DE2446758C3 (en) 1974-10-01 1974-10-01 2- (2-Fluoro-6-trifluoromethylphenylimino) -imidazolidine, its acid addition salts, processes for the preparation of these compounds and their use in combating hypertension

Publications (1)

Publication Number Publication Date
YU230281A true YU230281A (en) 1982-02-28

Family

ID=5927202

Family Applications (1)

Application Number Title Priority Date Filing Date
YU02302/81A YU230281A (en) 1974-10-01 1981-09-24 Process for preparing new 2,6-disubstituted 2-phenylimino -imidazolidines and acid addition salts thereof

Country Status (27)

Country Link
JP (1) JPS6018653B2 (en)
AT (1) AT344159B (en)
BE (1) BE834051A (en)
BG (2) BG25220A3 (en)
CA (1) CA1056836A (en)
CH (5) CH620682A5 (en)
CS (1) CS193524B2 (en)
DD (1) DD123602A5 (en)
DE (1) DE2446758C3 (en)
DK (1) DK441875A (en)
ES (4) ES441385A1 (en)
FI (1) FI61883C (en)
FR (1) FR2286649A1 (en)
GB (1) GB1515019A (en)
HU (1) HU178469B (en)
IE (1) IE42130B1 (en)
IL (1) IL48214A (en)
LU (1) LU73472A1 (en)
NL (1) NL7511490A (en)
NO (1) NO143459C (en)
NZ (1) NZ178810A (en)
PH (1) PH13653A (en)
PL (2) PL97003B1 (en)
SE (1) SE418497B (en)
SU (1) SU575026A3 (en)
YU (1) YU230281A (en)
ZA (1) ZA756185B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2630060C2 (en) * 1976-07-03 1984-04-19 C.H. Boehringer Sohn, 6507 Ingelheim 2- (2-Bromo-6-fluoro-phenylimino) -imidazolidine, its acid addition salts, medicaments containing them and processes for their preparation
DE2806775A1 (en) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim NEW SUBSTITUTED 2-PHENYLIMINO IMIDAZOLIDINE THEIR ACID ADDITION SALTS, MEDICINAL PRODUCTS CONTAINING THEM AND METHOD FOR THE PRODUCTION THEREOF
DE2806811A1 (en) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim NEW SUBSTITUTED 2-PHENYLIMINO-IMIDAZOLIDINE, THEIR ACID-ADDITIONAL SALTS, THESE MEDICINAL PRODUCTS AND METHOD FOR MANUFACTURING THE SAME
ZA801680B (en) * 1979-04-03 1981-03-25 Fujisawa Pharmaceutical Co 2-imidazoline derivatives,process for the preparation thereof and the pharmaceutical composition of the same
HU192986B (en) 1984-05-23 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of imidasodiline derivatives
CA2637292A1 (en) * 2006-01-27 2007-08-16 F. Hoffmann-La Roche Ag Use of 2-imidazoles for the treatment of cns disorders
JP5248528B2 (en) 2007-02-02 2013-07-31 エフ.ホフマン−ラ ロシュ アーゲー Novel 2-aminooxazolines as TAAR1 ligands for CNS diseases
CA2676944C (en) 2007-02-15 2016-01-19 F. Hoffmann-La Roche Ag 2-aminooxazolines as taar1 ligands
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
SG11201807516UA (en) 2016-03-17 2018-09-27 Hoffmann La Roche 5-ethyl-4-methyl-pyrazole-3-carboxamide derivative having activity as agonist of taar

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE1670807A1 (en) * 1967-02-17 1971-03-11 Bayer Ag Process for the preparation of cyclic guanidines
DE1670918A1 (en) * 1967-09-07 1971-04-08 Bayer Ag Process for the preparation of 2-aryl-amino-substituted nitrogen-containing heterocycles
BE787683A (en) * 1971-08-20 1973-02-19 Boehringer Sohn Ingelheim 2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ADDITIONAL SALTS WITH ACIDS AND METHODS FOR MAKING THEM

Also Published As

Publication number Publication date
DD123602A5 (en) 1977-01-05
FR2286649A1 (en) 1976-04-30
FR2286649B1 (en) 1979-09-14
IE42130L (en) 1976-04-01
ES441385A1 (en) 1977-08-01
CH627454A5 (en) 1982-01-15
BE834051A (en) 1976-03-30
ES444898A1 (en) 1977-05-16
FI61883C (en) 1982-10-11
FI752728A (en) 1976-04-02
JPS5159863A (en) 1976-05-25
DE2446758C3 (en) 1979-01-04
NZ178810A (en) 1978-04-03
CS193524B2 (en) 1979-10-31
DE2446758A1 (en) 1976-04-22
PL97003B1 (en) 1978-01-31
ATA722875A (en) 1977-11-15
CH627453A5 (en) 1982-01-15
NO143459C (en) 1981-02-18
CH627452A5 (en) 1982-01-15
AU8529875A (en) 1977-04-07
BG25221A3 (en) 1978-08-10
IL48214A0 (en) 1975-11-25
SE418497B (en) 1981-06-09
ZA756185B (en) 1977-06-29
JPS6018653B2 (en) 1985-05-11
PL98984B1 (en) 1978-06-30
BG25220A3 (en) 1978-08-10
FI61883B (en) 1982-06-30
NO753314L (en) 1976-04-02
CH626352A5 (en) 1981-11-13
ES444900A1 (en) 1977-04-16
IE42130B1 (en) 1980-06-04
CA1056836A (en) 1979-06-19
DE2446758B2 (en) 1978-05-18
ES444901A1 (en) 1977-04-16
GB1515019A (en) 1978-06-21
SU575026A3 (en) 1977-09-30
PH13653A (en) 1980-08-21
HU178469B (en) 1982-05-28
DK441875A (en) 1976-04-02
SE7511028L (en) 1976-04-02
NO143459B (en) 1980-11-10
IL48214A (en) 1979-10-31
NL7511490A (en) 1976-04-05
AT344159B (en) 1978-07-10
LU73472A1 (en) 1977-05-16
CH620682A5 (en) 1980-12-15

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