HRP20130202T1 - Spojevi imidazo[1,2-a] pirazina za lijeäśenje virusnih infekcija kao što je hepatitis - Google Patents

Spojevi imidazo[1,2-a] pirazina za lijeäśenje virusnih infekcija kao što je hepatitis Download PDF

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Publication number
HRP20130202T1
HRP20130202T1 HRP20130202AT HRP20130202T HRP20130202T1 HR P20130202 T1 HRP20130202 T1 HR P20130202T1 HR P20130202A T HRP20130202A T HR P20130202AT HR P20130202 T HRP20130202 T HR P20130202T HR P20130202 T1 HRP20130202 T1 HR P20130202T1
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HR
Croatia
Prior art keywords
compound according
och3
halogen
alkyl
nhcor8
Prior art date
Application number
HRP20130202AT
Other languages
English (en)
Croatian (hr)
Inventor
Angus Macleod
Dale Robert Mitchell
Nicholas John Palmer
Christophe Claude Parsy
Michael Daniel Goldsmith
Clifford John Harris
Original Assignee
Biofocus Dpi Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biofocus Dpi Limited filed Critical Biofocus Dpi Limited
Publication of HRP20130202T1 publication Critical patent/HRP20130202T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HRP20130202AT 2007-08-21 2008-08-20 Spojevi imidazo[1,2-a] pirazina za lijeäśenje virusnih infekcija kao što je hepatitis HRP20130202T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0716292.8A GB0716292D0 (en) 2007-08-21 2007-08-21 Imidazopyrazine compounds
PCT/EP2008/060896 WO2009024585A2 (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis

Publications (1)

Publication Number Publication Date
HRP20130202T1 true HRP20130202T1 (hr) 2013-04-30

Family

ID=38566736

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20130202AT HRP20130202T1 (hr) 2007-08-21 2008-08-20 Spojevi imidazo[1,2-a] pirazina za lijeäśenje virusnih infekcija kao što je hepatitis

Country Status (20)

Country Link
US (1) US8362018B2 (enExample)
EP (2) EP2567960A3 (enExample)
JP (1) JP2010536825A (enExample)
KR (1) KR20100081294A (enExample)
CN (1) CN101835780B (enExample)
AU (1) AU2008290531A1 (enExample)
BR (1) BRPI0815717A2 (enExample)
CA (1) CA2707521A1 (enExample)
CY (1) CY1113872T1 (enExample)
DK (1) DK2193131T3 (enExample)
ES (1) ES2404415T3 (enExample)
GB (1) GB0716292D0 (enExample)
HR (1) HRP20130202T1 (enExample)
MX (1) MX2010001733A (enExample)
NZ (1) NZ584108A (enExample)
PL (1) PL2193131T3 (enExample)
PT (1) PT2193131E (enExample)
SI (1) SI2193131T1 (enExample)
WO (1) WO2009024585A2 (enExample)
ZA (1) ZA201002009B (enExample)

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HRP20210403T1 (hr) 2015-04-29 2021-10-29 Janssen Pharmaceutica Nv Azabenzimidazoli i njihova uporaba kao modulatora ampa receptora
WO2016206999A1 (en) * 2015-06-24 2016-12-29 Apodemus Ab Pyrazolo[1,5-a]triazin-4-amine derivatives useful in therapy
JP6507976B2 (ja) * 2015-09-30 2019-05-08 東レ株式会社 イミダゾール−２−カルボン酸エステル誘導体又はその塩の製造方法
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HK1250945A1 (zh) * 2016-03-31 2019-01-18 罗马克实验室有限公司 用於治疗病毒性感染的噻唑化物化合物
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TW201817714A (zh) 2016-08-30 2018-05-16 英商葛蘭素史密斯克藍智慧財產權有限公司 抑制3c及3cl蛋白酶之化合物及其使用方法
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JP7309725B2 (ja) 2018-08-21 2023-07-18 杏林製薬株式会社 ２環性ヘテロ芳香環誘導体
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CN109369545B (zh) * 2018-12-14 2020-04-10 东营曜康医药科技有限公司 2-甲基-5-甲酸吡嗪的合成工艺
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JP7824232B2 (ja) * 2020-06-01 2026-03-04 エフ． ホフマン－ラ ロシュ アーゲー 新規イミダゾピラジン誘導体
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CN113831255B (zh) * 2021-11-25 2022-03-11 山东诚创蓝海医药科技有限公司 一种2-氨基丙二酰胺的制备方法
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Also Published As

Publication number Publication date
BRPI0815717A2 (pt) 2015-02-10
DK2193131T3 (da) 2013-04-22
ES2404415T3 (es) 2013-05-27
CY1113872T1 (el) 2016-07-27
KR20100081294A (ko) 2010-07-14
EP2193131B1 (en) 2013-01-30
HK1143810A1 (en) 2011-01-14
SI2193131T1 (sl) 2013-06-28
CA2707521A1 (en) 2009-02-26
EP2567960A3 (en) 2013-06-05
PL2193131T3 (pl) 2013-07-31
CN101835780A (zh) 2010-09-15
NZ584108A (en) 2012-06-29
MX2010001733A (es) 2010-07-06
WO2009024585A3 (en) 2009-08-06
AU2008290531A1 (en) 2009-02-26
WO2009024585A2 (en) 2009-02-26
US8362018B2 (en) 2013-01-29
EP2567960A2 (en) 2013-03-13
JP2010536825A (ja) 2010-12-02
CN101835780B (zh) 2013-09-18
ZA201002009B (en) 2010-12-29
EP2193131A2 (en) 2010-06-09
PT2193131E (pt) 2013-04-04
GB0716292D0 (en) 2007-09-26
US20110166147A1 (en) 2011-07-07

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