ES2109103T3 - Procedimiento para la preparacion de trialquilsilil-7 bacatina iii. - Google Patents

Procedimiento para la preparacion de trialquilsilil-7 bacatina iii.

Info

Publication number
ES2109103T3
ES2109103T3 ES95916696T ES95916696T ES2109103T3 ES 2109103 T3 ES2109103 T3 ES 2109103T3 ES 95916696 T ES95916696 T ES 95916696T ES 95916696 T ES95916696 T ES 95916696T ES 2109103 T3 ES2109103 T3 ES 2109103T3
Authority
ES
Spain
Prior art keywords
pct
iii
symbols
preparation
date oct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95916696T
Other languages
English (en)
Inventor
Jean-Pierre Bastart
Jean-Pierre Leconte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Application granted granted Critical
Publication of ES2109103T3 publication Critical patent/ES2109103T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Saccharide Compounds (AREA)
  • Silicon Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Silicon Polymers (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Internal Circuitry In Semiconductor Integrated Circuit Devices (AREA)
  • Steroid Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE LA TRIALCOILSILIL-7 BACATINA III A PARTIR DE LA DESACETIL-10 BACATINA III.
ES95916696T 1994-04-05 1995-04-03 Procedimiento para la preparacion de trialquilsilil-7 bacatina iii. Expired - Lifetime ES2109103T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9403979A FR2718137B1 (fr) 1994-04-05 1994-04-05 Procédé de préparation de trialcoylsilyl-7 baccatine III.

Publications (1)

Publication Number Publication Date
ES2109103T3 true ES2109103T3 (es) 1998-01-01

Family

ID=9461745

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95916696T Expired - Lifetime ES2109103T3 (es) 1994-04-05 1995-04-03 Procedimiento para la preparacion de trialquilsilil-7 bacatina iii.

Country Status (33)

Country Link
US (1) US5670658A (es)
EP (1) EP0754185B1 (es)
JP (1) JP3718225B2 (es)
KR (1) KR100399246B1 (es)
CN (1) CN1058497C (es)
AT (1) ATE160351T1 (es)
AU (1) AU683560B2 (es)
BG (1) BG62735B1 (es)
BR (1) BR9507444A (es)
CA (1) CA2186916C (es)
CZ (1) CZ288397B6 (es)
DE (1) DE69501080T2 (es)
DK (1) DK0754185T3 (es)
EE (1) EE03240B1 (es)
ES (1) ES2109103T3 (es)
FI (1) FI115970B (es)
FR (1) FR2718137B1 (es)
GE (1) GEP19991537B (es)
GR (1) GR3025448T3 (es)
HU (1) HU214158B (es)
LT (1) LT4185B (es)
LV (1) LV11691B (es)
MX (1) MX9604466A (es)
NO (1) NO305839B1 (es)
NZ (1) NZ284490A (es)
PL (1) PL316588A1 (es)
RO (1) RO115631B1 (es)
RU (1) RU2127729C1 (es)
SK (1) SK280448B6 (es)
TW (1) TW284765B (es)
UA (1) UA44730C2 (es)
WO (1) WO1995026967A1 (es)
ZA (1) ZA952733B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5973160A (en) * 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
US7288665B1 (en) 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
RU2219161C2 (ru) 1997-08-21 2003-12-20 Флорида Стейт Юниверсити Способ синтеза таксанов
CA2422964A1 (en) 2000-09-22 2002-03-28 Bristol Myers Squibb Company Method for reducing toxicity of combined chemotherapies
EP1562927B1 (en) * 2002-10-09 2009-05-13 Chatham Biotec Ltd. Thio-analogues of paclitaxel and intermediates thereof
US7202370B2 (en) * 2003-10-27 2007-04-10 Conor Medsystems, Inc. Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
BRPI0511109A (pt) * 2004-05-14 2007-11-27 Immunogen Inc método fácil para sintetizar compostos de baccatin iii
CZ298333B6 (cs) * 2005-09-26 2007-08-29 Zentiva, A. S Zpusob prípravy 7-trialkylsilylbaccatinu III
EP2331140B1 (en) 2008-08-11 2018-07-04 Nektar Therapeutics Multi-arm polymeric alkanoate conjugates
WO2012088391A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Non-ring hydroxy substituted taxanes and methods for synthesizing the same
WO2012088422A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
WO2012088445A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4823167A (en) * 1986-12-16 1989-04-18 Baxter International Inc. Catheter calibration device
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides
US5597931A (en) * 1992-03-30 1997-01-28 Sloan-Kettering Institute For Cancer Research Total synthesis of taxol and analogues thereof
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
US5405972A (en) * 1993-07-20 1995-04-11 Florida State University Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
US5449790A (en) * 1994-04-06 1995-09-12 Hauser Chemical Research, Inc. Preparation of 10-deacetylbaccatin III and 7-protected-10-deacetylbaccatin III derivatives from 10-deacetyl taxol A, 10-deacetyl taxol B, and 10-deacetyl taxol C

Also Published As

Publication number Publication date
US5670658A (en) 1997-09-23
KR100399246B1 (ko) 2004-02-11
TW284765B (es) 1996-09-01
HU9602735D0 (en) 1996-11-28
GEP19991537B (en) 1999-03-05
EP0754185A1 (fr) 1997-01-22
SK126596A3 (en) 1997-04-09
AU683560B2 (en) 1997-11-13
LV11691B (en) 1997-06-20
FI964001A0 (fi) 1996-10-04
CZ290096A3 (en) 1997-01-15
LT96137A (en) 1997-02-25
FI964001A (fi) 1996-10-04
HU214158B (hu) 1998-01-28
RU2127729C1 (ru) 1999-03-20
PL316588A1 (en) 1997-01-20
FI115970B (fi) 2005-08-31
ZA952733B (en) 1996-01-09
AU2309695A (en) 1995-10-23
HUT76035A (en) 1997-06-30
NO964103D0 (no) 1996-09-27
WO1995026967A1 (fr) 1995-10-12
NO305839B1 (no) 1999-08-02
NO964103L (no) 1996-09-27
BG62735B1 (bg) 2000-06-30
JP3718225B2 (ja) 2005-11-24
CA2186916C (fr) 2004-05-25
NZ284490A (en) 1998-08-26
CZ288397B6 (en) 2001-06-13
EE03240B1 (et) 1999-12-15
GR3025448T3 (en) 1998-02-27
LT4185B (en) 1997-07-25
EP0754185B1 (fr) 1997-11-19
CN1145073A (zh) 1997-03-12
FR2718137A1 (fr) 1995-10-06
CA2186916A1 (fr) 1995-10-12
DE69501080T2 (de) 1998-04-02
SK280448B6 (sk) 2000-02-14
MX9604466A (es) 1997-07-31
UA44730C2 (uk) 2002-03-15
DK0754185T3 (da) 1998-01-26
DE69501080D1 (de) 1998-01-02
JPH09512522A (ja) 1997-12-16
BG100886A (en) 1998-01-30
RO115631B1 (ro) 2000-04-28
ATE160351T1 (de) 1997-12-15
BR9507444A (pt) 1997-09-16
LV11691A (lv) 1997-02-20
CN1058497C (zh) 2000-11-15
FR2718137B1 (fr) 1996-04-26

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