HUE054955T2 - 3-Formilrifamicin S 3-(4-cinnamil-L-piperazinil)-amino származékait tartalmazó gyógyszerészeti készítmények - Google Patents

3-Formilrifamicin S 3-(4-cinnamil-L-piperazinil)-amino származékait tartalmazó gyógyszerészeti készítmények

Info

Publication number
HUE054955T2
HUE054955T2 HUE13829445A HUE13829445A HUE054955T2 HU E054955 T2 HUE054955 T2 HU E054955T2 HU E13829445 A HUE13829445 A HU E13829445A HU E13829445 A HUE13829445 A HU E13829445A HU E054955 T2 HUE054955 T2 HU E054955T2
Authority
HU
Hungary
Prior art keywords
formylrifamycin
cinnamyl
piperazinyl
pharmaceutical formulations
formulations containing
Prior art date
Application number
HUE13829445A
Other languages
English (en)
Inventor
Rumyana Gueorguieva Konstantinova
Kiril Asenov Ninov
Velichka Llieva Apostolova-Dimova
Evtimia Ivanova Stefanova
Rossen Krumov Koytchev
Original Assignee
Adipharm Ead
Fudulov Bozhidar Lyubenov
Fudulov Lyibomir Bozhidarov
APOSTOLOVA DIMOVA Velichka llieva
Evtimia Ivanova Stefanova
Rossen Krumov Koytchev
Ditchev Consulting Ood
Kiril Asenov Ninov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adipharm Ead, Fudulov Bozhidar Lyubenov, Fudulov Lyibomir Bozhidarov, APOSTOLOVA DIMOVA Velichka llieva, Evtimia Ivanova Stefanova, Rossen Krumov Koytchev, Ditchev Consulting Ood, Kiril Asenov Ninov filed Critical Adipharm Ead
Publication of HUE054955T2 publication Critical patent/HUE054955T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08Bridged systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Chemistry (AREA)
HUE13829445A 2012-08-13 2013-08-09 3-Formilrifamicin S 3-(4-cinnamil-L-piperazinil)-amino származékait tartalmazó gyógyszerészeti készítmények HUE054955T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BG11128812 2012-08-13

Publications (1)

Publication Number Publication Date
HUE054955T2 true HUE054955T2 (hu) 2021-10-28

Family

ID=50101135

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE13829445A HUE054955T2 (hu) 2012-08-13 2013-08-09 3-Formilrifamicin S 3-(4-cinnamil-L-piperazinil)-amino származékait tartalmazó gyógyszerészeti készítmények

Country Status (18)

Country Link
US (2) US9682997B2 (hu)
EP (1) EP2882435B8 (hu)
JP (2) JP6400580B2 (hu)
KR (1) KR102210848B1 (hu)
CN (2) CN107840854A (hu)
BR (1) BR112015002945B1 (hu)
CA (1) CA2881958C (hu)
EA (1) EA029363B1 (hu)
ES (1) ES2876004T3 (hu)
HK (2) HK1206980A1 (hu)
HU (1) HUE054955T2 (hu)
IN (1) IN2015DN02009A (hu)
MX (1) MX2015001963A (hu)
PL (1) PL2882435T3 (hu)
PT (1) PT2882435T (hu)
UA (1) UA120030C2 (hu)
WO (1) WO2014026254A1 (hu)
ZA (1) ZA201501268B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2020102511A (ru) * 2017-06-26 2021-07-27 Биофер С.П.А. Соединения пиридо-имидазо рифамицина в качестве антибактериального средства
TWI731295B (zh) * 2019-01-24 2021-06-21 宏碁股份有限公司 顯示裝置以及控制顯示裝置的方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1478563A (en) 1975-03-05 1977-07-06 Lepetit Spa Rifamycin derivatives
GR64108B (en) 1977-04-15 1980-01-24 Dso Pharmachim Method for the preparation of azomethine-derivatives of rifamycin s.v
US4179439A (en) * 1977-07-01 1979-12-18 Intreprinderea De Antibiotice Iasi Rifamycins and method for their preparation
US4193020A (en) 1978-05-22 1980-03-11 Sperry Rand Corporation Phase lock control system with trajectory correction
JPS5738742A (en) * 1980-08-21 1982-03-03 Kawasaki Kasei Chem Ltd Preparation of 1,4-dihydroanthraquinone
JPS5695190A (en) * 1980-09-17 1981-08-01 Intorepurinderea De Anteibiote Manufacture of rifamycin derivative
IT1201963B (it) * 1983-03-24 1989-02-02 Prodotti Antibiotici Spa Derivati delle rifamicine e procedimento per la loro preparazione
JPS6143132A (ja) * 1984-08-06 1986-03-01 Takeda Chem Ind Ltd キノン誘導体,その製造法およびそれを含んでなる医薬組成物
WO1987002361A1 (en) * 1985-10-18 1987-04-23 Ciba-Geigy Ag Substituted 4-benzyl-piperazinyl compounds
IT1202424B (it) * 1987-01-26 1989-02-09 Prodotti Antibiotici Spa Sali di un derivato rifamicinico
EP0284552A1 (de) * 1987-03-06 1988-09-28 Ciba-Geigy Ag 4-Benzyl-piperazinyl-Hydrazone
BG48618A1 (en) 1988-02-23 1991-04-15 Nauchen Inst Promishlena Mikro Method for preparing riphampycin
JPH02215716A (ja) * 1989-02-08 1990-08-28 Farmitalia Carlo Erba Spa 3―(n―ピペリジノメチル―アジノ)メチルリファマイシンsを活性成分として含有する薬剤組成物
US5095108A (en) 1990-08-28 1992-03-10 Technologichen Kombinat Za Promishlena Microbiologia Non-solvated crystalline form "A" of 3-(4-cynnamyl-1-piperazinyl)iminomethylrifamycine SV and a method of its production
BG64021B1 (bg) 1998-11-04 2003-10-31 КОНСТАНТИНОВА Румяна Натриева сол на 3-(4-цинамил-1-пиперазинил)-иминометил рифамицин и метод за получаването й
DE10015814A1 (de) * 2000-03-30 2001-10-11 Max Planck Gesellschaft Arzneimittel zur Stimulierung der Leukopoese, zur Behandlung von Tumor- und Protozoenerkrankungen und Verfahren zu seiner Herstellung
DE10038101A1 (de) * 2000-08-04 2002-02-14 Degussa Verfahren zur Herstellung von 2-(4-Methyl-3-pentenyl)-anthrachinon
UA80393C2 (uk) * 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
CN101031572B (zh) * 2004-07-22 2010-12-08 坎布里Ip风险投资有限合伙公司 (r/s)利福霉素衍生物,它们的制备和药物组合物
GB0505909D0 (en) * 2005-03-23 2005-04-27 Univ Leeds Formulations

Also Published As

Publication number Publication date
EP2882435B1 (en) 2021-03-17
WO2014026254A1 (en) 2014-02-20
CN104736152B (zh) 2018-01-23
IN2015DN02009A (hu) 2015-08-14
HK1248691A1 (zh) 2018-10-19
CN104736152A (zh) 2015-06-24
JP2018199718A (ja) 2018-12-20
KR20150042275A (ko) 2015-04-20
US20150368263A1 (en) 2015-12-24
BR112015002945B1 (pt) 2021-08-31
US9682997B2 (en) 2017-06-20
PL2882435T3 (pl) 2021-10-04
EP2882435B8 (en) 2024-01-03
UA120030C2 (uk) 2019-09-25
HK1206980A1 (en) 2016-01-22
EP2882435A1 (en) 2015-06-17
KR102210848B1 (ko) 2021-02-02
EP2882435A4 (en) 2017-05-03
US20170283433A1 (en) 2017-10-05
JP2015528823A (ja) 2015-10-01
JP6694029B2 (ja) 2020-05-13
CA2881958A1 (en) 2014-02-20
BR112015002945A8 (pt) 2018-01-16
EA029363B1 (ru) 2018-03-30
CN107840854A (zh) 2018-03-27
MX2015001963A (es) 2015-06-04
BR112015002945A2 (pt) 2017-12-05
CA2881958C (en) 2019-08-27
US9981985B2 (en) 2018-05-29
PT2882435T (pt) 2021-06-18
ES2876004T3 (es) 2021-11-11
EA201590278A1 (ru) 2015-07-30
ZA201501268B (en) 2016-01-27
JP6400580B2 (ja) 2018-10-03

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