FR2286649A1 - Nouvelles 2-phenylimino-imidazolidines, disubstituees en 2 et 6, leurs sels d'addition avec des acides, medicaments a base de ces nouveaux composes et procedes de fabrication - Google Patents

Nouvelles 2-phenylimino-imidazolidines, disubstituees en 2 et 6, leurs sels d'addition avec des acides, medicaments a base de ces nouveaux composes et procedes de fabrication

Info

Publication number
FR2286649A1
FR2286649A1 FR7530117A FR7530117A FR2286649A1 FR 2286649 A1 FR2286649 A1 FR 2286649A1 FR 7530117 A FR7530117 A FR 7530117A FR 7530117 A FR7530117 A FR 7530117A FR 2286649 A1 FR2286649 A1 FR 2286649A1
Authority
FR
France
Prior art keywords
new
imidazolidines
phenylimino
disubstituted
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7530117A
Other languages
English (en)
Other versions
FR2286649B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of FR2286649A1 publication Critical patent/FR2286649A1/fr
Application granted granted Critical
Publication of FR2286649B1 publication Critical patent/FR2286649B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR7530117A 1974-10-01 1975-10-01 Nouvelles 2-phenylimino-imidazolidines, disubstituees en 2 et 6, leurs sels d'addition avec des acides, medicaments a base de ces nouveaux composes et procedes de fabrication Granted FR2286649A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2446758A DE2446758C3 (de) 1974-10-01 1974-10-01 2-(2-Fluor-6-trifluormethylphenylimino)-imidazolidin, dessen Säureadditionssalze, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung bei der Bekämpfung der Hypertonie

Publications (2)

Publication Number Publication Date
FR2286649A1 true FR2286649A1 (fr) 1976-04-30
FR2286649B1 FR2286649B1 (fr) 1979-09-14

Family

ID=5927202

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7530117A Granted FR2286649A1 (fr) 1974-10-01 1975-10-01 Nouvelles 2-phenylimino-imidazolidines, disubstituees en 2 et 6, leurs sels d'addition avec des acides, medicaments a base de ces nouveaux composes et procedes de fabrication

Country Status (27)

Country Link
JP (1) JPS6018653B2 (fr)
AT (1) AT344159B (fr)
BE (1) BE834051A (fr)
BG (2) BG25220A3 (fr)
CA (1) CA1056836A (fr)
CH (5) CH620682A5 (fr)
CS (1) CS193524B2 (fr)
DD (1) DD123602A5 (fr)
DE (1) DE2446758C3 (fr)
DK (1) DK441875A (fr)
ES (4) ES441385A1 (fr)
FI (1) FI61883C (fr)
FR (1) FR2286649A1 (fr)
GB (1) GB1515019A (fr)
HU (1) HU178469B (fr)
IE (1) IE42130B1 (fr)
IL (1) IL48214A (fr)
LU (1) LU73472A1 (fr)
NL (1) NL7511490A (fr)
NO (1) NO143459C (fr)
NZ (1) NZ178810A (fr)
PH (1) PH13653A (fr)
PL (2) PL97003B1 (fr)
SE (1) SE418497B (fr)
SU (1) SU575026A3 (fr)
YU (1) YU230281A (fr)
ZA (1) ZA756185B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2417502A1 (fr) * 1978-02-17 1979-09-14 Boehringer Sohn Ingelheim Nouvelles 2-phenylimino-imidazolidines substituees, leurs sels d'addition avec des acides, medicaments les renfermant et procedes pour leur preparation

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2630060C2 (de) * 1976-07-03 1984-04-19 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-Brom-6-fluor-phenylimino)-imidazolidin, dessen Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
DE2806811A1 (de) * 1978-02-17 1979-08-23 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben
ZA801680B (en) * 1979-04-03 1981-03-25 Fujisawa Pharmaceutical Co 2-imidazoline derivatives,process for the preparation thereof and the pharmaceutical composition of the same
HU192986B (en) 1984-05-23 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of imidasodiline derivatives
CA2637292A1 (fr) * 2006-01-27 2007-08-16 F. Hoffmann-La Roche Ag Utilisation de 2-imidazoles pour le traitement de troubles du systeme nerveux central
JP5248528B2 (ja) 2007-02-02 2013-07-31 エフ．ホフマン−ラ ロシュ アーゲー Ｃｎｓ疾患用のｔａａｒ１リガンドとしての新規２−アミノオキサゾリン
CA2676944C (fr) 2007-02-15 2016-01-19 F. Hoffmann-La Roche Ag 2-aminooxazolines comme ligands de taar1
US8242153B2 (en) 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
US8354441B2 (en) 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
SG11201807516UA (en) 2016-03-17 2018-09-27 Hoffmann La Roche 5-ethyl-4-methyl-pyrazole-3-carboxamide derivative having activity as agonist of taar

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE1670807A1 (de) * 1967-02-17 1971-03-11 Bayer Ag Verfahren zur Herstellung von cyclischen Guanidinen
DE1670918A1 (de) * 1967-09-07 1971-04-08 Bayer Ag Verfahren zur Herstellung von 2-Aryl-amino-substituierten stickstoffhaltigen Heterocyclen
FR2150808A1 (fr) * 1971-08-20 1973-04-13 Boehringer Sohn Ingelheim

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
DE1670807A1 (de) * 1967-02-17 1971-03-11 Bayer Ag Verfahren zur Herstellung von cyclischen Guanidinen
DE1670918A1 (de) * 1967-09-07 1971-04-08 Bayer Ag Verfahren zur Herstellung von 2-Aryl-amino-substituierten stickstoffhaltigen Heterocyclen
FR2150808A1 (fr) * 1971-08-20 1973-04-13 Boehringer Sohn Ingelheim

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2417502A1 (fr) * 1978-02-17 1979-09-14 Boehringer Sohn Ingelheim Nouvelles 2-phenylimino-imidazolidines substituees, leurs sels d'addition avec des acides, medicaments les renfermant et procedes pour leur preparation

Also Published As

Publication number Publication date
DD123602A5 (fr) 1977-01-05
FR2286649B1 (fr) 1979-09-14
IE42130L (en) 1976-04-01
ES441385A1 (es) 1977-08-01
CH627454A5 (en) 1982-01-15
BE834051A (fr) 1976-03-30
ES444898A1 (es) 1977-05-16
FI61883C (fi) 1982-10-11
FI752728A (fr) 1976-04-02
JPS5159863A (en) 1976-05-25
DE2446758C3 (de) 1979-01-04
NZ178810A (en) 1978-04-03
CS193524B2 (en) 1979-10-31
DE2446758A1 (de) 1976-04-22
PL97003B1 (pl) 1978-01-31
ATA722875A (de) 1977-11-15
CH627453A5 (en) 1982-01-15
NO143459C (no) 1981-02-18
CH627452A5 (en) 1982-01-15
AU8529875A (en) 1977-04-07
BG25221A3 (en) 1978-08-10
IL48214A0 (en) 1975-11-25
SE418497B (sv) 1981-06-09
ZA756185B (en) 1977-06-29
JPS6018653B2 (ja) 1985-05-11
PL98984B1 (pl) 1978-06-30
BG25220A3 (en) 1978-08-10
FI61883B (fi) 1982-06-30
YU230281A (en) 1982-02-28
NO753314L (fr) 1976-04-02
CH626352A5 (en) 1981-11-13
ES444900A1 (es) 1977-04-16
IE42130B1 (en) 1980-06-04
CA1056836A (fr) 1979-06-19
DE2446758B2 (de) 1978-05-18
ES444901A1 (es) 1977-04-16
GB1515019A (en) 1978-06-21
SU575026A3 (ru) 1977-09-30
PH13653A (en) 1980-08-21
HU178469B (en) 1982-05-28
DK441875A (da) 1976-04-02
SE7511028L (sv) 1976-04-02
NO143459B (no) 1980-11-10
IL48214A (en) 1979-10-31
NL7511490A (nl) 1976-04-05
AT344159B (de) 1978-07-10
LU73472A1 (fr) 1977-05-16
CH620682A5 (en) 1980-12-15

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ST Notification of lapse