DE68928249D1 - Verfahren zur Trennung von Methylester von alpha-L-aspartyl-L-phenylalaninen - Google Patents

Verfahren zur Trennung von Methylester von alpha-L-aspartyl-L-phenylalaninen

Info

Publication number
DE68928249D1
DE68928249D1 DE68928249T DE68928249T DE68928249D1 DE 68928249 D1 DE68928249 D1 DE 68928249D1 DE 68928249 T DE68928249 T DE 68928249T DE 68928249 T DE68928249 T DE 68928249T DE 68928249 D1 DE68928249 D1 DE 68928249D1
Authority
DE
Germany
Prior art keywords
alpha
aspartyl
methyl ester
phenylalanines
separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68928249T
Other languages
English (en)
Other versions
DE68928249T2 (de
Inventor
Toshio Katoh
Chojiro Higuchi
Takeshi Oura
Masanobu Ajioka
Akihiro Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Publication of DE68928249D1 publication Critical patent/DE68928249D1/de
Application granted granted Critical
Publication of DE68928249T2 publication Critical patent/DE68928249T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
  • Extraction Or Liquid Replacement (AREA)
DE68928249T 1988-03-14 1989-03-09 Verfahren zur Trennung von Methylester von alpha-L-aspartyl-L-phenylalaninen Expired - Fee Related DE68928249T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP5821088 1988-03-14
JP13506088 1988-06-01
JP14367388 1988-06-13
JP15686688 1988-06-27

Publications (2)

Publication Number Publication Date
DE68928249D1 true DE68928249D1 (de) 1997-09-18
DE68928249T2 DE68928249T2 (de) 1998-02-26

Family

ID=27463624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68928249T Expired - Fee Related DE68928249T2 (de) 1988-03-14 1989-03-09 Verfahren zur Trennung von Methylester von alpha-L-aspartyl-L-phenylalaninen

Country Status (11)

Country Link
EP (1) EP0333036B1 (de)
JP (1) JP2662287B2 (de)
KR (1) KR910006286B1 (de)
CN (1) CN1036201C (de)
AT (1) ATE156840T1 (de)
AU (1) AU605683B2 (de)
BR (1) BR8901174A (de)
CA (1) CA1339657C (de)
DE (1) DE68928249T2 (de)
DK (1) DK123089A (de)
NO (1) NO891069L (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015032A1 (en) * 1997-09-24 1999-04-01 Holland Sweetener Company V.O.F. Sweetening composition comprising aspartame and 2,4-dihydroxybenzoic acid
US7297813B2 (en) 2004-08-05 2007-11-20 Arkema Inc. Removal of alkyl alkanesulfonate esters from alkanesulfonic acids and other organic media
JP6564539B1 (ja) * 2018-09-14 2019-08-21 長瀬産業株式会社 スルホン酸化合物によるペプチド精製方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5113737A (en) * 1974-07-23 1976-02-03 Ajinomoto Kk Arufua ll asuparuchiru ll fueniruaraninteikyuarukiruesuteruno seizoho
IE810577L (en) * 1983-05-31 1982-09-16 Prendergast Angela Apparatus for fermentation
US4439460A (en) * 1982-06-01 1984-03-27 G. D. Searle & Co. Dipeptide sweetener sulfate and sulfonate salts
GB2140805B (en) * 1983-05-31 1986-08-13 Erba Farmitalia Isolation of aspartame
GB8321802D0 (en) * 1983-08-12 1983-09-14 Erba Farmitalia Aspartame synthesis

Also Published As

Publication number Publication date
CN1036201C (zh) 1997-10-22
ATE156840T1 (de) 1997-08-15
AU3127789A (en) 1989-09-14
KR890014575A (ko) 1989-10-24
JP2662287B2 (ja) 1997-10-08
AU605683B2 (en) 1991-01-17
CN1036580A (zh) 1989-10-25
BR8901174A (pt) 1989-10-31
DE68928249T2 (de) 1998-02-26
KR910006286B1 (ko) 1991-08-19
EP0333036B1 (de) 1997-08-13
JPH0285295A (ja) 1990-03-26
NO891069D0 (no) 1989-03-13
CA1339657C (en) 1998-02-03
EP0333036A3 (de) 1991-05-08
EP0333036A2 (de) 1989-09-20
NO891069L (no) 1989-09-15
DK123089D0 (da) 1989-03-14
DK123089A (da) 1989-09-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MITSUI CHEMICALS, INC., TOKIO/TOKYO, JP

8339 Ceased/non-payment of the annual fee