HUE037849T2 - Cirkuláris permutációval módosított ligandumok agonistaként és antagonistaként - Google Patents

Cirkuláris permutációval módosított ligandumok agonistaként és antagonistaként

Info

Publication number
HUE037849T2
HUE037849T2 HUE13801437A HUE13801437A HUE037849T2 HU E037849 T2 HUE037849 T2 HU E037849T2 HU E13801437 A HUE13801437 A HU E13801437A HU E13801437 A HUE13801437 A HU E13801437A HU E037849 T2 HUE037849 T2 HU E037849T2
Authority
HU
Hungary
Prior art keywords
agonists
antagonists
circular permutation
ligands modified
ligands
Prior art date
Application number
HUE13801437A
Other languages
English (en)
Inventor
Juan Alvarez
Jean Chamoun
Original Assignee
Alkermes Pharma Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkermes Pharma Ireland Ltd filed Critical Alkermes Pharma Ireland Ltd
Publication of HUE037849T2 publication Critical patent/HUE037849T2/hu

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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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HUE13801437A 2012-06-08 2013-06-06 Cirkuláris permutációval módosított ligandumok agonistaként és antagonistaként HUE037849T2 (hu)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261657285P 2012-06-08 2012-06-08
US201261657264P 2012-06-08 2012-06-08
US201261657378P 2012-06-08 2012-06-08
US201261723081P 2012-11-06 2012-11-06
US201361778812P 2013-03-13 2013-03-13
US201361778575P 2013-03-13 2013-03-13

Publications (1)

Publication Number Publication Date
HUE037849T2 true HUE037849T2 (hu) 2018-09-28

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Family Applications (2)

Application Number Title Priority Date Filing Date
HUE13801437A HUE037849T2 (hu) 2012-06-08 2013-06-06 Cirkuláris permutációval módosított ligandumok agonistaként és antagonistaként
HUE18162555A HUE052908T2 (hu) 2012-06-08 2013-06-06 Cirkuláris permutációval módosított, agonista és antagonista ligandumok

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE18162555A HUE052908T2 (hu) 2012-06-08 2013-06-06 Cirkuláris permutációval módosított, agonista és antagonista ligandumok

Country Status (20)

Country Link
US (8) US9296801B2 (hu)
EP (5) EP2874639B1 (hu)
JP (7) JP6234446B2 (hu)
AU (3) AU2013271542B2 (hu)
CA (3) CA2869674A1 (hu)
CY (2) CY1120522T1 (hu)
DK (2) DK3401402T3 (hu)
ES (4) ES2675784T3 (hu)
HK (3) HK1203969A1 (hu)
HR (2) HRP20180914T1 (hu)
HU (2) HUE037849T2 (hu)
LT (2) LT3401402T (hu)
ME (1) ME03079B (hu)
NZ (4) NZ715099A (hu)
PL (2) PL2859015T3 (hu)
PT (2) PT3401402T (hu)
RS (2) RS61391B1 (hu)
SI (2) SI2859015T1 (hu)
TR (2) TR201808753T4 (hu)
WO (3) WO2013184938A2 (hu)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013184938A2 (en) * 2012-06-08 2013-12-12 Alkermes. Inc. Fusion polypeptides comprising mucin-domain polypeptide linkers
AU2015364396B2 (en) * 2014-12-19 2018-08-09 Alkermes, Inc. Single chain Fc fusion proteins
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AU2013271541C1 (en) 2018-01-18
US20140234962A1 (en) 2014-08-21
EP2858672B1 (en) 2018-04-04
JP2015520193A (ja) 2015-07-16
WO2013184939A3 (en) 2014-01-30
JP2019195332A (ja) 2019-11-14
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NZ715099A (en) 2018-12-21
ME03079B (me) 2019-01-20
US10183979B2 (en) 2019-01-22
EP3401402A1 (en) 2018-11-14
US20130336925A1 (en) 2013-12-19
JP2015525216A (ja) 2015-09-03
US20160237132A1 (en) 2016-08-18
WO2013184939A2 (en) 2013-12-12
CY1124525T1 (el) 2022-07-22
EP2874639A2 (en) 2015-05-27
US9359415B2 (en) 2016-06-07
CA2869674A1 (en) 2013-12-12
EP2859015A4 (en) 2015-11-18
JP2023109948A (ja) 2023-08-08
AU2013271545A1 (en) 2014-10-16
NZ630849A (en) 2016-04-29
PT3401402T (pt) 2020-11-11
US9428563B2 (en) 2016-08-30
TR201808753T4 (tr) 2018-07-23
US9296801B2 (en) 2016-03-29
JP6388408B2 (ja) 2018-09-12
HRP20180914T1 (hr) 2018-07-27
RS61391B1 (sr) 2021-02-26
EP2874639B1 (en) 2018-03-28
WO2013184942A1 (en) 2013-12-12
EP3401402B1 (en) 2020-10-14
EP2859015A1 (en) 2015-04-15
LT3401402T (lt) 2020-12-28
EP3825405A1 (en) 2021-05-26
EP2858672A2 (en) 2015-04-15
HK1210055A1 (en) 2016-04-15
HRP20201973T1 (hr) 2021-02-05
EP2874639A4 (en) 2016-05-11
JP2018038389A (ja) 2018-03-15
US10023623B2 (en) 2018-07-17
AU2013271541B2 (en) 2016-03-17
AU2013271541A1 (en) 2014-10-23
EP2859015B1 (en) 2018-03-21
AU2013271545C1 (en) 2017-09-28
JP2022050391A (ja) 2022-03-30
SI3401402T1 (sl) 2021-03-31
CA2869787C (en) 2021-11-23
LT2859015T (lt) 2018-07-10
HUE052908T2 (hu) 2021-05-28
US10407481B2 (en) 2019-09-10

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