HUP0203734A2 - Eljárás lizofoszfatidil-etanol-amin előállítására - Google Patents

Eljárás lizofoszfatidil-etanol-amin előállítására

Info

Publication number
HUP0203734A2
HUP0203734A2 HU0203734A HUP0203734A HUP0203734A2 HU P0203734 A2 HUP0203734 A2 HU P0203734A2 HU 0203734 A HU0203734 A HU 0203734A HU P0203734 A HUP0203734 A HU P0203734A HU P0203734 A2 HUP0203734 A2 HU P0203734A2
Authority
HU
Hungary
Prior art keywords
order
mixture containing
lysophosphatidylethanolamine
phospholipid mixture
solvent
Prior art date
Application number
HU0203734A
Other languages
English (en)
Inventor
Guk Hoon Chung
Yong Lae Yang
Original Assignee
Doosan Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Doosan Corporation filed Critical Doosan Corporation
Publication of HUP0203734A2 publication Critical patent/HUP0203734A2/hu
Publication of HUP0203734A3 publication Critical patent/HUP0203734A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/001Amines; Imines
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats

Abstract

Az ismertetés tárgya eljárás nagy tisztaságú lizofoszfatidil-etanol-amin tisztítására, foszfolipid keverék enzimes kezelésével, melyetoldószeres frakcionálás követ, az oszlop tisztítása nélkül. A jelentalálmány szerinti eljárás tartalmazza a 10-99 tömegszázalékfoszfatidil-etanol-amin-tartalmú foszfolipid-keverék hidrolízisétfoszfolipáz A2-vel, lizofoszfolipid képződése érdekében; és alizofoszfolipid kezelését oldószerkeverékkel, mely tartalmaz vizet ésegy vagy több szerves oldószert, melyet kiválasztanak a kisszénatomszámú alkohol, szénhidrogén és alkil-észter csoportból, aszennyezések, kivéve a lizofoszfatidil-etanol-amin eltávolításaérdekében. Ó
HU0203734A 1999-11-30 2000-11-28 A method for preparing lysophosphatidylethanolamine HUP0203734A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019990053780A KR100331932B1 (ko) 1999-11-30 1999-11-30 리소포스파티딜에탄올아민의 제조방법
PCT/KR2000/001369 WO2001040496A1 (en) 1999-11-30 2000-11-28 A method for preparing lysophosphatidylethanolamine

Publications (2)

Publication Number Publication Date
HUP0203734A2 true HUP0203734A2 (hu) 2003-03-28
HUP0203734A3 HUP0203734A3 (en) 2004-03-01

Family

ID=36314055

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203734A HUP0203734A3 (en) 1999-11-30 2000-11-28 A method for preparing lysophosphatidylethanolamine

Country Status (21)

Country Link
US (1) US6773902B1 (hu)
EP (1) EP1238093B1 (hu)
JP (1) JP4045100B2 (hu)
KR (1) KR100331932B1 (hu)
CN (1) CN1253578C (hu)
AT (1) ATE323777T1 (hu)
AU (1) AU779636B2 (hu)
BR (1) BR0016179A (hu)
CA (1) CA2392998A1 (hu)
CR (1) CR6646A (hu)
CZ (1) CZ20021652A3 (hu)
DE (1) DE60027462D1 (hu)
HU (1) HUP0203734A3 (hu)
IL (1) IL149680A0 (hu)
MX (1) MXPA02005383A (hu)
NO (1) NO20022343L (hu)
NZ (1) NZ519060A (hu)
PL (1) PL355480A1 (hu)
RU (1) RU2002117277A (hu)
WO (1) WO2001040496A1 (hu)
ZA (1) ZA200204281B (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100472297B1 (ko) * 2001-09-27 2005-03-07 주식회사 두산 리소인지질의 수용성 조성물
KR20030084200A (ko) * 2002-04-25 2003-11-01 주식회사 두산 비 유기용매시스템에서의 포스파티딜에탄올아민 및리소포스파티딜에탄올아민의 제조방법 및 그 방법으로제조된 리소포스파티딜에탄올아민을 포함하는 수용성 조성물
KR100454086B1 (ko) * 2002-09-14 2004-10-26 학교법인 한양학원 회수율과 감도를 높인 인지질분해효소 d의 활성확인을위한 지질 추출방법
JP4650746B2 (ja) * 2004-03-18 2011-03-16 ナガセケムテックス株式会社 酵素の除去方法および該方法を用いるリン脂質の塩基転移または加水分解方法
US7189544B2 (en) * 2004-04-09 2007-03-13 Cargill, Incorporated Enzymatic modification of lecithin
US20080207503A1 (en) * 2005-06-22 2008-08-28 Chung Byung-Hong Composition and Treatment Methods for Coronary Artery Disease
KR101028489B1 (ko) * 2005-06-30 2011-04-14 주식회사 두산 리소포스파티딜에탄올아민 또는 레시틴을 함유한 안정한수용성 조성물
JP2009148244A (ja) * 2007-11-29 2009-07-09 Gunma Prefecture リゾホスファチジルエタノールアミンの製造法
CN101302547B (zh) * 2008-06-10 2010-06-02 江南大学 一种磷脂酰月桂醇的酶法制备方法
CN102286559A (zh) * 2011-09-06 2011-12-21 三河汇福粮油集团有限公司 一种制备溶血磷脂的方法及所制备的溶血磷脂
CN103073571A (zh) * 2011-11-29 2013-05-01 江南大学 一种磷脂酰乙醇胺的制备方法
KR101661706B1 (ko) * 2014-06-24 2016-10-04 한국생명공학연구원 미생물로부터 리소포스파티딜에탄올아민 18:1의 생산 방법
CN104262387B (zh) * 2014-09-19 2016-06-29 河南省农科院农副产品加工研究所 一种硅胶柱色谱分离纯化溶血磷脂酰乙醇胺的方法
CN104931618B (zh) * 2015-06-26 2016-10-26 卢航 复杂样品中6种磷脂的多重检测方法
CN106479993A (zh) * 2016-09-26 2017-03-08 南京工业大学 一种磷脂酶d催化磷脂酰胆碱合成磷脂酰乙醇胺的方法
CN109851630B (zh) * 2017-11-30 2021-11-30 江苏曼氏生物科技股份有限公司 一种高含量磷脂酰乙醇胺的制备方法
CN110144369A (zh) * 2019-05-22 2019-08-20 杨利平 一种制备高纯度溶血磷脂酰胆碱的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2731852B2 (ja) * 1988-10-22 1998-03-25 富山化学工業株式会社 リゾホスファチジルコリンの新規な製造法
JPH03123493A (ja) * 1989-10-05 1991-05-27 Nippon Oil & Fats Co Ltd ジアシルグリセロリン脂質の加水分解法
JPH053791A (ja) 1991-06-25 1993-01-14 Mercian Corp リノール酸を唯一の構成脂肪酸とするリゾホスフアチジルコリン及びリゾホスフアチジルエタノールアミンの製造方法
TW362115B (en) * 1992-06-16 1999-06-21 Sankyo Lifetech Co Ltd Novel phospholipase A1, process for its preparation and the use thereof
JP3650168B2 (ja) * 1995-06-20 2005-05-18 株式会社ヤクルト本社 リゾ化リン脂質組成物及びその製造法
US5716814A (en) * 1996-02-02 1998-02-10 Biomolecular Products, Inc. Methods for making lysophosphatidylcholine
JP3853464B2 (ja) * 1997-04-08 2006-12-06 辻製油株式会社 植物性リゾレシチンの製造法
US6268187B1 (en) * 1997-07-24 2001-07-31 Doosan Corporation Process for preparing lysophospholipid using enzyme

Also Published As

Publication number Publication date
BR0016179A (pt) 2002-08-27
KR20010048900A (ko) 2001-06-15
EP1238093A1 (en) 2002-09-11
NZ519060A (en) 2003-11-28
EP1238093B1 (en) 2006-04-19
CZ20021652A3 (cs) 2002-11-13
IL149680A0 (en) 2002-11-10
MXPA02005383A (es) 2004-06-21
HUP0203734A3 (en) 2004-03-01
ATE323777T1 (de) 2006-05-15
AU779636B2 (en) 2005-02-03
DE60027462D1 (de) 2006-05-24
US6773902B1 (en) 2004-08-10
NO20022343L (no) 2002-07-04
JP2003515346A (ja) 2003-05-07
AU2024401A (en) 2001-06-12
JP4045100B2 (ja) 2008-02-13
CN1402794A (zh) 2003-03-12
CR6646A (es) 2004-08-16
PL355480A1 (en) 2004-05-04
CN1253578C (zh) 2006-04-26
RU2002117277A (ru) 2004-02-10
NO20022343D0 (no) 2002-05-16
KR100331932B1 (ko) 2002-04-09
WO2001040496A1 (en) 2001-06-07
ZA200204281B (en) 2003-04-30
CA2392998A1 (en) 2001-06-07

Similar Documents

Publication Publication Date Title
HUP0203734A2 (hu) Eljárás lizofoszfatidil-etanol-amin előállítására
MX9702204A (es) Tratamiento con ribozimas de enfermedades o condiciones relacionadas con niveles de lipoproteina (a) [lp(a)] en plasma, inhibiendo apolipoproteina (a) [apo(a)].
DE59608148D1 (de) Verfahren zur herstellung von enantiomerenreinen tropasäureestern
DE1303336T1 (de) Verfahren und apparatur zur isolierung reiner oder grösstenteils reiner organometallverbindungen
DE59810751D1 (de) Verfahren zur Herstellung von 1-Amino-4-(hydroxymethyl)-2-cyclopenten
ATE318255T1 (de) Verfahren zur herstellung von estern
ATE543793T1 (de) Verfahren zur herstellung von benzoesäureestern
ATE299849T1 (de) Verfahren zur herstellung von octafluoropropan
EP1525044B8 (en) Method of purifying air, apparatus for purifying air and building provided with this apparatus
SE9603304D0 (sv) Process for purifying a compound
Kim et al. Silanediol peptidomimetics. Evaluation of four diastereomeric ACE inhibitors
ATE160351T1 (de) Verfahren zur herstellung von 7-trialkylsilyl baccatin iii
MX9301754A (es) Proceso para hidrolizar estereoespecificamente una mezcla de isomeros (+) y (-) de un compuesto.
DE69911430D1 (de) Verfahren zur herstellung von 1-(1h)-benzoquinolizin-3-on derivaten
Rytczak et al. The chemical synthesis and cytotoxicity of new sulfur analogues of 2-methoxy-lysophosphatidylcholine
HUP0303106A2 (hu) Eljárás pravasztatin tisztítására
DE50206754D1 (de) Verfahren zur herstellung von hochreinem triethylendiamin
MY136397A (en) Recovery of palm phytonutrients
DE60133395D1 (de) Verfahren zur herstellung von alpha'-chlorketonen
ATE236925T1 (de) Verfahren zur reinigung von apolipoproteinen
ATE395428T1 (de) Verfahren zur isolierung und reinigung von lipidezellwandkomponenten
BRPI0418481A (pt) método para a produção de ácido (met)acrìlico
ATE213493T1 (de) Verfahren zur herstellung von methoximinophenylglyoxylsäure-derivaten
PT1981836E (pt) Processo para a purificação de ésteres alquílicos de ácidos gordos e utilização de agentes para facilitar tal purificação
DE60327813D1 (de) Verfahren zu herstellung von lovastatin.