HUP0100562A2 - Szferoidok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények - Google Patents

Szferoidok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0100562A2
HUP0100562A2 HU0100562A HUP0100562A HUP0100562A2 HU P0100562 A2 HUP0100562 A2 HU P0100562A2 HU 0100562 A HU0100562 A HU 0100562A HU P0100562 A HUP0100562 A HU P0100562A HU P0100562 A2 HUP0100562 A2 HU P0100562A2
Authority
HU
Hungary
Prior art keywords
spheroids
compositions containing
pharmaceutical compositions
preparation
tiagabine
Prior art date
Application number
HU0100562A
Other languages
English (en)
Inventor
Patrice Debregeas
Gérard LeDuc
Pascal Oury
Pascal Suplie
Original Assignee
Laboratoires Des Produits Ethiques Ethypharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Des Produits Ethiques Ethypharm filed Critical Laboratoires Des Produits Ethiques Ethypharm
Publication of HUP0100562A2 publication Critical patent/HUP0100562A2/hu
Publication of HUP0100562A3 publication Critical patent/HUP0100562A3/hu
Publication of HU230053B1 publication Critical patent/HU230053B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A találmány új gyógyszerészeti formára vonatkozik, amely szferoidformájú, és a tiagabin kivételével egy vagy több hatóanyagottartalmaz. A találmány az ilyen szferoidok előállítására szolgálóeljárást és az ezeket tartalmazó több részből álló gyógyszerészetikészítményeket is magában foglalja. Ó
HU0100562A 1997-11-21 1998-11-19 Szferoidok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények HU230053B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR97/14631 1997-11-21
FR9714631A FR2771291B1 (fr) 1997-11-21 1997-11-21 Spheroides, procede de preparation et compositions pharmaceutiques
PCT/IB1998/001911 WO1999026608A1 (fr) 1997-11-21 1998-11-19 Spheroides, procede de preparation et compositions pharmaceutiques

Publications (3)

Publication Number Publication Date
HUP0100562A2 true HUP0100562A2 (hu) 2002-05-29
HUP0100562A3 HUP0100562A3 (en) 2002-08-28
HU230053B1 HU230053B1 (hu) 2015-06-29

Family

ID=9513635

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0100562A HU230053B1 (hu) 1997-11-21 1998-11-19 Szferoidok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények

Country Status (29)

Country Link
US (1) US6077544A (hu)
EP (1) EP1032374B1 (hu)
JP (1) JP2001523706A (hu)
KR (1) KR100502938B1 (hu)
CN (1) CN1223341C (hu)
AT (1) ATE246496T1 (hu)
AU (1) AU744580B2 (hu)
BG (1) BG65117B1 (hu)
BR (1) BR9814672A (hu)
CA (1) CA2310147C (hu)
CZ (1) CZ299110B6 (hu)
DE (1) DE69817010T2 (hu)
DK (1) DK1032374T3 (hu)
EA (1) EA003324B1 (hu)
ES (1) ES2203989T3 (hu)
FR (1) FR2771291B1 (hu)
HR (1) HRP20000323B1 (hu)
HU (1) HU230053B1 (hu)
IL (2) IL136215A0 (hu)
MX (1) MXPA00004959A (hu)
NO (1) NO329728B1 (hu)
NZ (1) NZ504662A (hu)
PL (1) PL193878B1 (hu)
PT (1) PT1032374E (hu)
SK (1) SK284493B6 (hu)
TR (1) TR200002130T2 (hu)
WO (1) WO1999026608A1 (hu)
YU (1) YU31000A (hu)
ZA (1) ZA9810631B (hu)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
EP1165042B1 (fr) 1999-04-06 2005-02-02 Ethypharm Suspension pharmaceutique buvable d'ibuprofene
FR2794646B1 (fr) * 1999-06-09 2001-09-21 Ethypharm Lab Prod Ethiques Microgranules de sulfate de morphine, procede de preparation et composition les contenant
DK1414956T3 (da) 2001-06-22 2008-03-03 Genencor Int Höjt påvirkningsresistente granula
AR034813A1 (es) † 2001-07-20 2004-03-17 Novartis Ag Composiciones farmaceuticas y uso de las mismas
FR2830447B1 (fr) * 2001-10-09 2004-04-16 Flamel Tech Sa Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
FR2837100B1 (fr) * 2002-03-18 2004-07-23 Flamel Tech Sa Comprimes a bases de microcapsules a liberation modifiee
PT1492511E (pt) 2002-04-09 2009-04-09 Flamel Tech Sa Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
CA2480824A1 (fr) * 2002-04-09 2003-10-16 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline
FR2838647B1 (fr) * 2002-04-23 2006-02-17 Particules enrobees a liberation prolongee, leur procede de preparation et comprimes les contenant
US20040013737A1 (en) * 2002-07-19 2004-01-22 Philippe Becourt Taste masked oral composition of telithromycin
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
US9107804B2 (en) * 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
NZ523946A (en) 2003-01-31 2004-06-25 Carl Ernest Alexander Portable hygiene compositions comprising a semi-solid gel and active ingredients in bead form for use in personal oral, dental or skin care
ES2221804B1 (es) * 2003-06-18 2006-04-01 Lipofoods, S.L. Microcapsulas para la administracion de ingredientes activos.
JP5171038B2 (ja) * 2003-10-10 2013-03-27 エティファルム イチョウ・エキスを含む放出持続性の微小顆粒およびそのような顆粒の製造方法
FR2861990B1 (fr) 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
EP1737433B1 (en) * 2004-04-12 2007-11-14 Pfizer Products Incorporated Taste-masked drugs in rupturing multiparticulates
CA2569961A1 (en) * 2004-06-10 2005-12-29 Glatt Air Techniques, Inc Controlled release pharmaceutical formulation
FR2883179B1 (fr) 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US20100233257A1 (en) * 2006-06-09 2010-09-16 Ethypharm Low dose sublingual tablets of opioid analgesics and preparation process
US20070286900A1 (en) * 2006-06-09 2007-12-13 Catherine Herry Low dose tablets of opioid analgesics and preparation process
US11116728B2 (en) 2006-11-30 2021-09-14 Bend Research, Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
WO2008065504A1 (en) * 2006-11-30 2008-06-05 Pfizer Products Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
EP2468263A1 (en) 2010-12-23 2012-06-27 Laboratorios Del. Dr. Esteve, S.A. Compressed solid dosage forms
EP3790822A4 (en) 2018-05-11 2022-01-26 Stolle Machinery Company, LLC PROCESS SHANK TOOLING ARRANGEMENT
CN112135785B (zh) 2018-05-11 2022-04-19 斯多里机械有限责任公司 快速更换式转移组件
WO2019217607A2 (en) 2018-05-11 2019-11-14 Stolle Machinery Company, Llc Infeed assembly quick change features
CN115958118A (zh) 2018-05-11 2023-04-14 斯多里机械有限责任公司 快速更换工具组件
CN112105916B (zh) 2018-05-11 2024-01-02 斯多里机械有限责任公司 馈入组件全面检查组件
WO2019217711A1 (en) 2018-05-11 2019-11-14 Stolle Machinery Company, Llc Drive assembly
JP7312196B2 (ja) 2018-05-11 2023-07-20 ストール マシーナリ カンパニー，エルエルシー 回転マニホールド
US11420242B2 (en) 2019-08-16 2022-08-23 Stolle Machinery Company, Llc Reformer assembly

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
CA1338596C (en) * 1988-09-27 1996-09-17 Hiroyoshi Koyama Granules having core and their production
EP0418596A3 (en) * 1989-09-21 1991-10-23 American Cyanamid Company Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
JP2572673B2 (ja) * 1990-07-25 1997-01-16 エスエス製薬株式会社 徐放性錠剤
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
GB9117361D0 (en) * 1991-08-12 1991-09-25 Euro Celtique Sa Oral dosage form
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
SK279684B6 (sk) * 1993-06-14 1999-02-11 Janssen Pharmaceutica N.V. Tableta a spôsob jej výroby
SE9402422D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
FR2771292B1 (fr) * 1997-11-21 2000-02-18 Ethypharm Lab Prod Ethiques Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques

Also Published As

Publication number Publication date
NZ504662A (en) 2002-09-27
KR20010032329A (ko) 2001-04-16
KR100502938B1 (ko) 2005-07-25
ES2203989T3 (es) 2004-04-16
DK1032374T3 (da) 2003-11-24
ATE246496T1 (de) 2003-08-15
CZ299110B6 (cs) 2008-04-23
EP1032374A1 (fr) 2000-09-06
CN1282239A (zh) 2001-01-31
IL136215A (en) 2006-12-31
DE69817010T2 (de) 2004-05-27
HUP0100562A3 (en) 2002-08-28
HRP20000323A2 (en) 2001-06-30
DE69817010D1 (de) 2003-09-11
AU1170499A (en) 1999-06-15
EA003324B1 (ru) 2003-04-24
WO1999026608A1 (fr) 1999-06-03
HU230053B1 (hu) 2015-06-29
SK7562000A3 (en) 2001-06-11
NO329728B1 (no) 2010-12-06
JP2001523706A (ja) 2001-11-27
BG104511A (en) 2001-04-30
FR2771291A1 (fr) 1999-05-28
EA200000548A1 (ru) 2000-12-25
EP1032374B1 (fr) 2003-08-06
HRP20000323B1 (en) 2006-07-31
TR200002130T2 (tr) 2000-12-21
PT1032374E (pt) 2003-12-31
FR2771291B1 (fr) 2000-02-25
MXPA00004959A (es) 2002-10-17
CN1223341C (zh) 2005-10-19
NO20002605L (no) 2000-07-05
PL340659A1 (en) 2001-02-12
IL136215A0 (en) 2001-05-20
AU744580B2 (en) 2002-02-28
YU31000A (sh) 2002-11-15
BR9814672A (pt) 2000-10-03
BG65117B1 (bg) 2007-03-30
ZA9810631B (en) 1999-05-24
CA2310147A1 (fr) 1999-06-03
US6077544A (en) 2000-06-20
CZ20001849A3 (cs) 2000-10-11
SK284493B6 (sk) 2005-05-05
NO20002605D0 (no) 2000-05-19
PL193878B1 (pl) 2007-03-30
CA2310147C (fr) 2010-05-25

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