GB0716292D0 - Imidazopyrazine compounds - Google Patents

Imidazopyrazine compounds

Info

Publication number
GB0716292D0
GB0716292D0 GBGB0716292.8A GB0716292A GB0716292D0 GB 0716292 D0 GB0716292 D0 GB 0716292D0 GB 0716292 A GB0716292 A GB 0716292A GB 0716292 D0 GB0716292 D0 GB 0716292D0
Authority
GB
United Kingdom
Prior art keywords
imidazopyrazine compounds
imidazopyrazine
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0716292.8A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biofocus DPI Ltd
Original Assignee
Biofocus DPI Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biofocus DPI Ltd filed Critical Biofocus DPI Ltd
Priority to GBGB0716292.8A priority Critical patent/GB0716292D0/en
Publication of GB0716292D0 publication Critical patent/GB0716292D0/en
Priority to DK08787346.9T priority patent/DK2193131T3/da
Priority to AU2008290531A priority patent/AU2008290531A1/en
Priority to EP08787346A priority patent/EP2193131B1/en
Priority to KR1020107005549A priority patent/KR20100081294A/ko
Priority to ES08787346T priority patent/ES2404415T3/es
Priority to PL08787346T priority patent/PL2193131T3/pl
Priority to SI200830948T priority patent/SI2193131T1/sl
Priority to PT87873469T priority patent/PT2193131E/pt
Priority to HK10110351.0A priority patent/HK1143810B/en
Priority to BRPI0815717-0A2A priority patent/BRPI0815717A2/pt
Priority to MX2010001733A priority patent/MX2010001733A/es
Priority to JP2010521417A priority patent/JP2010536825A/ja
Priority to NZ584108A priority patent/NZ584108A/en
Priority to CA2707521A priority patent/CA2707521A1/en
Priority to HRP20130202AT priority patent/HRP20130202T1/hr
Priority to CN2008801108961A priority patent/CN101835780B/zh
Priority to EP12188861.4A priority patent/EP2567960A3/en
Priority to PCT/EP2008/060896 priority patent/WO2009024585A2/en
Priority to US12/674,525 priority patent/US8362018B2/en
Priority to ZA2010/02009A priority patent/ZA201002009B/en
Priority to CY20131100277T priority patent/CY1113872T1/el
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GBGB0716292.8A 2007-08-21 2007-08-21 Imidazopyrazine compounds Ceased GB0716292D0 (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
GBGB0716292.8A GB0716292D0 (en) 2007-08-21 2007-08-21 Imidazopyrazine compounds
US12/674,525 US8362018B2 (en) 2007-08-21 2008-08-20 Substituted imidazo[1,2-a]pyrazine compounds useful for the treatment of viral infections
BRPI0815717-0A2A BRPI0815717A2 (pt) 2007-08-21 2008-08-20 Compostos de imidazopirazina.
JP2010521417A JP2010536825A (ja) 2007-08-21 2008-08-20 肝炎などのウイルス感染の治療用イミダゾ［１，２−ａ］ピラジン化合物
EP08787346A EP2193131B1 (en) 2007-08-21 2008-08-20 Imidazo[1,2-a]pyrazine compounds for treatment of viral infections such as hepatitis
KR1020107005549A KR20100081294A (ko) 2007-08-21 2008-08-20 간염과 같은 바이러스성 감염 치료용 이미다조[1,2-ａ] 피라진 화합물
ES08787346T ES2404415T3 (es) 2007-08-21 2008-08-20 Compuestos de imidazo[1,2-a]pirazina para el tratamiento de infecciones virales tales como la hepatitis
PL08787346T PL2193131T3 (pl) 2007-08-21 2008-08-20 Związki imidazo[1,2-a]pirazyny w leczeniu infekcji wirusowych takich jak zapalenia wątroby
SI200830948T SI2193131T1 (sl) 2007-08-21 2008-08-20 Imidazo(1,2-A)pirazin spojine za zdravljenje virusnih okuĹľb kot je hepatitis
PT87873469T PT2193131E (pt) 2007-08-21 2008-08-20 Compostos de imidazol[1,2-a]pirazina para o tratamento de infecções virais tais como a hepatite
HK10110351.0A HK1143810B (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis
DK08787346.9T DK2193131T3 (da) 2007-08-21 2008-08-20 Imidazo[1,2-a]pyrazinforbindelser til behandling af virusinfektioner såsom hepatitis
MX2010001733A MX2010001733A (es) 2007-08-21 2008-08-20 Compustos de imidazo[1,2-a]pirazina para tratamiento de infecciones virales tales como hepatitis.
AU2008290531A AU2008290531A1 (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis
NZ584108A NZ584108A (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis
CA2707521A CA2707521A1 (en) 2007-08-21 2008-08-20 Imidazopyrazine compounds
HRP20130202AT HRP20130202T1 (hr) 2007-08-21 2008-08-20 Spojevi imidazo[1,2-a] pirazina za lijeäśenje virusnih infekcija kao što je hepatitis
CN2008801108961A CN101835780B (zh) 2007-08-21 2008-08-20 用于治疗病毒感染诸如肝炎的咪唑并[1,2-a]吡嗪化合物
EP12188861.4A EP2567960A3 (en) 2007-08-21 2008-08-20 Imidazo[1,2-a]pyrazine compounds for treatment of viral infections such as hepatitis
PCT/EP2008/060896 WO2009024585A2 (en) 2007-08-21 2008-08-20 Imidazo [1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis
ZA2010/02009A ZA201002009B (en) 2007-08-21 2010-03-19 Imidazo[1,2-a] pyrazine compounds for treatment of viral infections such as hepatitis
CY20131100277T CY1113872T1 (el) 2007-08-21 2013-04-03 Ενωσεις imidazo[1,2-a]pyrazine για την θεραπεια μολυνσεων απο ιους οπως ηπατιτιδα

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0716292.8A GB0716292D0 (en) 2007-08-21 2007-08-21 Imidazopyrazine compounds

Publications (1)

Publication Number Publication Date
GB0716292D0 true GB0716292D0 (en) 2007-09-26

Family

ID=38566736

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0716292.8A Ceased GB0716292D0 (en) 2007-08-21 2007-08-21 Imidazopyrazine compounds

Country Status (20)

Country Link
US (1) US8362018B2 (enExample)
EP (2) EP2567960A3 (enExample)
JP (1) JP2010536825A (enExample)
KR (1) KR20100081294A (enExample)
CN (1) CN101835780B (enExample)
AU (1) AU2008290531A1 (enExample)
BR (1) BRPI0815717A2 (enExample)
CA (1) CA2707521A1 (enExample)
CY (1) CY1113872T1 (enExample)
DK (1) DK2193131T3 (enExample)
ES (1) ES2404415T3 (enExample)
GB (1) GB0716292D0 (enExample)
HR (1) HRP20130202T1 (enExample)
MX (1) MX2010001733A (enExample)
NZ (1) NZ584108A (enExample)
PL (1) PL2193131T3 (enExample)
PT (1) PT2193131E (enExample)
SI (1) SI2193131T1 (enExample)
WO (1) WO2009024585A2 (enExample)
ZA (1) ZA201002009B (enExample)

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EP2285783B1 (en) 2008-04-29 2014-05-21 Boehringer Ingelheim International GmbH Indazole compounds as ccr1 receptor antagonists
WO2009137338A1 (en) 2008-05-06 2009-11-12 Boehringer Ingelheim International Gmbh Pyrazole compounds as ccr1 antagonists
JP5507567B2 (ja) 2008-09-26 2014-05-28 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｃｒ１受容体拮抗薬としてのアザインダゾール化合物
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PL2491028T3 (pl) 2009-10-21 2014-05-30 Boehringer Ingelheim Int Związki indazolowe i pirazolopirydynowe jako antagoniści receptora CCR1
US8927550B2 (en) 2009-10-27 2015-01-06 Boehringer Ingelheim International Gmbh Heterocyclic compounds as CCR1 receptor antagonists
CA2778949C (en) 2009-10-30 2018-02-27 Janssen Pharmaceutica Nv Imidazo[1,2-b]pyridazine derivatives and their use as pde10 inhibitors
WO2011071730A1 (en) * 2009-12-08 2011-06-16 Boehringer Ingelheim International Gmbh Process for synthesis of intermediates useful for making substituted indazole and azaindazole compounds
AR080754A1 (es) 2010-03-09 2012-05-09 Janssen Pharmaceutica Nv Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
ES2551407T3 (es) * 2010-03-18 2015-11-18 Bayer Intellectual Property Gmbh Imidazopirazinas
JP5793182B2 (ja) 2010-04-30 2015-10-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｃｃｒ１受容体アンタゴニストとしてのアザインダゾールアミド化合物
WO2011151259A1 (en) 2010-06-01 2011-12-08 Bayer Pharma Aktiengesellschaft Substituted imidazopyrazines
CA2821819A1 (en) 2010-12-17 2012-06-21 Marcus Koppitz 6-substituted imidazopyrazines for use as mps-1 and tkk inhibitors in the treatment of hyperproliferative disorders
EP2651944B1 (en) * 2010-12-17 2015-09-23 Bayer Intellectual Property GmbH Substituted 6-imidazopyrazines for use as mps-1 and tkk inhibitors in the treatment of hyperproliferative disorders
WO2012080228A1 (en) 2010-12-17 2012-06-21 Bayer Pharma Aktiengesellschaft 6-thio-substituted imidazopyrazines for use as mps-1 and tkk inhibitors in the treatment of hyperproliferative disorders
CN103429591A (zh) 2010-12-17 2013-12-04 拜耳知识产权有限责任公司 在治疗过度增殖性病症中用作mps-1和tkk抑制剂的6-取代的咪唑并吡嗪
CA2821829A1 (en) * 2010-12-17 2012-06-21 Bayer Intellectual Property Gmbh Imidazopyrazines for use as mps-1 and tkk inhibitors in the treatment of hyperproliferative disorders
ES2544609T3 (es) * 2010-12-17 2015-09-02 Bayer Intellectual Property Gmbh Imidazopirazinas 2-sustituidas para uso como inhibidores de Mps-1 y TTK en el tratamiento de trastornos hiper-proliferativos
US8546442B2 (en) 2010-12-23 2013-10-01 Boehringer Ingelheim International Gmbh Pyrazolopiperidine compounds as CCR1 receptor antagonists
GB201109763D0 (en) * 2011-06-10 2011-07-27 Ucl Business Plc Compounds
BR112013033375B1 (pt) 2011-06-27 2022-05-10 Janssen Pharmaceutica N.V Derivados de 1-aril-4-metil-[1,2,4]triazolo[4,3-a]quinoxa-lina, seu uso, composição farmacêutica que os compreende, processo de preparação dos mesmos, solução estéril e composto intermediário
CA2853221A1 (en) 2011-10-24 2013-05-02 Tohru Yamashita Bicyclic compound
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HRP20210403T1 (hr) 2015-04-29 2021-10-29 Janssen Pharmaceutica Nv Azabenzimidazoli i njihova uporaba kao modulatora ampa receptora
WO2016206999A1 (en) * 2015-06-24 2016-12-29 Apodemus Ab Pyrazolo[1,5-a]triazin-4-amine derivatives useful in therapy
JP6507976B2 (ja) * 2015-09-30 2019-05-08 東レ株式会社 イミダゾール−２−カルボン酸エステル誘導体又はその塩の製造方法
TWI744256B (zh) 2015-11-06 2021-11-01 美商英塞特公司 作為ＰＩ３Ｋ-γ抑制劑之雜環化合物
TW201734003A (zh) 2016-01-05 2017-10-01 英塞特公司 作為ＰＩ３Ｋ-γ抑制劑之吡啶及嘧啶化合物
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CN109369545B (zh) * 2018-12-14 2020-04-10 东营曜康医药科技有限公司 2-甲基-5-甲酸吡嗪的合成工艺
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JP7824232B2 (ja) * 2020-06-01 2026-03-04 エフ． ホフマン－ラ ロシュ アーゲー 新規イミダゾピラジン誘導体
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CN113831255B (zh) * 2021-11-25 2022-03-11 山东诚创蓝海医药科技有限公司 一种2-氨基丙二酰胺的制备方法
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Also Published As

Publication number Publication date
BRPI0815717A2 (pt) 2015-02-10
DK2193131T3 (da) 2013-04-22
ES2404415T3 (es) 2013-05-27
CY1113872T1 (el) 2016-07-27
KR20100081294A (ko) 2010-07-14
EP2193131B1 (en) 2013-01-30
HK1143810A1 (en) 2011-01-14
SI2193131T1 (sl) 2013-06-28
CA2707521A1 (en) 2009-02-26
EP2567960A3 (en) 2013-06-05
PL2193131T3 (pl) 2013-07-31
CN101835780A (zh) 2010-09-15
NZ584108A (en) 2012-06-29
MX2010001733A (es) 2010-07-06
WO2009024585A3 (en) 2009-08-06
AU2008290531A1 (en) 2009-02-26
WO2009024585A2 (en) 2009-02-26
US8362018B2 (en) 2013-01-29
EP2567960A2 (en) 2013-03-13
JP2010536825A (ja) 2010-12-02
CN101835780B (zh) 2013-09-18
ZA201002009B (en) 2010-12-29
EP2193131A2 (en) 2010-06-09
PT2193131E (pt) 2013-04-04
US20110166147A1 (en) 2011-07-07
HRP20130202T1 (hr) 2013-04-30

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)