HUE026237T2 - Hydroxylated cyclopenta [d] pyrimidines as AKT protein kinase inhibitors - Google Patents

Hydroxylated cyclopenta [d] pyrimidines as AKT protein kinase inhibitors Download PDF

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Publication number
HUE026237T2
HUE026237T2 HUE11166125A HUE11166125A HUE026237T2 HU E026237 T2 HUE026237 T2 HU E026237T2 HU E11166125 A HUE11166125 A HU E11166125A HU E11166125 A HUE11166125 A HU E11166125A HU E026237 T2 HUE026237 T2 HU E026237T2
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Hungary
Prior art keywords
alkyl
cancer
mmol
compound
methyl
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HUE11166125A
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English (en)
Hungarian (hu)
Inventor
Ian S Mitchell
James F Blake
Rui Xu
Nicholas C Kallan
Dengming Xiao
Keith Lee Spencer
Josef R Bencsik
Jun Liang
Brian Safina
Birong Zhang
Christine Chabot
Steven Do
Eli W Wallace
Anna L Banka
Stephen T Schlachter
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Array Biopharma Inc
Genentech Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38686743&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE026237(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Array Biopharma Inc, Genentech Inc filed Critical Array Biopharma Inc
Publication of HUE026237T2 publication Critical patent/HUE026237T2/en

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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HUE11166125A 2006-07-06 2007-07-05 Hydroxylated cyclopenta [d] pyrimidines as AKT protein kinase inhibitors HUE026237T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81871806P 2006-07-06 2006-07-06

Publications (1)

Publication Number Publication Date
HUE026237T2 true HUE026237T2 (en) 2016-06-28

Family

ID=38686743

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE11166125A HUE026237T2 (en) 2006-07-06 2007-07-05 Hydroxylated cyclopenta [d] pyrimidines as AKT protein kinase inhibitors

Country Status (34)

Country Link
EP (4) EP2402325B1 (OSRAM)
JP (4) JP5266216B2 (OSRAM)
KR (5) KR20150051240A (OSRAM)
CN (2) CN102816124A (OSRAM)
AR (3) AR061842A1 (OSRAM)
AT (1) ATE524447T1 (OSRAM)
AU (1) AU2007269060B2 (OSRAM)
BR (3) BR122013028012B8 (OSRAM)
CA (2) CA2656622C (OSRAM)
CL (1) CL2007001993A1 (OSRAM)
CO (1) CO6150161A2 (OSRAM)
CR (1) CR10600A (OSRAM)
CY (1) CY1112117T1 (OSRAM)
DK (2) DK2049501T3 (OSRAM)
ES (3) ES2372774T3 (OSRAM)
HR (1) HRP20110908T1 (OSRAM)
HU (1) HUE026237T2 (OSRAM)
IL (2) IL196028A (OSRAM)
IN (1) IN2014KN02886A (OSRAM)
MA (1) MA31655B1 (OSRAM)
MX (4) MX2008016202A (OSRAM)
MY (1) MY147364A (OSRAM)
NO (1) NO342346B1 (OSRAM)
NZ (3) NZ610633A (OSRAM)
PL (2) PL2402325T3 (OSRAM)
PT (1) PT2049501E (OSRAM)
RS (1) RS52212B (OSRAM)
RU (2) RU2478632C2 (OSRAM)
SG (4) SG188905A1 (OSRAM)
SI (2) SI2402325T1 (OSRAM)
TW (2) TW201332994A (OSRAM)
UA (1) UA95641C2 (OSRAM)
WO (1) WO2008006040A1 (OSRAM)
ZA (1) ZA200900070B (OSRAM)

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US8329701B2 (en) 2006-07-06 2012-12-11 Array Biopharma Inc. Dihydrofuro pyrimidines as AKT protein kinase inhibitors
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EP2240483B8 (en) 2008-01-09 2013-04-03 Array Biopharma, Inc. Pyrimidyl cyclopentanes as akt protein kinase inhibitors
EP2240455B1 (en) * 2008-01-09 2012-12-26 Array Biopharma, Inc. Hydroxylated pyrimidyl cyclopentane as akt protein kinase inhibitor
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SG10201504303SA (en) * 2011-04-01 2015-07-30 Genentech Inc Combinations Of AKT Inhibitor Compounds And Chemotherapeutic Agents, And Methods Of Use
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