ATA722875A - Verfahren zur herstellung neuer 2,6-disubstituierter 2-phenylimino-imidazolidine und ihrer saureadditionssalze - Google Patents

Verfahren zur herstellung neuer 2,6-disubstituierter 2-phenylimino-imidazolidine und ihrer saureadditionssalze

Info

Publication number
ATA722875A
ATA722875A AT722875A AT722875A ATA722875A AT A722875 A ATA722875 A AT A722875A AT 722875 A AT722875 A AT 722875A AT 722875 A AT722875 A AT 722875A AT A722875 A ATA722875 A AT A722875A
Authority
AT
Austria
Prior art keywords
phenylimino
imidazolidine
disubstituted
preparation
acid
Prior art date
Application number
AT722875A
Other languages
English (en)
Other versions
AT344159B (de
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of ATA722875A publication Critical patent/ATA722875A/de
Application granted granted Critical
Publication of AT344159B publication Critical patent/AT344159B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/50Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT722875A 1974-10-01 1975-09-22 Verfahren zur herstellung neuer 2,6-disubstituierter 2-phenylimino-imidazolidine und ihrer saeureadditionssalze AT344159B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2446758A DE2446758C3 (de) 1974-10-01 1974-10-01 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie

Publications (2)

Publication Number Publication Date
ATA722875A true ATA722875A (de) 1977-11-15
AT344159B AT344159B (de) 1978-07-10

Family

ID=5927202

Family Applications (1)

Application Number Title Priority Date Filing Date
AT722875A AT344159B (de) 1974-10-01 1975-09-22 Verfahren zur herstellung neuer 2,6-disubstituierter 2-phenylimino-imidazolidine und ihrer saeureadditionssalze

Country Status (27)

Country Link
JP (1) JPS6018653B2 (de)
AT (1) AT344159B (de)
BE (1) BE834051A (de)
BG (2) BG25221A3 (de)
CA (1) CA1056836A (de)
CH (5) CH620682A5 (de)
CS (1) CS193524B2 (de)
DD (1) DD123602A5 (de)
DE (1) DE2446758C3 (de)
DK (1) DK441875A (de)
ES (4) ES441385A1 (de)
FI (1) FI61883C (de)
FR (1) FR2286649A1 (de)
GB (1) GB1515019A (de)
HU (1) HU178469B (de)
IE (1) IE42130B1 (de)
IL (1) IL48214A (de)
LU (1) LU73472A1 (de)
NL (1) NL7511490A (de)
NO (1) NO143459C (de)
NZ (1) NZ178810A (de)
PH (1) PH13653A (de)
PL (2) PL97003B1 (de)
SE (1) SE418497B (de)
SU (1) SU575026A3 (de)
YU (1) YU230281A (de)
ZA (1) ZA756185B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2630060C2 (de) * 1976-07-03 1984-04-19 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-Brom-6-fluor-phenylimino)-imidazolidin, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
DE2806775A1 (de) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2806811A1 (de) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben
CA1138451A (en) * 1979-04-03 1982-12-28 Ikuo Ueda 2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same
HU192986B (en) 1984-05-23 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of imidasodiline derivatives
AU2007213887A1 (en) * 2006-01-27 2007-08-16 F. Hoffmann-La Roche Ag Use of 2-imidazoles for the treatment of CNS disorders
BRPI0806940A2 (pt) 2007-02-02 2014-05-06 Hoffmann La Roche 2-amino-oxazolinas como ligantes taar1 para distúrbios do snc
MX2009008465A (es) 2007-02-15 2009-08-20 Hoffmann La Roche Nuevas 2-aminooxazolinas como ligandos de taar1.
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
BR112018015389B1 (pt) 2016-03-17 2023-12-19 F. Hoffmann-La Roche Ag Derivado de 5-etil-4-metil-pirazol-3-carboxamida, seu processo de fabricação, preparação farmacêutica oral e uso

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE1670807A1 (de) * 1967-02-17 1971-03-11 Bayer Ag Verfahren zur Herstellung von cyclischen Guanidinen
DE1670918A1 (de) * 1967-09-07 1971-04-08 Bayer Ag Verfahren zur Herstellung von 2-Aryl-amino-substituierten stickstoffhaltigen Heterocyclen
BE787683A (fr) * 1971-08-20 1973-02-19 Boehringer Sohn Ingelheim 2-phenylimino-imidazolidines, leurs sels d'addition avec des acides et procedes pour les fabriquer

Also Published As

Publication number Publication date
DE2446758C3 (de) 1979-01-04
PH13653A (en) 1980-08-21
YU230281A (en) 1982-02-28
LU73472A1 (de) 1977-05-16
BE834051A (fr) 1976-03-30
IL48214A0 (en) 1975-11-25
IE42130B1 (en) 1980-06-04
BG25221A3 (en) 1978-08-10
ZA756185B (en) 1977-06-29
ES444901A1 (es) 1977-04-16
CS193524B2 (en) 1979-10-31
CH626352A5 (en) 1981-11-13
AT344159B (de) 1978-07-10
SE418497B (sv) 1981-06-09
FR2286649B1 (de) 1979-09-14
JPS6018653B2 (ja) 1985-05-11
SE7511028L (sv) 1976-04-02
FI752728A (de) 1976-04-02
SU575026A3 (ru) 1977-09-30
DE2446758A1 (de) 1976-04-22
AU8529875A (en) 1977-04-07
DD123602A5 (de) 1977-01-05
CA1056836A (en) 1979-06-19
NO143459C (no) 1981-02-18
ES444900A1 (es) 1977-04-16
DK441875A (da) 1976-04-02
DE2446758B2 (de) 1978-05-18
ES444898A1 (es) 1977-05-16
GB1515019A (en) 1978-06-21
BG25220A3 (en) 1978-08-10
NZ178810A (en) 1978-04-03
FR2286649A1 (fr) 1976-04-30
PL98984B1 (pl) 1978-06-30
HU178469B (en) 1982-05-28
FI61883C (fi) 1982-10-11
ES441385A1 (es) 1977-08-01
NO143459B (no) 1980-11-10
NL7511490A (nl) 1976-04-05
IL48214A (en) 1979-10-31
CH627453A5 (en) 1982-01-15
CH620682A5 (en) 1980-12-15
PL97003B1 (pl) 1978-01-31
CH627454A5 (en) 1982-01-15
IE42130L (en) 1976-04-01
NO753314L (de) 1976-04-02
JPS5159863A (en) 1976-05-25
FI61883B (fi) 1982-06-30
CH627452A5 (en) 1982-01-15

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee