ATE395428T1 - Verfahren zur isolierung und reinigung von lipidezellwandkomponenten - Google Patents

Verfahren zur isolierung und reinigung von lipidezellwandkomponenten

Info

Publication number
ATE395428T1
ATE395428T1 AT96903143T AT96903143T ATE395428T1 AT E395428 T1 ATE395428 T1 AT E395428T1 AT 96903143 T AT96903143 T AT 96903143T AT 96903143 T AT96903143 T AT 96903143T AT E395428 T1 ATE395428 T1 AT E395428T1
Authority
AT
Austria
Prior art keywords
derivatives
salts
mycolic acids
lipide
isolation
Prior art date
Application number
AT96903143T
Other languages
English (en)
Inventor
Jan Verschoor
Original Assignee
Adcock Ingram Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adcock Ingram Ltd filed Critical Adcock Ingram Ltd
Application granted granted Critical
Publication of ATE395428T1 publication Critical patent/ATE395428T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
AT96903143T 1995-02-22 1996-02-22 Verfahren zur isolierung und reinigung von lipidezellwandkomponenten ATE395428T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ZA951464 1995-02-22

Publications (1)

Publication Number Publication Date
ATE395428T1 true ATE395428T1 (de) 2008-05-15

Family

ID=25584852

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96903143T ATE395428T1 (de) 1995-02-22 1996-02-22 Verfahren zur isolierung und reinigung von lipidezellwandkomponenten

Country Status (12)

Country Link
US (1) US6171830B1 (de)
EP (1) EP0811075B1 (de)
JP (1) JPH11500906A (de)
CN (1) CN1183811A (de)
AT (1) ATE395428T1 (de)
AU (1) AU720288B2 (de)
CA (1) CA2213428A1 (de)
DE (1) DE69637522D1 (de)
HU (1) HUP9900378A3 (de)
RU (1) RU2155230C2 (de)
WO (1) WO1996026288A1 (de)
ZA (1) ZA961412B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO359396A0 (en) * 1996-11-13 1996-12-05 Amrad Operations Pty. Limited A method of treatment and pharmaceutical compositions useful for same
AU726734B2 (en) * 1996-11-13 2000-11-16 Centenary Institute Of Cancer Medicine & Cell Biology Mycobacterium cell wall compositions
CN1057077C (zh) * 1998-05-12 2000-10-04 中国医学科学院医药生物技术研究所 一种具有免疫抑制作用的化合物
CA3211104A1 (en) * 2010-02-23 2011-09-01 University Of Washington Artificial mycolic acid membranes
US9877917B2 (en) 2011-01-04 2018-01-30 Archivel Farma, S.L. Liposome formulation suitable for treating or preventing tuberculosis
CN104411326B (zh) 2012-01-12 2018-02-02 阿尔西维尔法尔玛公司 抗哮喘的mtb‑c疫苗

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4877612A (en) * 1985-05-20 1989-10-31 Frank M. Berger Immunological adjuvant and process for preparing the same, pharmaceutical compositions, and process
EP0261248B1 (de) * 1986-03-20 1991-05-29 Sawai Pharmaceutical Co., Ltd. -g(a), -g(a)-trehalose trimycolat und arzneimittelzubereitung
DE69433115T2 (de) * 1993-06-21 2004-04-01 Brigham And Women's Hospital, Boston Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien
CA2187779A1 (en) * 1994-04-14 1995-10-26 Jan Adrianus Verschoor A method for detecting the presence of a mycobacterium species and a kit and antibodies for use therein

Also Published As

Publication number Publication date
HUP9900378A3 (en) 1999-11-29
DE69637522D1 (de) 2008-06-26
CN1183811A (zh) 1998-06-03
JPH11500906A (ja) 1999-01-26
ZA961412B (en) 1996-08-26
US6171830B1 (en) 2001-01-09
AU4728796A (en) 1996-09-11
HUP9900378A2 (hu) 1999-05-28
AU720288B2 (en) 2000-05-25
RU2155230C2 (ru) 2000-08-27
EP0811075B1 (de) 2008-05-14
WO1996026288A1 (en) 1996-08-29
EP0811075A1 (de) 1997-12-10
CA2213428A1 (en) 1996-08-29

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Legal Events

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