LUC00112I2 - - Google Patents

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Publication number
LUC00112I2
LUC00112I2 LU00112C LUC00112C LUC00112I2 LU C00112 I2 LUC00112 I2 LU C00112I2 LU 00112 C LU00112 C LU 00112C LU C00112 C LUC00112 C LU C00112C LU C00112 I2 LUC00112 I2 LU C00112I2
Authority
LU
Luxembourg
Application number
LU00112C
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of LUC00112I1 publication Critical patent/LUC00112I1/fr
Publication of LUC00112I2 publication Critical patent/LUC00112I2/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57527Calcitonin gene related peptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57545Neuropeptide Y
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57563Vasoactive intestinal peptide [VIP]; Related peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
LU00112C 2010-06-10 2019-04-09 LUC00112I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35332310P 2010-06-10 2010-06-10
PCT/US2011/039381 WO2011156324A1 (fr) 2010-06-10 2011-06-07 Anticorps anti-cgrp

Publications (2)

Publication Number Publication Date
LUC00112I1 LUC00112I1 (fr) 2019-04-10
LUC00112I2 true LUC00112I2 (fr) 2019-12-27

Family

ID=45096388

Family Applications (1)

Application Number Title Priority Date Filing Date
LU00112C LUC00112I2 (fr) 2010-06-10 2019-04-09

Country Status (34)

Country Link
US (3) US9073991B2 (fr)
EP (2) EP2579894B1 (fr)
JP (2) JP6021806B2 (fr)
KR (1) KR101489566B1 (fr)
CN (2) CN102946905B (fr)
AR (1) AR081434A1 (fr)
AU (1) AU2011265050B2 (fr)
BR (1) BR112012031501B1 (fr)
CA (1) CA2802102C (fr)
CY (2) CY1119789T1 (fr)
DK (1) DK2579894T3 (fr)
EA (1) EA022931B1 (fr)
ES (2) ES2656000T3 (fr)
HK (1) HK1203211A1 (fr)
HR (1) HRP20171992T1 (fr)
HU (2) HUE038135T2 (fr)
IL (2) IL222885B (fr)
JO (1) JO3330B1 (fr)
LT (2) LT2579894T (fr)
LU (1) LUC00112I2 (fr)
ME (1) ME02862B (fr)
MX (2) MX363209B (fr)
NL (1) NL300979I2 (fr)
NO (2) NO2579894T3 (fr)
NZ (1) NZ603607A (fr)
PL (1) PL2579894T3 (fr)
PT (1) PT2579894T (fr)
RS (1) RS56638B1 (fr)
SG (1) SG185648A1 (fr)
SI (1) SI2579894T1 (fr)
TW (1) TWI423818B (fr)
UA (1) UA109658C2 (fr)
WO (1) WO2011156324A1 (fr)
ZA (1) ZA201208996B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101309704B (zh) 2005-11-14 2012-10-10 礼纳特神经系统科学公司 针对降钙素基因相关肽的拮抗剂抗体及其使用方法
CA2716424C (fr) 2008-03-04 2015-04-28 Pfizer Limited Procedes de traitement d'une douleur chronique
AU2010288194B2 (en) 2009-08-28 2013-08-29 Teva Pharmaceuticals International Gmbh Methods for treating visceral pain by administering antagonist antibodies directed against calcitonin gene-related peptide
AR081434A1 (es) * 2010-06-10 2012-08-29 Lilly Co Eli Anticuerpo del peptido relacionado con el gen calcitonina (cgrp), composicion farmaceutica que lo comprende, uso de dicho anticuerpo para preparar un medicamento util para tratar dolor de osteoartritis o migranas y fragmento de union a antigeno de dicho anticuerpo
DK2709663T3 (da) 2011-05-20 2019-05-20 Alderbio Holdings Llc Anvendelse af anti-CGRP-antistoffer og antistoffragmenter til forebyggelse eller inhibering af fotofobi eller aversion mod lys hos individer med behov herfor, især migrænikere
AU2012258976B8 (en) 2011-05-20 2017-07-20 H. Lundbeck A/S Use of anti-CGRP or anti-CGRP-R antibodies or antibody fragments to treat or prevent chronic and acute forms of diarrhea
HUE055505T2 (hu) 2011-05-20 2021-11-29 H Lundbeck As Anti-CGRP készítmények és alkalmazásuk
PL2888283T3 (pl) 2012-08-24 2019-03-29 The Regents Of The University Of California Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
US9896502B2 (en) * 2014-03-21 2018-02-20 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
SG11201703238TA (en) 2014-10-24 2017-05-30 Merck Sharp & Dohme Co-agonists of the glucagon and glp-1 receptors
TWI595006B (zh) * 2014-12-09 2017-08-11 禮納特神經系統科學公司 抗pd-1抗體類和使用彼等之方法
JOP20200116A1 (ar) 2015-04-24 2017-06-16 Amgen Inc طرق لعلاج أو الوقاية من الصداع النصفي
AR104847A1 (es) 2015-06-17 2017-08-16 Lilly Co Eli Formulación de anticuerpo anti-cgrp
JP6592600B2 (ja) * 2015-10-30 2019-10-16 イーライ リリー アンド カンパニー 抗cgrp/抗il−23二重特異性抗体及びその使用
CN105483091A (zh) * 2015-12-29 2016-04-13 天津三箭生物技术股份有限公司 小鼠抗人Calcitonin单克隆抗体及分泌该单克隆抗体的杂交瘤细胞株
WO2017132062A1 (fr) * 2016-01-28 2017-08-03 Eli Lilly And Company Anticorps anti-cgrp et leurs utilisations
EP3411066A1 (fr) 2016-02-01 2018-12-12 Eli Lilly and Company Composés de fusion parathormone-anticorps anti-rankl
US10688181B2 (en) 2016-06-27 2020-06-23 The Regents Of The University Of California Cancer treatment combinations
KR20190066607A (ko) * 2016-09-23 2019-06-13 테바 파마슈티컬스 인터내셔널 게엠베하 불응성 편두통의 치료
AU2017331592A1 (en) 2016-09-23 2019-04-11 Teva Pharmaceuticals International Gmbh Treating cluster headache
US20190071490A1 (en) 2017-03-02 2019-03-07 Beth Israel Deaconess Medical Center, Inc. Preventing Post-Ictal Headaches
AR111845A1 (es) 2017-05-03 2019-08-28 Lilly Co Eli Anticuerpos biespecíficos anti-cgrp / anti-il-23 y usos de los mismos
MX2019015304A (es) * 2017-06-21 2020-02-17 Cephalon Inc Amortiguador de lavado para cromatografia de intercambio cationico.
TWI754772B (zh) * 2017-09-06 2022-02-11 美商美國禮來大藥廠 用於治療偏頭痛之拉米迪坦(lasmiditan)與cgrp拮抗劑之組合療法
TWI831762B (zh) 2018-01-12 2024-02-11 美商安進公司 Pac1抗體及其用途
WO2019231800A1 (fr) 2018-05-31 2019-12-05 Eli Lilly And Company Anticorps anti-cgrp pour le traitement des migraines liées aux menstruations
US20210340230A1 (en) 2018-08-22 2021-11-04 Eli Lilly And Company Anti-CGRP Antibodies For Treatment-Resistant Patients
MX2021008267A (es) 2019-01-08 2021-08-05 H Lundbeck As Tratamiento agudo y tratamiento rapido de la cefalea usando anticuerpos anti-cgrp.
EP3744400A1 (fr) * 2019-05-28 2020-12-02 Etablissement Français du Sang Ciblage de cellules car-t il-1rap et leur utilisation dans la leucémie myéloïde aiguë (aml)
WO2020239014A1 (fr) * 2019-05-30 2020-12-03 山东博安生物技术有限公司 Anticorps anti cgrp et son utilisation
CN114555792A (zh) 2019-10-15 2022-05-27 伊莱利利公司 重组改造的、脂肪酶/酯酶缺陷型哺乳动物细胞系
KR20230157986A (ko) 2021-03-02 2023-11-17 체게에르페 다이어그노스틱스 게엠베하 편투통 발생의 치료 및/또는 저감
WO2023161526A1 (fr) 2022-02-28 2023-08-31 Tridem Bioscience Gmbh & Co Kg Conjugué constitué de ou comprenant au moins un ss-glucane ou un mannane
WO2024032750A1 (fr) * 2022-08-11 2024-02-15 上海君实生物医药科技股份有限公司 Anticorps anti-cgrp et utilisation
CN118271438A (zh) * 2024-05-27 2024-07-02 上海宏成药业有限公司 抗cgrp抗体或其抗原结合片段及其用途

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
AU668349B2 (en) * 1991-04-25 1996-05-02 Chugai Seiyaku Kabushiki Kaisha Reconstituted human antibody against human interleukin 6 receptor
DK0590058T3 (da) * 1991-06-14 2004-03-29 Genentech Inc Humaniseret heregulin-antistof
AU2003271174A1 (en) 2003-10-10 2005-04-27 Chugai Seiyaku Kabushiki Kaisha Double specific antibodies substituting for functional protein
WO2006110214A2 (fr) * 2005-04-08 2006-10-19 Medimmune, Inc. Anticorps diriges contre le metapneumovirus du mammifere
CN101309704B (zh) * 2005-11-14 2012-10-10 礼纳特神经系统科学公司 针对降钙素基因相关肽的拮抗剂抗体及其使用方法
WO2007076336A1 (fr) 2005-12-22 2007-07-05 Eli Lilly And Company Traitement de la migraine avec des anticorps anti-cgrp
CA2716424C (fr) * 2008-03-04 2015-04-28 Pfizer Limited Procedes de traitement d'une douleur chronique
KR101304085B1 (ko) 2008-03-04 2013-09-05 라브리스 바이올로직스 인코포레이티드 염증성 통증의 치료 방법
AR081434A1 (es) * 2010-06-10 2012-08-29 Lilly Co Eli Anticuerpo del peptido relacionado con el gen calcitonina (cgrp), composicion farmaceutica que lo comprende, uso de dicho anticuerpo para preparar un medicamento util para tratar dolor de osteoartritis o migranas y fragmento de union a antigeno de dicho anticuerpo

Also Published As

Publication number Publication date
HK1203211A1 (en) 2015-10-23
JP2013532143A (ja) 2013-08-15
US20150259415A1 (en) 2015-09-17
HUS1900020I1 (hu) 2019-05-28
LTC2579894I2 (lt) 2020-03-25
EA022931B1 (ru) 2016-03-31
JP2017014203A (ja) 2017-01-19
JP6466883B2 (ja) 2019-02-06
EA201270769A1 (ru) 2013-04-30
HUE038135T2 (hu) 2018-09-28
EP3318272B1 (fr) 2022-08-10
CY2019017I1 (el) 2020-05-29
ME02862B (fr) 2018-04-20
NO2579894T3 (fr) 2018-04-21
ZA201208996B (en) 2014-05-28
NL300979I2 (nl) 2019-07-11
WO2011156324A1 (fr) 2011-12-15
US20110305711A1 (en) 2011-12-15
PL2579894T3 (pl) 2018-04-30
US9505838B2 (en) 2016-11-29
CN102946905A (zh) 2013-02-27
PT2579894T (pt) 2018-02-06
UA109658C2 (xx) 2015-09-25
CY2019017I2 (el) 2020-05-29
CN102946905B (zh) 2014-10-15
JP6021806B2 (ja) 2016-11-09
CA2802102A1 (fr) 2011-12-15
NL300979I1 (nl) 2019-04-17
CN104292332B (zh) 2019-11-01
MX363209B (es) 2019-03-14
MX340999B (es) 2016-08-03
NO2019017I1 (no) 2019-04-05
JO3330B1 (ar) 2019-03-13
IL222885B (en) 2019-09-26
CN104292332A (zh) 2015-01-21
IL242409B (en) 2020-07-30
LT2579894T (lt) 2018-02-26
LUC00112I1 (fr) 2019-04-10
AU2011265050B2 (en) 2013-06-27
KR20130034024A (ko) 2013-04-04
DK2579894T3 (en) 2018-01-15
US20170073403A1 (en) 2017-03-16
ES2930321T3 (es) 2022-12-09
BR112012031501B1 (pt) 2020-02-11
AR081434A1 (es) 2012-08-29
LTPA2019011I1 (lt) 2019-05-10
EP2579894A4 (fr) 2013-12-04
KR101489566B1 (ko) 2015-02-03
BR112012031501A2 (pt) 2016-10-25
EP3318272A1 (fr) 2018-05-09
HRP20171992T1 (hr) 2018-02-09
SI2579894T1 (en) 2018-01-31
TWI423818B (zh) 2014-01-21
RS56638B1 (sr) 2018-03-30
CY1119789T1 (el) 2018-06-27
EP2579894A1 (fr) 2013-04-17
NZ603607A (en) 2014-09-26
SG185648A1 (en) 2012-12-28
TW201210618A (en) 2012-03-16
CA2802102C (fr) 2016-07-26
AU2011265050A1 (en) 2012-11-08
MX2012014480A (es) 2013-02-07
ES2656000T3 (es) 2018-02-22
IL222885A0 (en) 2012-12-31
US9073991B2 (en) 2015-07-07
EP2579894B1 (fr) 2017-11-22

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