LUC00112I1 - - Google Patents

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Publication number
LUC00112I1
LUC00112I1 LUC00112C LUC00112I1 LU C00112 I1 LUC00112 I1 LU C00112I1 LU C00112 C LUC00112 C LU C00112C LU C00112 I1 LUC00112 I1 LU C00112I1
Authority
LU
Luxembourg
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of LUC00112I1 publication Critical patent/LUC00112I1/fr
Publication of LUC00112I2 publication Critical patent/LUC00112I2/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57527Calcitonin gene related peptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57545Neuropeptide Y
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57563Vasoactive intestinal peptide [VIP]; Related peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
LU00112C 2010-06-10 2019-04-09 LUC00112I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35332310P 2010-06-10 2010-06-10
PCT/US2011/039381 WO2011156324A1 (fr) 2010-06-10 2011-06-07 Anticorps anti-cgrp

Publications (2)

Publication Number Publication Date
LUC00112I1 true LUC00112I1 (fr) 2019-04-10
LUC00112I2 LUC00112I2 (fr) 2019-12-27

Family

ID=45096388

Family Applications (1)

Application Number Title Priority Date Filing Date
LU00112C LUC00112I2 (fr) 2010-06-10 2019-04-09

Country Status (34)

Country Link
US (3) US9073991B2 (fr)
EP (2) EP2579894B1 (fr)
JP (2) JP6021806B2 (fr)
KR (1) KR101489566B1 (fr)
CN (2) CN102946905B (fr)
AR (1) AR081434A1 (fr)
AU (1) AU2011265050B2 (fr)
BR (1) BR112012031501B1 (fr)
CA (1) CA2802102C (fr)
CY (2) CY1119789T1 (fr)
DK (1) DK2579894T3 (fr)
EA (1) EA022931B1 (fr)
ES (2) ES2656000T3 (fr)
HK (1) HK1203211A1 (fr)
HR (1) HRP20171992T1 (fr)
HU (2) HUE038135T2 (fr)
IL (2) IL222885B (fr)
JO (1) JO3330B1 (fr)
LT (2) LT2579894T (fr)
LU (1) LUC00112I2 (fr)
ME (1) ME02862B (fr)
MX (2) MX363209B (fr)
NL (1) NL300979I2 (fr)
NO (2) NO2579894T3 (fr)
NZ (1) NZ603607A (fr)
PL (1) PL2579894T3 (fr)
PT (1) PT2579894T (fr)
RS (1) RS56638B1 (fr)
SG (1) SG185648A1 (fr)
SI (1) SI2579894T1 (fr)
TW (1) TWI423818B (fr)
UA (1) UA109658C2 (fr)
WO (1) WO2011156324A1 (fr)
ZA (1) ZA201208996B (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2380592T3 (pl) 2005-11-14 2018-07-31 Teva Pharmaceuticals International Gmbh Przeciwciało antagonistyczne skierowane przeciwko peptydowi powiązanemu z genem kalcytoniny
WO2009109911A1 (fr) 2008-03-04 2009-09-11 Pfizer Limited Procédés de traitement d'une douleur chronique
RU2535074C2 (ru) 2009-08-28 2014-12-10 Лэйбрис Байолоджикс, Инк. Способы лечения висцеральной боли путем введения антител-антагонистов, направленных против пептида, связанного с геном кальцитонина
AR081434A1 (es) * 2010-06-10 2012-08-29 Lilly Co Eli Anticuerpo del peptido relacionado con el gen calcitonina (cgrp), composicion farmaceutica que lo comprende, uso de dicho anticuerpo para preparar un medicamento util para tratar dolor de osteoartritis o migranas y fragmento de union a antigeno de dicho anticuerpo
US9708393B2 (en) 2011-05-20 2017-07-18 Alderbio Holdings Llc Use of anti-CGRP antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers
CN107602700B (zh) 2011-05-20 2021-12-17 H.伦德贝克公司 抗cgrp组合物及其用途
MX365813B (es) 2011-05-20 2019-06-14 Alderbio Holdings Llc Uso de anticuerpos anti-cgrp o anti-cgrp o fragmentos de anticuerpo para tratar o prevenir formas crónicas y agudas de diarrea.
US9758591B2 (en) 2012-08-24 2017-09-12 The Regents Of The University Of California Antibodies and vaccines for use in treating ROR1 cancers and inhibiting metastasis
US10556945B2 (en) * 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
LT3119431T (lt) 2014-03-21 2024-03-12 Teva Pharmaceuticals International Gmbh Antagonistiniai antikūnai, nukreipti prieš peptidą, susijusį su kalcitonino genu, ir jų panaudojimo būdai
EP3825324A1 (fr) 2014-10-24 2021-05-26 Merck Sharp & Dohme Corp. Co-agonistes des récepteurs du glucagon et du glp-1
TWI595006B (zh) * 2014-12-09 2017-08-11 禮納特神經系統科學公司 抗pd-1抗體類和使用彼等之方法
JOP20200116A1 (ar) 2015-04-24 2017-06-16 Amgen Inc طرق لعلاج أو الوقاية من الصداع النصفي
AR104847A1 (es) * 2015-06-17 2017-08-16 Lilly Co Eli Formulación de anticuerpo anti-cgrp
WO2017074428A1 (fr) * 2015-10-30 2017-05-04 Eli Lilly And Company Anticorps bispécifiques anti-cgrp/anti-il-23 et leurs utilisations
CN105483091A (zh) * 2015-12-29 2016-04-13 天津三箭生物技术股份有限公司 小鼠抗人Calcitonin单克隆抗体及分泌该单克隆抗体的杂交瘤细胞株
US20190031748A1 (en) * 2016-01-28 2019-01-31 Eli Lilly And Company Cgrp antibodies and uses thereof
AU2017214277B2 (en) 2016-02-01 2020-02-27 Eli Lilly And Company Parathyroid hormone – anti-RANKL antibody fusion compounds
KR20240113990A (ko) 2016-06-27 2024-07-23 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 암 치료 조합
US20180111984A1 (en) 2016-09-23 2018-04-26 Teva Pharmaceuticals International Gmbh Treating cluster headache
CN109952314A (zh) 2016-09-23 2019-06-28 泰瓦制药国际有限公司 治疗难治性偏头痛
JP7195262B2 (ja) * 2017-03-02 2022-12-23 ベス イスラエル デアコネス メディカル センター インコーポレイティッド カルシトニン遺伝子関連ペプチドを指向する抗体に応答性の頭痛患者の選択方法
TW201902926A (zh) 2017-05-03 2019-01-16 美商美國禮來大藥廠 抗cgrp/抗il-23雙特異性抗體及其用途
WO2018237159A1 (fr) * 2017-06-21 2018-12-27 Cephalon, Inc. Tampon de lavage pour chromatographie d'échange cationique
TWI754772B (zh) * 2017-09-06 2022-02-11 美商美國禮來大藥廠 用於治療偏頭痛之拉米迪坦(lasmiditan)與cgrp拮抗劑之組合療法
MX2020006976A (es) 2018-01-12 2020-10-05 Amgen Inc Anticuerpos del receptor de tipo i del polipeptido activador de la adenilato?ciclasa hipofisaria (pac1) y sus usos.
WO2019231800A1 (fr) 2018-05-31 2019-12-05 Eli Lilly And Company Anticorps anti-cgrp pour le traitement des migraines liées aux menstruations
JP2021534197A (ja) 2018-08-22 2021-12-09 イーライ リリー アンド カンパニー 治療抵抗性患者のための抗cgrp抗体
CA3123237A1 (fr) 2019-01-08 2020-07-16 H. Lundbeck A/S Traitement aigu et traitement rapide de maux de tete a l'aide d'anticorps anti-cgrp
EP3744400A1 (fr) * 2019-05-28 2020-12-02 Etablissement Français du Sang Ciblage de cellules car-t il-1rap et leur utilisation dans la leucémie myéloïde aiguë (aml)
CN114127110B (zh) * 2019-05-30 2022-07-01 山东博安生物技术股份有限公司 抗cgrp抗体及其应用
JP2022552323A (ja) 2019-10-15 2022-12-15 イーライ リリー アンド カンパニー 組換え操作された、リパーゼ/エステラーゼ欠損哺乳動物細胞株
WO2022185224A1 (fr) 2021-03-02 2022-09-09 Mark Hasleton Traitement et/ou réduction de l'apparition de migraine
WO2023161526A1 (fr) 2022-02-28 2023-08-31 Tridem Bioscience Gmbh & Co Kg Conjugué constitué de ou comprenant au moins un ss-glucane ou un mannane
WO2024032750A1 (fr) * 2022-08-11 2024-02-15 上海君实生物医药科技股份有限公司 Anticorps anti-cgrp et utilisation
CN118271438B (zh) * 2024-05-27 2024-08-30 上海宏成药业有限公司 抗cgrp抗体或其抗原结合片段及其用途

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GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
RU2139351C1 (ru) * 1991-04-25 1999-10-10 Чугаи Сейяку Кабусики Кайся Н- и l-цепи моноклонального антитела рм1 (монат) к рецептору il-6r человека и их v-области, модифицированная монат, его н- и l-цепи и их v-области, cdr- последовательности, днк-последовательности
ES2206447T3 (es) * 1991-06-14 2004-05-16 Genentech, Inc. Anticuerpo humanizado para heregulina.
WO2005035753A1 (fr) * 2003-10-10 2005-04-21 Chugai Seiyaku Kabushiki Kaisha Anticorps a double specificite remplaçant une proteine fonctionnelle
EP1885402A4 (fr) * 2005-04-08 2010-11-10 Medimmune Inc Anticorps diriges contre le metapneumovirus du mammifere
PL2380592T3 (pl) * 2005-11-14 2018-07-31 Teva Pharmaceuticals International Gmbh Przeciwciało antagonistyczne skierowane przeciwko peptydowi powiązanemu z genem kalcytoniny
WO2007076336A1 (fr) * 2005-12-22 2007-07-05 Eli Lilly And Company Traitement de la migraine avec des anticorps anti-cgrp
CA2716799C (fr) * 2008-03-04 2018-05-22 Pfizer Limited Procedes de traitement d'une douleur inflammatoire
WO2009109911A1 (fr) * 2008-03-04 2009-09-11 Pfizer Limited Procédés de traitement d'une douleur chronique
AR081434A1 (es) * 2010-06-10 2012-08-29 Lilly Co Eli Anticuerpo del peptido relacionado con el gen calcitonina (cgrp), composicion farmaceutica que lo comprende, uso de dicho anticuerpo para preparar un medicamento util para tratar dolor de osteoartritis o migranas y fragmento de union a antigeno de dicho anticuerpo

Also Published As

Publication number Publication date
PT2579894T (pt) 2018-02-06
CY2019017I2 (el) 2020-05-29
CY1119789T1 (el) 2018-06-27
NO2019017I1 (no) 2019-04-05
HRP20171992T1 (hr) 2018-02-09
NL300979I2 (nl) 2019-07-11
BR112012031501A2 (pt) 2016-10-25
LTC2579894I2 (lt) 2020-03-25
LTPA2019011I1 (lt) 2019-05-10
EP2579894A4 (fr) 2013-12-04
EP2579894B1 (fr) 2017-11-22
SG185648A1 (en) 2012-12-28
LT2579894T (lt) 2018-02-26
US9073991B2 (en) 2015-07-07
HUS1900020I1 (hu) 2019-05-28
MX2012014480A (es) 2013-02-07
AU2011265050B2 (en) 2013-06-27
JP2013532143A (ja) 2013-08-15
DK2579894T3 (en) 2018-01-15
ES2656000T3 (es) 2018-02-22
JP6466883B2 (ja) 2019-02-06
CA2802102A1 (fr) 2011-12-15
CA2802102C (fr) 2016-07-26
NO2579894T3 (fr) 2018-04-21
WO2011156324A1 (fr) 2011-12-15
JP6021806B2 (ja) 2016-11-09
EP2579894A1 (fr) 2013-04-17
US20110305711A1 (en) 2011-12-15
UA109658C2 (xx) 2015-09-25
HK1203211A1 (en) 2015-10-23
EA022931B1 (ru) 2016-03-31
IL242409B (en) 2020-07-30
IL222885A0 (en) 2012-12-31
CN102946905B (zh) 2014-10-15
MX340999B (es) 2016-08-03
SI2579894T1 (en) 2018-01-31
ES2930321T3 (es) 2022-12-09
IL222885B (en) 2019-09-26
AU2011265050A1 (en) 2012-11-08
CN102946905A (zh) 2013-02-27
EP3318272B1 (fr) 2022-08-10
JO3330B1 (ar) 2019-03-13
MX363209B (es) 2019-03-14
LUC00112I2 (fr) 2019-12-27
ME02862B (fr) 2018-04-20
EP3318272A1 (fr) 2018-05-09
HUE038135T2 (hu) 2018-09-28
US20170073403A1 (en) 2017-03-16
CN104292332A (zh) 2015-01-21
BR112012031501B1 (pt) 2020-02-11
TWI423818B (zh) 2014-01-21
RS56638B1 (sr) 2018-03-30
TW201210618A (en) 2012-03-16
JP2017014203A (ja) 2017-01-19
EA201270769A1 (ru) 2013-04-30
ZA201208996B (en) 2014-05-28
PL2579894T3 (pl) 2018-04-30
KR101489566B1 (ko) 2015-02-03
AR081434A1 (es) 2012-08-29
CN104292332B (zh) 2019-11-01
NL300979I1 (nl) 2019-04-17
CY2019017I1 (el) 2020-05-29
KR20130034024A (ko) 2013-04-04
NZ603607A (en) 2014-09-26
US9505838B2 (en) 2016-11-29
US20150259415A1 (en) 2015-09-17

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