HU180744B - Process for producing vindesine-sulfate - Google Patents

Process for producing vindesine-sulfate Download PDF

Info

Publication number
HU180744B
HU180744B HU79EI881A HUEI000881A HU180744B HU 180744 B HU180744 B HU 180744B HU 79EI881 A HU79EI881 A HU 79EI881A HU EI000881 A HUEI000881 A HU EI000881A HU 180744 B HU180744 B HU 180744B
Authority
HU
Hungary
Prior art keywords
vindesine
sulfuric acid
acetonitrile
added
stirring
Prior art date
Application number
HU79EI881A
Other languages
German (de)
English (en)
Hungarian (hu)
Inventor
Stanislaw Rolski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HU180744B publication Critical patent/HU180744B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
HU79EI881A 1978-10-10 1979-10-09 Process for producing vindesine-sulfate HU180744B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94959578A 1978-10-10 1978-10-10

Publications (1)

Publication Number Publication Date
HU180744B true HU180744B (en) 1983-04-29

Family

ID=25489302

Family Applications (1)

Application Number Title Priority Date Filing Date
HU79EI881A HU180744B (en) 1978-10-10 1979-10-09 Process for producing vindesine-sulfate

Country Status (32)

Country Link
EP (1) EP0009996B1 (pt)
JP (1) JPS5553295A (pt)
KR (1) KR850000150B1 (pt)
AR (1) AR225153A1 (pt)
AT (1) AT370422B (pt)
AU (1) AU525702B2 (pt)
BE (1) BE879213A (pt)
BG (1) BG34763A3 (pt)
CA (1) CA1114817A (pt)
CH (2) CH645120A5 (pt)
CS (1) CS235503B2 (pt)
DD (1) DD146461A5 (pt)
DE (1) DE2964913D1 (pt)
DK (1) DK146823C (pt)
EG (1) EG14140A (pt)
ES (1) ES484827A1 (pt)
FI (1) FI70223C (pt)
FR (1) FR2438659A1 (pt)
GB (1) GB2031893B (pt)
GR (1) GR72394B (pt)
HU (1) HU180744B (pt)
IE (1) IE48958B1 (pt)
IL (1) IL58390A (pt)
LU (1) LU81763A1 (pt)
MY (1) MY8500569A (pt)
NZ (1) NZ191744A (pt)
PH (1) PH16092A (pt)
PL (1) PL117678B1 (pt)
PT (1) PT70269A (pt)
RO (1) RO77380A (pt)
YU (1) YU241179A (pt)
ZA (1) ZA795268B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558053A (en) * 1983-12-21 1985-12-10 Eli Lilly And Company Naphthalene-1,5-disulfonate salts of dimeric indole-dihydroindole alkaloids
CN112592357B (zh) * 2020-12-22 2022-03-22 海南长春花药业有限公司 一种硫酸长春地辛的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
US4029663A (en) * 1975-07-10 1977-06-14 Eli Lilly And Company Dimeric anhydro-vinca derivatives
GR69783B (pt) * 1976-09-08 1982-07-07 Lilly Co Eli

Also Published As

Publication number Publication date
KR850000150B1 (ko) 1985-02-28
MY8500569A (en) 1985-12-31
FR2438659A1 (fr) 1980-05-09
DE2964913D1 (en) 1983-03-31
IE48958B1 (en) 1985-06-26
FI70223C (fi) 1986-09-15
FI70223B (fi) 1986-02-28
IE791914L (en) 1980-04-10
PH16092A (en) 1983-06-20
IL58390A (en) 1982-07-30
CH645120A5 (fr) 1984-09-14
LU81763A1 (fr) 1980-01-24
JPS628119B2 (pt) 1987-02-20
FI793065A (fi) 1980-04-11
AR225153A1 (es) 1982-02-26
DD146461A5 (de) 1981-02-11
YU241179A (en) 1983-01-21
CA1114817A (en) 1981-12-22
AU525702B2 (en) 1982-11-25
NZ191744A (en) 1981-05-29
PL117678B1 (en) 1981-08-31
PT70269A (de) 1979-11-01
ES484827A1 (es) 1980-10-01
BE879213A (fr) 1980-04-08
DK422979A (da) 1980-04-11
AT370422B (de) 1983-03-25
GB2031893B (en) 1983-03-30
KR830001282A (ko) 1983-04-30
BG34763A3 (en) 1983-11-15
CS235503B2 (en) 1985-05-15
GB2031893A (en) 1980-04-30
AU5142779A (en) 1980-04-17
EP0009996B1 (en) 1983-02-23
ZA795268B (en) 1981-05-27
GR72394B (pt) 1983-11-01
CH649301A5 (fr) 1985-05-15
EP0009996A1 (en) 1980-04-16
JPS5553295A (en) 1980-04-18
IL58390A0 (en) 1980-01-31
FR2438659B1 (pt) 1983-03-18
DK146823B (da) 1984-01-16
RO77380A (ro) 1981-11-04
PL218756A1 (pt) 1980-06-16
ATA658279A (de) 1982-08-15
DK146823C (da) 1984-07-02
EG14140A (en) 1983-09-30

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628