HRP20100631T1 - Kristal indola koji sadrži sulfonamid i postupak njegove proizvodnje - Google Patents

Kristal indola koji sadrži sulfonamid i postupak njegove proizvodnje Download PDF

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Publication number
HRP20100631T1
HRP20100631T1 HR20100631T HRP20100631T HRP20100631T1 HR P20100631 T1 HRP20100631 T1 HR P20100631T1 HR 20100631 T HR20100631 T HR 20100631T HR P20100631 T HRP20100631 T HR P20100631T HR P20100631 T1 HRP20100631 T1 HR P20100631T1
Authority
HR
Croatia
Prior art keywords
indol
cyano
methyl
sulfonamide
crystalline form
Prior art date
Application number
HR20100631T
Other languages
English (en)
Croatian (hr)
Inventor
Takahashi Keiko
Hayashi Kenji
Abe Taichi
Omae Takao
Kato Takashi
Original Assignee
Eisai R&D Management Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Management Co. filed Critical Eisai R&D Management Co.
Publication of HRP20100631T1 publication Critical patent/HRP20100631T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR20100631T 2003-09-10 2004-09-01 Kristal indola koji sadrži sulfonamid i postupak njegove proizvodnje HRP20100631T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003318953 2003-09-10
PCT/JP2004/012649 WO2005026118A1 (ja) 2003-09-10 2004-09-01 スルホンアミド含有インドール化合物の結晶およびその製造方法

Publications (1)

Publication Number Publication Date
HRP20100631T1 true HRP20100631T1 (hr) 2010-12-31

Family

ID=34308544

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100631T HRP20100631T1 (hr) 2003-09-10 2004-09-01 Kristal indola koji sadrži sulfonamid i postupak njegove proizvodnje

Country Status (24)

Country Link
US (2) US7754894B2 (https=)
EP (1) EP1666463B1 (https=)
JP (1) JP4435090B2 (https=)
KR (1) KR20060120644A (https=)
CN (2) CN101165049A (https=)
AT (1) ATE486849T1 (https=)
AU (1) AU2004272400B2 (https=)
BR (1) BRPI0414314A (https=)
CA (1) CA2536995C (https=)
CY (1) CY1110975T1 (https=)
DE (1) DE602004029907D1 (https=)
DK (1) DK1666463T3 (https=)
ES (1) ES2354286T3 (https=)
HR (1) HRP20100631T1 (https=)
IL (2) IL174059A0 (https=)
MX (1) MXPA06002732A (https=)
NO (1) NO335256B1 (https=)
NZ (1) NZ546111A (https=)
PL (1) PL1666463T3 (https=)
PT (1) PT1666463E (https=)
RU (1) RU2336269C2 (https=)
SI (1) SI1666463T1 (https=)
TW (1) TW200514770A (https=)
WO (1) WO2005026118A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1666463T3 (da) * 2003-09-10 2010-12-20 Eisai R&D Man Co Ltd Krystal af sulfonamidholdig indolforbindelse og fremgangsmåde til fremstilling deraf

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3868534B2 (ja) 1996-05-24 2007-01-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド誘導体の製造法および中間体
JP2000247949A (ja) 1999-02-26 2000-09-12 Eisai Co Ltd スルホンアミド含有インドール化合物
WO2001056607A1 (en) * 2000-02-03 2001-08-09 Eisai Co., Ltd. Integrin expression inhibitors
TWI283575B (en) * 2000-10-31 2007-07-11 Eisai Co Ltd Medicinal compositions for concomitant use as anticancer agent
DK1666463T3 (da) * 2003-09-10 2010-12-20 Eisai R&D Man Co Ltd Krystal af sulfonamidholdig indolforbindelse og fremgangsmåde til fremstilling deraf

Also Published As

Publication number Publication date
EP1666463A4 (en) 2007-12-12
NO20061545L (no) 2006-06-09
PL1666463T3 (pl) 2011-04-29
WO2005026118A1 (ja) 2005-03-24
NZ546111A (en) 2008-11-28
BRPI0414314A (pt) 2006-10-31
MXPA06002732A (es) 2006-06-05
AU2004272400A1 (en) 2005-03-24
SI1666463T1 (sl) 2011-02-28
TW200514770A (en) 2005-05-01
IL196569A0 (en) 2011-07-31
US7754894B2 (en) 2010-07-13
RU2006111454A (ru) 2006-08-27
CN1849305A (zh) 2006-10-18
PT1666463E (pt) 2011-01-17
HK1092796A1 (en) 2007-02-16
CA2536995C (en) 2013-12-17
CN100406440C (zh) 2008-07-30
IL174059A0 (en) 2006-08-01
ATE486849T1 (de) 2010-11-15
AU2004272400B2 (en) 2010-03-04
DE602004029907D1 (de) 2010-12-16
CN101165049A (zh) 2008-04-23
KR20060120644A (ko) 2006-11-27
TWI349663B (https=) 2011-10-01
ES2354286T3 (es) 2011-03-11
US20070082941A1 (en) 2007-04-12
CA2536995A1 (en) 2005-03-24
EP1666463B1 (en) 2010-11-03
DK1666463T3 (da) 2010-12-20
JPWO2005026118A1 (ja) 2007-11-08
EP1666463A1 (en) 2006-06-07
CY1110975T1 (el) 2015-06-11
NO335256B1 (no) 2014-10-27
US20090247768A1 (en) 2009-10-01
RU2336269C2 (ru) 2008-10-20
JP4435090B2 (ja) 2010-03-17

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