ATE160351T1 - Verfahren zur herstellung von 7-trialkylsilyl baccatin iii - Google Patents

Verfahren zur herstellung von 7-trialkylsilyl baccatin iii

Info

Publication number
ATE160351T1
ATE160351T1 AT95916696T AT95916696T ATE160351T1 AT E160351 T1 ATE160351 T1 AT E160351T1 AT 95916696 T AT95916696 T AT 95916696T AT 95916696 T AT95916696 T AT 95916696T AT E160351 T1 ATE160351 T1 AT E160351T1
Authority
AT
Austria
Prior art keywords
pct
symbols
date oct
producing
sec
Prior art date
Application number
AT95916696T
Other languages
English (en)
Inventor
Jean-Pierre Bastart
Jean-Pierre Leconte
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of ATE160351T1 publication Critical patent/ATE160351T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Silicon Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Silicon Polymers (AREA)
  • Internal Circuitry In Semiconductor Integrated Circuit Devices (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
AT95916696T 1994-04-05 1995-04-03 Verfahren zur herstellung von 7-trialkylsilyl baccatin iii ATE160351T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9403979A FR2718137B1 (fr) 1994-04-05 1994-04-05 Procédé de préparation de trialcoylsilyl-7 baccatine III.

Publications (1)

Publication Number Publication Date
ATE160351T1 true ATE160351T1 (de) 1997-12-15

Family

ID=9461745

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95916696T ATE160351T1 (de) 1994-04-05 1995-04-03 Verfahren zur herstellung von 7-trialkylsilyl baccatin iii

Country Status (33)

Country Link
US (1) US5670658A (de)
EP (1) EP0754185B1 (de)
JP (1) JP3718225B2 (de)
KR (1) KR100399246B1 (de)
CN (1) CN1058497C (de)
AT (1) ATE160351T1 (de)
AU (1) AU683560B2 (de)
BG (1) BG62735B1 (de)
BR (1) BR9507444A (de)
CA (1) CA2186916C (de)
CZ (1) CZ288397B6 (de)
DE (1) DE69501080T2 (de)
DK (1) DK0754185T3 (de)
EE (1) EE03240B1 (de)
ES (1) ES2109103T3 (de)
FI (1) FI115970B (de)
FR (1) FR2718137B1 (de)
GE (1) GEP19991537B (de)
GR (1) GR3025448T3 (de)
HU (1) HU214158B (de)
LT (1) LT4185B (de)
LV (1) LV11691B (de)
MX (1) MX9604466A (de)
NO (1) NO305839B1 (de)
NZ (1) NZ284490A (de)
PL (1) PL316588A1 (de)
RO (1) RO115631B1 (de)
RU (1) RU2127729C1 (de)
SK (1) SK280448B6 (de)
TW (1) TW284765B (de)
UA (1) UA44730C2 (de)
WO (1) WO1995026967A1 (de)
ZA (1) ZA952733B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5973160A (en) * 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
US7288665B1 (en) 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
ATE234800T1 (de) 1997-08-21 2003-04-15 Univ Florida State Verfahren zur synthese von taxanen
CZ2003837A3 (cs) 2000-09-22 2004-12-15 Bristol-Myers Squibb Company Způsob pro snížení toxicity při kombinovaných chemoterapiích
US20040132991A1 (en) * 2002-10-09 2004-07-08 Phytogen Life Sciences Inc. Novel taxanes and methods related to use and preparation thereof
US7202370B2 (en) * 2003-10-27 2007-04-10 Conor Medsystems, Inc. Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
EP1747209A4 (de) * 2004-05-14 2007-12-12 Immunogen Inc Einfaches verfahren zur synthese von baccatin-iii-verbindungen
CZ298333B6 (cs) * 2005-09-26 2007-08-29 Zentiva, A. S Zpusob prípravy 7-trialkylsilylbaccatinu III
MX2011001583A (es) 2008-08-11 2011-04-04 Nektar Therapeutics Conjugados de alcanoato polimericos de multiples brazos.
WO2012088422A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
US10894087B2 (en) 2010-12-22 2021-01-19 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
WO2012088391A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Non-ring hydroxy substituted taxanes and methods for synthesizing the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4823167A (en) * 1986-12-16 1989-04-18 Baxter International Inc. Catheter calibration device
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides
US5597931A (en) * 1992-03-30 1997-01-28 Sloan-Kettering Institute For Cancer Research Total synthesis of taxol and analogues thereof
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
US5405972A (en) * 1993-07-20 1995-04-11 Florida State University Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
US5449790A (en) * 1994-04-06 1995-09-12 Hauser Chemical Research, Inc. Preparation of 10-deacetylbaccatin III and 7-protected-10-deacetylbaccatin III derivatives from 10-deacetyl taxol A, 10-deacetyl taxol B, and 10-deacetyl taxol C

Also Published As

Publication number Publication date
FI964001A (fi) 1996-10-04
CN1058497C (zh) 2000-11-15
NO305839B1 (no) 1999-08-02
US5670658A (en) 1997-09-23
LT96137A (en) 1997-02-25
HU214158B (hu) 1998-01-28
GEP19991537B (en) 1999-03-05
CZ290096A3 (en) 1997-01-15
LV11691B (en) 1997-06-20
RO115631B1 (ro) 2000-04-28
UA44730C2 (uk) 2002-03-15
NO964103L (no) 1996-09-27
CZ288397B6 (en) 2001-06-13
CA2186916A1 (fr) 1995-10-12
MX9604466A (es) 1997-07-31
DK0754185T3 (da) 1998-01-26
GR3025448T3 (en) 1998-02-27
JP3718225B2 (ja) 2005-11-24
BG100886A (en) 1998-01-30
FR2718137B1 (fr) 1996-04-26
EP0754185B1 (de) 1997-11-19
DE69501080T2 (de) 1998-04-02
CN1145073A (zh) 1997-03-12
BR9507444A (pt) 1997-09-16
EE03240B1 (et) 1999-12-15
NO964103D0 (no) 1996-09-27
LT4185B (en) 1997-07-25
HU9602735D0 (en) 1996-11-28
FI115970B (fi) 2005-08-31
AU2309695A (en) 1995-10-23
WO1995026967A1 (fr) 1995-10-12
SK280448B6 (sk) 2000-02-14
HUT76035A (en) 1997-06-30
SK126596A3 (en) 1997-04-09
NZ284490A (en) 1998-08-26
FI964001A0 (fi) 1996-10-04
LV11691A (lv) 1997-02-20
RU2127729C1 (ru) 1999-03-20
TW284765B (de) 1996-09-01
ZA952733B (en) 1996-01-09
DE69501080D1 (de) 1998-01-02
CA2186916C (fr) 2004-05-25
EP0754185A1 (de) 1997-01-22
AU683560B2 (en) 1997-11-13
ES2109103T3 (es) 1998-01-01
BG62735B1 (bg) 2000-06-30
FR2718137A1 (fr) 1995-10-06
JPH09512522A (ja) 1997-12-16
KR100399246B1 (ko) 2004-02-11
PL316588A1 (en) 1997-01-20

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Legal Events

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UEP Publication of translation of european patent specification
EEFA Change of the company name