ID26697A - Pemurnian neurotrofin - Google Patents
Pemurnian neurotrofinInfo
- Publication number
- ID26697A ID26697A IDW990339D ID990339D ID26697A ID 26697 A ID26697 A ID 26697A ID W990339 D IDW990339 D ID W990339D ID 990339 D ID990339 D ID 990339D ID 26697 A ID26697 A ID 26697A
- Authority
- ID
- Indonesia
- Prior art keywords
- neurotrophins
- purification
- neurotrofin
- including mature
- mature ngf
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/48—Nerve growth factor [NGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3083896P | 1996-11-15 | 1996-11-15 | |
US4785597P | 1997-05-29 | 1997-05-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ID26697A true ID26697A (id) | 2001-02-01 |
Family
ID=26706516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW990339D ID26697A (id) | 1996-11-15 | 1997-11-14 | Pemurnian neurotrofin |
Country Status (21)
Country | Link |
---|---|
US (5) | US6005081A (zh) |
EP (1) | EP0942930B1 (zh) |
JP (3) | JP4671372B2 (zh) |
KR (1) | KR100554332B1 (zh) |
CN (1) | CN1268639C (zh) |
AT (1) | ATE371670T1 (zh) |
AU (1) | AU729459B2 (zh) |
BR (1) | BR9713055A (zh) |
CA (1) | CA2268747A1 (zh) |
CZ (1) | CZ300296B6 (zh) |
DE (1) | DE69738074T2 (zh) |
EA (1) | EA002349B1 (zh) |
ES (1) | ES2293662T3 (zh) |
HU (1) | HU222666B1 (zh) |
ID (1) | ID26697A (zh) |
IL (2) | IL129851A0 (zh) |
NO (1) | NO327149B1 (zh) |
NZ (1) | NZ335207A (zh) |
PL (1) | PL191400B1 (zh) |
TR (1) | TR199901734T2 (zh) |
WO (1) | WO1998021234A2 (zh) |
Families Citing this family (57)
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WO1998021234A2 (en) * | 1996-11-15 | 1998-05-22 | Genentech, Inc. | Purification of neurotrophins |
JP2001524670A (ja) * | 1997-11-20 | 2001-12-04 | イーエスエー・インコーポレーテッド | 電気化学的分析システム |
CN103641885A (zh) * | 1998-05-06 | 2014-03-19 | 基因技术股份有限公司 | 用离子交换层析纯化蛋白质 |
DK1681299T3 (da) | 2000-03-27 | 2010-02-01 | Genetics Inst Llc | Fremgangsmåde til rensning af højt anioniske proteiner |
DE60231016D1 (de) * | 2001-06-05 | 2009-03-12 | Genetics Inst Llc | Verfahren zur Reinigung stark anionischer Proteine |
EP1456233A4 (en) * | 2001-06-15 | 2006-06-21 | Queensland Bioproc Technology | ORMEAU HEMOCYANINE AND METHOD FOR PURIFICATION THEREOF |
EP1545608A4 (en) | 2002-06-28 | 2006-09-13 | Centocor Inc | CH1-DELETED MAMMED MUICETIC BODIES, COMPOSITIONS, METHODS AND APPLICATIONS |
US7998705B2 (en) * | 2002-08-06 | 2011-08-16 | FUJIFILM Diosynth Biotechnologies U.S.A., Inc | Increased dynamic binding capacity in ion exchange chromatography by addition of polyethylene glycol |
AU2003902066A0 (en) * | 2003-05-01 | 2003-05-15 | Norika Holdings | Extraction process for a pharmaceutical product |
CA2487673C (en) * | 2003-12-02 | 2010-11-02 | F. Hoffmann-La Roche Ag | Improved method for the recombinant production and purification of protein kinases |
EP1538201A1 (en) * | 2003-12-02 | 2005-06-08 | F.Hoffmann-La Roche Ag | Method for the recombinant production and purification of protein kinases |
CA2556923A1 (en) * | 2004-02-20 | 2005-09-09 | Rinat Neuroscience Corp. | Methods of treating obesity or diabetes using nt-4/5 |
PT2100904E (pt) * | 2004-04-23 | 2010-09-24 | Conjuchem Biotechnologies Inc | Fase sólida para utilização num método para a purificação de conjugados de albumina |
EP1888117A1 (en) * | 2005-05-25 | 2008-02-20 | Novo Nordisk A/S | Stabilized polypeptide formulations |
CN101180081B (zh) | 2005-05-25 | 2015-08-26 | 诺沃-诺迪斯克有限公司 | 稳定的多肽制剂 |
WO2007022799A1 (en) | 2005-08-26 | 2007-03-01 | Ares Trading S.A. | Process for the preparation of glycosylated interferon beta |
EP1960419B1 (en) * | 2005-12-09 | 2016-03-16 | Ares Trading S.A. | Method for purifying fsh or a fsh mutant |
CN100419422C (zh) * | 2005-12-12 | 2008-09-17 | 北京三诺佳邑生物技术有限责任公司 | 测定神经生长因子含量的方法 |
AR058568A1 (es) | 2005-12-20 | 2008-02-13 | Bristol Myers Squibb Co | Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo |
EP1969007B1 (en) | 2005-12-20 | 2013-08-28 | Bristol-Myers Squibb Company | Compositions and methods for producing a composition |
AU2007210862A1 (en) | 2006-02-02 | 2007-08-09 | Rinat Neuroscience Corp. | Methods for treating unwanted weight loss or eating disorders by administering a trkB agonist |
JP2009525319A (ja) * | 2006-02-02 | 2009-07-09 | ライナット ニューロサイエンス コーポレイション | trkBアンタゴニストを投与することにより肥満を治療する方法 |
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SI2215117T2 (en) | 2007-10-30 | 2018-04-30 | Genentech, Inc. | Purification of the antibody by cation exchange chromatography |
US8447409B2 (en) * | 2008-10-15 | 2013-05-21 | Cochlear Limited | Electroneural interface for a medical implant |
US20120269815A1 (en) * | 2008-12-23 | 2012-10-25 | Regents Of The University Of Minnesota | Neurotrophins and uses thereof |
JP5695384B2 (ja) | 2009-10-05 | 2015-04-01 | 花王株式会社 | 毛髪形状感受性遺伝子 |
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EP2587265B1 (en) * | 2010-06-25 | 2016-05-04 | Nippon Zoki Pharmaceutical Co., Ltd. | Method for determination or evaluation of test substance |
CN102898514B (zh) * | 2011-07-28 | 2015-04-29 | 中国人民解放军军事医学科学院生物工程研究所 | 重组人神经生长因子缺失突变体及其制备方法和用途 |
EP2594295A1 (en) | 2011-11-16 | 2013-05-22 | Servicio Andaluz De Salud | Nerve implants based on a compacted biomaterial containing cells |
US9266370B2 (en) | 2012-10-10 | 2016-02-23 | Apdn (B.V.I) Inc. | DNA marking of previously undistinguished items for traceability |
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CN103880943A (zh) * | 2014-01-20 | 2014-06-25 | 厦门北大之路生物工程有限公司 | 一种rhNGF成熟肽的制备方法 |
US10745825B2 (en) | 2014-03-18 | 2020-08-18 | Apdn (B.V.I.) Inc. | Encrypted optical markers for security applications |
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CN104195160A (zh) * | 2014-08-08 | 2014-12-10 | 厦门北大之路生物工程有限公司 | 一种以Pro-BDNF的形式制备人脑源性神经营养因子的方法 |
US10760182B2 (en) | 2014-12-16 | 2020-09-01 | Apdn (B.V.I.) Inc. | Method and device for marking fibrous materials |
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CN109070130B (zh) | 2016-04-11 | 2022-03-22 | 亚普蒂恩(B V I)公司 | 用于标记纤维素产品的方法 |
CN106478801A (zh) * | 2016-10-10 | 2017-03-08 | 未名生物医药有限公司 | 一种从哺乳动物细胞培养物中分离重组人神经生长因子的方法 |
US10995371B2 (en) | 2016-10-13 | 2021-05-04 | Apdn (B.V.I.) Inc. | Composition and method of DNA marking elastomeric material |
US10920274B2 (en) | 2017-02-21 | 2021-02-16 | Apdn (B.V.I.) Inc. | Nucleic acid coated submicron particles for authentication |
GB201705955D0 (en) * | 2017-04-13 | 2017-05-31 | Cell Guidance Systems Ltd | Delivery method |
CN107973848B (zh) * | 2017-12-28 | 2020-10-16 | 未名生物医药有限公司 | 一种从混合物中分离天然序列神经生长因子的方法 |
CN108467429A (zh) * | 2018-03-26 | 2018-08-31 | 江苏中新医药有限公司 | 疏水层析动态清除重组人神经生长因子前体的方法 |
CN108239146A (zh) * | 2018-03-26 | 2018-07-03 | 江苏中新医药有限公司 | 一种高纯度rhNGF的制备方法 |
CN108467428A (zh) * | 2018-03-26 | 2018-08-31 | 江苏中新医药有限公司 | 一种清除rhNGF中N端截短及异常变异体的方法 |
EP3784691A1 (en) * | 2018-04-27 | 2021-03-03 | Chiesi Farmaceutici S.p.A. | Production of nerve growth factor (ngf) and of muteins thereof |
CN114252519B (zh) * | 2020-09-23 | 2023-11-24 | 舒泰神(北京)生物制药股份有限公司 | 一种测定神经生长因子纯度的方法 |
CN114380901A (zh) * | 2021-12-31 | 2022-04-22 | 华东理工大学 | 蛋白纳米粒子的制备方法、所得蛋白纳米粒子及其应用 |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4407744A (en) * | 1977-11-23 | 1983-10-04 | Young David M | Process for obtaining nerve growth factor |
US4565785A (en) * | 1978-06-08 | 1986-01-21 | The President And Fellows Of Harvard College | Recombinant DNA molecule |
US4673641A (en) * | 1982-12-16 | 1987-06-16 | Molecular Genetics Research And Development Limited Partnership | Co-aggregate purification of proteins |
DK161152C (da) * | 1983-03-03 | 1991-11-11 | Genentech Inc | Polypeptid med egenskaber som human beta-nervevaekstfaktor og fremgangsmaade til fremstilling deraf, dna-isolat omfattende en sekvens som koder for polypeptidet, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farmaceutisk praeparat indeholdende polypeptidet og fremg. der omfatter anvendelsen af polypeptidet til fremst. af et farmaceutisk praeparat |
US5169762A (en) * | 1983-03-03 | 1992-12-08 | Genentech, Inc. | Human nerve growth factor by recombinant technology |
US4710473A (en) * | 1983-08-10 | 1987-12-01 | Amgen, Inc. | DNA plasmids |
US4738921A (en) * | 1984-09-27 | 1988-04-19 | Eli Lilly And Company | Derivative of the tryptophan operon for expression of fused gene products |
US4795706A (en) * | 1985-01-31 | 1989-01-03 | Eli Lilly And Company | Novel expression control sequences |
IT1219874B (it) * | 1988-03-18 | 1990-05-24 | Fidia Farmaceutici | Utilizzazione del fattore di crescita nervoso umano e sue composizioni farmaceutiche |
US5082774A (en) * | 1988-08-30 | 1992-01-21 | The General Hospital Corporation | Recombinant human nerve growth factor |
US5272063A (en) * | 1988-11-22 | 1993-12-21 | Syntex (U.S.A.) Inc. | Process of making human nerve growth factor |
CA2005600A1 (en) * | 1988-12-20 | 1990-06-20 | Cal-Henrik Heldin | Endothelial cell growth factor |
DK0414151T3 (da) * | 1989-08-21 | 1995-05-22 | Takeda Chemical Industries Ltd | Humane nervevæskstfaktorproteiner og fremstilling deraf |
JPH04128300A (ja) * | 1989-08-21 | 1992-04-28 | Takeda Chem Ind Ltd | ヒト神経成長因子蛋白質およびその製造法 |
US5180820A (en) * | 1989-08-30 | 1993-01-19 | Barde Yves Alain | Brain-derived neurotrophic factor |
US5229500A (en) * | 1989-08-30 | 1993-07-20 | Regeneron Pharmaceuticals, Inc. | Brain derived neurotrophic factor |
US5606031A (en) * | 1990-04-06 | 1997-02-25 | Lile; Jack | Production and purification of biologically active recombinant neurotrophic protein in bacteria |
US5235043A (en) * | 1990-04-06 | 1993-08-10 | Synergen, Inc. | Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins |
US5169764A (en) * | 1990-08-08 | 1992-12-08 | Regeneron Pharmaceuticals, Inc. | Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras |
US5702906A (en) * | 1990-09-25 | 1997-12-30 | Genentech, Inc. | Antibodies to neurotrophic factor-4 (NT-4) |
US5364769A (en) * | 1990-09-25 | 1994-11-15 | Genentech, Inc. | Nucleic acid encoding neurotrophic factor four (NT-4), vectors, host cells and methods of production |
ATE140966T1 (de) * | 1990-09-25 | 1996-08-15 | Genentech Inc | Neuer neurotropischer faktor |
DK0499993T3 (da) * | 1991-02-18 | 1997-12-01 | Takeda Chemical Industries Ltd | Fremgangsmåde til fremstilling af human nervevækstfaktor-2 |
NZ243084A (en) * | 1991-06-12 | 1995-08-28 | Regeneron Pharma | Production and recovery of recombinant neurotrophins, genes for a modified lamb signal sequence, fusion genes and plasmids |
US5389529A (en) * | 1991-06-12 | 1995-02-14 | Regeneron Pharmaceuticals, Inc. | Modified lamβ signal sequence and processes for producing recombinant neurotrophins |
DE4133707A1 (de) * | 1991-10-11 | 1993-04-15 | Behringwerke Ag | Verfahren zur reinigung von streptolysin o, intaktes streptolysin o erhaeltlich nach diesem verfahren und seine verwendung |
JPH05211887A (ja) * | 1992-01-31 | 1993-08-24 | Hitachi Ltd | 神経成長因子の生産方法 |
US5349055A (en) * | 1992-03-06 | 1994-09-20 | Persson Hakan B | Nerve growth factor having altered receptor binding specificities |
US5488099A (en) * | 1992-03-06 | 1996-01-30 | Persson, Deceased; Hakan B. | Multifunctional chimeric neurotrophic factors |
US5451660A (en) * | 1993-12-13 | 1995-09-19 | Genentech, Inc. | Method for purifying polypeptides |
US5728803A (en) * | 1994-06-03 | 1998-03-17 | Genentech, Inc. | Pantropic neurotrophic factors |
US5798448A (en) * | 1994-10-27 | 1998-08-25 | Genentech, Inc. | AL-1 neurotrophic factor antibodies |
US5733875A (en) * | 1994-11-15 | 1998-03-31 | Amgen Inc. | Methods of using GDNF as a neuroprotective agent |
US5650496A (en) * | 1995-04-14 | 1997-07-22 | Cephalon, Inc. | IGF-I purification process |
IL118201A (en) * | 1995-05-11 | 2004-12-15 | Roche Diagnostics Gmbh | Preparation comprising a protein with human erythropoietin activity which is free of serum and non-recombinant mammalian protein and process for the preparation thereof |
US5739307A (en) * | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
WO1998021234A2 (en) * | 1996-11-15 | 1998-05-22 | Genentech, Inc. | Purification of neurotrophins |
-
1997
- 1997-11-14 WO PCT/US1997/021068 patent/WO1998021234A2/en active IP Right Grant
- 1997-11-14 PL PL333460A patent/PL191400B1/pl not_active IP Right Cessation
- 1997-11-14 DE DE69738074T patent/DE69738074T2/de not_active Expired - Lifetime
- 1997-11-14 EP EP97948362A patent/EP0942930B1/en not_active Expired - Lifetime
- 1997-11-14 NZ NZ335207A patent/NZ335207A/xx not_active IP Right Cessation
- 1997-11-14 ES ES97948362T patent/ES2293662T3/es not_active Expired - Lifetime
- 1997-11-14 CA CA002268747A patent/CA2268747A1/en not_active Abandoned
- 1997-11-14 ID IDW990339D patent/ID26697A/id unknown
- 1997-11-14 IL IL12985197A patent/IL129851A0/xx active IP Right Grant
- 1997-11-14 AT AT97948362T patent/ATE371670T1/de active
- 1997-11-14 TR TR1999/01734T patent/TR199901734T2/xx unknown
- 1997-11-14 BR BR9713055-9A patent/BR9713055A/pt not_active Application Discontinuation
- 1997-11-14 US US08/970,865 patent/US6005081A/en not_active Expired - Lifetime
- 1997-11-14 KR KR1019997004281A patent/KR100554332B1/ko not_active IP Right Cessation
- 1997-11-14 HU HU9903947A patent/HU222666B1/hu not_active IP Right Cessation
- 1997-11-14 EA EA199900436A patent/EA002349B1/ru not_active IP Right Cessation
- 1997-11-14 CZ CZ0166699A patent/CZ300296B6/cs not_active IP Right Cessation
- 1997-11-14 AU AU54448/98A patent/AU729459B2/en not_active Ceased
- 1997-11-14 JP JP52291398A patent/JP4671372B2/ja not_active Expired - Fee Related
- 1997-11-14 CN CNB971996822A patent/CN1268639C/zh not_active Expired - Fee Related
-
1999
- 1999-05-09 IL IL129851A patent/IL129851A/en not_active IP Right Cessation
- 1999-05-14 NO NO19992353A patent/NO327149B1/no not_active IP Right Cessation
- 1999-07-29 US US09/363,573 patent/US6184360B1/en not_active Expired - Lifetime
-
2000
- 2000-09-29 US US09/675,503 patent/US6423831B1/en not_active Expired - Fee Related
-
2002
- 2002-02-08 US US10/072,681 patent/US6812330B2/en not_active Expired - Fee Related
-
2004
- 2004-02-18 US US10/782,261 patent/US6953844B2/en not_active Expired - Fee Related
-
2007
- 2007-06-26 JP JP2007168104A patent/JP4881234B2/ja not_active Expired - Fee Related
-
2008
- 2008-08-13 JP JP2008208434A patent/JP2009040786A/ja not_active Withdrawn
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