MX2020006976A - Anticuerpos del receptor de tipo i del polipeptido activador de la adenilato?ciclasa hipofisaria (pac1) y sus usos. - Google Patents

Anticuerpos del receptor de tipo i del polipeptido activador de la adenilato?ciclasa hipofisaria (pac1) y sus usos.

Info

Publication number
MX2020006976A
MX2020006976A MX2020006976A MX2020006976A MX2020006976A MX 2020006976 A MX2020006976 A MX 2020006976A MX 2020006976 A MX2020006976 A MX 2020006976A MX 2020006976 A MX2020006976 A MX 2020006976A MX 2020006976 A MX2020006976 A MX 2020006976A
Authority
MX
Mexico
Prior art keywords
antibodies
pac1
neutralizing antibodies
pac1 antibodies
headache
Prior art date
Application number
MX2020006976A
Other languages
English (en)
Inventor
Mark Leo Michaels
Agnes Eva Hamburger
Cen Xu
Derek E Piper
Neeraj Jagdish Agrawal
Zhulun Wang
Irwin Chen
su Chong
Bryna Fuchslocher
Kevin Graham
Christopher Mohr
Kenneth William Walker
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MX2020006976A publication Critical patent/MX2020006976A/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • A61K38/22—Hormones
    • A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
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Abstract

La presente invención se refiere a anticuerpos neutralizantes del receptor de tipo I del polipéptido activador de la adenilato·ciclasa hipofisaria (PAC1) humano y composiciones farmacéuticas que comprenden tales anticuerpos. También se describen métodos para tratar o prevenir afecciones que producen cefaleas, tales como migraña y cefalea en brotes, usando los anticuerpos neutralizantes.
MX2020006976A 2018-01-12 2019-01-11 Anticuerpos del receptor de tipo i del polipeptido activador de la adenilato?ciclasa hipofisaria (pac1) y sus usos. MX2020006976A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862617157P 2018-01-12 2018-01-12
PCT/US2019/013227 WO2019140216A1 (en) 2018-01-12 2019-01-11 Pac1 antibodies and uses thereof

Publications (1)

Publication Number Publication Date
MX2020006976A true MX2020006976A (es) 2020-10-05

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US (3) US10738110B2 (es)
EP (1) EP3737699A1 (es)
JP (2) JP7339262B2 (es)
KR (1) KR20200110362A (es)
CN (1) CN111566126A (es)
AR (1) AR114080A1 (es)
AU (1) AU2019207915A1 (es)
BR (1) BR112020013621A2 (es)
CA (1) CA3087951A1 (es)
CL (1) CL2020001846A1 (es)
IL (1) IL275794A (es)
MX (1) MX2020006976A (es)
SG (1) SG11202006610YA (es)
UY (1) UY38050A (es)
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WO2021142413A1 (en) * 2020-01-12 2021-07-15 Vanderbilt University Human antibodies to crimean congo hemorrhagic fever virus
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