HRP20080274T3 - 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri - Google Patents

2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri

Info

Publication number
HRP20080274T3
HRP20080274T3 HR20080274T HRP20080274T HRP20080274T3 HR P20080274 T3 HRP20080274 T3 HR P20080274T3 HR 20080274 T HR20080274 T HR 20080274T HR P20080274 T HRP20080274 T HR P20080274T HR P20080274 T3 HRP20080274 T3 HR P20080274T3
Authority
HR
Croatia
Prior art keywords
indolylsulfanyl
ssri
amine derivatives
benzyl amine
benzyl
Prior art date
Application number
HR20080274T
Other languages
English (en)
Croatian (hr)
Inventor
Kehler Jan
Juhl Karsten
Sejberg Jimmy
Bang Norgaard Morten
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of HRP20080274T3 publication Critical patent/HRP20080274T3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/06Anti-spasmodics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR20080274T 2003-12-23 2008-06-19 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri HRP20080274T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53259303P 2003-12-23 2003-12-23
DKPA200301923 2003-12-23
PCT/DK2004/000894 WO2005061455A1 (en) 2003-12-23 2004-12-21 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri

Publications (1)

Publication Number Publication Date
HRP20080274T3 true HRP20080274T3 (en) 2008-12-31

Family

ID=34712442

Family Applications (2)

Application Number Title Priority Date Filing Date
HR20080274T HRP20080274T3 (en) 2003-12-23 2008-06-19 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri
HR20110400T HRP20110400T1 (hr) 2003-12-23 2011-05-27 Derivati 2-(1h-indolilsulfanil)-benzil amina kao ssri

Family Applications After (1)

Application Number Title Priority Date Filing Date
HR20110400T HRP20110400T1 (hr) 2003-12-23 2011-05-27 Derivati 2-(1h-indolilsulfanil)-benzil amina kao ssri

Country Status (18)

Country Link
US (4) US7563908B2 (da)
EP (1) EP1701940B1 (da)
JP (3) JP4090491B2 (da)
AT (1) ATE396970T1 (da)
AU (1) AU2004303461B2 (da)
BR (1) BRPI0417858B1 (da)
CY (2) CY1108230T1 (da)
DE (1) DE602004014190D1 (da)
DK (1) DK1701940T3 (da)
ES (1) ES2303960T3 (da)
HR (2) HRP20080274T3 (da)
IL (1) IL176111A (da)
MX (1) MXPA06007172A (da)
PL (1) PL1701940T3 (da)
PT (1) PT1701940E (da)
RS (1) RS50589B (da)
SI (1) SI1701940T1 (da)
WO (1) WO2005061455A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1701940T3 (pl) * 2003-12-23 2008-11-28 H Lundbeck As Pochodne 2-(1H-indolilosulfanylo)benzyloaminy jako SSRI
AR052308A1 (es) 2004-07-16 2007-03-14 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
AR054394A1 (es) * 2005-06-17 2007-06-20 Lundbeck & Co As H Derivados de 2- (1h-indolilsulfanil)-aril amina
AR054393A1 (es) 2005-06-17 2007-06-20 Lundbeck & Co As H Derivados de benzo(b)furano y benzo(b)tiofeno, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la inhibicion de la reabsorcion de neurotransmisores de amina biogenicos.
US7629473B2 (en) 2005-06-17 2009-12-08 H. Lundbeck A/S 2-(1H-indolylsulfanyl)-aryl amine derivatives
US20090054510A1 (en) * 2006-03-22 2009-02-26 H. Lundbeck A/S Method for identifying compounds for the treatment of depression
TW200819426A (en) 2006-08-31 2008-05-01 Lundbeck & Co As H Novel indane compounds
AU2007302449A1 (en) * 2006-09-28 2008-04-03 H. Lundbeck A/S [2-(6-fluoro-1H-indol-3-ylsulfanyl)benzyl]methyl amine for the treatment of affective disorders
CN101563320B (zh) * 2006-09-28 2012-05-30 H.隆德贝克有限公司 用于治疗情感障碍的[2-(6-氟-1h-吲哚-3-基硫烷基)苄基]甲胺
CN101868233A (zh) * 2007-09-24 2010-10-20 H.隆德贝克有限公司 与血清素双重作用化合物有关的组合疗法
TW200938189A (en) * 2008-03-13 2009-09-16 Lundbeck & Co As H [2-(6-flouro-1H-indol-3-ylsulfanyl)benzyl]methyl amine for the treatment of affective disorders
WO2010006945A1 (en) 2008-07-15 2010-01-21 F. Hoffmann-La Roche Ag Substituted indolyl and indazolyl derivatives and uses thereof
CN103201262B (zh) * 2010-08-20 2016-06-01 艾米拉医药股份有限公司 自分泌运动因子抑制剂及其用途
US9260416B2 (en) 2011-05-27 2016-02-16 Amira Pharmaceuticals, Inc. Heterocyclic autotaxin inhibitors and uses thereof
JP2016530209A (ja) 2013-09-17 2016-09-29 ファーマケア,インク. ビニルオートタキシン阻害剤化合物
EP3046909A4 (en) 2013-09-17 2017-03-29 Pharmakea, Inc. Heterocyclic vinyl autotaxin inhibitor compounds
JP2016531874A (ja) 2013-09-26 2016-10-13 ファーマケア,インク. オートタキシン阻害剤化合物
PT3071561T (pt) 2013-11-22 2021-06-25 Sabre Therapeutics Llc Compostos inibidores de autotaxina
EP4026549A1 (en) 2015-05-27 2022-07-13 Sabre Therapeutics LLC Autotaxin inhibitors and uses thereof
US11339144B2 (en) 2017-04-10 2022-05-24 Navitor Pharmaceuticals, Inc. Heteroaryl Rheb inhibitors and uses thereof

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2003023A (en) * 1930-10-16 1935-05-28 Westinghouse Electric & Mfg Co Mercury vapor or noble gas rectifier with arc control
US3803143A (en) * 1969-09-08 1974-04-09 Eisai Co Ltd 6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines
US4018830A (en) * 1969-09-22 1977-04-19 Merck & Co., Inc. Phenylthioaralkylamines
US4055665A (en) * 1974-11-25 1977-10-25 Merck & Co., Inc. Treating arrythmia with phenylthioaralkylamines
US4056632A (en) * 1975-07-21 1977-11-01 Burroughs Wellcome Co. 2-Hydroxymethyl-2'-aminomethyl-diphenylsulfides and method of use
US4241071A (en) * 1977-01-27 1980-12-23 American Hoechst Corporation Antidepressant (α-phenyl-2-tolyl)azacycloalkanes
US4198417A (en) * 1979-01-10 1980-04-15 American Hoechst Corporation Phenoxyphenylpiperidines
DE3640475A1 (de) 1986-11-27 1988-06-09 Hoechst Sa Lab Arzneimittel auf basis von derivaten des 3,4-diphenylpiperidins, die verwendung der derivate als arzneimittel sowie neue 3,4-diphenylpiperidinderivate und verfahren zu ihrer herstellung
EP0396827A1 (en) 1989-05-09 1990-11-14 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu 2-Phenylthiobenzylamine dervivatives and acid addition salts thereof
GB8912971D0 (en) 1989-06-06 1989-07-26 Wellcome Found Halogen substituted diphenylsulfides
US6645969B1 (en) * 1991-05-10 2003-11-11 Aventis Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
ES2143992T3 (es) 1991-11-25 2000-06-01 Pfizer Derivados de 5-(hetero- o carbociclilamino)-indol, su preparacion y uso como 5-ht1 agonistas.
GB9126311D0 (en) 1991-12-11 1992-02-12 Wellcome Found Substituted diphenylsulfides
GB9226532D0 (en) 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
WO1995029897A1 (en) * 1994-04-29 1995-11-09 G.D. Searle & Co. METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS
EP0755923B1 (en) 1995-01-23 2005-05-04 Daiichi Suntory Pharma Co., Ltd. Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor
EP0907654B1 (en) 1995-11-06 2000-08-02 Dsm N.V. De-esterification process
CZ293595A3 (cs) 1995-11-09 1999-12-15 Farmak A. S. Deriváty N,N-dimethyl-2-(arylthio)benzylaminu, jejich soli, způsoby jejich přípravy a jejich použití v léčivých přípravcích
US5912256A (en) * 1996-06-20 1999-06-15 Eli Lilly And Company Compounds having effects on serotonin-related systems
KR20000035880A (ko) * 1996-08-27 2000-06-26 이곤 이 버그 도파민 d2 효능제 및 5ht1a 리간드로서의 4-아미노에톡시 인돌
US5906078A (en) * 1996-10-09 1999-05-25 Gallagher-Kaiser Corporation Retaining strip for sheet covered enclosures
GB9725953D0 (en) 1997-12-08 1998-02-04 Pfizer Ltd Compounds useful in therapy
DE19756036A1 (de) * 1997-12-17 1999-06-24 Merck Patent Gmbh Amid- und Harnstoffderivate
US6333146B1 (en) * 1999-03-10 2001-12-25 Fuji Photo Film Co., Ltd. Methine compound and silver halide photographic material containing the same
CN1721401A (zh) 1999-04-02 2006-01-18 伊科斯公司 白细胞功能相关抗原与细胞间粘着分子结合的抑制剂及其用途
AU780725B2 (en) 1999-04-30 2005-04-14 Trustees Of The University Of Pennsylvania, The Spect imaging agents for serotonin transporters
AU6621600A (en) 1999-08-04 2001-03-05 Millennium Pharmaceuticals, Inc. Melanocortin-4 receptor binding compounds and methods of use thereof
PL355289A1 (en) * 1999-10-13 2004-04-05 Pfizer Products Inc. Biaryl ether derivatives useful as monoamine reuptake inhibitors
US6410736B1 (en) * 1999-11-29 2002-06-25 Pfizer Inc. Biaryl ether derivatives useful as monoamine reuptake inhibitors
TR200201683T2 (tr) 1999-12-30 2002-12-23 H. Lundbeck A/S İkameli fenil-piperazin türevleri, bunların hazırlanması ve kullanımları
CN1244577C (zh) 1999-12-30 2006-03-08 H.隆德贝克有限公司 4-苯基-1-哌嗪基、-哌啶基和-四氢吡啶基衍生物
ATE261958T1 (de) 1999-12-30 2004-04-15 Lundbeck & Co As H Phenylpiperazinyl-derivate
EP1267868B1 (en) * 2000-02-29 2007-07-18 MediQuest Therapeutics, Inc. Inhibitors of melanocyte tyrosinase as topical skin lighteners
AU2001258771A1 (en) * 2000-05-19 2001-11-26 Takeda Chemical Industries Ltd. -secretase inhibitors
US6455738B1 (en) * 2000-07-13 2002-09-24 Rhodia Chimie Process for the sulfonation of an aromatic compound
WO2002006234A1 (fr) * 2000-07-17 2002-01-24 Takeda Chemical Industries, Ltd. Derives de sulfonate, procede de production et utilisation de ces derives
WO2002015910A1 (en) * 2000-08-18 2002-02-28 Sterix Limited 2-substituted estradiol derivative for inhibiting superoxid dismutase
KR20030059107A (ko) * 2000-09-01 2003-07-07 에프엠씨 코포레이션 살충제로서의 이치환된 벤젠
AU2001288623A1 (en) * 2000-09-05 2002-03-22 Tularik, Inc. Fxr modulators
EP1193268A1 (en) * 2000-09-27 2002-04-03 Applied Research Systems ARS Holding N.V. Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moieties as inhibitors of protein Junkinases
US6852816B2 (en) * 2000-10-06 2005-02-08 Biocompatibles Uk Limited Zwitterionic polymers
EP1578341A2 (en) * 2000-10-11 2005-09-28 Tularik Inc. Modulation of ccr4 function
BR0115296A (pt) 2000-11-14 2003-09-02 Merck Patent Ges Mit Beschonkt Uso de inibidores de recaptação de sorotonina e agonistas de 5ht1a combinados
US6436938B1 (en) * 2001-01-22 2002-08-20 Pfizer Inc. Combination treatment for depression
WO2002062766A2 (en) 2001-02-07 2002-08-15 Millennium Pharmaceuticals, Inc. Melanocortin-4 receptor binding compounds and methods of use thereof
JP4187642B2 (ja) 2001-06-07 2008-11-26 エフ.ホフマン−ラ ロシュ アーゲー 5−ht6受容体親和性を有する新規インドール誘導体
EP1403255A4 (en) * 2001-06-12 2005-04-06 Sumitomo Pharma INHIBITORS OF RHO KINASE
UA81749C2 (uk) 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
US7064139B2 (en) * 2001-10-29 2006-06-20 Uniroyal Chemical Company, Inc. Method for treating retroviral infections
HUP0401924A3 (en) * 2001-11-14 2009-07-28 Schering Corp Cannabinoid receptor ligands, their use and pharmaceutical compositions containing them
MXPA04006119A (es) 2001-12-21 2004-11-01 Lundbeck & Co As H Derivados aminoindano como inhibidores de la absorcion de la serotonina y de la norepinefrina.
ATE371680T1 (de) * 2002-01-16 2007-09-15 Biocompatibles Uk Ltd Polymerkonjugate
US20050261298A1 (en) * 2002-01-18 2005-11-24 David Solow-Cordero Methods of treating conditions associated with an Edg-7 receptor
DE60318267T2 (de) * 2002-03-01 2008-12-11 Fujifilm Corp. Farbphotographisches lichtempfindliches Silberhalogenidmaterial
US7829044B2 (en) * 2002-03-04 2010-11-09 Japan Science And Technology Agency Phosphonamides, process for producing the same, and use thereof
CA2480518C (en) * 2002-03-29 2016-07-19 Massachusetts Institute Of Technology Light emitting device including semiconductor nanocrystals
DE10217006A1 (de) * 2002-04-16 2003-11-06 Merck Patent Gmbh Substituierte Indole
CN1662496A (zh) * 2002-06-19 2005-08-31 先灵公司 大麻素受体激动剂
TW200401641A (en) * 2002-07-18 2004-02-01 Wyeth Corp 1-Heterocyclylalkyl-3-sulfonylindole or-indazole derivatives as 5-hydroxytryptamine-6 ligands
MXPA05002836A (es) * 2002-09-17 2005-05-27 Hoffmann La Roche Indoles 2,4-sustituidos y su uso como moduladores 5-ht6.
JP4327091B2 (ja) * 2002-09-17 2009-09-09 エフ.ホフマン−ラ ロシュ アーゲー 2,7−置換インドール及び5−ht6モジュレーターとしてのその使用
EP1402888A1 (en) * 2002-09-18 2004-03-31 Jerini AG The use of substituted carbocyclic compounds as rotamases inhibitors
US20040266732A1 (en) * 2002-09-20 2004-12-30 Jorge Galvez Therapeutic agents, methods, and treatments
US20060189519A1 (en) * 2002-09-26 2006-08-24 Karl Volz Anti-angiogenic fragments fo pigment epithelium-derived factor (pedf)
US20040137389A1 (en) * 2002-12-19 2004-07-15 Kouta Fukui Heat-developable light-sensitive material
NZ541234A (en) * 2002-12-20 2008-06-30 Amgen Inc Asthma and allergic inflammation modulators
US7189501B2 (en) * 2002-12-27 2007-03-13 Fuji Photo Film Co., Ltd. Silver halide color photographic photosensitive material
DE10300098A1 (de) * 2003-01-07 2004-07-15 Bayer Ag Kupfer-Carben-Komplexe und ihre Verwendung
EP2267049A1 (en) * 2003-02-05 2010-12-29 Biocompatibles UK Limited Block copolymers
AR043633A1 (es) * 2003-03-20 2005-08-03 Schering Corp Ligandos de receptores de canabinoides
EP2258365B1 (en) * 2003-03-28 2013-05-29 Novartis Vaccines and Diagnostics, Inc. Use of organic compounds for immunopotentiation
US7244763B2 (en) * 2003-04-17 2007-07-17 Warner Lambert Company Llc Compounds that modulate PPAR activity and methods of preparation
EP1671962A1 (en) * 2003-10-10 2006-06-21 Ono Pharmaceutical Co., Ltd. Novel fused heterocyclic compound and use thereof
US7229751B2 (en) * 2003-11-20 2007-06-12 Konica Minolta Medical & Graphic, Inc. Silver salt photothermographic dry imaging material and image forming method using the same
CA2550091A1 (en) * 2003-12-19 2005-07-07 Elixir Pharmaceuticals, Inc. Methods of treating a disorder
PL1701940T3 (pl) * 2003-12-23 2008-11-28 H Lundbeck As Pochodne 2-(1H-indolilosulfanylo)benzyloaminy jako SSRI
SE528250C2 (sv) 2004-02-27 2006-10-03 Calignum Technologies Ab Komposition innefattande en initiator och ett förfarande för att behandla trä med kompositionen
JP4569142B2 (ja) * 2004-03-22 2010-10-27 コニカミノルタホールディングス株式会社 表示素子
JP4448730B2 (ja) * 2004-04-20 2010-04-14 富士フイルム株式会社 感光性組成物、該感光性組成物に用いられる化合物及び該感光性組成物を用いたパターン形成方法
WO2006006172A2 (en) 2004-07-15 2006-01-19 Ramot At Tel Aviv University Ltd. Use of anti-amyloid agents for treating and typing pathogen infections
EP1793816B1 (en) 2004-08-19 2012-01-04 Tel Aviv University Future Technology Development L.P. Compositions for treating amyloid associated diseases
EP1793272A4 (en) 2004-08-24 2008-01-23 Fujifilm Corp PHOTOGRAPHIC PHOTOSENSITIVE COLOR MATERIAL BASED ON SILVER HALIDE AND METHOD OF FORMING IMAGES
CN101068777A (zh) 2004-10-08 2007-11-07 万有制药株式会社 硫醚化合物的制备方法
WO2006063606A1 (en) 2004-12-16 2006-06-22 Pirelli & C. S.P.A. Process for manufacturing a thermoplastic elastomeric material

Also Published As

Publication number Publication date
SI1701940T1 (sl) 2008-10-31
IL176111A0 (en) 2006-10-05
JP4090491B2 (ja) 2008-05-28
BRPI0417858A (pt) 2007-04-27
ATE396970T1 (de) 2008-06-15
US20080176922A1 (en) 2008-07-24
RS50589B (sr) 2010-05-07
US7563908B2 (en) 2009-07-21
DE602004014190D1 (de) 2008-07-10
US20060160880A1 (en) 2006-07-20
AU2004303461B2 (en) 2011-04-28
US20080214645A1 (en) 2008-09-04
BRPI0417858B1 (pt) 2017-10-10
US7652150B2 (en) 2010-01-26
WO2005061455A1 (en) 2005-07-07
JP4091648B2 (ja) 2008-05-28
JP2007277254A (ja) 2007-10-25
US20080214644A1 (en) 2008-09-04
JP2008110984A (ja) 2008-05-15
PT1701940E (pt) 2008-07-30
DK1701940T3 (da) 2008-09-08
CY1108230T1 (el) 2014-02-12
EP1701940A1 (en) 2006-09-20
AU2004303461A1 (en) 2005-07-07
MXPA06007172A (es) 2006-08-23
US7737170B2 (en) 2010-06-15
IL176111A (en) 2011-10-31
EP1701940B1 (en) 2008-05-28
JP2007515436A (ja) 2007-06-14
HRP20110400T1 (hr) 2011-06-30
ES2303960T3 (es) 2008-09-01
CY1111733T1 (el) 2015-10-07
US7737171B2 (en) 2010-06-15
PL1701940T3 (pl) 2008-11-28

Similar Documents

Publication Publication Date Title
IL176111A0 (en) 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri
UA83875C2 (ru) Производные хинолина для применения в качестве микобактериальных ингибиторов
GEP20084551B (en) 4-phenylamino-quinazolin-6-yl-amides
UA102251C2 (ru) Производные аминодигидротиазина как ингибиторы васе для лечения болезни альцгеймера
SE0303180D0 (sv) Novel compounds
TW200726753A (en) 2,4-diamino-pyrimidines as aurora inhibitors
SE0302232D0 (sv) Novel Compounds
TW200531689A (en) Therapeutic agents
MY142988A (en) Novel aminobenzophenone compounds
MX2007011023A (es) 2-(4-oxo-4h-quinazolin-3-il) acetamidas y su uso como antagonistas de vasopresin v3.
IS8485A (is) Notkun á setnum 2-amínótetralínum í fyrirbyggjandi meðferð á Parkinsons-veiki
TW200800976A (en) New compounds for the treatment of neurological, psychiatric or pain disorders
TW200630374A (en) Thiazolyldihydroindazoles
NO20082096L (no) Azaindol-2-karboksamidderivativer
TW200745122A (en) New compounds I
DE602006010738D1 (de) Pyrroloä2,3-cüpyridinderivate
MX2010002938A (es) Derivados de (3-hidroxi-4-amino-butan-2-il)-3-(2-tiazol-2-il-pirro lidin-1-carbonil)benzamida y compuestos relacionados como inhibidores de beta-secretasa para tratar enfermedad de alzheimer.
MXPA05010000A (es) Derivados de p-diaminobenceno substituidos.
EA200602180A1 (ru) Производные 2-(1h-индолилсульфанил)ариламина для применения при лечении аффективных расстройств, боли, нгдв и стрессового недержания мочи
SE0401465D0 (sv) New substituted piperdines as modulators of dopamine neurotransmission
TW200734324A (en) Therapeutic agents
GB0514811D0 (en) Compounds
UA86873C2 (en) SUBSTITUTED ARYL 1,4-PYRAZlNE DERIVATIVES
MXPA05009282A (es) Derivados de anilina sustituidos.
UA94054C2 (en) Nitrocatechol derivatives as comt inhibitors