NZ178810A - 2,6-disubstituted 2-phenylimino-imidazolidines, preparation and pharmaceutical compositions - Google Patents

2,6-disubstituted 2-phenylimino-imidazolidines, preparation and pharmaceutical compositions

Info

Publication number
NZ178810A
NZ178810A NZ178810A NZ17881075A NZ178810A NZ 178810 A NZ178810 A NZ 178810A NZ 178810 A NZ178810 A NZ 178810A NZ 17881075 A NZ17881075 A NZ 17881075A NZ 178810 A NZ178810 A NZ 178810A
Authority
NZ
New Zealand
Prior art keywords
imidazolidines
phenylimino
disubstituted
preparation
pharmaceutical compositions
Prior art date
Application number
NZ178810A
Other languages
English (en)
Inventor
W Kummer
H Stahle
H Koppe
W Hoefke
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of NZ178810A publication Critical patent/NZ178810A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • C07D233/50Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
NZ178810A 1974-10-01 1975-09-30 2,6-disubstituted 2-phenylimino-imidazolidines, preparation and pharmaceutical compositions NZ178810A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2446758A DE2446758C3 (de) 1974-10-01 1974-10-01 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie

Publications (1)

Publication Number Publication Date
NZ178810A true NZ178810A (en) 1978-04-03

Family

ID=5927202

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ178810A NZ178810A (en) 1974-10-01 1975-09-30 2,6-disubstituted 2-phenylimino-imidazolidines, preparation and pharmaceutical compositions

Country Status (27)

Country Link
JP (1) JPS6018653B2 (de)
AT (1) AT344159B (de)
BE (1) BE834051A (de)
BG (2) BG25220A3 (de)
CA (1) CA1056836A (de)
CH (5) CH620682A5 (de)
CS (1) CS193524B2 (de)
DD (1) DD123602A5 (de)
DE (1) DE2446758C3 (de)
DK (1) DK441875A (de)
ES (4) ES441385A1 (de)
FI (1) FI61883C (de)
FR (1) FR2286649A1 (de)
GB (1) GB1515019A (de)
HU (1) HU178469B (de)
IE (1) IE42130B1 (de)
IL (1) IL48214A (de)
LU (1) LU73472A1 (de)
NL (1) NL7511490A (de)
NO (1) NO143459C (de)
NZ (1) NZ178810A (de)
PH (1) PH13653A (de)
PL (2) PL98984B1 (de)
SE (1) SE418497B (de)
SU (1) SU575026A3 (de)
YU (1) YU230281A (de)
ZA (1) ZA756185B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2630060C2 (de) * 1976-07-03 1984-04-19 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-Brom-6-fluor-phenylimino)-imidazolidin, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
DE2806775A1 (de) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2806811A1 (de) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben
ZA801680B (en) * 1979-04-03 1981-03-25 Fujisawa Pharmaceutical Co 2-imidazoline derivatives,process for the preparation thereof and the pharmaceutical composition of the same
HU192986B (en) 1984-05-23 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of imidasodiline derivatives
EP1981498A2 (de) * 2006-01-27 2008-10-22 F. Hoffmann-la Roche AG Verwendung von 2-imidazolen zur behandlung von leiden des zentralen nervensystems
CA2675221C (en) 2007-02-02 2016-02-23 F. Hoffmann-La Roche Ag Novel 2-aminooxazolines as taar1 ligands
WO2008098857A1 (en) 2007-02-15 2008-08-21 F. Hoffmann-La Roche Ag 2-aminooxazolines as taar1 ligands
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
EP3757102A1 (de) 2016-03-17 2020-12-30 F. Hoffmann-La Roche AG 5-ethyl-4-methyl-pyrazole-3-carboxamid-derivat mit wirkung als taar agonist

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE1670807A1 (de) * 1967-02-17 1971-03-11 Bayer Ag Verfahren zur Herstellung von cyclischen Guanidinen
DE1670918A1 (de) * 1967-09-07 1971-04-08 Bayer Ag Verfahren zur Herstellung von 2-Aryl-amino-substituierten stickstoffhaltigen Heterocyclen
BE787683A (fr) * 1971-08-20 1973-02-19 Boehringer Sohn Ingelheim 2-phenylimino-imidazolidines, leurs sels d'addition avec des acides et procedes pour les fabriquer

Also Published As

Publication number Publication date
NO753314L (de) 1976-04-02
DK441875A (da) 1976-04-02
NO143459B (no) 1980-11-10
AU8529875A (en) 1977-04-07
JPS5159863A (en) 1976-05-25
NO143459C (no) 1981-02-18
YU230281A (en) 1982-02-28
DE2446758A1 (de) 1976-04-22
CH627453A5 (en) 1982-01-15
ES441385A1 (es) 1977-08-01
BG25221A3 (en) 1978-08-10
CH627452A5 (en) 1982-01-15
BG25220A3 (en) 1978-08-10
DD123602A5 (de) 1977-01-05
NL7511490A (nl) 1976-04-05
DE2446758C3 (de) 1979-01-04
SU575026A3 (ru) 1977-09-30
ES444901A1 (es) 1977-04-16
FI752728A (de) 1976-04-02
LU73472A1 (de) 1977-05-16
ES444900A1 (es) 1977-04-16
FI61883C (fi) 1982-10-11
FR2286649B1 (de) 1979-09-14
PL98984B1 (pl) 1978-06-30
GB1515019A (en) 1978-06-21
ZA756185B (en) 1977-06-29
CH620682A5 (en) 1980-12-15
CH626352A5 (en) 1981-11-13
FI61883B (fi) 1982-06-30
ATA722875A (de) 1977-11-15
IL48214A0 (en) 1975-11-25
CA1056836A (en) 1979-06-19
CS193524B2 (en) 1979-10-31
PH13653A (en) 1980-08-21
SE7511028L (sv) 1976-04-02
AT344159B (de) 1978-07-10
IL48214A (en) 1979-10-31
IE42130B1 (en) 1980-06-04
ES444898A1 (es) 1977-05-16
CH627454A5 (en) 1982-01-15
SE418497B (sv) 1981-06-09
IE42130L (en) 1976-04-01
DE2446758B2 (de) 1978-05-18
JPS6018653B2 (ja) 1985-05-11
FR2286649A1 (fr) 1976-04-30
PL97003B1 (pl) 1978-01-31
HU178469B (en) 1982-05-28
BE834051A (fr) 1976-03-30

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