AU2004272400B2 - Crystal of sulfonamide-containing indole compound and process for producing the same - Google Patents

Crystal of sulfonamide-containing indole compound and process for producing the same Download PDF

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Publication number
AU2004272400B2
AU2004272400B2 AU2004272400A AU2004272400A AU2004272400B2 AU 2004272400 B2 AU2004272400 B2 AU 2004272400B2 AU 2004272400 A AU2004272400 A AU 2004272400A AU 2004272400 A AU2004272400 A AU 2004272400A AU 2004272400 B2 AU2004272400 B2 AU 2004272400B2
Authority
AU
Australia
Prior art keywords
methyl
cyano
cyanobenzenesulfonamide
indol
crystals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004272400A
Other languages
English (en)
Other versions
AU2004272400A1 (en
Inventor
Taichi Abe
Kenji Hayashi
Takashi Kato
Takao Omae
Keiko Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai R&D Management Co Ltd
Original Assignee
Eisai R&D Management Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Management Co Ltd filed Critical Eisai R&D Management Co Ltd
Publication of AU2004272400A1 publication Critical patent/AU2004272400A1/en
Assigned to EISAI R AND D MANAGEMENT CO., LTD. reassignment EISAI R AND D MANAGEMENT CO., LTD. Request for Assignment Assignors: EISAI CO., LTD.
Application granted granted Critical
Publication of AU2004272400B2 publication Critical patent/AU2004272400B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2004272400A 2003-09-10 2004-09-01 Crystal of sulfonamide-containing indole compound and process for producing the same Ceased AU2004272400B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2003318953 2003-09-10
JP2003-318953 2003-09-10
PCT/JP2004/012649 WO2005026118A1 (ja) 2003-09-10 2004-09-01 スルホンアミド含有インドール化合物の結晶およびその製造方法

Publications (2)

Publication Number Publication Date
AU2004272400A1 AU2004272400A1 (en) 2005-03-24
AU2004272400B2 true AU2004272400B2 (en) 2010-03-04

Family

ID=34308544

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004272400A Ceased AU2004272400B2 (en) 2003-09-10 2004-09-01 Crystal of sulfonamide-containing indole compound and process for producing the same

Country Status (24)

Country Link
US (2) US7754894B2 (https=)
EP (1) EP1666463B1 (https=)
JP (1) JP4435090B2 (https=)
KR (1) KR20060120644A (https=)
CN (2) CN101165049A (https=)
AT (1) ATE486849T1 (https=)
AU (1) AU2004272400B2 (https=)
BR (1) BRPI0414314A (https=)
CA (1) CA2536995C (https=)
CY (1) CY1110975T1 (https=)
DE (1) DE602004029907D1 (https=)
DK (1) DK1666463T3 (https=)
ES (1) ES2354286T3 (https=)
HR (1) HRP20100631T1 (https=)
IL (2) IL174059A0 (https=)
MX (1) MXPA06002732A (https=)
NO (1) NO335256B1 (https=)
NZ (1) NZ546111A (https=)
PL (1) PL1666463T3 (https=)
PT (1) PT1666463E (https=)
RU (1) RU2336269C2 (https=)
SI (1) SI1666463T1 (https=)
TW (1) TW200514770A (https=)
WO (1) WO2005026118A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1666463T3 (da) * 2003-09-10 2010-12-20 Eisai R&D Man Co Ltd Krystal af sulfonamidholdig indolforbindelse og fremgangsmåde til fremstilling deraf

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3868534B2 (ja) 1996-05-24 2007-01-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド誘導体の製造法および中間体
JP2000247949A (ja) 1999-02-26 2000-09-12 Eisai Co Ltd スルホンアミド含有インドール化合物
WO2001056607A1 (en) * 2000-02-03 2001-08-09 Eisai Co., Ltd. Integrin expression inhibitors
TWI283575B (en) * 2000-10-31 2007-07-11 Eisai Co Ltd Medicinal compositions for concomitant use as anticancer agent
DK1666463T3 (da) * 2003-09-10 2010-12-20 Eisai R&D Man Co Ltd Krystal af sulfonamidholdig indolforbindelse og fremgangsmåde til fremstilling deraf

Also Published As

Publication number Publication date
EP1666463A4 (en) 2007-12-12
NO20061545L (no) 2006-06-09
PL1666463T3 (pl) 2011-04-29
WO2005026118A1 (ja) 2005-03-24
NZ546111A (en) 2008-11-28
BRPI0414314A (pt) 2006-10-31
MXPA06002732A (es) 2006-06-05
AU2004272400A1 (en) 2005-03-24
SI1666463T1 (sl) 2011-02-28
TW200514770A (en) 2005-05-01
IL196569A0 (en) 2011-07-31
US7754894B2 (en) 2010-07-13
RU2006111454A (ru) 2006-08-27
CN1849305A (zh) 2006-10-18
PT1666463E (pt) 2011-01-17
HK1092796A1 (en) 2007-02-16
CA2536995C (en) 2013-12-17
CN100406440C (zh) 2008-07-30
IL174059A0 (en) 2006-08-01
ATE486849T1 (de) 2010-11-15
DE602004029907D1 (de) 2010-12-16
CN101165049A (zh) 2008-04-23
KR20060120644A (ko) 2006-11-27
TWI349663B (https=) 2011-10-01
ES2354286T3 (es) 2011-03-11
US20070082941A1 (en) 2007-04-12
CA2536995A1 (en) 2005-03-24
EP1666463B1 (en) 2010-11-03
HRP20100631T1 (hr) 2010-12-31
DK1666463T3 (da) 2010-12-20
JPWO2005026118A1 (ja) 2007-11-08
EP1666463A1 (en) 2006-06-07
CY1110975T1 (el) 2015-06-11
NO335256B1 (no) 2014-10-27
US20090247768A1 (en) 2009-10-01
RU2336269C2 (ru) 2008-10-20
JP4435090B2 (ja) 2010-03-17

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: EISAI R AND D MANAGEMENT CO., LTD.

Free format text: FORMER APPLICANT(S): EISAI CO., LTD.

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired