AU2002250977A1 - Combination of active ingredients consisting of the racemate of tramadol and of (+)-o-desmethyltramadol - Google Patents

Combination of active ingredients consisting of the racemate of tramadol and of (+)-o-desmethyltramadol

Info

Publication number
AU2002250977A1
AU2002250977A1 AU2002250977A AU2002250977A AU2002250977A1 AU 2002250977 A1 AU2002250977 A1 AU 2002250977A1 AU 2002250977 A AU2002250977 A AU 2002250977A AU 2002250977 A AU2002250977 A AU 2002250977A AU 2002250977 A1 AU2002250977 A1 AU 2002250977A1
Authority
AU
Australia
Prior art keywords
desmethyltramadol
tramadol
racemate
combination
active ingredients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002250977A
Inventor
Johannes Bartholomaus
Elmar Friderichs
Stephan Wnendt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of AU2002250977A1 publication Critical patent/AU2002250977A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AU2002250977A 2001-02-21 2002-02-20 Combination of active ingredients consisting of the racemate of tramadol and of (+)-o-desmethyltramadol Abandoned AU2002250977A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10108123A DE10108123A1 (en) 2001-02-21 2001-02-21 drug combination
DE10108123.5 2001-02-21
PCT/EP2002/001762 WO2002066025A2 (en) 2001-02-21 2002-02-20 Combination of active ingredients consisting of the racemate of tramadol and of (+)-o-desmethyltramadol

Publications (1)

Publication Number Publication Date
AU2002250977A1 true AU2002250977A1 (en) 2002-09-04

Family

ID=7674848

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002250977A Abandoned AU2002250977A1 (en) 2001-02-21 2002-02-20 Combination of active ingredients consisting of the racemate of tramadol and of (+)-o-desmethyltramadol

Country Status (3)

Country Link
AU (1) AU2002250977A1 (en)
DE (1) DE10108123A1 (en)
WO (1) WO2002066025A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10225315A1 (en) * 2002-06-06 2003-12-24 Gruenenthal Gmbh Active substance salts and esters of 1-dimethylamino-3- (3-methoxyphenyl) -2-methylpentan-3-ol and 3- (3-dimethylamino-1-ethyl-1-hydroxy-2-methylpropyl) - phenol
DE102006006532B4 (en) 2006-02-10 2007-11-08 Biogenerics Pharma Gmbh Pharmaceutical preparation
EP2022778A1 (en) 2007-08-07 2009-02-11 Laboratorios del Dr. Esteve S.A. A crystalline form of (R,R)-tramadol-(S)-naproxene salt
US10702485B2 (en) 2011-07-09 2020-07-07 Syntrix Biosystems Inc. Compositions and methods for overcoming resistance to tramadol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19601744C2 (en) * 1996-01-19 1998-04-16 Gruenenthal Gmbh Process for the preparation of the enantiomers of O-demethyltramadol
DE19712398A1 (en) * 1997-03-25 1998-10-01 Gruenenthal Gmbh Oral use of (+) - 0-demethyltramadol as a pain reliever

Also Published As

Publication number Publication date
WO2002066025A3 (en) 2003-04-24
DE10108123A1 (en) 2002-10-02
WO2002066025A2 (en) 2002-08-29

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase