HRP990129B1 - New compounds of 3-deoxy-desmycosin class and process for the preparation thereof - Google Patents
New compounds of 3-deoxy-desmycosin class and process for the preparation thereofInfo
- Publication number
- HRP990129B1 HRP990129B1 HR990129A HRP990129A HRP990129B1 HR P990129 B1 HRP990129 B1 HR P990129B1 HR 990129 A HR990129 A HR 990129A HR P990129 A HRP990129 A HR P990129A HR P990129 B1 HRP990129 B1 HR P990129B1
- Authority
- HR
- Croatia
- Prior art keywords
- desmycosin
- deoxy
- class
- preparation
- new compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- QRPHLEPFYLNRDA-NLGRAQRVSA-N 2-[(4r,5s,6s,7r,9r,11e,13e,15r,16r)-6-[(2r,3r,4s,5s,6r)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-[[(2r,3r,4r,5r,6r)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,1 Chemical compound O([C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@@H]1O[C@H](C)[C@@H](O)[C@H](N(C)C)[C@H]1O QRPHLEPFYLNRDA-NLGRAQRVSA-N 0.000 abstract 3
- 238000006735 epoxidation reaction Methods 0.000 abstract 2
- 125000000466 oxiranyl group Chemical group 0.000 abstract 2
- 230000002829 reductive effect Effects 0.000 abstract 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Priority Applications (32)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HR990129A HRP990129B1 (en) | 1999-05-03 | 1999-05-03 | New compounds of 3-deoxy-desmycosin class and process for the preparation thereof |
| HK03100593.8A HK1050010A1 (zh) | 1999-05-03 | 2000-05-02 | 3-脱氧-去碳霉糖太乐菌素衍生物和它们的制备方法 |
| NZ515280A NZ515280A (en) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmycosin derivatives and process for their preparation |
| EP00920939A EP1175428B1 (en) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmycosin derivatives and process for their preparation |
| IL14598900A IL145989A0 (en) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmycosin derivatives and process for their preparation |
| HU0201140A HUP0201140A3 (en) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmycosin derivatives and their preparation |
| KR1020017014045A KR100679903B1 (ko) | 1999-05-03 | 2000-05-02 | 3-데옥시-데스미코신 유도체 및 그의 제조 방법 |
| PCT/HR2000/000012 WO2000066602A1 (en) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmycosin derivatives and process for their preparation |
| AU41349/00A AU767549B2 (en) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmycosin derivatives and process for their preparation |
| SK1568-2001A SK283967B6 (sk) | 1999-05-03 | 2000-05-02 | Deriváty 3-deoxy-desmykozínu a spôsob ich prípravy |
| JP2000615631A JP2002543212A (ja) | 1999-05-03 | 2000-05-02 | ３−オキソ−デスマイコシン系の新規化合物及びその製造方法 |
| TR2001/03146T TR200103146T2 (tr) | 1999-05-03 | 2000-05-02 | 3-Deoksi-desmikozin türevleri ve bunları hazırlama işlemi |
| SI200030134T SI1175428T1 (en) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmycosin derivatives and process for their preparation |
| CNB008071519A CN1191263C (zh) | 1999-05-03 | 2000-05-02 | 3－脱氧－去碳霉糖太乐菌素衍生物和它们的制备方法 |
| UA2001118220A UA66927C2 (uk) | 1999-05-03 | 2000-05-02 | Похідні 3-деоксидесмікозину та спосіб їх одержання |
| DK00920939T DK1175428T3 (da) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmocysin-derivater og fremgangsmåde til deres fremstilling |
| EA200101169A EA004059B1 (ru) | 1999-05-03 | 2000-05-02 | Производные 3-деоксидесмикозина |
| CZ20013821A CZ296455B6 (cs) | 1999-05-03 | 2000-05-02 | Deriváty 3-deoxy-desmykosinu a zpusob jejich prípravy |
| AT00920939T ATE238332T1 (de) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmycosin-derivate und verfahren zu ihrer herstellung |
| EEP200100571A EE04594B1 (et) | 1999-05-03 | 2000-05-02 | 3-desoksüdesmükosiini derivaadid ja nende valmistamismeetod |
| DE60002314T DE60002314T2 (de) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmycosin-derivate und verfahren zu ihrer herstellung |
| US09/959,692 US6504035B1 (en) | 1999-03-05 | 2000-05-02 | 3-deoxy-desmycosin derivatives and process for their preparation |
| ES00920939T ES2198302T3 (es) | 1999-05-03 | 2000-05-02 | Derivados de 3-desoxi-desmicosina y su procedimiento de preparacion. |
| CA002368249A CA2368249A1 (en) | 1999-05-03 | 2000-05-02 | 3-deoxy-desmycosin derivatives and process for their preparation |
| MXPA01011089A MXPA01011089A (es) | 1999-05-03 | 2000-05-02 | Derivados de 3-desoxi-desmicosina y proceso para su preparacion. |
| PL00352027A PL352027A1 (en) | 1999-05-03 | 2000-05-02 | Derivatives of 3-deoxy-desmykozyne and method of making same |
| BR0010250-4A BR0010250A (pt) | 1999-05-03 | 2000-05-02 | Compostos da classe 3-desóxi-desmicosina e processo de preparação dos mesmos |
| GEAP20006228A GEP20032927B (en) | 1999-05-03 | 2000-05-02 | 3-Deoxy-Desmycosin Derivatives and Process for Their Preparation |
| ZA200108482A ZA200108482B (en) | 1999-05-03 | 2001-10-16 | 3-deoxy-desmycosin derivatives and process for their preparation. |
| IS6117A IS6117A (is) | 1999-05-03 | 2001-10-19 | 3-deoxý-desmýkósín afleiður og aðferð til framleiðslu á þeim |
| NO20015347A NO320141B1 (no) | 1999-05-03 | 2001-11-01 | 3-deoksy-desmykosinderivater og fremgangsmate for deres fremstilling |
| BG106172A BG106172A (bg) | 1999-05-03 | 2001-12-03 | 3-дезокси-десмикозинови производни и метод за тяхното получаване |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HR990129A HRP990129B1 (en) | 1999-05-03 | 1999-05-03 | New compounds of 3-deoxy-desmycosin class and process for the preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP990129A2 HRP990129A2 (en) | 2001-12-31 |
| HRP990129B1 true HRP990129B1 (en) | 2003-10-31 |
Family
ID=10946915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR990129A HRP990129B1 (en) | 1999-03-05 | 1999-05-03 | New compounds of 3-deoxy-desmycosin class and process for the preparation thereof |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6504035B1 (cs) |
| EP (1) | EP1175428B1 (cs) |
| JP (1) | JP2002543212A (cs) |
| KR (1) | KR100679903B1 (cs) |
| CN (1) | CN1191263C (cs) |
| AT (1) | ATE238332T1 (cs) |
| AU (1) | AU767549B2 (cs) |
| BG (1) | BG106172A (cs) |
| BR (1) | BR0010250A (cs) |
| CA (1) | CA2368249A1 (cs) |
| CZ (1) | CZ296455B6 (cs) |
| DE (1) | DE60002314T2 (cs) |
| DK (1) | DK1175428T3 (cs) |
| EA (1) | EA004059B1 (cs) |
| EE (1) | EE04594B1 (cs) |
| ES (1) | ES2198302T3 (cs) |
| GE (1) | GEP20032927B (cs) |
| HK (1) | HK1050010A1 (cs) |
| HR (1) | HRP990129B1 (cs) |
| HU (1) | HUP0201140A3 (cs) |
| IL (1) | IL145989A0 (cs) |
| IS (1) | IS6117A (cs) |
| MX (1) | MXPA01011089A (cs) |
| NO (1) | NO320141B1 (cs) |
| NZ (1) | NZ515280A (cs) |
| PL (1) | PL352027A1 (cs) |
| SK (1) | SK283967B6 (cs) |
| TR (1) | TR200103146T2 (cs) |
| UA (1) | UA66927C2 (cs) |
| WO (1) | WO2000066602A1 (cs) |
| ZA (1) | ZA200108482B (cs) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8405087D0 (en) * | 1984-02-27 | 1984-04-04 | Omura S | Antibiotic |
| GB2171991B (en) * | 1985-03-06 | 1988-08-17 | Satoshi Omura | Novel macrolide derivatives, process for preparing same, and antibacterial compositions thereof |
| JPS62221695A (ja) * | 1986-03-24 | 1987-09-29 | Microbial Chem Res Found | タイロシンオキシム誘導体およびその製造法 |
| YU45033B (en) * | 1987-04-14 | 1991-06-30 | Pliva Zagreb | Process for preparing 10,11,12,13-tetrahydro derivative |
| JPH05230094A (ja) * | 1992-02-26 | 1993-09-07 | Asahi Chem Ind Co Ltd | マイシナマイシン誘導体 |
-
1999
- 1999-05-03 HR HR990129A patent/HRP990129B1/xx not_active IP Right Cessation
-
2000
- 2000-05-02 IL IL14598900A patent/IL145989A0/xx unknown
- 2000-05-02 KR KR1020017014045A patent/KR100679903B1/ko not_active Expired - Fee Related
- 2000-05-02 UA UA2001118220A patent/UA66927C2/uk unknown
- 2000-05-02 CA CA002368249A patent/CA2368249A1/en not_active Abandoned
- 2000-05-02 PL PL00352027A patent/PL352027A1/xx not_active IP Right Cessation
- 2000-05-02 HU HU0201140A patent/HUP0201140A3/hu unknown
- 2000-05-02 AT AT00920939T patent/ATE238332T1/de not_active IP Right Cessation
- 2000-05-02 AU AU41349/00A patent/AU767549B2/en not_active Ceased
- 2000-05-02 ES ES00920939T patent/ES2198302T3/es not_active Expired - Lifetime
- 2000-05-02 NZ NZ515280A patent/NZ515280A/xx unknown
- 2000-05-02 EP EP00920939A patent/EP1175428B1/en not_active Expired - Lifetime
- 2000-05-02 WO PCT/HR2000/000012 patent/WO2000066602A1/en active Search and Examination
- 2000-05-02 EA EA200101169A patent/EA004059B1/ru not_active IP Right Cessation
- 2000-05-02 GE GEAP20006228A patent/GEP20032927B/en unknown
- 2000-05-02 MX MXPA01011089A patent/MXPA01011089A/es active IP Right Grant
- 2000-05-02 TR TR2001/03146T patent/TR200103146T2/xx unknown
- 2000-05-02 DE DE60002314T patent/DE60002314T2/de not_active Expired - Lifetime
- 2000-05-02 HK HK03100593.8A patent/HK1050010A1/zh unknown
- 2000-05-02 EE EEP200100571A patent/EE04594B1/xx not_active IP Right Cessation
- 2000-05-02 BR BR0010250-4A patent/BR0010250A/pt not_active IP Right Cessation
- 2000-05-02 DK DK00920939T patent/DK1175428T3/da active
- 2000-05-02 SK SK1568-2001A patent/SK283967B6/sk not_active IP Right Cessation
- 2000-05-02 US US09/959,692 patent/US6504035B1/en not_active Expired - Fee Related
- 2000-05-02 CZ CZ20013821A patent/CZ296455B6/cs not_active IP Right Cessation
- 2000-05-02 CN CNB008071519A patent/CN1191263C/zh not_active Expired - Fee Related
- 2000-05-02 JP JP2000615631A patent/JP2002543212A/ja active Pending
-
2001
- 2001-10-16 ZA ZA200108482A patent/ZA200108482B/xx unknown
- 2001-10-19 IS IS6117A patent/IS6117A/is unknown
- 2001-11-01 NO NO20015347A patent/NO320141B1/no unknown
- 2001-12-03 BG BG106172A patent/BG106172A/bg unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| B1PR | Patent granted | ||
| PNAN | Change of the applicant name, address/residence |
Owner name: GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O., |
|
| PPPP | Transfer of rights |
Owner name: PLIVA-ISTRAZIVACKI INSTITUT D.O.O., HR |
|
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20080421 Year of fee payment: 10 |
|
| PBON | Lapse due to non-payment of renewal fee |
Effective date: 20091029 |