HUP0104258A2 - HMG-CoA reduktáz inhibítort tartalmazó stabil gyógyszerkészítmények - Google Patents

HMG-CoA reduktáz inhibítort tartalmazó stabil gyógyszerkészítmények

Info

Publication number
HUP0104258A2
HUP0104258A2 HU0104258A HUP0104258A HUP0104258A2 HU P0104258 A2 HUP0104258 A2 HU P0104258A2 HU 0104258 A HU0104258 A HU 0104258A HU P0104258 A HUP0104258 A HU P0104258A HU P0104258 A2 HUP0104258 A2 HU P0104258A2
Authority
HU
Hungary
Prior art keywords
hmg
coa reductase
reductase inhibitor
stable pharmaceutical
pharmaceutical formulation
Prior art date
Application number
HU0104258A
Other languages
English (en)
Inventor
Janez Kerc
Original Assignee
Lek Pharmaceutical And Chemical Company D.D.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceutical And Chemical Company D.D. filed Critical Lek Pharmaceutical And Chemical Company D.D.
Publication of HUP0104258A2 publication Critical patent/HUP0104258A2/hu
Publication of HUP0104258A3 publication Critical patent/HUP0104258A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)

Abstract

A találmány tárgya magas vérkoleszterinszint és magas vérzsírszintkezelésére alkalmas szilárd, stabil gyógyszerkészítmény, amelyhatóanyagként olyan HMG-CoA-reduktáz-inhibitort tartalmaz, amelyönmagában 7 és 11 közötti pH-értéket biztosít. Ó
HU0104258A 1998-12-16 1999-10-29 Stable pharmaceutical formulation comprising a hmg-coa reductase inhibitor HUP0104258A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI9800309A SI20109A (sl) 1998-12-16 1998-12-16 Stabilna farmacevtska formulacija
PCT/IB1999/001749 WO2000035425A1 (en) 1998-12-16 1999-10-29 STABLE PHARMACEUTICAL FORMULATION COMPRISING A HMG-CoA REDUCTASE INHIBITOR

Publications (2)

Publication Number Publication Date
HUP0104258A2 true HUP0104258A2 (hu) 2002-03-28
HUP0104258A3 HUP0104258A3 (en) 2002-11-28

Family

ID=20432372

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104258A HUP0104258A3 (en) 1998-12-16 1999-10-29 Stable pharmaceutical formulation comprising a hmg-coa reductase inhibitor

Country Status (25)

Country Link
US (3) US6680341B1 (hu)
EP (2) EP1911445A3 (hu)
JP (1) JP2002532409A (hu)
KR (1) KR100638307B1 (hu)
CN (1) CN1198597C (hu)
AT (1) ATE380020T1 (hu)
AU (1) AU775946B2 (hu)
BG (1) BG105559A (hu)
CA (1) CA2348988C (hu)
CZ (1) CZ302562B6 (hu)
DE (1) DE69937691T2 (hu)
ES (1) ES2299265T3 (hu)
HR (1) HRP20010325A2 (hu)
HU (1) HUP0104258A3 (hu)
IL (2) IL143759A0 (hu)
IS (1) IS5939A (hu)
NZ (1) NZ511260A (hu)
PL (1) PL347686A1 (hu)
RU (1) RU2227019C2 (hu)
SI (2) SI20109A (hu)
SK (1) SK8092001A3 (hu)
TR (1) TR200101235T2 (hu)
WO (1) WO2000035425A1 (hu)
YU (1) YU35501A (hu)
ZA (1) ZA200103802B (hu)

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EP1296672B2 (en) † 2000-06-09 2018-10-24 LEK Pharmaceuticals d.d. Stable pharmaceutical product and formulation
US6806290B2 (en) 2000-06-09 2004-10-19 Lek Pharmaceuticals D.D. Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same
EP1292293B1 (en) 2000-06-09 2004-02-25 Lek Pharmaceutical and Chemical Co. D.D. Stabilized pharmaceutically effective composition and pharmaceutical formulation comprising the same
US20050215636A1 (en) * 2000-10-05 2005-09-29 Vilmos Keri Pravastatin sodium substantially free of pravastatin lactone and EPI-pravastatin, and compositions containing same
SI20848A (sl) * 2001-03-14 2002-10-31 Lek, Tovarna Farmacevtskih In Kemijskih Izdelkov, D.D. Farmacevtska formulacija, ki vsebuje atorvastatin kalcij
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US8163797B2 (en) * 2003-12-31 2012-04-24 Actavis Elizabeth Llc Method of treating with stable pravastatin formulation
WO2005084669A1 (en) * 2004-03-01 2005-09-15 Lek Pharmaceuticals D.D. Pharmaceutical composition
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WO2008062476A2 (en) * 2006-10-31 2008-05-29 Glenmark Pharmaceutical Limited Pharmaceutical composition comprising rosuvastatin or pharmaceutically accepatble salts thereof
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JPWO2011049122A1 (ja) * 2009-10-21 2013-03-14 第一三共株式会社 プラバスタチンナトリウム口腔内速崩壊錠及びその製造方法
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Also Published As

Publication number Publication date
CN1330538A (zh) 2002-01-09
SI1148872T1 (sl) 2008-04-30
EP1911445A3 (en) 2011-04-27
IL143759A0 (en) 2002-04-21
HUP0104258A3 (en) 2002-11-28
JP2002532409A (ja) 2002-10-02
US6680341B1 (en) 2004-01-20
IS5939A (is) 2001-05-15
ATE380020T1 (de) 2007-12-15
CZ20011727A3 (cs) 2001-09-12
IL143759A (en) 2006-08-01
ES2299265T3 (es) 2008-05-16
AU6360899A (en) 2000-07-03
CA2348988C (en) 2009-07-21
BG105559A (en) 2001-12-29
US20040072894A1 (en) 2004-04-15
CA2348988A1 (en) 2000-06-22
WO2000035425A1 (en) 2000-06-22
HRP20010325A2 (en) 2002-06-30
TR200101235T2 (tr) 2001-10-22
CN1198597C (zh) 2005-04-27
DE69937691D1 (de) 2008-01-17
AU775946B2 (en) 2004-08-19
KR20010101105A (ko) 2001-11-14
CZ302562B6 (cs) 2011-07-13
ZA200103802B (en) 2002-06-10
DE69937691T2 (de) 2008-11-20
SK8092001A3 (en) 2001-10-08
NZ511260A (en) 2004-01-30
EP1148872A1 (en) 2001-10-31
EP1148872B1 (en) 2007-12-05
US20090264497A1 (en) 2009-10-22
PL347686A1 (en) 2002-04-22
SI20109A (sl) 2000-06-30
KR100638307B1 (ko) 2006-10-25
EP1911445A2 (en) 2008-04-16
RU2227019C2 (ru) 2004-04-20
YU35501A (sh) 2005-07-19

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees