HRP20150819T1 - Derivati metastina i njihova uporaba - Google Patents

Derivati metastina i njihova uporaba Download PDF

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Publication number
HRP20150819T1
HRP20150819T1 HRP20150819TT HRP20150819T HRP20150819T1 HR P20150819 T1 HRP20150819 T1 HR P20150819T1 HR P20150819T T HRP20150819T T HR P20150819TT HR P20150819 T HRP20150819 T HR P20150819T HR P20150819 T1 HRP20150819 T1 HR P20150819T1
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HR
Croatia
Prior art keywords
salt
compound according
leu
glyψ
hyp
Prior art date
Application number
HRP20150819TT
Other languages
English (en)
Croatian (hr)
Inventor
Taiji Asami
Naoki Nishizawa
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of HRP20150819T1 publication Critical patent/HRP20150819T1/hr

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Pregnancy & Childbirth (AREA)
HRP20150819TT 2006-10-25 2007-10-24 Derivati metastina i njihova uporaba HRP20150819T1 (hr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2006290536 2006-10-25
JP2007021387 2007-01-31
JP2007221911 2007-08-28
PCT/JP2007/071169 WO2008050897A1 (en) 2006-10-25 2007-10-24 Metastin derivatives and use thereof
EP20070830903 EP2081955B1 (en) 2006-10-25 2007-10-24 Metastin derivatives and use thereof

Publications (1)

Publication Number Publication Date
HRP20150819T1 true HRP20150819T1 (hr) 2015-09-11

Family

ID=38925530

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20150819TT HRP20150819T1 (hr) 2006-10-25 2007-10-24 Derivati metastina i njihova uporaba

Country Status (33)

Country Link
US (2) US8765909B2 (OSRAM)
EP (1) EP2081955B1 (OSRAM)
JP (2) JP2010507565A (OSRAM)
KR (1) KR101424306B1 (OSRAM)
AR (1) AR063367A1 (OSRAM)
AU (1) AU2007309969B2 (OSRAM)
BR (1) BRPI0717441B8 (OSRAM)
CA (1) CA2667537C (OSRAM)
CL (1) CL2007003053A1 (OSRAM)
CR (1) CR10799A (OSRAM)
CY (1) CY1116627T1 (OSRAM)
DK (1) DK2081955T3 (OSRAM)
EC (1) ECSP099279A (OSRAM)
ES (1) ES2539430T3 (OSRAM)
GE (1) GEP20125568B (OSRAM)
HR (1) HRP20150819T1 (OSRAM)
HU (1) HUE025291T2 (OSRAM)
IL (1) IL198046A (OSRAM)
JO (1) JO3048B1 (OSRAM)
MA (1) MA30887B1 (OSRAM)
ME (1) ME00786B (OSRAM)
MX (1) MX2009004148A (OSRAM)
MY (1) MY145975A (OSRAM)
NO (1) NO341584B1 (OSRAM)
NZ (1) NZ576375A (OSRAM)
PE (1) PE20081469A1 (OSRAM)
PL (1) PL2081955T3 (OSRAM)
PT (1) PT2081955E (OSRAM)
RS (1) RS54083B1 (OSRAM)
SI (1) SI2081955T1 (OSRAM)
TN (1) TN2009000140A1 (OSRAM)
TW (1) TWI404726B (OSRAM)
WO (1) WO2008050897A1 (OSRAM)

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WO2004063221A1 (ja) 2002-12-26 2004-07-29 Takeda Pharmaceutical Company Limited メタスチン誘導体およびその用途
PE20091567A1 (es) * 2004-06-25 2009-11-03 Takeda Pharmaceutical Derivados de metastina en el tratamiento del cancer
US20090093615A1 (en) * 2005-12-22 2009-04-09 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US20090099334A1 (en) * 2005-12-22 2009-04-16 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US8404643B2 (en) 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
TWI386417B (zh) 2005-12-22 2013-02-21 Takeda Pharmaceutical 轉移抑素衍生物及其用途
WO2007125619A1 (ja) * 2006-04-26 2007-11-08 Kyoto University Gpr54アゴニスト活性を有する新規化合物
TWI404726B (zh) 2006-10-25 2013-08-11 Takeda Pharmaceutical 腫瘤轉移抑制素衍生物及其用途
US8110639B2 (en) * 2006-11-17 2012-02-07 Solvay Advanced Polymers, L.L.C. Transparent and flame retardant polysulfone compositions
US20110118172A1 (en) * 2008-04-24 2011-05-19 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
EP2275433B1 (en) * 2008-04-30 2017-06-07 Kyoto University Metastin derivative and use thereof
ES2617657T3 (es) 2008-07-30 2017-06-19 Takeda Pharmaceutical Company Limited Derivado de metastina y uso del mismo
WO2010137022A1 (en) * 2009-05-27 2010-12-02 Yeda Research And Development Co. Ltd Gpr54 agonists or antagonists for treatment of diseases presenting behavioral abnormalities
KR20130097088A (ko) * 2010-06-25 2013-09-02 다케다 야쿠힌 고교 가부시키가이샤 서방성 제제
EP2755690B1 (en) 2011-08-04 2020-04-01 Merck Sharp & Dohme B.V. Kisspeptide-pentasaccharide conjugates
US10202418B2 (en) 2013-06-12 2019-02-12 Merck Patent Gmbh Hydroxy-ethylene derivatives for the treatment of arthrosis
WO2015112703A1 (en) * 2014-01-22 2015-07-30 The Johns Hopkins University Compositions and methods for treating diabetes
JP6253146B2 (ja) * 2014-02-04 2017-12-27 国立大学法人山口大学 新規なペプチド誘導体及びこれを含有する医薬
EP3253774B1 (en) * 2015-02-08 2018-11-21 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Peptides for the treatment of malignant proliferative diseases
JP7215755B2 (ja) * 2017-07-05 2023-01-31 エックスディーシーエクスプローラー (シャンハイ) カンパニー リミテッド ペプチド類化合物、その使用及びそれを含む組成物
TWI795462B (zh) * 2017-11-17 2023-03-11 日商鹽野義製藥股份有限公司 光安定性及溶出性優異的醫藥製劑
CA3179884A1 (en) * 2020-04-08 2021-10-14 Rutgers, The State University Of New Jersey Modified kisspeptin receptor agonists for fatty liver disease

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