FR2771292B1 - Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques - Google Patents

Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques

Info

Publication number
FR2771292B1
FR2771292B1 FR9714635A FR9714635A FR2771292B1 FR 2771292 B1 FR2771292 B1 FR 2771292B1 FR 9714635 A FR9714635 A FR 9714635A FR 9714635 A FR9714635 A FR 9714635A FR 2771292 B1 FR2771292 B1 FR 2771292B1
Authority
FR
France
Prior art keywords
spheroids
tiagabine
preparation
pharmaceutical compositions
containing spheroids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9714635A
Other languages
English (en)
Other versions
FR2771292A1 (fr
Inventor
Patrice Debregeas
Gerard Leduc
Pascal Oury
Pascal Suplie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethypharm SAS
Original Assignee
Ethypharm SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9714635A priority Critical patent/FR2771292B1/fr
Application filed by Ethypharm SAS filed Critical Ethypharm SAS
Priority to AU11703/99A priority patent/AU1170399A/en
Priority to JP2000521828A priority patent/JP2001523719A/ja
Priority to ES98954682T priority patent/ES2173638T3/es
Priority to DK98954682T priority patent/DK1032391T3/da
Priority to DE69805433T priority patent/DE69805433T2/de
Priority to PT98954682T priority patent/PT1032391E/pt
Priority to EP98954682A priority patent/EP1032391B1/fr
Priority to AT98954682T priority patent/ATE217525T1/de
Priority to PCT/IB1998/001910 priority patent/WO1999026626A1/fr
Priority to ARP980105922 priority patent/AR017652A1/es
Priority to ZA9810630A priority patent/ZA9810630B/xx
Priority to US09/198,564 priority patent/US6139877A/en
Publication of FR2771292A1 publication Critical patent/FR2771292A1/fr
Application granted granted Critical
Publication of FR2771292B1 publication Critical patent/FR2771292B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
FR9714635A 1997-11-21 1997-11-21 Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques Expired - Fee Related FR2771292B1 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR9714635A FR2771292B1 (fr) 1997-11-21 1997-11-21 Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques
EP98954682A EP1032391B1 (fr) 1997-11-21 1998-11-19 Spheroides contenant tiagabine, procede de preparation et compositions pharmaceutiques
ES98954682T ES2173638T3 (es) 1997-11-21 1998-11-19 Esferoides que contienen tiagabina, procedimiento de fabricacion y composiciones farmaceuticas.
DK98954682T DK1032391T3 (da) 1997-11-21 1998-11-19 Sfæroider indeholdende tiagabin, fremstillingsproces og farmaceutisk sammensætning
DE69805433T DE69805433T2 (de) 1997-11-21 1998-11-19 Tiagabin enthaltende spheroide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
PT98954682T PT1032391E (pt) 1997-11-21 1998-11-19 Esferoides contendo tiagabina processo de preparacao e composicoes farmaceuticas
AU11703/99A AU1170399A (en) 1997-11-21 1998-11-19 Spheroids containing tiagabine, preparation process and pharmaceutical comp ositions
AT98954682T ATE217525T1 (de) 1997-11-21 1998-11-19 Tiagabin enthaltende spheroide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
PCT/IB1998/001910 WO1999026626A1 (fr) 1997-11-21 1998-11-19 Spheroides contenant tiagabine, procede de preparation et compositions pharmaceutiques
JP2000521828A JP2001523719A (ja) 1997-11-21 1998-11-19 チアガビンを含有するスフェロイド、製造方法および医薬組成物
ARP980105922 AR017652A1 (es) 1997-11-21 1998-11-20 Esferoides que contienen uno o varios principios activos excepto tiagabina, procedimiento para su preparacion, composiciones farmaceuticas que loscontienen y procedimiento para su preparacion
ZA9810630A ZA9810630B (en) 1997-11-21 1998-11-20 Spheroids containing tiagabine preparation process and pharmaceutical compositions
US09/198,564 US6139877A (en) 1997-11-21 1998-11-23 Spheroids containing tiagabine, preparation process and pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9714635A FR2771292B1 (fr) 1997-11-21 1997-11-21 Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques

Publications (2)

Publication Number Publication Date
FR2771292A1 FR2771292A1 (fr) 1999-05-28
FR2771292B1 true FR2771292B1 (fr) 2000-02-18

Family

ID=9513639

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9714635A Expired - Fee Related FR2771292B1 (fr) 1997-11-21 1997-11-21 Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques

Country Status (12)

Country Link
US (1) US6139877A (fr)
EP (1) EP1032391B1 (fr)
JP (1) JP2001523719A (fr)
AT (1) ATE217525T1 (fr)
AU (1) AU1170399A (fr)
DE (1) DE69805433T2 (fr)
DK (1) DK1032391T3 (fr)
ES (1) ES2173638T3 (fr)
FR (1) FR2771292B1 (fr)
PT (1) PT1032391E (fr)
WO (1) WO1999026626A1 (fr)
ZA (1) ZA9810630B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
FR2771291B1 (fr) * 1997-11-21 2000-02-25 Ethypharm Lab Prod Ethiques Spheroides, procede de preparation et compositions pharmaceutiques
BR0009557A (pt) 1999-04-06 2002-05-28 Ethypharm Lab Prod Ethiques Suspensão farmacêutica para beber de ibuprofeno
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
FR2845289B1 (fr) 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
ES2221804B1 (es) * 2003-06-18 2006-04-01 Lipofoods, S.L. Microcapsulas para la administracion de ingredientes activos.
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP1802285B1 (fr) 2004-10-21 2013-02-27 Aptalis Pharmatech, Inc. Compositions pharmaceutiques a saveur masquee avec substances porogenes gastrosolubles
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
AU2010325746B2 (en) 2009-12-02 2016-02-25 Adare Pharmaceuticals S.R.L. Fexofenadine microcapsules and compositions containing them
TW201127375A (en) * 2010-01-08 2011-08-16 Eurand Inc Taste masked topiramate composition and an orally disintegrating tablet comprising the same
MX2013009253A (es) 2011-02-11 2013-12-16 Zx Pharma Llc Formulaciones multiparticuladas de l-mentol y metodos relacionados.
US8911780B2 (en) 2011-02-11 2014-12-16 Zx Pharma, Llc Multiparticulate L-menthol formulations and related methods
US8808736B2 (en) 2011-02-11 2014-08-19 Zx Pharma, Llc Enteric coated multiparticulate controlled release peppermint oil composition and related methods
CA2881992C (fr) 2013-04-23 2016-11-22 Zx Pharma, Llc Composition multiparticulaire, revetue, enterique, a liberation controlee d'huile de menthe poivree et procedes associes

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
JPS62153213A (ja) * 1985-12-26 1987-07-08 Dai Ichi Seiyaku Co Ltd 腸溶性粒状物
NZ230763A (en) * 1988-09-27 1991-10-25 Takeda Chemical Industries Ltd Production of granules having a core by spraying the cores with a dispersion of hydroxypropylcellulose, optionally incorporating an active ingredient
JP2572673B2 (ja) * 1990-07-25 1997-01-16 エスエス製薬株式会社 徐放性錠剤
DK58291D0 (da) * 1991-04-02 1991-04-02 Novo Nordisk As Krystalinsk stof og dets fremstilling
ZA923474B (en) * 1991-05-20 1993-01-27 Marion Merrell Dow Inc Diltiazem formulation
US5326570A (en) * 1991-07-23 1994-07-05 Pharmavene, Inc. Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
WO1995005808A1 (fr) * 1993-08-24 1995-03-02 Abbott Laboratories Procede de production de comprimes a base d'huile
US5430021A (en) * 1994-03-18 1995-07-04 Pharmavene, Inc. Hydrophobic drug delivery systems
US5484608A (en) * 1994-03-28 1996-01-16 Pharmavene, Inc. Sustained-release drug delivery system
US5447729A (en) * 1994-04-07 1995-09-05 Pharmavene, Inc. Multilamellar drug delivery systems
ZA953078B (en) * 1994-04-28 1996-01-05 Alza Corp Effective therapy for epilepsies
US5750140A (en) * 1994-05-20 1998-05-12 Novo Nordisk A/S Transdermal delivery of tiagabine
ATE211911T1 (de) * 1995-05-05 2002-02-15 Novo Nordisk As Tiagabinhydrochlorid enthaltendes arzneimittel und verfahren zu dessen herstellung
US5914333A (en) * 1996-07-31 1999-06-22 Novo Nordisk A/S Treatment of psychotic disorders
HU228855B1 (en) * 1997-03-12 2013-06-28 Abbott Lab Hydrophilic binary systems for the administration of cyclosporine

Also Published As

Publication number Publication date
ATE217525T1 (de) 2002-06-15
PT1032391E (pt) 2002-09-30
FR2771292A1 (fr) 1999-05-28
US6139877A (en) 2000-10-31
DE69805433D1 (de) 2002-06-20
AU1170399A (en) 1999-06-15
EP1032391A1 (fr) 2000-09-06
EP1032391B1 (fr) 2002-05-15
DE69805433T2 (de) 2002-11-07
DK1032391T3 (da) 2002-09-09
WO1999026626A1 (fr) 1999-06-03
ES2173638T3 (es) 2002-10-16
JP2001523719A (ja) 2001-11-27
ZA9810630B (en) 1999-05-24

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Legal Events

Date Code Title Description
GC Lien (pledge) constituted
ST Notification of lapse
GC Lien (pledge) constituted

Effective date: 20140519

GC Lien (pledge) constituted

Effective date: 20160120

RG Lien (pledge) cancelled

Effective date: 20160226

RG Lien (pledge) cancelled

Effective date: 20170418