HUS1900020I1 - CGRP ellenanyagok - Google Patents

CGRP ellenanyagok

Info

Publication number
HUS1900020I1
HUS1900020I1 HUS1900020C HUS1900020C HUS1900020I1 HU S1900020 I1 HUS1900020 I1 HU S1900020I1 HU S1900020 C HUS1900020 C HU S1900020C HU S1900020 C HUS1900020 C HU S1900020C HU S1900020 I1 HUS1900020 I1 HU S1900020I1
Authority
HU
Hungary
Prior art keywords
cgrp antibodies
cgrp
antibodies
Prior art date
Application number
HUS1900020C
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HUS1900020I1 publication Critical patent/HUS1900020I1/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57527Calcitonin gene related peptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57545Neuropeptide Y
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57563Vasoactive intestinal peptide [VIP]; Related peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
HUS1900020C 2010-06-10 2019-04-02 CGRP ellenanyagok HUS1900020I1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35332310P 2010-06-10 2010-06-10
EP11792989.3A EP2579894B1 (en) 2010-06-10 2011-06-07 Cgrp antibodies

Publications (1)

Publication Number Publication Date
HUS1900020I1 true HUS1900020I1 (hu) 2019-05-28

Family

ID=45096388

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE11792989A HUE038135T2 (hu) 2010-06-10 2011-06-07 CGRP ellenanyagok
HUS1900020C HUS1900020I1 (hu) 2010-06-10 2019-04-02 CGRP ellenanyagok

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE11792989A HUE038135T2 (hu) 2010-06-10 2011-06-07 CGRP ellenanyagok

Country Status (34)

Country Link
US (3) US9073991B2 (hu)
EP (2) EP2579894B1 (hu)
JP (2) JP6021806B2 (hu)
KR (1) KR101489566B1 (hu)
CN (2) CN104292332B (hu)
AR (1) AR081434A1 (hu)
AU (1) AU2011265050B2 (hu)
BR (1) BR112012031501B1 (hu)
CA (1) CA2802102C (hu)
CY (2) CY1119789T1 (hu)
DK (1) DK2579894T3 (hu)
EA (1) EA022931B1 (hu)
ES (2) ES2656000T3 (hu)
HK (1) HK1203211A1 (hu)
HR (1) HRP20171992T1 (hu)
HU (2) HUE038135T2 (hu)
IL (2) IL222885B (hu)
JO (1) JO3330B1 (hu)
LT (2) LT2579894T (hu)
LU (1) LUC00112I2 (hu)
ME (1) ME02862B (hu)
MX (2) MX363209B (hu)
NL (1) NL300979I2 (hu)
NO (2) NO2579894T3 (hu)
NZ (1) NZ603607A (hu)
PL (1) PL2579894T3 (hu)
PT (1) PT2579894T (hu)
RS (1) RS56638B1 (hu)
SG (1) SG185648A1 (hu)
SI (1) SI2579894T1 (hu)
TW (1) TWI423818B (hu)
UA (1) UA109658C2 (hu)
WO (1) WO2011156324A1 (hu)
ZA (1) ZA201208996B (hu)

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ES2664421T3 (es) 2005-11-14 2018-04-19 Teva Pharmaceuticals International Gmbh Anticuerpo antagonista dirigido contra un péptido relacionado con el gen de la calcitonina
US8293239B2 (en) 2008-03-04 2012-10-23 Pfizer Limited Methods of treating chronic pain
WO2011024113A1 (en) 2009-08-28 2011-03-03 Rinat Neuroscience Corporation Methods for treating visceral pain by administering antagonist antibodies directed against calcitonin gene-related peptide
AR081434A1 (es) * 2010-06-10 2012-08-29 Lilly Co Eli Anticuerpo del peptido relacionado con el gen calcitonina (cgrp), composicion farmaceutica que lo comprende, uso de dicho anticuerpo para preparar un medicamento util para tratar dolor de osteoartritis o migranas y fragmento de union a antigeno de dicho anticuerpo
KR102098546B1 (ko) 2011-05-20 2020-04-07 앨더바이오 홀딩스 엘엘씨 필요한 대상체, 특히 편두통 환자의 광선공포증 또는 광선 혐오증을 예방 또는 억제하기 위한 항-cgrp 항체 및 항체 단편의 용도
CN103957935B (zh) 2011-05-20 2018-04-03 奥尔德生物控股有限责任公司 抗cgrp或抗cgrp‑r抗体或抗体片段用于治疗或预防慢性和急性形式的腹泻的用途
CN108373502B (zh) * 2011-05-20 2022-03-22 H.伦德贝克公司 抗cgrp组合物及其用途
CN104662044B (zh) 2012-08-24 2018-10-30 加利福尼亚大学董事会 用于治疗ror1癌症并抑制转移的抗体和疫苗
DK3119431T3 (da) 2014-03-21 2024-03-18 Teva Pharmaceuticals Int Gmbh Antagonistantistoffer rettet mod calcitoningen-relateret peptid og fremgangsmåder til anvendelse deraf
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
BR112017008160A8 (pt) 2014-10-24 2023-04-11 Merck Sharp & Dohme Peptídeo, composição, métodos para tratamento de um paciente ou indivíduo e para tratamento de uma doença metabólica, e, usos de um peptídeo e de uma composição
TWI595006B (zh) * 2014-12-09 2017-08-11 禮納特神經系統科學公司 抗pd-1抗體類和使用彼等之方法
JOP20200116A1 (ar) 2015-04-24 2017-06-16 Amgen Inc طرق لعلاج أو الوقاية من الصداع النصفي
AR104847A1 (es) * 2015-06-17 2017-08-16 Lilly Co Eli Formulación de anticuerpo anti-cgrp
AU2015413277A1 (en) * 2015-10-30 2018-04-12 Eli Lilly And Company Anti-CGRP/anti-IL-23 bispecific antibodies and uses thereof
CN105483091A (zh) * 2015-12-29 2016-04-13 天津三箭生物技术股份有限公司 小鼠抗人Calcitonin单克隆抗体及分泌该单克隆抗体的杂交瘤细胞株
KR20180091930A (ko) * 2016-01-28 2018-08-16 일라이 릴리 앤드 캄파니 Cgrp 항체 및 그의 용도
AU2017214277B2 (en) 2016-02-01 2020-02-27 Eli Lilly And Company Parathyroid hormone – anti-RANKL antibody fusion compounds
AU2017289270B2 (en) 2016-06-27 2023-05-04 The Regents Of The University Of California Cancer treatment combinations
EA201990548A1 (ru) 2016-09-23 2019-09-30 Тева Фармасьютикалз Интернэшнл Гмбх Лечение кластерной головной боли
EP3515937A1 (en) 2016-09-23 2019-07-31 Teva Pharmaceuticals International GmbH Treating refractory migraine
KR20190133174A (ko) * 2017-03-02 2019-12-02 베쓰 이스라엘 디코니스 메디칼 센터 인크 칼시토닌 유전자 관련 펩티드에 대해 지시되는 항체에 반응하는 두통 환자를 선택하는 방법
AR111845A1 (es) * 2017-05-03 2019-08-28 Lilly Co Eli Anticuerpos biespecíficos anti-cgrp / anti-il-23 y usos de los mismos
MX2019015304A (es) * 2017-06-21 2020-02-17 Cephalon Inc Amortiguador de lavado para cromatografia de intercambio cationico.
TWI754772B (zh) * 2017-09-06 2022-02-11 美商美國禮來大藥廠 用於治療偏頭痛之拉米迪坦(lasmiditan)與cgrp拮抗劑之組合療法
MX2020006976A (es) 2018-01-12 2020-10-05 Amgen Inc Anticuerpos del receptor de tipo i del polipeptido activador de la adenilato?ciclasa hipofisaria (pac1) y sus usos.
WO2019231800A1 (en) 2018-05-31 2019-12-05 Eli Lilly And Company Anti-cgrp antibodies for treating menstrual-related migraines
MA53436A (fr) 2018-08-22 2021-12-01 Lilly Co Eli Anticorps anti-cgrp pour patients résistants au traitement
US11639380B2 (en) 2019-01-08 2023-05-02 H. Lundbeck A/S Acute treatment and rapid treatment of headache using anti-CGRP antibodies
EP3744400A1 (en) * 2019-05-28 2020-12-02 Etablissement Français du Sang Car-t cells targeting il-1rap and their use in acute myeloid leukemia (aml)
CN114127110B (zh) * 2019-05-30 2022-07-01 山东博安生物技术股份有限公司 抗cgrp抗体及其应用
EP4045641A1 (en) 2019-10-15 2022-08-24 Eli Lilly and Company Recombinantly engineered, lipase/esterase-deficient mammalian cell lines
EP4301362A1 (en) 2021-03-02 2024-01-10 CGRP Diagnostics GmbH Treatment and/or reduction of occurrence of migraine
WO2023161526A1 (en) 2022-02-28 2023-08-31 Tridem Bioscience Gmbh & Co Kg A CONJUGATE CONSISTING OF OR COMPRISING AT LEAST A ß-GLUCAN OR A MANNAN
CN117586390A (zh) * 2022-08-11 2024-02-23 上海君实生物医药科技股份有限公司 抗cgrp抗体及用途

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GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
ES2134212T3 (es) * 1991-04-25 1999-10-01 Chugai Pharmaceutical Co Ltd Anticuerpo humano reconstituido contra el receptor de la interleuquina 6 humano.
ES2206447T3 (es) * 1991-06-14 2004-05-16 Genentech, Inc. Anticuerpo humanizado para heregulina.
WO2005035753A1 (ja) 2003-10-10 2005-04-21 Chugai Seiyaku Kabushiki Kaisha 機能蛋白質を代替する二重特異性抗体
JP4976376B2 (ja) 2005-04-08 2012-07-18 メディミューン,エルエルシー 哺乳動物メタニューモウイルスに対する抗体
ES2664421T3 (es) 2005-11-14 2018-04-19 Teva Pharmaceuticals International Gmbh Anticuerpo antagonista dirigido contra un péptido relacionado con el gen de la calcitonina
WO2007076336A1 (en) * 2005-12-22 2007-07-05 Eli Lilly And Company Treatment of migraine with anti-cgrp antibodies
US8293239B2 (en) * 2008-03-04 2012-10-23 Pfizer Limited Methods of treating chronic pain
ES2584907T3 (es) 2008-03-04 2016-09-30 Labrys Biologics Inc. Métodos para tratamiento del dolor inflamatorio
AR081434A1 (es) * 2010-06-10 2012-08-29 Lilly Co Eli Anticuerpo del peptido relacionado con el gen calcitonina (cgrp), composicion farmaceutica que lo comprende, uso de dicho anticuerpo para preparar un medicamento util para tratar dolor de osteoartritis o migranas y fragmento de union a antigeno de dicho anticuerpo

Also Published As

Publication number Publication date
EP2579894A1 (en) 2013-04-17
TWI423818B (zh) 2014-01-21
JO3330B1 (ar) 2019-03-13
CY2019017I1 (el) 2020-05-29
EA201270769A1 (ru) 2013-04-30
KR20130034024A (ko) 2013-04-04
JP6021806B2 (ja) 2016-11-09
US20110305711A1 (en) 2011-12-15
CA2802102C (en) 2016-07-26
CY2019017I2 (el) 2020-05-29
EP2579894B1 (en) 2017-11-22
HUE038135T2 (hu) 2018-09-28
LT2579894T (lt) 2018-02-26
NO2019017I1 (no) 2019-04-05
LUC00112I2 (hu) 2019-12-27
US20150259415A1 (en) 2015-09-17
SI2579894T1 (en) 2018-01-31
EP3318272A1 (en) 2018-05-09
ZA201208996B (en) 2014-05-28
AR081434A1 (es) 2012-08-29
JP2017014203A (ja) 2017-01-19
BR112012031501B1 (pt) 2020-02-11
CY1119789T1 (el) 2018-06-27
NO2579894T3 (hu) 2018-04-21
ES2930321T3 (es) 2022-12-09
ES2656000T3 (es) 2018-02-22
DK2579894T3 (en) 2018-01-15
BR112012031501A2 (pt) 2016-10-25
CA2802102A1 (en) 2011-12-15
CN104292332A (zh) 2015-01-21
US9073991B2 (en) 2015-07-07
IL222885B (en) 2019-09-26
JP6466883B2 (ja) 2019-02-06
EP3318272B1 (en) 2022-08-10
LUC00112I1 (hu) 2019-04-10
US20170073403A1 (en) 2017-03-16
ME02862B (me) 2018-04-20
MX363209B (es) 2019-03-14
US9505838B2 (en) 2016-11-29
CN102946905A (zh) 2013-02-27
LTPA2019011I1 (lt) 2019-05-10
PL2579894T3 (pl) 2018-04-30
HRP20171992T1 (hr) 2018-02-09
AU2011265050A1 (en) 2012-11-08
UA109658C2 (xx) 2015-09-25
IL242409B (en) 2020-07-30
MX2012014480A (es) 2013-02-07
HK1203211A1 (en) 2015-10-23
EA022931B1 (ru) 2016-03-31
RS56638B1 (sr) 2018-03-30
EP2579894A4 (en) 2013-12-04
MX340999B (es) 2016-08-03
CN102946905B (zh) 2014-10-15
NL300979I1 (nl) 2019-04-17
PT2579894T (pt) 2018-02-06
NZ603607A (en) 2014-09-26
IL222885A0 (en) 2012-12-31
TW201210618A (en) 2012-03-16
SG185648A1 (en) 2012-12-28
LTC2579894I2 (lt) 2020-03-25
KR101489566B1 (ko) 2015-02-03
JP2013532143A (ja) 2013-08-15
AU2011265050B2 (en) 2013-06-27
NL300979I2 (nl) 2019-07-11
CN104292332B (zh) 2019-11-01
WO2011156324A1 (en) 2011-12-15

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