ES2061918T3 - Procedimiento para la purificacion de 1,2-bis (nicotinamido) propano. - Google Patents
Procedimiento para la purificacion de 1,2-bis (nicotinamido) propano.Info
- Publication number
- ES2061918T3 ES2061918T3 ES89123739T ES89123739T ES2061918T3 ES 2061918 T3 ES2061918 T3 ES 2061918T3 ES 89123739 T ES89123739 T ES 89123739T ES 89123739 T ES89123739 T ES 89123739T ES 2061918 T3 ES2061918 T3 ES 2061918T3
- Authority
- ES
- Spain
- Prior art keywords
- bis
- propane
- nicotinamido
- crude
- nicotinamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
UN NUEVO PROCESO PARA PURIFICAR 1,2-BIS(NICOTINAMIDO)PROPANO CRUDO OBTENIDO POR LA REACCION DEL ACIDO NICOTINICO CON 1,2-PROPANODIAMINA. ESTE PROCESO COMPRENDE LA FIRMACION DEL 1,2-BIS(NICOTINAMIDO)PROPANO DINITRATO A PARTIR DEL 1,2-BIS(NICOTINAMIDO)PROPANO CRUDO, SUSPENDIENDO EL DINITRATO EN UN SOLVENTE ORGANICO, AÑADIENDO UN ALCALI O UNA SOLUCION ALCALINA A LA SUSPENSION PARA DISOCIAR EL 1,2-BIS(NICOTINAMIDO)PROPANO LIBRE, EXTRAYENDOLO DE LA SUSPENSION CON UN SOLVENTE, Y ELIMINANDO EL SOLVENTE PARA AISLAR EL PRODUCTO PURIFICADO. DE ACUERDO CON ESTE PROCESO, EL 1,2-BIS(NICOTINAMIDO)PROPANO CRUDO PUEDE SER PURIFICADO EFICIENTEMENTE PARA DAR AL PRODUCTO UNA GRAN PUREZA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP33025588 | 1988-12-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2061918T3 true ES2061918T3 (es) | 1994-12-16 |
Family
ID=18230595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89123739T Expired - Lifetime ES2061918T3 (es) | 1988-12-27 | 1989-12-22 | Procedimiento para la purificacion de 1,2-bis (nicotinamido) propano. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5099022A (es) |
EP (1) | EP0376185B1 (es) |
AT (1) | ATE110058T1 (es) |
CA (1) | CA2006665C (es) |
DE (1) | DE68917574T2 (es) |
ES (1) | ES2061918T3 (es) |
HK (1) | HK1005027A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09315972A (ja) * | 1996-03-22 | 1997-12-09 | Chugai Pharmaceut Co Ltd | 脊髄損傷治療剤 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2681341A (en) * | 1952-08-19 | 1954-06-15 | S E Massengill Company | Solid acid salts of nu, nu-diethyl pyridine-3-carboxylic acid amide |
JPS5675474A (en) * | 1979-11-22 | 1981-06-22 | Chugai Pharmaceut Co Ltd | Nicotinamide derivative and medicine containing the same |
US4910301A (en) * | 1985-08-05 | 1990-03-20 | Bristol-Myers Company | Cefepime cephalosporin salts |
-
1989
- 1989-12-22 EP EP89123739A patent/EP0376185B1/en not_active Expired - Lifetime
- 1989-12-22 DE DE68917574T patent/DE68917574T2/de not_active Expired - Fee Related
- 1989-12-22 ES ES89123739T patent/ES2061918T3/es not_active Expired - Lifetime
- 1989-12-22 AT AT89123739T patent/ATE110058T1/de not_active IP Right Cessation
- 1989-12-27 US US07/456,794 patent/US5099022A/en not_active Expired - Lifetime
- 1989-12-27 CA CA002006665A patent/CA2006665C/en not_active Expired - Fee Related
-
1998
- 1998-05-14 HK HK98104189A patent/HK1005027A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5099022A (en) | 1992-03-24 |
CA2006665A1 (en) | 1990-06-27 |
DE68917574T2 (de) | 1994-12-15 |
EP0376185A2 (en) | 1990-07-04 |
HK1005027A1 (en) | 1998-12-18 |
DE68917574D1 (de) | 1994-09-22 |
CA2006665C (en) | 1998-02-17 |
ATE110058T1 (de) | 1994-09-15 |
EP0376185A3 (en) | 1991-03-27 |
EP0376185B1 (en) | 1994-08-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9407655A (pt) | Método para a produçao de steres cíclicos T | |
DE69021455D1 (de) | Verfahren zur Herstellung von Ascorbinsäure. | |
DE3583043D1 (de) | Verfahren zur reinigung von podophyllotoxin. | |
HUP9900110A2 (hu) | Új eljárás omeprazol szintézisére | |
AU582680B2 (en) | Purification of glycolide | |
ATE106380T1 (de) | Verfahren zur herstellung und rückgewinnung von oxydiphthalsäureanhydriden. | |
ES2074431T3 (es) | Un procedimiento para la sintesis de amicacina. | |
ATE73850T1 (de) | Verfahren zur herstellung von 2-keto-dglukars|ure. | |
PL235019A1 (es) | ||
DK0527537T3 (da) | Metalfjernelse fra vandige peroxysyrer eller peroxysalte | |
ES2061918T3 (es) | Procedimiento para la purificacion de 1,2-bis (nicotinamido) propano. | |
EP0306614A3 (en) | Improvements of processes and plants for the production of urea | |
BR8901174A (pt) | Processo para a separacao de ester metilico de alfa-l-aspartil-l-fenilalanina | |
ES2026886T3 (es) | Procedimiento para la recuperacion de piridina o de metilpiridinas o sus mezclas a partir de mezclas de reaccion que contienen butanodicarboxilatos de metilo. | |
ES2041855T3 (es) | Procedimiento para separar hierro, cromo y vanadio de acido fosforico. | |
JPS6450855A (en) | Purification of 4,4'-dihydroxydiphenylsulfone | |
JPS5564569A (en) | Purification of thioglycolic acid | |
RO100043B1 (ro) | Procedeu de preparare si purificare a 2-nitro-5-feniltiometoxiacetanilidei |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 376185 Country of ref document: ES |