IE41928B1 - Esters of 1-acylpiperazine-4-carboxylic acids - Google Patents

Esters of 1-acylpiperazine-4-carboxylic acids

Info

Publication number
IE41928B1
IE41928B1 IE2414/75A IE241475A IE41928B1 IE 41928 B1 IE41928 B1 IE 41928B1 IE 2414/75 A IE2414/75 A IE 2414/75A IE 241475 A IE241475 A IE 241475A IE 41928 B1 IE41928 B1 IE 41928B1
Authority
IE
Ireland
Prior art keywords
naphthyridin
carbon atoms
chloro
radical
general formula
Prior art date
Application number
IE2414/75A
Other languages
English (en)
Other versions
IE41928L (en
Original Assignee
Rhone Poulenc Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7436963A external-priority patent/FR2313060A1/fr
Priority claimed from FR7527161A external-priority patent/FR2322601A1/fr
Priority claimed from FR7527160A external-priority patent/FR2322600A1/fr
Priority claimed from FR7527162A external-priority patent/FR2322602A1/fr
Application filed by Rhone Poulenc Ind filed Critical Rhone Poulenc Ind
Publication of IE41928L publication Critical patent/IE41928L/xx
Publication of IE41928B1 publication Critical patent/IE41928B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
IE2414/75A 1974-11-07 1975-11-05 Esters of 1-acylpiperazine-4-carboxylic acids IE41928B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR7436963A FR2313060A1 (fr) 1974-11-07 1974-11-07 Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR7527161A FR2322601A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR7527160A FR2322600A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de la pyrrolo (3,4-b) pyrazine, leur preparation et les compositions qui les contiennent
FR7527162A FR2322602A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de l'oxathiinno- et du dithiinnopyrrole, leur preparation et les compositions qui les contiennent

Publications (2)

Publication Number Publication Date
IE41928L IE41928L (en) 1976-05-07
IE41928B1 true IE41928B1 (en) 1980-04-23

Family

ID=27446274

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2414/75A IE41928B1 (en) 1974-11-07 1975-11-05 Esters of 1-acylpiperazine-4-carboxylic acids

Country Status (27)

Country Link
US (1) US4220646A (en, 2012)
JP (2) JPS5422996B2 (en, 2012)
AR (2) AR208414A1 (en, 2012)
AT (2) AT343123B (en, 2012)
AU (1) AU503200B2 (en, 2012)
BE (1) BE835325A (en, 2012)
CA (1) CA1057755A (en, 2012)
CH (1) CH609057A5 (en, 2012)
CS (2) CS231957B2 (en, 2012)
CY (1) CY1045A (en, 2012)
DD (1) DD122684A5 (en, 2012)
DE (1) DE2550111C2 (en, 2012)
DK (1) DK141098B (en, 2012)
FI (1) FI60707C (en, 2012)
GB (1) GB1468497A (en, 2012)
HK (1) HK19380A (en, 2012)
HU (1) HU173108B (en, 2012)
IE (1) IE41928B1 (en, 2012)
IL (1) IL48423A (en, 2012)
LU (1) LU73738A1 (en, 2012)
NL (1) NL177405C (en, 2012)
NO (1) NO143576C (en, 2012)
OA (1) OA05162A (en, 2012)
PL (1) PL101248B1 (en, 2012)
SE (1) SE407063B (en, 2012)
SU (2) SU673173A3 (en, 2012)
YU (2) YU39583B (en, 2012)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2371198A2 (fr) * 1976-11-22 1978-06-16 Rhone Poulenc Ind Nouveaux derives du dithiepinno (1,4)(2,3-c) pyrrole, leur preparation et les compositions qui les contiennent
US4533751A (en) * 1981-10-09 1985-08-06 Scm Corporation Preparation of 1,3-dienamines from myrcene and substituted myrcene
FR2525606A1 (fr) * 1982-04-22 1983-10-28 Rhone Poulenc Sante Nouveaux derives du dithiino (1,4) (2,3-c) pyrrole, leur preparation et les medicaments qui les contiennent
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607506B1 (fr) * 1986-12-02 1989-01-06 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2671800B1 (fr) 1991-01-17 1993-03-12 Rhone Poulenc Rorer Sa Derive de la 5h-pyrrolo[3,4-b]pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent.
US5786357A (en) 1991-12-02 1998-07-28 Sepracor Inc. Methods and compositions for treating sleep disorders, convulsive seizures and other disorders using optically pure (+) zopiclone
HU214331B (hu) * 1992-06-17 1998-03-02 Gyógyszerkutató Intézet Kft. Eljárás piperazin- és homopiperazinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
TW279864B (en, 2012) * 1993-02-19 1996-07-01 Janssen Pharmaceutica Nv
US5922820A (en) * 1993-06-04 1999-07-13 Henkel Corporation Polymerizable compounds
JPH08511022A (ja) * 1993-06-04 1996-11-19 ヘンケル コーポレーション 重合可能な化合物
US5565567A (en) * 1993-06-04 1996-10-15 Henkel Corporation. Polymerizable N,N'-substituted piperazine acrylamide compounds
MX9702125A (es) * 1994-09-23 1998-04-30 Arris Pharm Corp Composiciones y metodos para tratar condiciones inflamatorias mediadas por mastocitos.
US5663357A (en) 1995-11-22 1997-09-02 Allergan Substituted heteroarylamides having retinoid-like biological activity
US5756742A (en) * 1995-12-22 1998-05-26 Henkel Corporation Polymerizable compounds
US6339086B1 (en) * 1999-05-14 2002-01-15 Swpracor, Inc. Methods of making and using N-desmethylzopiclone
EP1396493A4 (en) * 2001-04-26 2005-08-03 Ajinomoto Kk HETEROCYCLIC COMPOUNDS
DE60303363T2 (de) * 2002-03-29 2006-10-12 Indevus Pharmaceuticals, Inc., Lexington Verfahren zur herstellung von 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxo-hexyl)-1-isoindolinon
WO2004037212A2 (en) * 2002-10-24 2004-05-06 Sepracor, Inc. Compositions comprising zopiclone derivatives and methods of making and using the same
CN1326856C (zh) * 2002-11-22 2007-07-18 麦克公司 制备磷酸二酯酶－4抑制剂的方法
US6909002B2 (en) * 2002-11-22 2005-06-21 Merck & Co., Inc. Method of preparing inhibitors of phosphodiesterase-4
AR042194A1 (es) * 2002-11-22 2005-06-15 Merck & Co Inc Metodo para preparar inhibidores de fosfodiesterasa - 4
WO2005060968A1 (en) 2003-12-11 2005-07-07 Sepracor Inc. Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
US20050232983A1 (en) * 2004-04-14 2005-10-20 Indevus Pharmaceuticals, Inc. Transdermal patch
AU2006265008A1 (en) * 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and O-desmethylvenlafaxine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
CA2957667A1 (en) 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
US7985756B2 (en) 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20080305171A1 (en) * 2007-06-07 2008-12-11 Kristin Anne Arnold Pyrrolopyrazine, formulations, methods of manufacture, and methods of use there
CN100569775C (zh) * 2007-12-19 2009-12-16 齐鲁天和惠世制药有限公司 佐匹克隆的晶型转换的方法
AU2010208240A1 (en) 2009-01-30 2011-09-22 Sunovion Pharmaceuticals Inc Coated tablets of 6-(5-chloro-2-pyridyl) -5-[ (4-methyl-1-piperazinyl) carbonyloxy]-7-oxo-6, 7-dihydro-5H-pyrrol o [3,4-b] pyrazine and methods for measuring effectiveness of coating
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
KR102565511B1 (ko) * 2017-05-25 2023-08-10 신에쓰 가가꾸 고교 가부시끼가이샤 플루오로폴리에테르기 함유 폴리머 변성 유기 규소 화합물, 표면처리제 및 물품
CN108129476A (zh) * 2017-11-27 2018-06-08 华中农业大学 一种杂环内酰胺衍生物及其用于作物病原菌杀菌剂的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1312427A (fr) * 1961-04-12 1962-12-21 Science Union Et Compagnie Soc Nouveaux dérivés de la pipérazine et leurs préparations
FR2101081B1 (en, 2012) * 1970-08-19 1974-01-11 Rhone Poulenc Sa
BE790408A (fr) * 1971-10-22 1973-04-20 Rhone Poulenc Sa Nouveaux derives de la pyrrolo (3,4-b) pyridine, leur preparation et les compositions medicinales qui les
OA04285A (fr) * 1972-01-07 1979-12-31 Rhone Poulenc Sa Nouveaux dérivés de la pyrrolo (3,4-b) pyrazine et leur préparation.
BE793851A (fr) * 1972-01-10 1973-07-10 Rhone Poulenc Sa Nouveaux derives de l'isoindoline, leur preparation et les compositions medicinales qui les contiennent
AR207555A1 (es) * 1972-12-04 1976-10-15 Procedimiento para preparar aril-6-piperazinocarboniloxi-5 oxo-7 tetrahidro-2,3,6,7 ditiino(1,4)(2,3-c)pirroles
OA04700A (fr) * 1973-05-15 1980-07-31 Rhone Poulenc Sa Nouveaux dérivés de la naphtyridine et leur procédé de préparation.

Also Published As

Publication number Publication date
IE41928L (en) 1976-05-07
YU192182A (en) 1983-01-21
ATA401977A (de) 1977-10-15
CS751075A2 (en) 1984-01-16
PL101248B1 (pl) 1978-12-30
AT343666B (de) 1978-06-12
US4220646A (en) 1980-09-02
FI60707B (fi) 1981-11-30
LU73738A1 (en, 2012) 1976-09-06
SU673173A3 (ru) 1979-07-05
CS231958B2 (en) 1985-01-16
IL48423A0 (en) 1976-01-30
DE2550111A1 (de) 1976-05-13
YU281575A (en) 1983-01-21
FI753127A7 (en, 2012) 1976-05-08
AR208800A1 (es) 1977-02-28
SE407063B (sv) 1979-03-12
CS598377A2 (en) 1984-01-16
HU173108B (hu) 1979-02-28
AR208414A1 (es) 1976-12-27
JPS5422996B2 (en, 2012) 1979-08-10
CA1057755A (fr) 1979-07-03
HK19380A (en) 1980-04-18
JPS5498790A (en) 1979-08-03
NO143576B (no) 1980-12-01
ATA848675A (de) 1977-09-15
AU8633175A (en) 1977-05-12
JPS5170776A (en, 2012) 1976-06-18
CS231957B2 (en) 1985-01-16
AT343123B (de) 1978-05-10
SE7512477L (sv) 1976-05-10
DD122684A5 (en, 2012) 1976-10-20
IL48423A (en) 1979-03-12
YU40087B (en) 1985-06-30
NO753713L (en, 2012) 1976-05-10
OA05162A (fr) 1981-01-31
DK499275A (en, 2012) 1976-05-08
GB1468497A (en) 1977-03-30
FI60707C (fi) 1982-03-10
AU503200B2 (en) 1979-08-30
DE2550111C2 (de) 1983-09-15
DK141098B (da) 1980-01-14
JPS558508B2 (en, 2012) 1980-03-04
CY1045A (en) 1980-08-01
CH609057A5 (en, 2012) 1979-02-15
NO143576C (no) 1981-03-11
DK141098C (en, 2012) 1980-07-07
SU604496A3 (ru) 1978-04-25
NL7512732A (nl) 1976-05-11
BE835325A (fr) 1976-05-06
NL177405B (nl) 1985-04-16
NL177405C (nl) 1985-09-16
YU39583B (en) 1985-03-20

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